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Volumn 365, Issue 11, 2011, Pages 1033-1041

Genomics, health care, and society

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AZATHIOPRINE; CARBAMAZEPINE; CETUXIMAB; CLOPIDOGREL; IRINOTECAN; PANITUMUMAB; PROTRIPTYLINE; TRASTUZUMAB; WARFARIN;

EID: 80052859044     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMra1010517     Document Type: Review
Times cited : (112)

References (73)
  • 2
    • 77954407332 scopus 로고    scopus 로고
    • Genomewide association studies and assessment of the risk of disease
    • Manolio TA. Genomewide association studies and assessment of the risk of disease. N Engl J Med 2010;363:166-76.
    • (2010) N Engl J Med , vol.363 , pp. 166-176
    • Manolio, T.A.1
  • 3
    • 77956044839 scopus 로고    scopus 로고
    • New therapeutic approaches to mendelian disorders
    • Dietz HC. New therapeutic approaches to mendelian disorders. N Engl J Med 2010;363:852-63.
    • (2010) N Engl J Med , vol.363 , pp. 852-863
    • Dietz, H.C.1
  • 4
    • 78649842241 scopus 로고    scopus 로고
    • Genomics, type 2 diabetes, and obesity
    • McCarthy MI. Genomics, type 2 diabetes, and obesity. N Engl J Med 2010;363: 2339-50.
    • (2010) N Engl J Med , vol.363 , pp. 2339-2350
    • McCarthy, M.I.1
  • 6
    • 0035755351 scopus 로고    scopus 로고
    • Integrating genotype and phenotype information: An overview of the PharmGKB project
    • Klein TE, Chang JT, Cho MK, et al. Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenomics J 2001;1:167-70. (Pubitemid 33756654)
    • (2001) Pharmacogenomics Journal , vol.1 , Issue.3 , pp. 167-170
    • Klein, T.E.1
  • 9
    • 77954788338 scopus 로고    scopus 로고
    • Patients' attitudes to informed consent for genomic research with donated samples
    • Valle-Mansilla JI, Ruiz-Canela M, Sulmasy DP. Patients' attitudes to informed consent for genomic research with donated samples. Cancer Invest 2010;28:726-34.
    • (2010) Cancer Invest , vol.28 , pp. 726-734
    • Valle-Mansilla, J.I.1    Ruiz-Canela, M.2    Sulmasy, D.P.3
  • 10
    • 4644342620 scopus 로고    scopus 로고
    • Untapped potential: IRB guidance for the ethical research use of stored biological materials
    • DOI 10.2307/3563696
    • Wolf LE, Lo B. Untapped potential: IRB guidance for the ethical research use of stored biological materials. IRB 2004; 26:1-8. (Pubitemid 43362256)
    • (2004) IRB Ethics and Human Research , vol.26 , Issue.4 , pp. 1-8
    • Wolf, L.E.1    Lo, B.2
  • 11
    • 40849139474 scopus 로고    scopus 로고
    • Ethical, legal, and social implications of biobanks for genetics research
    • Haga SB, Beskow LM. Ethical, legal, and social implications of biobanks for genetics research. Adv Genet 2008;60:505-44.
    • (2008) Adv Genet , vol.60 , pp. 505-544
    • Haga, S.B.1    Beskow, L.M.2
  • 14
    • 3042849144 scopus 로고    scopus 로고
    • Genomic research and human subject privacy
    • DOI 10.1126/science.1095019
    • Lin Z, Owen AB, Altman RB. Genomic research and human subject privacy. Science 2004;305:183. (Pubitemid 38886715)
    • (2004) Science , vol.305 , Issue.5681 , pp. 183
    • Lin, Z.1    Owen, A.B.2    Altman, R.B.3
  • 15
    • 50849101381 scopus 로고    scopus 로고
    • Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays
    • Homer N, Szelinger S, Redman M, et al. Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays. PLoS Genet 2008;4(8): e1000167.
    • (2008) PLoS Genet , vol.4 , Issue.8
    • Homer, N.1    Szelinger, S.2    Redman, M.3
  • 18
    • 4143137470 scopus 로고    scopus 로고
    • Certificates of confidentiality in research: Rationale and usage
    • DOI 10.1089/gte.2004.8.214
    • Cooper ZN, Nelson RM, Ross LF. Certificates of confidentiality in research: rationale and usage. Genet Test 2004;8:214-20. (Pubitemid 39096767)
    • (2004) Genetic Testing , vol.8 , Issue.2 , pp. 214-220
    • Cooper, Z.N.1    Nelson, R.M.2    Ross, L.F.3
  • 19
  • 20
    • 80052847587 scopus 로고    scopus 로고
    • Reforming the regulations governing research with human subjects
    • DOI: 10.1056/NEJMsb1106942
    • Emanuel EJ, Menikoff J. Reforming the regulations governing research with human subjects. N Engl J Med 2011. DOI: 10.1056/NEJMsb1106942.
    • (2011) N Engl J Med
    • Emanuel, E.J.1    Menikoff, J.2
  • 21
    • 80052857705 scopus 로고    scopus 로고
    • Human subjects research protections: Enhancing protections for research subjects and reducing burden, delay, and ambiguity for investigators
    • Human subjects research protections: enhancing protections for research subjects and reducing burden, delay, and ambiguity for investigators. Fed Regist 2011; 76(143):44512-31.
    • (2011) Fed Regist , vol.76 , Issue.143 , pp. 44512-44531
  • 22
    • 38449089111 scopus 로고    scopus 로고
    • The uneasy ethical and legal underpinnings of large-scale genomic biobanks
    • Greely HT. The uneasy ethical and legal underpinnings of large-scale genomic biobanks. Annu Rev Genomics Hum Genet 2007;8:343-64.
    • (2007) Annu Rev Genomics Hum Genet , vol.8 , pp. 343-364
    • Greely, H.T.1
  • 23
    • 29944440965 scopus 로고    scopus 로고
    • Implications of disclosing individual results of clinical research
    • Clayton EW, Ross LF. Implications of disclosing individual results of clinical research. JAMA 2006;295:37-8.
    • (2006) JAMA , vol.295 , pp. 37-38
    • Clayton, E.W.1    Ross, L.F.2
  • 24
    • 44449162023 scopus 로고    scopus 로고
    • Communicating the results of clinical research to participants: Attitudes, practices, and future directions
    • Shalowitz DI, Miller FG. Communicating the results of clinical research to participants: attitudes, practices, and future directions. PLoS Med 2008;5(5):e91.
    • (2008) PLoS Med , vol.5 , Issue.5
    • Shalowitz, D.I.1    Miller, F.G.2
  • 25
    • 57449115536 scopus 로고    scopus 로고
    • Subjects matter: A survey of public opinions about a large genetic cohort study
    • Kaufman D, Murphy J, Scott J, Hudson K. Subjects matter: a survey of public opinions about a large genetic cohort study. Genet Med 2008;10:831-9.
    • (2008) Genet Med , vol.10 , pp. 831-839
    • Kaufman, D.1    Murphy, J.2    Scott, J.3    Hudson, K.4
  • 26
    • 60849120468 scopus 로고    scopus 로고
    • Providing research results to participants: Attitudes and needs of adolescents and parents of children with cancer
    • Fernandez CV, Gao J, Strahlendorf C, et al. Providing research results to participants: attitudes and needs of adolescents and parents of children with cancer. J Clin Oncol 2009;27:878-83.
    • (2009) J Clin Oncol , vol.27 , pp. 878-883
    • Fernandez, C.V.1    Gao, J.2    Strahlendorf, C.3
  • 29
    • 77957730126 scopus 로고    scopus 로고
    • News release of the National Institutes of Health, Bethesda, MD, March 18
    • NIH announces Genetic Testing Registry. News release of the National Institutes of Health, Bethesda, MD, March 18, 2010.
    • (2010) NIH Announces Genetic Testing Registry
  • 31
    • 84877634779 scopus 로고    scopus 로고
    • National Center for Biotechnology Information. Genetic Testing Registry. (http:// www.ncbi.nlm.nih.gov/gtr/.)
    • Genetic Testing Registry
  • 32
    • 77954827460 scopus 로고    scopus 로고
    • The path to personalized medicine
    • Erratum, N Engl J Med 2010;363:1092
    • Hamburg MA, Collins FS. The path to personalized medicine. N Engl J Med 2010;363:301-4. [Erratum, N Engl J Med 2010;363:1092.]
    • (2010) N Engl J Med , vol.363 , pp. 301-304
    • Hamburg, M.A.1    Collins, F.S.2
  • 33
    • 0037006623 scopus 로고    scopus 로고
    • Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
    • Mallal S, Nolan D, Witt C, et al. Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 2002;359:727-32.
    • (2002) Lancet , vol.359 , pp. 727-732
    • Mallal, S.1    Nolan, D.2    Witt, C.3
  • 38
    • 34047248571 scopus 로고    scopus 로고
    • Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
    • DOI 10.1158/0008-5472.CAN-06-4158
    • Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, et al. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res 2007;67:2643-8. (Pubitemid 46548951)
    • (2007) Cancer Research , vol.67 , Issue.6 , pp. 2643-2648
    • Benvenuti, S.1    Sartore-Bianchi, A.2    Di, N.F.3    Zanon, C.4    Moroni, M.5    Veronese, S.6    Siena, S.7    Bardelli, A.8
  • 39
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • Flaherty KT, Puzanov I, Kim KB, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 2010; 363:809-19.
    • (2010) N Engl J Med , vol.363 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 41
    • 85031223604 scopus 로고    scopus 로고
    • Florham Park, NJ: Odyssey Pharmaceuticals, (package insert)
    • Protriptyline. Florham Park, NJ: Odyssey Pharmaceuticals, 2000 (package insert).
    • (2000) Protriptyline
  • 42
    • 80052824909 scopus 로고    scopus 로고
    • New York: Bristol-Myers Squibb, (package insert)
    • Coumadin. New York: Bristol-Myers Squibb, 2010 (package insert).
    • (2010) Coumadin
  • 43
    • 80052836121 scopus 로고    scopus 로고
    • Philadelphia: GlaxoSmithKline, (package insert)
    • Ziagen. Philadelphia: GlaxoSmithKline, 2010 (package insert).
    • (2010) Ziagen
  • 44
    • 85031213002 scopus 로고    scopus 로고
    • San Diego, CA: Prometheus Laboratories, (package insert)
    • Imuran. San Diego, CA: Prometheus Laboratories, 2008 (package insert).
    • (2008) Imuran
  • 45
    • 85031226184 scopus 로고    scopus 로고
    • Basel, Switzerland: Novartis, (package insert)
    • Tegretol. Basel, Switzerland: Novartis, 2009 (package insert).
    • (2009) Tegretol
  • 46
    • 80052829086 scopus 로고    scopus 로고
    • New York: Bristol-Myers Squibb, (package insert)
    • Erbitux. New York: Bristol-Myers Squibb, 2009 (package insert).
    • (2009) Erbitux
  • 47
    • 80052839758 scopus 로고    scopus 로고
    • New York: Bristol-Myers Squibb, (package insert)
    • Plavix. New York: Bristol-Myers Squibb, 2010 (package insert).
    • (2010) Plavix
  • 48
    • 79956210982 scopus 로고    scopus 로고
    • New York: Pfizer, (package insert)
    • Camptosar. New York: Pfizer, 2010 (package insert).
    • (2010) Camptosar
  • 49
    • 81055153182 scopus 로고    scopus 로고
    • Thousand Oaks, CA: Amgen, (package insert)
    • Vectibix. Thousand Oaks, CA: Amgen, 2009 (package insert).
    • (2009) Vectibix
  • 50
    • 85031211861 scopus 로고    scopus 로고
    • South San Francisco, CA: Genentech, (package insert)
    • Herceptin. South San Francisco, CA: Genentech, 2010 (package insert).
    • (2010) Herceptin
  • 52
    • 52049118113 scopus 로고    scopus 로고
    • Confidentiality, privacy, and security of genetic and genomic test information in electronic health records: Points to consider
    • McGuire AL, Fisher R, Cusenza P, et al. Confidentiality, privacy, and security of genetic and genomic test information in electronic health records: points to consider. Genet Med 2008;10:495-9.
    • (2008) Genet Med , vol.10 , pp. 495-499
    • McGuire, A.L.1    Fisher, R.2    Cusenza, P.3
  • 53
    • 0000027394 scopus 로고    scopus 로고
    • Standards for privacy of individually identifiable health information: Final rule
    • Standards for privacy of individually identifiable health information: final rule. Fed Regist 2000;65(250):82661.
    • (2000) Fed Regist , vol.65 , Issue.250 , pp. 82661
  • 55
    • 56049112782 scopus 로고    scopus 로고
    • Genomic anonymity: Have we already lost it?
    • Greenbaum D, Du J, Gerstein M. Genomic anonymity: have we already lost it? Am J Bioeth 2008;8:71-4.
    • (2008) Am J Bioeth , vol.8 , pp. 71-74
    • Greenbaum, D.1    Du, J.2    Gerstein, M.3
  • 56
    • 77949806213 scopus 로고    scopus 로고
    • HIPAA administrative simplification: Standards for privacy of individually identifiable health information
    • HIPAA administrative simplification: standards for privacy of individually identifiable health information. Fed Regist 2009;74(193):51698-710.
    • (2009) Fed Regist , vol.74 , Issue.193 , pp. 51698-51710
  • 57
    • 80052849242 scopus 로고    scopus 로고
    • Senate backs privacy for genetic data: The landmark bill would shield people from insurance and job discrimination based on test results
    • April 25
    • Alonso-Zaldivar R. Senate backs privacy for genetic data: the landmark bill would shield people from insurance and job discrimination based on test results. Los Angeles Times. April 25, 2008.
    • (2008) Los Angeles Times
    • Alonso-Zaldivar, R.1
  • 60
  • 61
    • 53049083346 scopus 로고    scopus 로고
    • Civilian and military genetics: Nondiscrimination policy in a post-GINA world
    • Baruch S, Hudson K. Civilian and military genetics: nondiscrimination policy in a post-GINA world. Am J Hum Genet 2008;83:435-44.
    • (2008) Am J Hum Genet , vol.83 , pp. 435-444
    • Baruch, S.1    Hudson, K.2
  • 62
    • 77956533115 scopus 로고    scopus 로고
    • Screening student athletes for sickle cell trait - A social and clinical experiment
    • Bonham VL, Dover GJ, Brody LC. Screening student athletes for sickle cell trait - a social and clinical experiment. N Engl J Med 2010;363:997-9.
    • (2010) N Engl J Med , vol.363 , pp. 997-999
    • Bonham, V.L.1    Dover, G.J.2    Brody, L.C.3
  • 64
  • 66
    • 12344294195 scopus 로고    scopus 로고
    • Selective arrests, an ever-expanding DNA forensic database, and the specter of an early-twenty-first-century equivalent of phrenology
    • Lazer D, ed. Cambridge, MA: MIT Press
    • Duster T. Selective arrests, an ever-expanding DNA forensic database, and the specter of an early-twenty-first-century equivalent of phrenology. In: Lazer D, ed. DNA and the criminal justice system: the technology of justice. Cambridge, MA: MIT Press, 2004:315-34.
    • (2004) DNA and the Criminal Justice System: The Technology of Justice , pp. 315-334
    • Duster, T.1
  • 67
    • 85031233715 scopus 로고    scopus 로고
    • Diamond v. Chakrabarty, 447 U.S. 303 (1980)
    • Diamond v. Chakrabarty, 447 U.S. 303 (1980).
  • 71
    • 77951454005 scopus 로고    scopus 로고
    • Myriad genetics: In the eye of the policy storm
    • Gold ER, Corbone J. Myriad genetics: in the eye of the policy storm. Genet Med 2010;12:Suppl:S39-S70.
    • (2010) Genet Med , vol.12 , Issue.SUPPL.
    • Gold, E.R.1    Corbone, J.2
  • 72
    • 85031225098 scopus 로고    scopus 로고
    • The Association for Molecular Pathology v. United States Patent and Trademark Office, No. 09 Civ. 4515 (2009)
    • The Association for Molecular Pathology v. United States Patent and Trademark Office, No. 09 Civ. 4515 (2009).
  • 73
    • 80052838656 scopus 로고    scopus 로고
    • Department of Justice. The Association for Molecular Pathology v. United States Patent and Trademark Office, No. 2010-1406
    • Department of Justice. Brief for the United States as amicus curiae in support of neither party. The Association for Molecular Pathology v. United States Patent and Trademark Office, No. 2010-1406 (2010).
    • (2010) Brief for the United States As Amicus Curiae in Support of Neither Party


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.