-
1
-
-
0029740474
-
Modulation of c-Myc activity and apoptosis in vivo
-
Alarcon RM, Rupnow BA, Graeber TG, Knox SJ, Giaccia AJ,. 1996. Modulation of c-Myc activity and apoptosis in vivo. Cancer Res 56: 4315-4319.
-
(1996)
Cancer Res
, vol.56
, pp. 4315-4319
-
-
Alarcon, R.M.1
Rupnow, B.A.2
Graeber, T.G.3
Knox, S.J.4
Giaccia, A.J.5
-
2
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF,. 2003. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100: 3983-3988.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
3
-
-
3843062504
-
Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma
-
Amin HM, McDonnell TJ, Ma Y, Lin Q, Fujio Y, Kunisada K, Leventaki V, Das P, Rassidakis GZ, Cutler C, Medeiros LJ, Lai R,. 2004. Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma. Oncogene 23: 5426-5434.
-
(2004)
Oncogene
, vol.23
, pp. 5426-5434
-
-
Amin, H.M.1
McDonnell, T.J.2
Ma, Y.3
Lin, Q.4
Fujio, Y.5
Kunisada, K.6
Leventaki, V.7
Das, P.8
Rassidakis, G.Z.9
Cutler, C.10
Medeiros, L.J.11
Lai, R.12
-
4
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN,. 2006. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444: 756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
5
-
-
78650979504
-
DNA-damage response in tissue-specific and cancer stem cells
-
Blanpain C, Mohrin M, Sotiropoulou PA, Passegue E,. 2011. DNA-damage response in tissue-specific and cancer stem cells. Cell Stem Cell 8: 16-29.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 16-29
-
-
Blanpain, C.1
Mohrin, M.2
Sotiropoulou, P.A.3
Passegue, E.4
-
6
-
-
60849117508
-
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, Holland EC,. 2009. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 4: 226-235.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
Fomchenko, E.I.4
Huse, J.T.5
Brennan, C.W.6
Holland, E.C.7
-
7
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
Campisi J, d'Adda di Fagagna F,. 2007. Cellular senescence: When bad things happen to good cells. Nat Rev Mol Cell Biol 8: 729-740.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 729-740
-
-
Campisi, J.1
D'Adda Di Fagagna, F.2
-
8
-
-
16844364151
-
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
-
Cartwright P, McLean C, Sheppard A, Rivett D, Jones K, Dalton S,. 2005. LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 132: 885-896.
-
(2005)
Development
, vol.132
, pp. 885-896
-
-
Cartwright, P.1
McLean, C.2
Sheppard, A.3
Rivett, D.4
Jones, K.5
Dalton, S.6
-
10
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean M, Fojo T, Bates S,. 2005. Tumour stem cells and drug resistance. Nat Rev Cancer 5: 275-284.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
11
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN, Qian D, Lam JS, Ailles LE, Wong M, Joshua B, Kaplan MJ, Wapnir I, Dirbas FM, Somlo G, Garberoglio C, Paz B, Shen J, Lau SK, Quake SR, Brown JM, Weissman IL, Clarke MF,. 2009. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458: 780-783.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
Kalisky, T.4
Dorie, M.J.5
Kulp, A.N.6
Qian, D.7
Lam, J.S.8
Ailles, L.E.9
Wong, M.10
Joshua, B.11
Kaplan, M.J.12
Wapnir, I.13
Dirbas, F.M.14
Somlo, G.15
Garberoglio, C.16
Paz, B.17
Shen, J.18
Lau, S.K.19
Quake, S.R.20
Brown, J.M.21
Weissman, I.L.22
Clarke, M.F.23
more..
-
12
-
-
34250308322
-
Apoptosis: A review of programmed cell death
-
Elmore S,. 2007. Apoptosis: A review of programmed cell death. Toxicol Pathol 35: 495-516.
-
(2007)
Toxicol Pathol
, vol.35
, pp. 495-516
-
-
Elmore, S.1
-
13
-
-
39749178390
-
Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo
-
Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM, Scadden DT,. 2008. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell 2: 274-283.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 274-283
-
-
Fleming, H.E.1
Janzen, V.2
Lo Celso, C.3
Guo, J.4
Leahy, K.M.5
Kronenberg, H.M.6
Scadden, D.T.7
-
14
-
-
74949090309
-
The therapeutic promise of the cancer stem cell concept
-
Frank NY, Schatton T, Frank MH,. 2010. The therapeutic promise of the cancer stem cell concept. J Clin Invest 120: 41-50.
-
(2010)
J Clin Invest
, vol.120
, pp. 41-50
-
-
Frank, N.Y.1
Schatton, T.2
Frank, M.H.3
-
15
-
-
77749233744
-
Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage
-
Guerra L, Albihn A, Tronnersjo S, Yan Q, Guidi R, Stenerlow B, Sterzenbach T, Josenhans C, Fox JG, Schauer DB, Thelestam M, Larsson LG, Henriksson M, Frisan T,. 2010. Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage. PLoS ONE 5: e8924.
-
(2010)
PLoS ONE
, vol.5
-
-
Guerra, L.1
Albihn, A.2
Tronnersjo, S.3
Yan, Q.4
Guidi, R.5
Stenerlow, B.6
Sterzenbach, T.7
Josenhans, C.8
Fox, J.G.9
Schauer, D.B.10
Thelestam, M.11
Larsson, L.G.12
Henriksson, M.13
Frisan, T.14
-
17
-
-
65349130616
-
Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines
-
Huang D, Gao Q, Guo L, Zhang C, Jiang W, Li H, Wang J, Han X, Shi Y, Lu SH,. 2009. Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines. Stem Cells Dev 18: 465-473.
-
(2009)
Stem Cells Dev
, vol.18
, pp. 465-473
-
-
Huang, D.1
Gao, Q.2
Guo, L.3
Zhang, C.4
Jiang, W.5
Li, H.6
Wang, J.7
Han, X.8
Shi, Y.9
Lu, S.H.10
-
18
-
-
34848915148
-
Gadd45a regulates beta-catenin distribution and maintains cell-cell adhesion/contact
-
Ji J, Liu R, Tong T, Song Y, Jin S, Wu M, Zhan Q,. 2007. Gadd45a regulates beta-catenin distribution and maintains cell-cell adhesion/contact. Oncogene 26: 6396-6405.
-
(2007)
Oncogene
, vol.26
, pp. 6396-6405
-
-
Ji, J.1
Liu, R.2
Tong, T.3
Song, Y.4
Jin, S.5
Wu, M.6
Zhan, Q.7
-
19
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan MB, Bartek J,. 2004. Cell-cycle checkpoints and cancer. Nature 432: 316-323.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
20
-
-
0033521595
-
STAT3 is required for the gp130-mediated full activation of the c-myc gene
-
Kiuchi N, Nakajima K, Ichiba M, Fukada T, Narimatsu M, Mizuno K, Hibi M, Hirano T,. 1999. STAT3 is required for the gp130-mediated full activation of the c-myc gene. J Exp Med 189: 63-73.
-
(1999)
J Exp Med
, vol.189
, pp. 63-73
-
-
Kiuchi, N.1
Nakajima, K.2
Ichiba, M.3
Fukada, T.4
Narimatsu, M.5
Mizuno, K.6
Hibi, M.7
Hirano, T.8
-
21
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine AJ,. 1997. p53, the cellular gatekeeper for growth and division. Cell 88: 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
22
-
-
75749146169
-
Coexistence of quiescent and active adult stem cells in mammals
-
Li L, Clevers H,. 2010. Coexistence of quiescent and active adult stem cells in mammals. Science 327: 542-545.
-
(2010)
Science
, vol.327
, pp. 542-545
-
-
Li, L.1
Clevers, H.2
-
23
-
-
79957846955
-
The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells
-
Li H, Gao Q, Guo L, Lu SH,. 2011. The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. Cancer Biol Ther 11: 950-958.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 950-958
-
-
Li, H.1
Gao, Q.2
Guo, L.3
Lu, S.H.4
-
24
-
-
79952003900
-
DNA damage response in adult stem cells: Pathways and consequences
-
Mandal PK, Blanpain C, Rossi DJ,. 2011. DNA damage response in adult stem cells: Pathways and consequences. Nat Rev Mol Cell Biol 12: 198-202.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 198-202
-
-
Mandal, P.K.1
Blanpain, C.2
Rossi, D.J.3
-
25
-
-
77953693899
-
Targeting HedgehogâA cancer stem cell pathway
-
Merchant AA, Matsui W,. 2010. Targeting HedgehogâA cancer stem cell pathway. Clin Cancer Res 16: 3130-3140.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3130-3140
-
-
Merchant, A.A.1
Matsui, W.2
-
26
-
-
38349132624
-
Deconstructing stem cell self-renewal: Genetic insights into cell-cycle regulation
-
Orford KW, Scadden DT,. 2008. Deconstructing stem cell self-renewal: Genetic insights into cell-cycle regulation. Nat Rev Genet 9: 115-128.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 115-128
-
-
Orford, K.W.1
Scadden, D.T.2
-
27
-
-
77953700950
-
Targeting Notch to target cancer stem cells
-
Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, Miele L,. 2010. Targeting Notch to target cancer stem cells. Clin Cancer Res 16: 3141-3152.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3141-3152
-
-
Pannuti, A.1
Foreman, K.2
Rizzo, P.3
Osipo, C.4
Golde, T.5
Osborne, B.6
Miele, L.7
-
28
-
-
78249250559
-
Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized
-
Quintana E, Shackleton M, Foster HR, Fullen DR, Sabel MS, Johnson TM, Morrison SJ,. 2010. Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized. Cancer Cell 18: 510-523.
-
(2010)
Cancer Cell
, vol.18
, pp. 510-523
-
-
Quintana, E.1
Shackleton, M.2
Foster, H.R.3
Fullen, D.R.4
Sabel, M.S.5
Johnson, T.M.6
Morrison, S.J.7
-
29
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL,. 2001. Stem cells, cancer, and cancer stem cells. Nature 414: 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
30
-
-
77952502408
-
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
-
Roesch A, Fukunaga-Kalabis M, Schmidt EC, Zabierowski SE, Brafford PA, Vultur A, Basu D, Gimotty P, Vogt T, Herlyn M,. 2010. A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. Cell 141: 583-594.
-
(2010)
Cell
, vol.141
, pp. 583-594
-
-
Roesch, A.1
Fukunaga-Kalabis, M.2
Schmidt, E.C.3
Zabierowski, S.E.4
Brafford, P.A.5
Vultur, A.6
Basu, D.7
Gimotty, P.8
Vogt, T.9
Herlyn, M.10
-
31
-
-
27844605411
-
Onzin, a c-Myc-repressed target, promotes survival and transformation by modulating the Akt-Mdm2-p53 pathway
-
Rogulski K, Li Y, Rothermund K, Pu L, Watkins S, Yi F, Prochownik EV,. 2005. Onzin, a c-Myc-repressed target, promotes survival and transformation by modulating the Akt-Mdm2-p53 pathway. Oncogene 24: 7524-7541.
-
(2005)
Oncogene
, vol.24
, pp. 7524-7541
-
-
Rogulski, K.1
Li, Y.2
Rothermund, K.3
Pu, L.4
Watkins, S.5
Yi, F.6
Prochownik, E.V.7
-
32
-
-
81855184457
-
Cancer stem cells. VEGF promotes stemness
-
Seton-Rogers S,. 2011. Cancer stem cells. VEGF promotes stemness. Nat Rev Cancer 11: 831.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 831
-
-
Seton-Rogers, S.1
-
33
-
-
77950809059
-
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
-
Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran S, McDermott U, Azizian N, Zou L, Fischbach MA, Wong KK, Brandstetter K, Wittner B, Ramaswamy S, Classon M, Settleman J,. 2010. A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell 141: 69-680.
-
(2010)
Cell
, vol.141
, pp. 69-680
-
-
Sharma, S.V.1
Lee, D.Y.2
Li, B.3
Quinlan, M.P.4
Takahashi, F.5
Maheswaran, S.6
McDermott, U.7
Azizian, N.8
Zou, L.9
Fischbach, M.A.10
Wong, K.K.11
Brandstetter, K.12
Wittner, B.13
Ramaswamy, S.14
Classon, M.15
Settleman, J.16
-
34
-
-
57049114832
-
The genetics of the p53 pathway, apoptosis and cancer therapy
-
Vazquez A, Bond EE, Levine AJ, Bond GL,. 2008. The genetics of the p53 pathway, apoptosis and cancer therapy. Nat Rev Drug Discov 7: 979-987.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 979-987
-
-
Vazquez, A.1
Bond, E.E.2
Levine, A.J.3
Bond, G.L.4
-
35
-
-
77951975325
-
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
-
Vermeulen L, De Sousa EMF, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP,. 2010. Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat Cell Biol 12: 468-476.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 468-476
-
-
Vermeulen, L.1
De Sousa, E.M.F.2
Van Der Heijden, M.3
Cameron, K.4
De Jong, J.H.5
Borovski, T.6
Tuynman, J.B.7
Todaro, M.8
Merz, C.9
Rodermond, H.10
Sprick, M.R.11
Kemper, K.12
Richel, D.J.13
Stassi, G.14
Medema, J.P.15
-
36
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
Visvader JE, Lindeman GJ,. 2008. Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions. Nat Rev Cancer 8: 755-768.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
38
-
-
34248529666
-
Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
-
Wang J, Guo LP, Chen LZ, Zeng YX, Lu SH,. 2007. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res 67: 3716-3724.
-
(2007)
Cancer Res
, vol.67
, pp. 3716-3724
-
-
Wang, J.1
Guo, L.P.2
Chen, L.Z.3
Zeng, Y.X.4
Lu, S.H.5
-
39
-
-
0035967099
-
Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc
-
Yang W, Shen J, Wu M, Arsura M, FitzGerald M, Suldan Z, Kim DW, Hofmann CS, Pianetti S, Romieu-Mourez R, Freedman LP, Sonenshein GE,. 2001. Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc. Oncogene 20: 1688-1702.
-
(2001)
Oncogene
, vol.20
, pp. 1688-1702
-
-
Yang, W.1
Shen, J.2
Wu, M.3
Arsura, M.4
Fitzgerald, M.5
Suldan, Z.6
Kim, D.W.7
Hofmann, C.S.8
Pianetti, S.9
Romieu-Mourez, R.10
Freedman, L.P.11
Sonenshein, G.E.12
-
40
-
-
36048963331
-
Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance
-
Zhou J, Wulfkuhle J, Zhang H, Gu P, Yang Y, Deng J, Margolick JB, Liotta LA, Petricoin E III, Zhang Y,. 2007. Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance. Proc Natl Acad Sci USA 104: 16158-16163.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 16158-16163
-
-
Zhou, J.1
Wulfkuhle, J.2
Zhang, H.3
Gu, P.4
Yang, Y.5
Deng, J.6
Margolick, J.B.7
Liotta, L.A.8
Petricoin Iii, E.9
Zhang, Y.10
-
41
-
-
80052281899
-
P57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70
-
Zou P, Yoshihara H, Hosokawa K, Tai I, Shinmyozu K, Tsukahara F, Maru Y, Nakayama K, Nakayama KI, Suda T,. 2011. p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell 9: 247-261.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 247-261
-
-
Zou, P.1
Yoshihara, H.2
Hosokawa, K.3
Tai, I.4
Shinmyozu, K.5
Tsukahara, F.6
Maru, Y.7
Nakayama, K.8
Nakayama, K.I.9
Suda, T.10
|