Enantioseparation of phenylsuccinic acid by high speed counter-current chromatography using hydroxypropyl-β-cyclodextrin as chiral selector

Journal of Chromatography A

Volumn 1218, Issue 33, 2011, Pages 5602-5608

  Tong, Shengqiang ^a,b   Yan, Jizhong ^b   Guan, Yi Xin ^a   Lu, Youming ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Chiral separation; High speed counter current chromatography; Hydroxypropyl cyclodextrin; Phenylsuccinic acid

Indexed keywords

ANALYTICAL INSTRUMENT; AQUEOUS PHASE; CHIRAL SELECTOR; CHIRAL SEPARATIONS; COMPLEX FORMATION CONSTANTS; ENANTIOMERIC EXCESS; ENANTIOSEPARATIONS; HIGH-SPEED COUNTER-CURRENT CHROMATOGRAPHY; INCLUSION COMPLEX; INFLUENCE FACTORS; PEAK RESOLUTION; PH VALUE; PHENYLSUCCINIC ACID; PHOSPHATE BUFFER SOLUTIONS; SEPARATION CONDITION; TARGET COMPOUND; THERMODYNAMIC PARAMETER; TWO-PHASE SOLVENT SYSTEM;

CHIRALITY; ETHERS; HEXANE; ORGANIC SOLVENTS; PHASE SEPARATION;

CHROMATOGRAPHY;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; PHENYLSUCCINIC ACID; SOLVENT; SUCCINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHIRAL CHROMATOGRAPHY; CHIRALITY; COMPLEX FORMATION; COUNTER CURRENT CHROMATOGRAPHY; ELUTION; ENANTIOSELECTIVITY; ENTHALPY; ENTROPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; PARTITION COEFFICIENT; PH; PRIORITY JOURNAL; SEPARATION TECHNIQUE; TEMPERATURE;

ADSORPTION; BETA-CYCLODEXTRINS; COUNTERCURRENT DISTRIBUTION; STEREOISOMERISM; SUCCINATES;

EID: 79960699712     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.06.023     Document Type: Article

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