In vivo detection of gray and white matter differences in GABA concentration in the human brain

NeuroImage

Volumn 33, Issue 1, 2006, Pages 85-93

  Choi, In Young ^a,b   Lee, Sang Pil ^a,b   Merkle, Hellmut ^c   Shen, Jun ^d  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^d NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

CSI; GABA; Gray and white matter; Human brain in vivo; MRS

Indexed keywords

4 AMINOBUTYRIC ACID; CREATINE;

4 AMINOBUTYRIC ACID BRAIN LEVEL; ADULT; ARTICLE; BRAIN LEVEL; BRAIN RADIOGRAPHY; CONTROLLED STUDY; FRONTAL LOBE; GABAERGIC SYSTEM; GRAY MATTER; HUMAN; NONLINEAR REGRESSION ANALYSIS; NORMAL HUMAN; PARIETAL LOBE; PRIORITY JOURNAL; WHITE MATTER;

ADULT; ALGORITHMS; BRAIN CHEMISTRY; CALIBRATION; CEREBROSPINAL FLUID; CREATINE; FRONTAL LOBE; GAMMA-AMINOBUTYRIC ACID; GLUTATHIONE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LEAST-SQUARES ANALYSIS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; NONLINEAR DYNAMICS; PARIETAL LOBE;

EID: 33748875842     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2006.06.016     Document Type: Article

References (52)

1. Alderman J.L., and Shellenberger M.K. Gamma-aminobutyric acid (GABA) in the rat brain: re-evaluation of sampling procedures and the post-mortem increase. J. Neurochem. 22 (1974) 937-940
2. Banay-Schwartz M., Palkovits M., and Lajtha A. Heterogeneous distribution of functionally important amino acids in brain areas of adult and aging humans. Neurochem. Res. 18 (1993) 417-423
3. Blum B.P., and Mann J.J. The GABAergic system in schizophrenia. Int. J. Neuropsychopharmacol. 5 (2002) 159-179
4. Choi I.-Y., Tkac I., and Gruetter R. Single-shot, three-dimensional "non-echo" localization method for in vivo NMR spectroscopy. Magn. Reson. Med. 44 (2000) 387-394
5. Choi I.-Y., Lee S.-P., Merkle H., Branch C.A., and Shen J. In vivo measurement of GABA in the human brain using one- and two-dimensional selective multiple quantum spectroscopy at 3 Tesla. Proc. Int. Soc. Magn. Reson. Med. 11 (2003) 433
6. Choi I.-Y., Lee S.-P., Merkle H., and Shen J. Single-shot two-echo technique for simultaneous measurement of GABA and creatine in the human brain in vivo. Magn. Reson. Med. 51 (2004) 1115-1121
7. Choi I.-Y., Lee S.-P., Merkle H., and Shen J. In vivo detection of gray and white matter differences in GABA concentration in the human brain using chemical shift imaging of GABA. Proc. Int. Soc. Magn. Reson. Med. 12 (2004) 109
8. Choi I.-Y., Lee S.-P., and Shen J. In vivo single-shot three-dimensionally ocalized multiple quantum spectroscopy of GABA in the human brain with improved spectral selectivity. J. Magn. Reson. 172 (2005) 9-16
9. Choi I.-Y., Lee S.-P., and Shen J. Selective homonuclear Hartmann-Hahn transfer method for in vivo spectral editing in the human brain. Magn. Reson. Med. 53 (2005) 503-510
10. Cohen M.S., DuBois R.M., and Zeineh M.M. Rapid and effective correction of RF inhomogeneity for high field magnetic resonance imaging. Hum. Brain Mapp. 10 (2000) 204-211
11. de Graaf R.A., and Rothman D.L. Detection of gamma-aminobutyric acid (GABA) by longitudinal scalar order difference editing. J. Magn. Reson. 152 (2001) 124-131
12. Fahn S., and Cote L.J. Regional distribution of gamma-aminobutyric acid (GABA) in brain of the rhesus monkey. J. Neurochem. 15 (1968) 209-213
13. Grachev I.D., and Apkarian A.V. Chemical heterogeneity of the living human brain: a proton MR spectroscopy study on the effects of sex, age, and brain region. NeuroImage 11 (2000) 554-563
14. Gruetter R. Automatic, localized in vivo adjustment of all first- and second-order shim coils. Magn. Reson. Med. 29 (1993) 804-811
15. Hafner H.P., Muller S., and Seelig J. Numerical analysis of multislice MR excitation and inversion with multifrequency selective rf pulses. Magn. Reson. Med. 13 (1990) 279-292
16. Hanstock C.C., Coupland N.J., and Allen P.S. GABA X2 multiplet measured pre- and post-administration of vigabatrin in human brain. Magn. Reson. Med. 48 (2002) 617-623
17. Henry P.G., Dautry C., Hantraye P., and Bloch G. Brain GABA editing without macromolecule contamination. Magn. Reson. Med. 45 (2001) 517-520
18. Hetherington H.P., Mason G.F., Pan J.W., Ponder S.L., Vaughan J.T., Twieg D.B., and Pohost G.M. Evaluation of cerebral gray and white matter metabolite differences by spectroscopic imaging at 4.1T. Magn. Reson. Med. 32 (1994) 565-571
19. Hetherington H.P., Pan J.W., Mason G.F., Adams D., Vaughn M.J., Twieg D.B., and Pohost G.M. Quantitative 1H spectroscopic imaging of human brain at 4.1 T using image segmentation. Magn. Reson. Med. 36 (1996) 21-29
20. Hetherington H.P., Pan J.W., Chu W.J., Mason G.F., and Newcomer B.R. Biological and clinical MRS at ultra-high field. NMR Biomed. 10 (1997) 360-371
21. Hetherington H.P., Newcomer B.R., and Pan J.W. Measurements of human cerebral GABA at 4.1 T using numerically optimized editing pulses. Magn. Reson. Med. 39 (1998) 6-10
22. Hurd R., Sailasuta N., Srinivasan R., Vigneron D.B., Pelletier D., and Nelson S.J. Measurement of brain glutamate using TE-averaged PRESS at 3T. Magn. Reson. Med. 51 (2004) 435-440
23. Jensen J.E., Deb Frederick B., and Renshaw P.F. Grey and white matter GABA level differences in the human brain using two-dimensional, J-resolved spectroscopic imaging. NMR Biomed. 18 (2005) 570-576
24. Ke Y., Cohen B.M., Bang J.Y., Yang M., and Renshaw P.F. Assessment of GABA concentration in human brain using two-dimensional proton magnetic resonance spectroscopy. Psychiatry Res. 100 (2000) 169-178
25. Keltner J.R., Wald L.L., Christensen J.D., Maas L.C., Moore C.M., Cohen B.M., and Renshaw P.F. A technique for detecting GABA in the human brain with PRESS localization and optimized refocusing spectral editing radiofrequency pulses. Magn. Reson. Med. 36 (1996) 458-461
26. Keltner J.R., Wald L.L., Frederick B.D., and Renshaw P.F. In vivo detection of GABA in human brain using a localized double-quantum filter technique. Magn. Reson. Med. 37 (1997) 366-371
27. Knieriem K.M., Medina M.A., and Stavinoha W.B. The levels of GABA in mouse brain following tissue inactivation by microwave irradiation. J. Neurochem. 28 (1977) 885-886
28. Kreis R., Ernst T., and Ross B.D. Absolute quantification of water and metabolites in the human brain: II. Metabolite concentrations. J. Magn. Reson., B 102 (1993) 9-19
29. Lefauconnier J.M., Portemer C., and Chatagner F. Free amino acids and related substances in human glial tumours and in fetal brain: comparison with normal adult brain. Brain Res. 117 (1976) 105-113
30. Lewis D.A., Volk D.W., and Hashimoto T. Selective alterations in prefrontal cortical GABA neurotransmission in schizophrenia: a novel target for the treatment of working memory dysfunction. Psychopharmacology (Berlin) 174 (2004) 143-150
31. Merkle H., Driesel W., Andersen P., Adriany G., Ugurbil K., and Garwood M. Circularly polarized RF helmet coil for brain studies at 7 Tesla. Proc. Int. Soc. Mag. Reson. Med. 8 (2000) 565
32. Mescher M., Merkle H., Kirsch J., Garwood M., and Gruetter R. Simultaneous in vivo spectral editing and water suppression. NMR Biomed. 11 (1998) 266-272
33. Michaelis T., Merboldt K.D., Bruhn H., Hanicke W., and Frahm J. Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra. Radiology 187 (1993) 219-227
34. Minard F.N., and Mushahwar I.K. Synthesis of gamma-aminobutyric acid from a pool of glutamic acid in brain after decapitation. Life Sci. 5 (1966) 1409-1413
35. Olsen R.W., and DeLorey T.M. GABA and Glycine. In: Siegel G.J., Agranoff B.W., Albers R.W., Fisher S.K., and Uhler M.D. (Eds) (1999), Lippincott-Raven Publishers, Philadelphiain Book
36. Pan J.W., Twieg D.B., and Hetherington H.P. Quantitative spectroscopic imaging of the human brain. Magn. Reson. Med. 40 (1998) 363-369
37. Perry T.L., Hansen S., Berry K., Mok C., and Lesk D. Free amino acids and related compounds in biopsies of human brain. J. Neurochem. 18 (1971) 521-528
38. Petroff O.A., Pleban L.A., and Spencer D.D. Symbiosis between in vivo and in vitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain. Magn. Reson. Imaging 13 (1995) 1197-1211
39. Rothman D.L., Petroff O.A., Behar K.L., and Mattson R.H. Localized 1H NMR measurements of g-aminobutyric acid in human brain in vivo. Proc. Natl. Acad Sci. U. S. A. 90 (1993) 5662-5666
40. Seidl R., Cairns N., Singewald N., Kaehler S.T., and Lubec G. Differences between GABA levels in Alzheimer's disease and Down syndrome with Alzheimer-like neuropathology. Naunyn-Schmiedeberg's Arch. Pharmacol. 363 (2001) 139-145
41. Selemon L.D., Rajkowska G., and Goldman-Rakic P.S. Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17. Arch. Gen. Psychiatry 52 (1995) 805-818
42. Shen J., Shungu D.C., and Rothman D.L. In vivo chemical shift imaging of gamma-aminobutyric acid in the human brain. Magn. Reson. Med. 41 (1999) 35-42
43. Shen J., Rothman D.L., Hetherington H.P., and Pan J.W. Linear projection method for automatic slice shimming. Magn. Reson. Med. 42 (1999) 1082-1088
44. Shen J., Rothman D.L., and Brown P. In vivo GABA editing using a novel doubly selective multiple quantum filter. Magn. Reson. Med. 47 (2002) 447-454
45. Shen J., Yang J., Choi I.-Y., Li S.S., and Chen Z. A new strategy for in vivo spectral editing. Application to GABA editing using selective homonuclear polarization transfer spectroscopy. J. Magn. Reson. 170 (2004) 290-298
46. Terpstra M., Ugurbil K., and Gruetter R. Direct in vivo measurement of human cerebral GABA concentration using MEGA-editing at 7 Tesla. Magn. Reson. Med. 47 (2002) 1009-1012
47. van Kammen D.P. gamma-Aminobutyric acid (Gaba) and the dopamine hypothesis of schizophrenia. Am. J. Psychiatry 134 (1977) 138-143
48. van Kammen D.P., Petty F., Kelley M.E., Kramer G.L., Barry E.J., Yao J.K., Gurklis J.A., and Peters J.L. GABA and brain abnormalities in schizophrenia. Psychiatry Res. 82 (1998) 25-35
49. Wang Y., and Li S.J. Differentiation of metabolic concentrations between gray matter and white matter of human brain by in vivo 1H magnetic resonance spectroscopy. Magn. Reson. Med. 39 (1998) 28-33
50. Wang Z.J., Bergqvist C., Hunter J.V., Jin D., Wang D.J., Wehrli S., and Zimmerman R.A. In vivo measurement of brain metabolites using two-dimensional double-quantum MR spectroscopy-exploration of GABA levels in a ketogenic diet. Magn. Reson. Med. 49 (2003) 615-619
51. Weber-Fahr W., Ende G., Braus D.F., Bachert P., Soher B.J., Henn F.A., and Buchel C. A fully automated method for tissue segmentation and CSF-correction of proton MRSI metabolites corroborates abnormal hippocampal NAA in schizophrenia. NeuroImage 16 (2002) 49-60
52. Wilman A.H., and Allen P.S. Yield enhancement of a double-quantum filter sequence designed for the edited detection of GABA. J. Magn. Reson., B 109 (1995) 169-174