Role of UDP-N-acetylglucosamine (GlcNAc) and O-GlcNacylation of hyaluronan synthase 2 in the control of chondroitin sulfate and hyaluronan synthesis

Journal of Biological Chemistry

Volumn 287, Issue 42, 2012, Pages 35544-35555

  Vigetti, Davide ^a   Deleonibus, Sara ^a   Moretto, Paola ^a   Karousou, Eugenia ^a   Viola, Manuela ^a   Bartolini, Barbara ^a   Hascall, Vincent C ^b   Tammi, Markku ^c   De Luca, Giancarlo ^a   Passi, Alberto ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AORTIC SMOOTH MUSCLE CELLS; CELL BEHAVIORS; CELL DEDIFFERENTIATION; CHONDROITIN SULFATES; GLYCOSAMINOGLYCANS; HUMAN AORTIC SMOOTH MUSCLE CELLS; HYALURONAN; HYALURONAN SYNTHESIS; MICROENVIRONMENTS; N-ACETYLGLUCOSAMINE; O-LINKED; PROTEIN GLYCOSYLATION; SYNTHASES; TURNOVER RATE; UDP-GLUCURONIC ACID; VASCULAR PATHOLOGY;

ADENOSINETRIPHOSPHATE; AMINO ACIDS; CELL MEMBRANES; MUSCLE;

PROTEINS;

CHONDROITIN SULFATE; HYALURONAN SYNTHASE 2; HYALURONIC ACID; HYALURONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE;

ACYLATION; ARTICLE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; CRYSTALLOGRAPHY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN GLYCOSYLATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY;

AMINO ACID SUBSTITUTION; AORTA; CELL LINE; CHONDROITIN SULFATES; DIABETIC ANGIOPATHIES; GLUCURONOSYLTRANSFERASE; GLYCOSYLATION; HUMANS; HYALURONIC ACID; MUSCLE PROTEINS; MUSCLE, SMOOTH, VASCULAR; MUTATION, MISSENSE; URIDINE DIPHOSPHATE N-ACETYLGLUCOSAMINE;

EID: 84867432610     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.402347     Document Type: Article

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