Streptococcal M1 protein triggers farnesyltransferase-dependentformation of CXC chemokines in alveolar macrophages and neutrophil infiltration of the lungs

Infection and Immunity

Volumn 80, Issue 11, 2012, Pages 3952-3959

  Zhang, Songen ^a   Rahman, Milladur ^a   Zhang, Su ^a   Jeppsson, Bengt ^a   Herwald, Heiko ^a   Thorlacius, Henrik ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; BACTERIAL PROTEIN; CD11B ANTIGEN; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; STREPTOCOCCAL M1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; IN VITRO STUDY; LEUKOCYTE COUNT; LUNG ALVEOLUS MACROPHAGE; LUNG EDEMA; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACUTE LUNG INJURY; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; CARRIER PROTEINS; CHEMOKINES, CXC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FARNESYLTRANSTRANSFERASE; FLOW CYTOMETRY; LUNG; MACROPHAGES, ALVEOLAR; MALE; METHIONINE; MICE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; PULMONARY EDEMA; REAL-TIME POLYMERASE CHAIN REACTION; STREPTOCOCCUS PYOGENES;

EID: 84867584481     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00696-12     Document Type: Article

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