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Volumn 89, Issue , 2012, Pages 65-83

Opportunities and challenges for genome sequencing in the clinic

Author keywords

Association; Epilepsy; Gene mapping; Genetics; GWAS; Linkage; Next generation sequencing; Pharmacogenetics; Study design

Indexed keywords


EID: 84867548992     PISSN: 18761623     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-394287-6.00003-3     Document Type: Chapter
Times cited : (9)

References (76)
  • 4
    • 84055193413 scopus 로고    scopus 로고
    • Linkage analysis in the next-generation sequencing era
    • J.E. Bailey-Wilson, and A.F. Wilson Linkage analysis in the next-generation sequencing era Human Heredity 72 4 2011 228 236
    • (2011) Human Heredity , vol.72 , Issue.4 , pp. 228-236
    • Bailey-Wilson, J.E.1    Wilson, A.F.2
  • 5
    • 77950865193 scopus 로고    scopus 로고
    • Towards a modern classification of the epilepsies?
    • A.T. Berg, and J.H. Cross Towards a modern classification of the epilepsies? Lancet Neurology 9 5 2010 459 461
    • (2010) Lancet Neurology , vol.9 , Issue.5 , pp. 459-461
    • Berg, A.T.1    Cross, J.H.2
  • 6
    • 0031748082 scopus 로고    scopus 로고
    • Epilepsies in twins: Genetics of the major epilepsy syndromes
    • DOI 10.1002/ana.410430405
    • S.F. Berkovic, R.A. Howell, D.A. Hay, and J.L. Hopper Epilepsies in twins: Genetics of the major epilepsy syndromes Annals of Neurology 43 4 1998 435 445 (Pubitemid 28231717)
    • (1998) Annals of Neurology , vol.43 , Issue.4 , pp. 435-445
    • Berkovic, S.F.1    Howell, R.A.2    Hay, D.A.3    Hopper, J.L.4
  • 7
    • 33746302765 scopus 로고    scopus 로고
    • Human epilepsies: Interaction of genetic and acquired factors
    • DOI 10.1016/j.tins.2006.05.009, PII S016622360600110X
    • S.F. Berkovic, J.C. Mulley, I.E. Scheffer, and S. Petrou Human epilepsies: Interaction of genetic and acquired factors Trends in Neurosciences 29 7 2006 391 397 (Pubitemid 44108246)
    • (2006) Trends in Neurosciences , vol.29 , Issue.7 , pp. 391-397
    • Berkovic, S.F.1    Mulley, J.C.2    Scheffer, I.E.3    Petrou, S.4
  • 8
    • 0019302053 scopus 로고
    • Construction of a genetic linkage map in man using restriction fragment length polymorphisms
    • D. Botstein, R.L. White, M. Skolnick, and R.W. Davis Construction of a genetic linkage map in man using restriction fragment length polymorphisms American Journal of Human Genetics 32 3 1980 314 331 (Pubitemid 11105557)
    • (1980) American Journal of Human Genetics , vol.32 , Issue.3 , pp. 314-331
    • Botstein, D.1    White, R.L.2    Skolnick, M.3    Davis, R.W.4
  • 9
    • 0036980077 scopus 로고    scopus 로고
    • Interpretation of genetic association studies in complex disease
    • H. Campbell, and I. Rudan Interpretation of genetic association studies in complex disease The Pharmacogenomics Journal 2 6 2002 349 360 (Pubitemid 36175797)
    • (2002) Pharmacogenomics Journal , vol.2 , Issue.6 , pp. 349-360
    • Campbell, H.1    Rudan, I.2
  • 10
    • 77952818259 scopus 로고    scopus 로고
    • Genetic overlap between autism, schizophrenia and bipolar disorder
    • L.S. Carroll, and M.J. Owen Genetic overlap between autism, schizophrenia and bipolar disorder Genome Medicine 1 10 2009 102
    • (2009) Genome Medicine , vol.1 , Issue.10 , pp. 102
    • Carroll, L.S.1    Owen, M.J.2
  • 11
    • 23444437212 scopus 로고    scopus 로고
    • Failure to replicate previously reported genetic associations with sporadic temporal lobe epilepsy: Where to from here?
    • DOI 10.1093/brain/awh524
    • G.L. Cavalleri, J.M. Lynch, C. Depondt, M.W. Burley, N.W. Wood, and S.M. Sisodiya Failure to replicate previously reported genetic associations with sporadic temporal lobe epilepsy: Where to from here? Brain 128 Pt 8 2005 1832 1840 (Pubitemid 41373654)
    • (2005) Brain , vol.128 , Issue.8 , pp. 1832-1840
    • Cavalleri, G.L.1    Lynch, J.M.2    Depondt, C.3    Burley, M.-W.4    Wood, N.W.5    Sisodiya, S.M.6    Goldstein, D.B.7
  • 14
    • 1842784823 scopus 로고    scopus 로고
    • Medical genetics: A marker for Stevens-Johnson syndrome
    • W.H. Chung, S.I. Hung, H.S. Hong, M.S. Hsih, L.C. Yang, and H.C. Ho Medical genetics: A marker for Stevens-Johnson syndrome Nature 428 6982 2004 486
    • (2004) Nature , vol.428 , Issue.6982 , pp. 486
    • Chung, W.H.1    Hung, S.I.2    Hong, H.S.3    Hsih, M.S.4    Yang, L.C.5    Ho, H.C.6
  • 15
    • 3843056691 scopus 로고    scopus 로고
    • Multiple rare alleles contribute to low plasma levels of HDL cholesterol
    • DOI 10.1126/science.1099870
    • J.C. Cohen, R.S. Kiss, A. Pertsemlidis, Y.L. Marcel, R. McPherson, and H.H. Hobbs Multiple rare alleles contribute to low plasma levels of HDL cholesterol Science 305 5685 2004 869 872 (Pubitemid 39038422)
    • (2004) Science , vol.305 , Issue.5685 , pp. 869-872
    • Cohen, J.C.1    Kiss, R.S.2    Pertsemlidis, A.3    Marcel, Y.L.4    McPherson, R.5    Hobbs, H.H.6
  • 16
    • 84860570409 scopus 로고    scopus 로고
    • Next-generation sequencing: Ready for the clinics?
    • A.N. Desai, and A. Jere Next-generation sequencing: Ready for the clinics? Clinical Genetics 81 6 2012 503 510
    • (2012) Clinical Genetics , vol.81 , Issue.6 , pp. 503-510
    • Desai, A.N.1    Jere, A.2
  • 17
    • 16544380910 scopus 로고    scopus 로고
    • Genomic control to the extreme
    • author reply 1131
    • B. Devlin, S.A. Bacanu, and K. Roeder Genomic control to the extreme Nature Genetics 36 11 2004 1129 1130 author reply 1131
    • (2004) Nature Genetics , vol.36 , Issue.11 , pp. 1129-1130
    • Devlin, B.1    Bacanu, S.A.2    Roeder, K.3
  • 21
    • 84865023341 scopus 로고    scopus 로고
    • Epi4K: Gene discovery in 4,000 genomes
    • Epi4K: Gene discovery in 4,000 genomes. (2012). Epilepsia, 53(8), 1457-1467.
    • (2012) Epilepsia , vol.53 , Issue.8 , pp. 1457-1467
  • 22
    • 0018087680 scopus 로고
    • Analysis of the β-δ-globin gene loci in normal and Hb Lepore DNA: Direct determination of gene linkage and intergene distance
    • R.A. Flavell, J.M. Kooter, E. De Boer, P.F. Little, and R. Williamson Analysis of the beta-delta-globin gene loci in normal and Hb Lepore DNA: Direct determination of gene linkage and intergene distance Cell 15 1 1978 25 41 (Pubitemid 9027508)
    • (1978) Cell , vol.15 , Issue.1 , pp. 25-41
    • Flavell, R.A.1    Kooter, J.M.2    De Boer, E.3
  • 23
    • 79951472909 scopus 로고    scopus 로고
    • Charting a course for genomic medicine from base pairs to bedside
    • E.D. Green, and M.S. Guyer Charting a course for genomic medicine from base pairs to bedside Nature 470 7333 2011 204 213
    • (2011) Nature , vol.470 , Issue.7333 , pp. 204-213
    • Green, E.D.1    Guyer, M.S.2
  • 24
    • 84863012719 scopus 로고    scopus 로고
    • Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese
    • Y. Guo, L.W. Baum, P.C. Sham, V. Wong, P.W. Ng, and C.H. Lui Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese Human Molecular Genetics 21 5 2012 1184 1189
    • (2012) Human Molecular Genetics , vol.21 , Issue.5 , pp. 1184-1189
    • Guo, Y.1    Baum, L.W.2    Sham, P.C.3    Wong, V.4    Ng, P.W.5    Lui, C.H.6
  • 25
    • 84864928152 scopus 로고    scopus 로고
    • Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy
    • E.L. Heinzen, C. Depondt, G.L. Cavalleri, E.K. Ruzzo, N.M. Walley, and A.C. Need Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy The American Journal of Human Genetics 91 2 2012 293 302
    • (2012) The American Journal of Human Genetics , vol.91 , Issue.2 , pp. 293-302
    • Heinzen, E.L.1    Depondt, C.2    Cavalleri, G.L.3    Ruzzo, E.K.4    Walley, N.M.5    Need, A.C.6
  • 28
    • 38949127199 scopus 로고    scopus 로고
    • Navigating the channels and beyond: Unravelling the genetics of the epilepsies
    • DOI 10.1016/S1474-4422(08)70039-5, PII S1474442208700395
    • I. Helbig, I.E. Scheffer, J.C. Mulley, and S.F. Berkovic Navigating the channels and beyond: Unravelling the genetics of the epilepsies Lancet Neurology 7 3 2008 231 245 (Pubitemid 351215982)
    • (2008) The Lancet Neurology , vol.7 , Issue.3 , pp. 231-245
    • Helbig, I.1    Scheffer, I.E.2    Mulley, J.C.3    Berkovic, S.F.4
  • 30
    • 80052859044 scopus 로고    scopus 로고
    • Genomics, health care, and society
    • K.L. Hudson Genomics, health care, and society The New England Journal of Medicine 365 11 2011 1033 1041
    • (2011) The New England Journal of Medicine , vol.365 , Issue.11 , pp. 1033-1041
    • Hudson, K.L.1
  • 31
    • 4744365530 scopus 로고    scopus 로고
    • Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms
    • C.C. Hung, C.J. Lin, C.C. Chen, C.J. Chang, and H.H. Liou Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms Therapeutic Drug Monitoring 26 5 2004 534 540
    • (2004) Therapeutic Drug Monitoring , vol.26 , Issue.5 , pp. 534-540
    • Hung, C.C.1    Lin, C.J.2    Chen, C.C.3    Chang, C.J.4    Liou, H.H.5
  • 32
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International HapMap Consortium A haplotype map of the human genome Nature 437 7063 2005 1299 1320
    • (2005) Nature , vol.437 , Issue.7063 , pp. 1299-1320
    • Hapmap Consortium, I.1
  • 33
    • 77954356949 scopus 로고    scopus 로고
    • Common genetic variation and susceptibility to partial epilepsies: A genome-wide association study
    • D. Kasperaviciute, C.B. Catarino, E.L. Heinzen, C. Depondt, G.L. Cavalleri, and L.O. Caboclo Common genetic variation and susceptibility to partial epilepsies: A genome-wide association study Brain 133 Pt 7 2010 2136 2147
    • (2010) Brain , vol.133 , Issue.PART 7 , pp. 2136-2147
    • Kasperaviciute, D.1    Catarino, C.B.2    Heinzen, E.L.3    Depondt, C.4    Cavalleri, G.L.5    Caboclo, L.O.6
  • 34
    • 0042932513 scopus 로고    scopus 로고
    • Epileptic seizures and syndromes in twins: The importance of genetic factors
    • DOI 10.1016/S0920-1211(03)00117-7
    • M.J. Kjeldsen, L.A. Corey, K. Christensen, and M.L. Friis Epileptic seizures and syndromes in twins: The importance of genetic factors Epilepsy Research 55 1-2 2003 137 146 (Pubitemid 37011378)
    • (2003) Epilepsy Research , vol.55 , Issue.1-2 , pp. 137-146
    • Kjeldsen, M.J.1    Corey, L.A.2    Christensen, K.3    Friis, M.L.4
  • 38
    • 77957947562 scopus 로고    scopus 로고
    • Hundreds of variants clustered in genomic loci and biological pathways affect human height
    • H. Lango Allen, K. Estrada, G. Lettre, S.I. Berndt, M.N. Weedon, and F. Rivadeneira Hundreds of variants clustered in genomic loci and biological pathways affect human height Nature 467 7317 2010 832 838
    • (2010) Nature , vol.467 , Issue.7317 , pp. 832-838
    • Lango Allen, H.1    Estrada, K.2    Lettre, G.3    Berndt, S.I.4    Weedon, M.N.5    Rivadeneira, F.6
  • 40
    • 84865020270 scopus 로고    scopus 로고
    • Targeted next generation sequencing as a diagnostic tool in epileptic disorders
    • J.R. Lemke, E. Riesch, T. Scheurenbrand, M. Schubach, C. Wilhelm, and I. Steiner Targeted next generation sequencing as a diagnostic tool in epileptic disorders Epilepsia 53 8 2012 1387 1398
    • (2012) Epilepsia , vol.53 , Issue.8 , pp. 1387-1398
    • Lemke, J.R.1    Riesch, E.2    Scheurenbrand, T.3    Schubach, M.4    Wilhelm, C.5    Steiner, I.6
  • 42
    • 82355169007 scopus 로고    scopus 로고
    • Using extreme phenotype sampling to identify the rare causal variants of quantitative traits in association studies
    • D. Li, J.P. Lewinger, W.J. Gauderman, C.E. Murcray, and D. Conti Using extreme phenotype sampling to identify the rare causal variants of quantitative traits in association studies Genetic Epidemiology 35 8 2011 790 799
    • (2011) Genetic Epidemiology , vol.35 , Issue.8 , pp. 790-799
    • Li, D.1    Lewinger, J.P.2    Gauderman, W.J.3    Murcray, C.E.4    Conti, D.5
  • 43
    • 38149108354 scopus 로고    scopus 로고
    • A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs
    • C. Lonjou, N. Borot, P. Sekula, N. Ledger, L. Thomas, and S. Halevy A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs Pharmacogenetics and Genomics 18 2 2008 99 107
    • (2008) Pharmacogenetics and Genomics , vol.18 , Issue.2 , pp. 99-107
    • Lonjou, C.1    Borot, N.2    Sekula, P.3    Ledger, N.4    Thomas, L.5    Halevy, S.6
  • 48
    • 77956628767 scopus 로고    scopus 로고
    • Genome-wide copy number variation in epilepsy: Novel susceptibility loci in idiopathic generalized and focal epilepsies
    • H.C. Mefford, H. Muhle, P. Ostertag, S. von Spiczak, K. Buysse, and C. Baker Genome-wide copy number variation in epilepsy: Novel susceptibility loci in idiopathic generalized and focal epilepsies PLoS Genetics 6 5 2010 e1000962
    • (2010) PLoS Genetics , vol.6 , Issue.5 , pp. 1000962
    • Mefford, H.C.1    Muhle, H.2    Ostertag, P.3    Von Spiczak, S.4    Buysse, K.5    Baker, C.6
  • 49
    • 79952575575 scopus 로고    scopus 로고
    • Epilepsy and the new cytogenetics
    • J.C. Mulley, and H.C. Mefford Epilepsy and the new cytogenetics Epilepsia 52 3 2011 423 432
    • (2011) Epilepsia , vol.52 , Issue.3 , pp. 423-432
    • Mulley, J.C.1    Mefford, H.C.2
  • 50
    • 84860712363 scopus 로고    scopus 로고
    • Patterns and rates of exonic de novo mutations in autism spectrum disorders
    • B.M. Neale, Y. Kou, L. Liu, A. Ma'ayan, K.E. Samocha, and A. Sabo Patterns and rates of exonic de novo mutations in autism spectrum disorders Nature 485 7397 2012 242 245
    • (2012) Nature , vol.485 , Issue.7397 , pp. 242-245
    • Neale, B.M.1    Kou, Y.2    Liu, L.3    Ma'Ayan, A.4    Samocha, K.E.5    Sabo, A.6
  • 51
    • 84863541347 scopus 로고    scopus 로고
    • An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people
    • M.R. Nelson, D. Wegmann, M.G. Ehm, D. Kessner, P. St Jean, and C. Verzilli An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people Science 337 2012 100 104
    • (2012) Science , vol.337 , pp. 100-104
    • Nelson, M.R.1    Wegmann, D.2    Ehm, M.G.3    Kessner, D.4    St Jean, P.5    Verzilli, C.6
  • 53
    • 0031897530 scopus 로고    scopus 로고
    • Are generalized and localization-related epilepsies genetically distinct?
    • DOI 10.1001/archneur.55.3.339
    • R. Ottman, J.H. Lee, W.A. Hauser, and N. Risch Are generalized and localization-related epilepsies genetically distinct? Archives of Neurology 55 3 1998 339 344 (Pubitemid 28146198)
    • (1998) Archives of Neurology , vol.55 , Issue.3 , pp. 339-344
    • Ottman, R.1    Lee, J.H.2    Hauser, W.A.3    Risch, N.4
  • 54
    • 79551600984 scopus 로고    scopus 로고
    • Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population
    • T. Ozeki, T. Mushiroda, A. Yowang, A. Takahashi, M. Kubo, and Y. Shirakata Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population Human Molecular Genetics 20 5 2011 1034 1041
    • (2011) Human Molecular Genetics , vol.20 , Issue.5 , pp. 1034-1041
    • Ozeki, T.1    Mushiroda, T.2    Yowang, A.3    Takahashi, A.4    Kubo, M.5    Shirakata, Y.6
  • 56
    • 77956263092 scopus 로고    scopus 로고
    • Genetic evaluation and counseling for epilepsy
    • D.K. Pal, A.W. Pong, and W.K. Chung Genetic evaluation and counseling for epilepsy Nature Reviews Neurology 6 8 2010 445 453
    • (2010) Nature Reviews Neurology , vol.6 , Issue.8 , pp. 445-453
    • Pal, D.K.1    Pong, A.W.2    Chung, W.K.3
  • 58
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • DOI 10.1038/ng1847, PII NG1847
    • A.L. Price, N.J. Patterson, R.M. Plenge, M.E. Weinblatt, N.A. Shadick, and D. Reich Principal components analysis corrects for stratification in genome-wide association studies Nature Genetics 38 8 2006 904 909 (Pubitemid 44141658)
    • (2006) Nature Genetics , vol.38 , Issue.8 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 59
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • S.M. Purcell, N.R. Wray, J.L. Stone, P.M. Visscher, M.C. O'Donovan, and P.F. Sullivan Common polygenic variation contributes to risk of schizophrenia and bipolar disorder Nature 460 7256 2009 748 752
    • (2009) Nature , vol.460 , Issue.7256 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5    Sullivan, P.F.6
  • 61
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • N. Risch, and K. Merikangas The future of genetic studies of complex human diseases Science 273 5281 1996 1516 1517 (Pubitemid 26301653)
    • (1996) Science , vol.273 , Issue.5281 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 62
    • 84860780495 scopus 로고    scopus 로고
    • De novo mutations revealed by whole-exome sequencing are strongly associated with autism
    • S.J. Sanders, M.T. Murtha, A.R. Gupta, J.D. Murdoch, M.J. Raubeson, and A.J. Willsey De novo mutations revealed by whole-exome sequencing are strongly associated with autism Nature 485 7397 2012 237 241
    • (2012) Nature , vol.485 , Issue.7397 , pp. 237-241
    • Sanders, S.J.1    Murtha, M.T.2    Gupta, A.R.3    Murdoch, J.D.4    Raubeson, M.J.5    Willsey, A.J.6
  • 65
    • 77954158128 scopus 로고    scopus 로고
    • Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene
    • N.L. Sobreira, E.T. Cirulli, D. Avramopoulos, E. Wohler, G.L. Oswald, and E.L. Stevens Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene PLoS Genetics 6 6 2010 e1000991
    • (2010) PLoS Genetics , vol.6 , Issue.6 , pp. 1000991
    • Sobreira, N.L.1    Cirulli, E.T.2    Avramopoulos, D.3    Wohler, E.4    Oswald, G.L.5    Stevens, E.L.6
  • 68
    • 0028980028 scopus 로고
    • A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy
    • O.K. Steinlein, J.C. Mulley, P. Propping, R.H. Wallace, H.A. Phillips, and G.R. Sutherland A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy Nature Genetics 11 2 1995 201 203
    • (1995) Nature Genetics , vol.11 , Issue.2 , pp. 201-203
    • Steinlein, O.K.1    Mulley, J.C.2    Propping, P.3    Wallace, R.H.4    Phillips, H.A.5    Sutherland, G.R.6
  • 69
    • 7944233055 scopus 로고    scopus 로고
    • Genetic association studies in epilepsy: "The truth is out there"
    • DOI 10.1111/j.0013-9580.2004.22904.x
    • N.C. Tan, J.C. Mulley, and S.F. Berkovic Genetic association studies in epilepsy: "The truth is out there" Epilepsia 45 11 2004 1429 1442 (Pubitemid 39470047)
    • (2004) Epilepsia , vol.45 , Issue.11 , pp. 1429-1442
    • Tan, N.C.K.1    Mulley, J.C.2    Berkovic, S.F.3
  • 70
    • 84863556835 scopus 로고    scopus 로고
    • Evolution and functional impact of rare coding variation from deep sequencing of human exomes
    • J.A. Tennessen, A.W. Bigham, T.D. O'Connor, W. Fu, E.E. Kenny, and S. Gravel Evolution and functional impact of rare coding variation from deep sequencing of human exomes Science 337 2012 64 69
    • (2012) Science , vol.337 , pp. 64-69
    • Tennessen, J.A.1    Bigham, A.W.2    O'Connor, T.D.3    Fu, W.4    Kenny, E.E.5    Gravel, S.6
  • 71
    • 79251560652 scopus 로고    scopus 로고
    • Post-mortem review and genetic analysis of sudden unexpected death in epilepsy (SUDEP) cases
    • E. Tu, R.D. Bagnall, J. Duflou, and C. Semsarian Post-mortem review and genetic analysis of sudden unexpected death in epilepsy (SUDEP) cases Brain Pathology 21 2 2011 201 208
    • (2011) Brain Pathology , vol.21 , Issue.2 , pp. 201-208
    • Tu, E.1    Bagnall, R.D.2    Duflou, J.3    Semsarian, C.4
  • 72
    • 80054679391 scopus 로고    scopus 로고
    • Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases
    • E. Tu, L. Waterhouse, J. Duflou, R.D. Bagnall, and C. Semsarian Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases Brain Pathology 21 6 2011 692 698
    • (2011) Brain Pathology , vol.21 , Issue.6 , pp. 692-698
    • Tu, E.1    Waterhouse, L.2    Duflou, J.3    Bagnall, R.D.4    Semsarian, C.5
  • 76
    • 0344738663 scopus 로고    scopus 로고
    • Genetic influences on myoclonic and absence seizures
    • M.R. Winawer, D. Rabinowitz, T.A. Pedley, W.A. Hauser, and R. Ottman Genetic influences on myoclonic and absence seizures Neurology 61 11 2003 1576 1581 (Pubitemid 37505582)
    • (2003) Neurology , vol.61 , Issue.11 , pp. 1576-1581
    • Winawer, M.R.1    Rabinowitz, D.2    Pedley, T.A.3    Hauser, W.A.4    Ottman, R.5


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