Investigation of cortical glutamate-glutamine and γ-aminobutyric acid in obsessive-compulsive disorder by proton magnetic resonance spectroscopy

Neuropsychopharmacology

Volumn 37, Issue 12, 2012, Pages 2684-2692

  Simpson, Helen B ^a,b   Shungu, Dikoma C ^c   Bender, James ^b   Mao, Xiangling ^c   Xu, Xiaoyan ^d   Slifstein, Mark ^d   Kegeles, Lawrence S ^a,d  

^a Anxiety Disord Clin in the Div of Clin Therapeut ^*  (United States)

^b Anxiety Disorders Clinic in the Division of Clinical Therapeutics   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

anterior cingulate cortex; dorsolateral prefrontal cortex; GABA; Glx; magnetic resonance spectroscopy; medial prefrontal cortex; OCD

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; GLUTAMINE; WATER;

ADULT; ANTERIOR CINGULATE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HYPOTHESIS; IMAGE ANALYSIS; MALE; MEDIAL PREFRONTAL CORTEX; OBSESSIVE COMPULSIVE DISORDER; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SEX DIFFERENCE;

ADOLESCENT; ADULT; AGE OF ONSET; BRAIN CHEMISTRY; CEREBRAL CORTEX; DATA INTERPRETATION, STATISTICAL; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GLUTAMINE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; OBSESSIVE-COMPULSIVE DISORDER; YOUNG ADULT;

EID: 84867571175     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.132     Document Type: Article

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