Preparative enantioseparation of β-blocker drugs by counter-current chromatography using dialkyl l-tartrate as chiral selector based on borate coordination complex

Journal of Chromatography A

Volumn 1263, Issue , 2012, Pages 74-83

  Tong, Shengqiang ^a   Zheng, Ye ^a   Yan, Jizhong ^a   Guan, Yi Xin ^b   Wu, Chunyan ^a   Lei, Wenyu ^a  

^a ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Blocker drugs; Borate coordination complex; Counter current chromatography; Di n hexyl l tartrate; PH zone refining mode; Preparative enantioseparation

Indexed keywords

COORDINATION COMPLEX; COUNTERCURRENT CHROMATOGRAPHY; DI-N-HEXYL L-TARTRATE; ENANTIOSEPARATIONS; PH-ZONE-REFINING MODE;

CHIRALITY; COORDINATION REACTIONS; ENANTIOMERS; INORGANIC ACIDS; ORGANIC SOLVENTS; REFINING;

CHROMATOGRAPHY;

ALPRENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BORIC ACID; DIALKYL TARTRATE; PINDOLOL; PROPRANOLOL; TARTARIC ACID; UNCLASSIFIED DRUG;

ARTICLE; COUNTER CURRENT CHROMATOGRAPHY; DRUG PURITY; ENANTIOMER; ENANTIOSEPARATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; PH; PRIORITY JOURNAL; RACEMIC MIXTURE; SEPARATION TECHNIQUE;

ADRENERGIC BETA-ANTAGONISTS; BORATES; COUNTERCURRENT DISTRIBUTION; STEREOISOMERISM; TARTRATES;

EID: 84867459436     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.09.023     Document Type: Article

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