메뉴 건너뛰기




Volumn 84, Issue 1, 2012, Pages 22-31

New insights into the management of renal cell cancer

Author keywords

HIF; mTOR; Renal cell carcinoma; Targeted therapy; Therapeutic response; Treatment resistance; VEGF; VHL

Indexed keywords

1 (1 CYANO 1 METHYLETHYL) 3 METHYL 8 (3 QUINOLINYL)IMIDAZO[4,5 C]QUINOLIN 2(1H,3H) ONE; ALPHA INTERFERON; AXITINIB; BEVACIZUMAB; CABOZANTINIB; DOVITINIB; EVEROLIMUS; FIBROBLAST GROWTH FACTOR; FORETINIB; GDC 0980; IMATINIB; INTERFERON; INTERLEUKIN 2; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MONOCLONAL ANTIBODY; MOTESANIB; PAZOPANIB; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PLACEBO; PROTEIN TYROSINE KINASE INHIBITOR; RAPAMYCIN; RILOTUMUMAB; SCATTER FACTOR RECEPTOR; SORAFENIB; SUNITINIB; TEMSIROLIMUS; TIVOZANIB; UNCLASSIFIED DRUG; VASCULOTROPIN INHIBITOR;

EID: 84867451301     PISSN: 00302414     EISSN: 14230232     Source Type: Journal    
DOI: 10.1159/000342962     Document Type: Review
Times cited : (16)

References (68)
  • 3
    • 77952263737 scopus 로고    scopus 로고
    • The genetic basis of kidney cancer: A metabolic disease
    • Linehan WM, Srinivasan R, Schmidt LS: The genetic basis of kidney cancer: A metabolic disease. Nat Rev Urol 2010; 7: 277-285
    • (2010) Nat Rev Urol , vol.7 , pp. 277-285
    • Linehan, W.M.1    Srinivasan, R.2    Schmidt, L.S.3
  • 4
    • 42649145828 scopus 로고    scopus 로고
    • Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): A literature review
    • Gupta K, Miller JD, Li JZ, Russell MW, Charbonneau C: Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): A literature review. Cancer Treat Rev 2008; 4: 193-205
    • (2008) Cancer Treat Rev , vol.4 , pp. 193-205
    • Gupta, K.1    Miller, J.D.2    Li, J.Z.3    Russell, M.W.4    Charbonneau, C.5
  • 6
    • 33846879810 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma
    • Kaelin WG: The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma. Clin Cancer Res 2007; 13: 680s-684s.
    • (2007) Clin Cancer Res , vol.13
    • Kaelin, W.G.1
  • 10
    • 79959653996 scopus 로고    scopus 로고
    • SWI/SNF nucleosome remodellers and cancer
    • Wilson BG, Roberts CWM: SWI/SNF nucleosome remodellers and cancer. Nat Rev Cancer 2011; 11: 481-492
    • (2011) Nat Rev Cancer , vol.11 , pp. 481-492
    • Wilson, B.G.1    Roberts, C.W.M.2
  • 15
    • 75349102521 scopus 로고    scopus 로고
    • Bevacizumab, sorafenib tosylate, sunitinib and temsirolimus for renal cell carcinoma: A systematic review and economic evaluation
    • Thompson Coon J, Hoyle M, Green C, Liu Z, Welch K, Moxham T, Stein K: Bevacizumab, sorafenib tosylate, sunitinib and temsirolimus for renal cell carcinoma: A systematic review and economic evaluation. Health Technol Assess 2010; 14: 1-208
    • (2010) Health Technol Assess , vol.14 , pp. 1-208
    • Thompson Coon, J.1    Hoyle, M.2    Green, C.3    Liu, Z.4    Welch, K.5    Moxham, T.6    Stein, K.7
  • 16
    • 41549092232 scopus 로고    scopus 로고
    • Economic evaluation of sunitinib malate in second-line treatment of metastatic renal cell carcinoma in Finland
    • DOI 10.1016/j.clinthera.2008.02.013, PII S0149291808000969
    • Purmonen T, Martikainen JA, Soini EJO, Kataja V, Vuorinen RL, Kellokumpu-Lehtinen PL: Economic evaluation of sunitinib malate in second-line treatment of metastatic renal cell carcinoma in Finland. Clin Ther 2008; 30: 382-392 (Pubitemid 351474383)
    • (2008) Clinical Therapeutics , vol.30 , Issue.2 , pp. 382-392
    • Purmonen, T.1    Martikainen, J.A.2    Soini, E.J.O.3    Kataja, V.4    Vuorinen, R.-L.5    Kellokumpu-Lehtinen, P.-L.6
  • 17
    • 77956373891 scopus 로고    scopus 로고
    • How do cost-effectiveness analyses inform reimbursement decisions for oncology medicines in Canada? The example of sunitinib for first-line treatment of metastatic renal cell carcinoma
    • Chabot I, Rocchi A: How do cost-effectiveness analyses inform reimbursement decisions for oncology medicines in Canada? The example of sunitinib for first-line treatment of metastatic renal cell carcinoma. Value ealth 2010; 13: 837-845
    • (2010) Value ealth , vol.13 , pp. 837-845
    • Chabot, I.1    Rocchi, A.2
  • 21
    • 77952300540 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
    • Escudier B, Bellmunt J, Negrier S, Bajetta E, Melichar B, Bracarda S, Ravaud A, Golding S, Jethwa S, Sneller V: Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival. J Clin Oncol 2010; 28: 2144-2150
    • (2010) J Clin Oncol , vol.28 , pp. 2144-2150
    • Escudier, B.1    Bellmunt, J.2    Negrier, S.3    Bajetta, E.4    Melichar, B.5    Bracarda, S.6    Ravaud, A.7    Golding, S.8    Jethwa, S.9    Sneller, V.10
  • 23
    • 84865506371 scopus 로고    scopus 로고
    • Patient preference between pazopanib (Paz) and sunitinib (Sun): Results of a randomized double-blind, placebo-controlled, crossover study in patients with metastatic renal cell carcinoma (mRCC) - PISCES study, NCT 01064310
    • suppl; abstr CRA4502
    • Escudier BJ, Porta C, Bono P, De Giorgi U, Parikh O, Hawkins RE, Sevin E, Negrier S, Khan S, McCann L, Mehmud F, Cella D: Patient preference between pazopanib (Paz) and sunitinib (Sun): Results of a randomized double-blind, placebo-controlled, crossover study in patients with metastatic renal cell carcinoma (mRCC) - PISCES study, NCT 01064310. J Clin Oncol 2012; 30(suppl; abstr CRA4502).
    • (2012) J Clin Oncol , pp. 30
    • Escudier, B.J.1    Porta, C.2    Bono, P.3    De Giorgi, U.4    Parikh, O.5    Hawkins, R.E.6    Sevin, E.7    Negrier, S.8    Khan, S.9    McCann, L.10    Mehmud, F.11    Cella, D.12
  • 25
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • Bergers G, Hanahan D: Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 2008; 8: 592-603
    • (2008) Nat Rev Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 29
    • 84865473303 scopus 로고    scopus 로고
    • Axitinib for first-line metastatic renal cell carcinoma (mRCC): Overall efficacy and pharmacokinetic (PK) analyses from a randomized phase II study
    • suppl; abstr 4503
    • Rini BI, Grünwald V, Fishman M, Melichar B, Ueda T, Karlov P, Bair A, Chen Y, Kim S, Jonasch E: Axitinib for first-line metastatic renal cell carcinoma (mRCC): Overall efficacy and pharmacokinetic (PK) analyses from a randomized phase II study. J Clin Oncol 2012; 30(suppl; abstr 4503).
    • (2012) J Clin Oncol , pp. 30
    • Rini, B.I.1    Grünwald, V.2    Fishman, M.3    Melichar, B.4    Ueda, T.5    Karlov, P.6    Bair, A.7    Chen, Y.8    Kim, S.9    Jonasch, E.10
  • 32
    • 26644471951 scopus 로고    scopus 로고
    • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
    • DOI 10.1016/j.ccr.2005.09.005, PII S1535610805002989
    • Casanovas O, Hicklin DJ, Bergers G, Hanahan D: Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in latestage pancreatic islet tumors. Cancer Cell 2005; 8: 299-309 (Pubitemid 41443415)
    • (2005) Cancer Cell , vol.8 , Issue.4 , pp. 299-309
    • Casanovas, O.1    Hicklin, D.J.2    Bergers, G.3    Hanahan, D.4
  • 44
    • 71049154727 scopus 로고    scopus 로고
    • A phase II study of two dosing regimens of GSK1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in patients (pts) with papillary renal carcinoma (PRC)
    • abstr 5103
    • Srinivasan R, Linehan W, Vaishampayan U, Logan T, Shankar SM, Sherman LJ, Liu Y, Choueiri TK: A phase II study of two dosing regimens of GSK1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in patients (pts) with papillary renal carcinoma (PRC). In J Clin Oncol 2009; 27(suppl; abstr 5103).
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • Srinivasan, R.1    Linehan, W.2    Vaishampayan, U.3    Logan, T.4    Shankar, S.M.5    Sherman, L.J.6    Liu, Y.7    Choueiri, T.K.8
  • 46
    • 7944235758 scopus 로고    scopus 로고
    • Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
    • DOI 10.1038/ncb1183
    • Jacinto E, Loewith R, Schmidt A, Lin S, Rüegg MA, Hall A, Hall MN: Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol 2004; 6: 1122-1128 (Pubitemid 39468014)
    • (2004) Nature Cell Biology , vol.6 , Issue.11 , pp. 1122-1128
    • Jacinto, E.1    Loewith, R.2    Schmidt, A.3    Lin, S.4    Ruegg, M.A.5    Hall, A.6    Hall, M.N.7
  • 47
    • 38049187096 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/ Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: Rationale for therapeutic inhibition of both pathways
    • Tamburini J, Chapuis N, Bardet V, Park S, Sujobert P, Willems L, Ifrah N, Dreyfus F, Mayeux P, Lacombe C, Bouscary D: Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/ Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: Rationale for therapeutic inhibition of both pathways. Blood 2008; 111: 379- 382
    • (2008) Blood , vol.111 , pp. 379-382
    • Tamburini, J.1    Chapuis, N.2    Bardet, V.3    Park, S.4    Sujobert, P.5    Willems, L.6    Ifrah, N.7    Dreyfus, F.8    Mayeux, P.9    Lacombe, C.10    Bouscary, D.11
  • 48
    • 77950516104 scopus 로고    scopus 로고
    • MTOR signaling and drug development in cancer
    • Dancey J: MTOR signaling and drug development in cancer. Nat Rev Clin Oncol 2010; 7: 209-219
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 209-219
    • Dancey, J.1
  • 49
    • 79957530990 scopus 로고    scopus 로고
    • Mechanisms of mTOR inhibitor resistance in cancer therapy
    • Carew JS, Kelly KR, Nawrocki ST: Mechanisms of mTOR inhibitor resistance in cancer therapy. Targ Oncol 2011; 6: 17-27
    • (2011) Targ Oncol , vol.6 , pp. 17-27
    • Carew, J.S.1    Kelly, K.R.2    Nawrocki, S.T.3
  • 52
    • 1542327748 scopus 로고    scopus 로고
    • Cytoreductive nephrectomy in patients with metastatic renal cancer: A combined analysis
    • DOI 10.1097/01.ju.0000110610.61545.ae
    • Flanigan RC, Mickisch G, Sylvester R, Tangen C, Van Poppel H, Crawford ED: Cytoreductive nephrectomy in patients with metastatic renal cancer: A combined analysis. J Urol 2004; 171: 1071-1076 (Pubitemid 38327529)
    • (2004) Journal of Urology , vol.171 , Issue.3 , pp. 1071-1076
    • Flanigan, R.C.1    Mickisch, G.2    Sylvester, R.3    Tangen, C.4    Van Poppel, H.5    Crawford, E.D.6
  • 53
    • 77954326508 scopus 로고    scopus 로고
    • On behalf of the ESMO guidelines working group: Renal cell carcinoma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
    • Escudier B, Kataja V, on behalf of the ESMO Guidelines Working Group: Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010; 21:v137-v139
    • (2010) Ann Oncol , vol.21
    • Escudier, B.1    Kataja, V.2
  • 56
    • 79953848961 scopus 로고    scopus 로고
    • Survival after complete surgical resection of multiple metastases from renal cell carcinoma
    • Alt AL, Boorjian SA, Lohse CM, Costello BA, Leibovich BC, Blute ML: Survival after complete surgical resection of multiple metastases from renal cell carcinoma. Cancer 2011; 117: 2873-2882
    • (2011) Cancer , vol.117 , pp. 2873-2882
    • Alt, A.L.1    Boorjian, S.A.2    Lohse, C.M.3    Costello, B.A.4    Leibovich, B.C.5    Blute, M.L.6
  • 61
    • 78650387508 scopus 로고    scopus 로고
    • Pazopanib in renal cell carcinoma
    • Ward JE, Stadler WM: Pazopanib in renal cell carcinoma. Clin Cancer Res 2010; 16: 5923-5927
    • (2010) Clin Cancer Res , vol.16 , pp. 5923-5927
    • Ward, J.E.1    Stadler, W.M.2
  • 64
    • 84870813019 scopus 로고    scopus 로고
    • Determination of a new RECIST threshold using everolimus treatment in metastatic renal cell carcinoma: Evaluation from the RECORD-1 study
    • suppl; abstr 4147
    • Thiam R, Cuenod C, Fournier L, Lamuraglia M, Medioni J, Barascout B, Scotté F, Fabre- Guillevin E, Oudard S: Determination of a new RECIST threshold using everolimus treatment in metastatic renal cell carcinoma: Evaluation from the RECORD-1 study. Ann Oncol 2010; 21(suppl; abstr 4147).
    • (2010) Ann Oncol , vol.21
    • Thiam, R.1    Cuenod, C.2    Fournier, L.3    Lamuraglia, M.4    Medioni, J.5    Barascout, B.6    Scotté, F.7    Fabre- Guillevin, E.8    Oudard, S.9
  • 68
    • 33748976883 scopus 로고    scopus 로고
    • To predict progression-free survival and overall survival in metastatic renal cancer treated with sorafenib: Pilot study using dynamic contrast-enhanced Doppler ultrasound
    • DOI 10.1016/j.ejca.2006.04.023, PII S0959804906006071
    • Lamuraglia M, Escudier B, Chami L, Schwartz B, Leclère J, Roche A, Lassau N: To predict progression-free survival and overall survival in metastatic renal cancer treated with sorafenib: Pilot study using dynamic contrast-enhanced Doppler ultrasound. Eur J Cancer 2006; 42: 2472-2479 (Pubitemid 44442955)
    • (2006) European Journal of Cancer , vol.42 , Issue.15 , pp. 2472-2479
    • Lamuraglia, M.1    Escudier, B.2    Chami, L.3    Schwartz, B.4    Leclere, J.5    Roche, A.6    Lassau, N.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.