Claudin expression profile separates Alzheimer's disease cases from normal aging and from vascular dementia cases

Journal of the Neurological Sciences

Volumn 322, Issue 1-2, 2012, Pages 184-186

  Spulber, Stefan ^a   Bogdanovic, Nenad ^b   Romanitan, Mihaela Oana ^c   Bajenaru, Ovidiu A ^c   Popescu, Bogdan O ^c,d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^d VICTOR BABES NATIONAL INSTITUTE OF PATHOLOGY   (Romania)

Author keywords

Alzheimer's disease; Claudin; Multivariate analysis; PLS DA; Tight junction proteins

Indexed keywords

CLAUDIN;

AGING; ALZHEIMER DISEASE; ARTICLE; CADASIL; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MULTIINFARCT DEMENTIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR AMYLOIDOSIS;

AGING; ALZHEIMER DISEASE; BRAIN; CLAUDINS; DEMENTIA, VASCULAR; FEMALE; HUMANS; MALE; NEUROGLIA; NEURONS; PRINCIPAL COMPONENT ANALYSIS;

EID: 84867576631     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2012.05.031     Document Type: Article

References (19)

1. U. Kniesel, and H. Wolburg Tight junctions of the blood-brain barrier Cell Mol Neurobiol 20 2000 57 76
2. L.L. Rubin The blood-brain barrier in and out of cell culture Curr Opin Neurobiol 1 1991 360 363
3. M.O. Romanitan, B.O. Popescu, B. Winblad, O.A. Bajenaru, and N. Bogdanovic Occludin is overexpressed in Alzheimer's disease and vascular dementia J Cell Mol Med 11 2007 569 579
4. M.O. Romanitan, B.O. Popescu, S. Spulber, O. Bǎjenaru, L.M. Popescu, and B. Winblad Altered expression of claudin family proteins in Alzheimer's disease and vascular dementia brains J Cell Mol Med 14 2010 1088 1100
5. B.O. Popescu, E.C. Toescu, L.M. Popescu, O. Bajenaru, D.F. Muresanu, and M. Schultzberg Blood-brain barrier alterations in ageing and dementia J Neurol Sci 283 2009 99 106
6. E. Westman, C. Spenger, L. Wahlund, and C. Lavebratt Carbamazepine treatment recovered low N-acetylaspartate+N-acetylaspartylglutamate (tNAA) levels in the megencephaly mouse BALB/cByJ-Kv1.1(mceph/mceph) Neurobiol Dis 26 2007 221 228
7. S. Spulber, T. Bartfai, B. Winblad, and M. Schultzberg Morphological and behavioral changes induced by transgenic overexpression of interleukin-1ra in the brain J Neurosci Res 89 2011 142 152
8. U. Rüetschi, H. Zetterberg, V.N. Podust, J. Gottfries, S. Li, and A. Hviid Simonsen Identification of CSF biomarkers for frontotemporal dementia using SELDI-TOF Exp Neurol 196 2005 273 281
9. J. Oberg, C. Spenger, F. Wang, A. Andersson, E. Westman, and P. Skoglund Age related changes in brain metabolites observed by 1H MRS in APP/PS1 mice Neurobiol Aging 29 2008 1423 1433
10. K. Pearson On lines and planes of closest fit to systems of points in space Philos Mag 2 1901 559 572
11. A.G.W. van Norden, E.J. van Dijk, K.F. de Laat, P. Scheltens, M.G.M. Olderikkert, and F.E. de Leeuw Dementia: Alzheimer pathology and vascular factors: from mutually exclusive to interaction Biochim Biophys Acta 1822 2012 340 349
12. R.D. Bell, and B.V. Zlokovic Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease Acta Neuropathol 118 2009 103 113
13. R.O. Weller, M. Subash, S.D. Preston, I. Mazanti, and R.O. Carare Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease Brain Pathol 18 2008 253 266
14. C.A. Hawkes, W. Härtig, J. Kacza, R. Schliebs, R.O. Weller, and J.A. Nicoll Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy Acta Neuropathol 121 2011 431 443
15. A. Escudero-Esparza, W.G. Jiang, and T.A. Martin The Claudin family and its role in cancer and metastasis Front Biosci 16 2011 1069 1083
16. J. Devaux, and A. Gow Tight junctions potentiate the insulative properties of small CNS myelinated axons J Cell Biol 183 2008 909 921
17. R.L. Bowen, J.P. Isley, and R.L. Atkinson An association of elevated serum gonadotropin concentrations and Alzheimer disease? J Neuroendocrinol 12 2000 351 354
18. G. Casadesus, M.R. Garrett, K.M. Webber, A.W. Hartzler, C.S. Atwood, and G. Perry The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease Drugs R&D 7 2006 187 193
19. J. Hu, Y. Wang, J. Zhou, C. Chen, F. Wang, and X. Li Differential gene expression in oligodendrocyte progenitor cells, oligodendrocytes and type II astrocytes Tohoku J Exp Med 223 2011 161 176