-
1
-
-
70849120946
-
Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease
-
doi:10.1210/er.2008-0047
-
Belfiore A, Frasca F, Pandini G, Sciacca L & Vigneri R 2009 Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease. Endocrine Reviews 30 586-623. (doi:10.1210/er.2008-0047)
-
(2009)
Endocrine Reviews
, vol.30
, pp. 586-623
-
-
Belfiore, A.1
Frasca, F.2
Pandini, G.3
Sciacca, L.4
Vigneri, R.5
-
2
-
-
0031918749
-
The long-acting human insulin analog hoe-901 - Characteristics of insulin signaling in comparison to asp(b10) and regular insulin
-
Berti L, Kellerer M, Bossenmaier B, Seffer E, Seipke G & Haring HU 1998 The long-acting human insulin analog hoe-901 - characteristics of insulin signaling in comparison to asp(b10) and regular insulin. Hormone and Metabolic Research 30 123-129.
-
(1998)
Hormone and Metabolic Research
, vol.30
, pp. 123-129
-
-
Berti, L.1
Kellerer, M.2
Bossenmaier, B.3
Seffer, E.4
Seipke, G.5
Haring, H.U.6
-
3
-
-
0035002183
-
Insulin signalling
-
Bevan P 2001 Insulin signalling. Journal of Cell Science 114 1429-1430.
-
(2001)
Journal of Cell Science
, vol.114
, pp. 1429-1430
-
-
Bevan, P.1
-
4
-
-
0021345618
-
Insulin's structure as a modified and monomeric molecule
-
doi:10.1002/bip.360230302
-
Bi RC, Dauter Z, Dodson E, Dodson G, Giordano F & Reynolds C 1984 Insulin's structure as a modified and monomeric molecule. Biopolymers 23 391-395. (doi:10.1002/bip.360230302)
-
(1984)
Biopolymers
, vol.23
, pp. 391-395
-
-
Bi, R.C.1
Dauter, Z.2
Dodson, E.3
Dodson, G.4
Giordano, F.5
Reynolds, C.6
-
5
-
-
0030207118
-
Signaling via the insulin-like growth factor-I receptor: Does it differ from insulin receptor signaling?
-
doi:10.1016/1359-6101(96)00015-9
-
Blakesley VA, Scrimgeour A, Esposito D & Le Roith D 1996 Signaling via the insulin-like growth factor-I receptor: does it differ from insulin receptor signaling? Cytokine & Growth Factor Reviews 7 153-159. (doi:10.1016/1359-6101(96)00015-9)
-
(1996)
Cytokine & Growth Factor Reviews
, vol.7
, pp. 153-159
-
-
Blakesley, V.A.1
Scrimgeour, A.2
Esposito, D.3
Le Roith, D.4
-
6
-
-
77952760202
-
Insulin and insulin-like growth factor-1 receptors act as ligand-specific amplitude modulators of a common pathway regulating gene transcription
-
doi:10.1074/jbc.M110.118620
-
Boucher J, Tseng YH & Kahn CR 2010 Insulin and insulin-like growth factor-1 receptors act as ligand-specific amplitude modulators of a common pathway regulating gene transcription. Journal of Biological Chemistry 285 17235-17245. (doi:10.1074/jbc.M110.118620)
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 17235-17245
-
-
Boucher, J.1
Tseng, Y.H.2
Kahn, C.R.3
-
7
-
-
84867434810
-
-
Doctoral Thesis 2009. Erasmus MC, University Medical Center Rotterdam, The Netherlands (ISBN: 978-90-8559-915-9)
-
Brugts MP 2009 IGF-I bioactivity in aging, health and disease. Doctoral Thesis 2009. Erasmus MC, University Medical Center Rotterdam, The Netherlands (ISBN: 978-90-8559-915-9).
-
(2009)
IGF-I Bioactivity in Aging, Health and Disease
-
-
Brugts, M.P.1
-
8
-
-
47549110969
-
Normal values of circulating insulin-like growth factor-I bioactivity in the healthy population: Comparison with five widely used IGF-I immunoassays
-
doi:10.1210/jc.2007-2454
-
Brugts MP, Ranke MB, Hofland LJ, van der Wansem K, Weber K, Frystyk J, Lamberts SW & Janssen JA 2008 Normal values of circulating insulin-like growth factor-I bioactivity in the healthy population: comparison with five widely used IGF-I immunoassays. Journal of Clinical Endocrinology and Metabolism 93 2539-2545. (doi:10.1210/jc.2007-2454)
-
(2008)
Journal of Clinical Endocrinology and Metabolism
, vol.93
, pp. 2539-2545
-
-
Brugts, M.P.1
Ranke, M.B.2
Hofland, L.J.3
Van Der Wansem, K.4
Weber, K.5
Frystyk, J.6
Lamberts, S.W.7
Janssen, J.A.8
-
9
-
-
23044521031
-
Insulin through the ages: Phylogeny of a growth promoting and metabolic regulatory hormone
-
doi:10.1668/0003-1569(2000)040[0213:ITTAPO]2.0.CO;2
-
Chan SJ & Steiner DF 2000 Insulin through the ages: phylogeny of a growth promoting and metabolic regulatory hormone. American Zoologist 40 213-222. (doi:10.1668/0003-1569(2000)040[0213:ITTAPO]2.0.CO;2)
-
(2000)
American Zoologist
, vol.40
, pp. 213-222
-
-
Chan, S.J.1
Steiner, D.F.2
-
10
-
-
84867419897
-
Mechanisims of insulin action
-
Eds AR Saltiel & JE Pessin. Springer/Landes Bioscience: New York, NY, USA
-
De Meyts S, Palsgaard J, Theede A-M, Gauguin L, Aladdin H & Whittaker J 2007 Mechanisims of insulin action. In Insulin and IGF-I Receptor Structure and Binding Mechanism. pp 1-32. Eds AR Saltiel & JE Pessin. Springer/Landes Bioscience: New York, NY, USA.
-
(2007)
Insulin and IGF-I Receptor Structure and Binding Mechanism
, pp. 1-32
-
-
De Meyts, S.1
Palsgaard, J.2
Theede, A.-M.3
Gauguin, L.4
Aladdin, H.5
Whittaker, J.6
-
11
-
-
5044227353
-
Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR
-
doi:10.1210/me.2004-0183
-
Denley A, Bonython ER, Booker GW, Cosgrove LJ, Forbes BE, Ward CW & Wallace JC 2004 Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR. Molecular Endocrinology 18 2502-2512. (doi:10.1210/me.2004- 0183)
-
(2004)
Molecular Endocrinology
, vol.18
, pp. 2502-2512
-
-
Denley, A.1
Bonython, E.R.2
Booker, G.W.3
Cosgrove, L.J.4
Forbes, B.E.5
Ward, C.W.6
Wallace, J.C.7
-
12
-
-
0027097641
-
The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake
-
doi:10.1002/dmr.5610080305
-
Drejer K 1992 The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake. Diabetes/Metabolism Reviews 8 259-285. (doi:10.1002/dmr.5610080305)
-
(1992)
Diabetes/Metabolism Reviews
, vol.8
, pp. 259-285
-
-
Drejer, K.1
-
13
-
-
0025990972
-
Receptor binding and tyrosine kinase activation by insulin analogues with extreme affinities studied in human hepatoma HepG2 cells
-
doi:10.2337/diabetes.40.11.1488
-
Drejer K, Kruse V, Larsen UD, Hougaard P, Bjorn S & Gammeltoft S 1991 Receptor binding and tyrosine kinase activation by insulin analogues with extreme affinities studied in human hepatoma HepG2 cells. Diabetes 40 1488-1495. (doi:10.2337/diabetes.40.11.1488)
-
(1991)
Diabetes
, vol.40
, pp. 1488-1495
-
-
Drejer, K.1
Kruse, V.2
Larsen, U.D.3
Hougaard, P.4
Bjorn, S.5
Gammeltoft, S.6
-
14
-
-
0035742583
-
Insulin and insulin-like growth factor i receptors: Similarities and differences in signal transduction
-
doi:10.1159/000063469
-
Dupont J & LeRoith D 2001 Insulin and insulin-like growth factor I receptors: similarities and differences in signal transduction. Hormone Research 55 (Suppl 2) 22-26. (doi:10.1159/000063469)
-
(2001)
Hormone Research
, vol.55
, Issue.SUPPL. 2
, pp. 22-26
-
-
Dupont, J.1
LeRoith, D.2
-
15
-
-
35848933452
-
IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts
-
doi:10.1007/s00125-007-0815-9
-
Eckardt K, May C, Koenen M & Eckel J 2007 IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts. Diabetologia 50 2534-2543. (doi:10.1007/s00125-007-0815- 9)
-
(2007)
Diabetologia
, vol.50
, pp. 2534-2543
-
-
Eckardt, K.1
May, C.2
Koenen, M.3
Eckel, J.4
-
16
-
-
0018937820
-
Role of zinc in insulin biosynthesis. Some possible zinc-insulin interactions in the pancreatic B-cell
-
doi:10.1007/BF00275265
-
Emdin SO, Dodson GG, Cutfield JM & Cutfield SM 1980 Role of zinc in insulin biosynthesis. Some possible zinc-insulin interactions in the pancreatic B-cell. Diabetologia 19 174-182. (doi:10.1007/BF00275265)
-
(1980)
Diabetologia
, vol.19
, pp. 174-182
-
-
Emdin, S.O.1
Dodson, G.G.2
Cutfield, J.M.3
Cutfield, S.M.4
-
17
-
-
47349101284
-
The role of insulin receptors and IGF-I receptors in cancer and other diseases
-
doi:10.1080/13813450801969715
-
Frasca F, Pandini G, Sciacca L, Pezzino V, Squatrito S, Belfiore A & Vigneri R 2008 The role of insulin receptors and IGF-I receptors in cancer and other diseases. Archives of Physiology and Biochemistry 114 23-37. (doi:10.1080/13813450801969715)
-
(2008)
Archives of Physiology and Biochemistry
, vol.114
, pp. 23-37
-
-
Frasca, F.1
Pandini, G.2
Sciacca, L.3
Pezzino, V.4
Squatrito, S.5
Belfiore, A.6
Vigneri, R.7
-
18
-
-
2342441415
-
Metabolic effects of insulin-like growth factor-I and possible therapeutic aspects in diabetes
-
Eds A Flyvbjerg, H Ørskov & KGMM Alberti. Wiley: Chicester, West Sussex, UK
-
Froesch ER, Zenobi PD & Zapf J 1993 Metabolic effects of insulin-like growth factor-I and possible therapeutic aspects in diabetes. In Growth hormone and Insulin-like Growth Factor, pp 109-129. Eds A Flyvbjerg, H Ørskov & KGMM Alberti. Wiley: Chicester, West Sussex, UK.
-
(1993)
Growth Hormone and Insulin-like Growth Factor
, pp. 109-129
-
-
Froesch, E.R.1
Zenobi, P.D.2
Zapf, J.3
-
19
-
-
0025865344
-
Overexpression of insulin receptors in fibroblast and ovary cells induces a ligand-mediated transformed phenotype
-
doi:10.1210/mend-5-3-452
-
Giorgino F, Belfiore A, Milazzo G, Costantino A, Maddux B, Whittaker J, Goldfine ID & Vigneri R 1991 Overexpression of insulin receptors in fibroblast and ovary cells induces a ligand-mediated transformed phenotype. Molecular Endocrinology 5 452-459. (doi:10.1210/mend-5-3-452)
-
(1991)
Molecular Endocrinology
, vol.5
, pp. 452-459
-
-
Giorgino, F.1
Belfiore, A.2
Milazzo, G.3
Costantino, A.4
Maddux, B.5
Whittaker, J.6
Goldfine, I.D.7
Vigneri, R.8
-
20
-
-
47049110494
-
Insulin analogues with increased mitogenic potency - Are they safe?
-
doi:10.1055/s-2008-1062740
-
Hansen BF 2008 Insulin analogues with increased mitogenic potency - are they safe? Hormone and Metabolic Research 40 431-433. (doi:10.1055/s-2008- 1062740)
-
(2008)
Hormone and Metabolic Research
, vol.40
, pp. 431-433
-
-
Hansen, B.F.1
-
21
-
-
0029862845
-
Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency
-
Hansen BF, Danielsen GM, Drejer K, Sorensen AR, Wiberg FC, Klein HH & Lundemose AG 1996 Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency. Biochemical Journal 315 (Pt 1) 271-279.
-
(1996)
Biochemical Journal
, vol.315
, Issue.PART 1
, pp. 271-279
-
-
Hansen, B.F.1
Danielsen, G.M.2
Drejer, K.3
Sorensen, A.R.4
Wiberg, F.C.5
Klein, H.H.6
Lundemose, A.G.7
-
22
-
-
80054685557
-
Insulin X10 revisited: A super-mitogenic insulin analogue
-
doi:10.1007/s00125-011-2203-8
-
Hansen BF, Kurtzhals P, Jensen AB, Dejgaard A & Russell-Jones D 2011 Insulin X10 revisited: a super-mitogenic insulin analogue. Diabetologia 54 2226-2231. (doi:10.1007/s00125-011-2203-8)
-
(2011)
Diabetologia
, vol.54
, pp. 2226-2231
-
-
Hansen, B.F.1
Kurtzhals, P.2
Jensen, A.B.3
Dejgaard, A.4
Russell-Jones, D.5
-
23
-
-
0033256370
-
Mechanisms of nuclear translocation of insulin
-
doi:10.1007/BF02738245
-
Harada S, Smith RM & Jarett L 1999 Mechanisms of nuclear translocation of insulin. Cell Biochemistry and Biophysics 31 307-319. (doi:10.1007/BF02738245)
-
(1999)
Cell Biochemistry and Biophysics
, vol.31
, pp. 307-319
-
-
Harada, S.1
Smith, R.M.2
Jarett, L.3
-
24
-
-
4344701890
-
The mechanism of protraction of insulin detemir, a long-acting, acylated analog of human insulin
-
doi:10.1023/B:PHAM.0000036926.54824.37
-
Havelund S, Plum A, Ribel U, Jonassen I, Volund A, Markussen J & Kurtzhals P 2004 The mechanism of protraction of insulin detemir, a long-acting, acylated analog of human insulin. Pharmacological Research 21 1498-1504. (doi:10.1023/B:PHAM.0000036926.54824.37)
-
(2004)
Pharmacological Research
, vol.21
, pp. 1498-1504
-
-
Havelund, S.1
Plum, A.2
Ribel, U.3
Jonassen, I.4
Volund, A.5
Markussen, J.6
Kurtzhals, P.7
-
25
-
-
2542576404
-
Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes
-
doi:10.2337/diabetes.53.6.1614
-
Heise T, Nosek L, Ronn BB, Endahl L, Heinemann L, Kapitza C & Draeger E 2004 Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes. Diabetes 53 1614-1620. (doi:10.2337/diabetes.53.6.1614)
-
(2004)
Diabetes
, vol.53
, pp. 1614-1620
-
-
Heise, T.1
Nosek, L.2
Ronn, B.B.3
Endahl, L.4
Heinemann, L.5
Kapitza, C.6
Draeger, E.7
-
26
-
-
12744259889
-
Insulin glulisine: Insulin receptor signaling characteristics in vivo
-
Hennige AM, Lehmann R, Weigert C, Moeschel K, Schauble M, Metzinger E, Lammers R & Haring HU 2005 Insulin glulisine: insulin receptor signaling characteristics in vivo. Diabetes 54 361-366.
-
(2005)
Diabetes
, vol.54
, pp. 361-366
-
-
Hennige, A.M.1
Lehmann, R.2
Weigert, C.3
Moeschel, K.4
Schauble, M.5
Metzinger, E.6
Lammers, R.7
Haring, H.U.8
-
27
-
-
0025700681
-
Insulin-like growth factors i and II
-
doi:10.1111/j.1432-1033.1990.tb15595.x
-
Humbel RE 1990 Insulin-like growth factors I and II. European Journal of Biochemistry 190 445-462. (doi:10.1111/j.1432-1033.1990.tb15595.x)
-
(1990)
European Journal of Biochemistry
, vol.190
, pp. 445-462
-
-
Humbel, R.E.1
-
28
-
-
0043198265
-
Serum levels of insulin-like growth factor i and its binding proteins in health and disease
-
doi:10.1016/S1096-6374(03)00038-8
-
Juul A 2003 Serum levels of insulin-like growth factor I and its binding proteins in health and disease. Growth Hormone & IGF Research 13 113-170. (doi:10.1016/S1096-6374(03)00038-8)
-
(2003)
Growth Hormone & IGF Research
, vol.13
, pp. 113-170
-
-
Juul, A.1
-
29
-
-
33847364416
-
pI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity
-
Kohn WD, Micanovic R, Myers SL, Vick AM, Kahl SD, Zhang L, Strifler BA, Li S, Shang J, Beals JM et al. 2007 pI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity. Peptides 28 935-948.
-
(2007)
Peptides
, vol.28
, pp. 935-948
-
-
Kohn, W.D.1
Micanovic, R.2
Myers, S.L.3
Vick, A.M.4
Kahl, S.D.5
Zhang, L.6
Strifler, B.A.7
Li, S.8
Shang, J.9
Beals, J.M.10
-
30
-
-
0347296059
-
Biotransformation of insulin glargine after subcutaneous injection in healthy subjects
-
doi:10.1185/030079902125001416
-
Kuerzel GU, Shukla U, Scholtz HE, Pretorius SG, Wessels DH, Venter C, Potgieter MA, Lang AM, Koose T & Bernhardt E 2003 Biotransformation of insulin glargine after subcutaneous injection in healthy subjects. Current Medical Research and Opinion 19 34-40. (doi:10.1185/030079902125001416)
-
(2003)
Current Medical Research and Opinion
, vol.19
, pp. 34-40
-
-
Kuerzel, G.U.1
Shukla, U.2
Scholtz, H.E.3
Pretorius, S.G.4
Wessels, D.H.5
Venter, C.6
Potgieter, M.A.7
Lang, A.M.8
Koose, T.9
Bernhardt, E.10
-
31
-
-
0342657181
-
Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
-
doi:10.2337/diabetes.49.6.999
-
Kurtzhals P, Schaffer L, Sorensen A, Kristensen C, Jonassen I, Schmid C & Trub T 2000 Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use. Diabetes 49 999-1005. (doi:10.2337/diabetes.49.6.999)
-
(2000)
Diabetes
, vol.49
, pp. 999-1005
-
-
Kurtzhals, P.1
Schaffer, L.2
Sorensen, A.3
Kristensen, C.4
Jonassen, I.5
Schmid, C.6
Trub, T.7
-
32
-
-
0002497850
-
Molecular and cellular biology of the insulin-like growth factors
-
Ed BD Weintraub. Raven Press: New York, NY, USA
-
LeRoith D, Adamo D, Werner H & Roberts Jr CT 1995 Molecular and cellular biology of the insulin-like growth factors. In Molecular Endocrinology, Basic Concepts and Clinical Correlations, pp 181-183. Ed BD Weintraub. Raven Press: New York, NY, USA.
-
(1995)
Molecular Endocrinology, Basic Concepts and Clinical Correlations
, pp. 181-183
-
-
LeRoith, D.1
Adamo, D.2
Werner, H.3
Roberts Jr., C.T.4
-
33
-
-
47049123594
-
Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-1
-
Liefvendahl E & Arnqvist HJ 2008 Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-1. Hormone and Metabolic Research 40 369-374.
-
(2008)
Hormone and Metabolic Research
, vol.40
, pp. 369-374
-
-
Liefvendahl, E.1
Arnqvist, H.J.2
-
34
-
-
9044226136
-
Soluble, fatty acid acylated insulins bind to albumin and show protracted action in pigs
-
doi:10.1007/BF00418343
-
Markussen J, Havelund S, Kurtzhals P, Andersen AS, Halstrom J, Hasselager E, Larsen UD, Ribel U, Schaffer L, Vad K et al. 1996 Soluble, fatty acid acylated insulins bind to albumin and show protracted action in pigs. Diabetologia 39 281-288. (doi:10.1007/BF00418343)
-
(1996)
Diabetologia
, vol.39
, pp. 281-288
-
-
Markussen, J.1
Havelund, S.2
Kurtzhals, P.3
Andersen, A.S.4
Halstrom, J.5
Hasselager, E.6
Larsen, U.D.7
Ribel, U.8
Schaffer, L.9
Vad, K.10
-
35
-
-
47349085657
-
Proliferative effects of insulin analogues on mammary epithelial cells
-
doi:10.1080/13813450801900645
-
Mayer D, Shukla A & Enzmann H 2008 Proliferative effects of insulin analogues on mammary epithelial cells. Archives of Physiology and Biochemistry 114 38-44. (doi:10.1080/13813450801900645)
-
(2008)
Archives of Physiology and Biochemistry
, vol.114
, pp. 38-44
-
-
Mayer, D.1
Shukla, A.2
Enzmann, H.3
-
36
-
-
0030614323
-
ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: Evidence for enhanced interactions with the insulin-like growth factor-I receptor
-
doi:10.1002/(SICI)1098-2744(199701)18:1 〈19::AID-MC3〉 3.0.CO;2-M
-
Milazzo G, Sciacca L, Papa V, Goldfine ID & Vigneri R 1997 ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: evidence for enhanced interactions with the insulin-like growth factor-I receptor. Molecular Carcinogenesis 18 19-25. (doi:10.1002/(SICI)1098-2744(199701)18:1 〈19::AID-MC3〉 3.0.CO;2-M)
-
(1997)
Molecular Carcinogenesis
, vol.18
, pp. 19-25
-
-
Milazzo, G.1
Sciacca, L.2
Papa, V.3
Goldfine, I.D.4
Vigneri, R.5
-
37
-
-
0024403208
-
Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man
-
doi:10.1210/mend-3-8-1263
-
Moller DE, Yokota A, Caro JF & Flier JS 1989 Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man. Molecular Endocrinology 3 1263-1269. (doi:10.1210/mend-3-8-1263)
-
(1989)
Molecular Endocrinology
, vol.3
, pp. 1263-1269
-
-
Moller, D.E.1
Yokota, A.2
Caro, J.F.3
Flier, J.S.4
-
38
-
-
0025362295
-
Functionally distinct insulin receptors generated by tissue-specific alternative splicing
-
Mosthaf L, Grako K, Dull TJ, Coussens L, Ullrich A & McClain DA 1990 Functionally distinct insulin receptors generated by tissue-specific alternative splicing. EMBO Journal 9 2409-2413.
-
(1990)
EMBO Journal
, vol.9
, pp. 2409-2413
-
-
Mosthaf, L.1
Grako, K.2
Dull, T.J.3
Coussens, L.4
Ullrich, A.5
McClain, D.A.6
-
39
-
-
78650190900
-
Insulin glargine and NPH insulin increase to a similar degree epithelial cell proliferation and aberrant crypt foci formation in colons of diabetic mice
-
doi:10.1007/s12672-010-0020-z
-
Nagel JM, Staffa J, Renner-Muller I, Horst D, Vogeser M, Langkamp M, Hoeflich A, Goke B, Kolligs FT & Mantzoros CS 2010 Insulin glargine and NPH insulin increase to a similar degree epithelial cell proliferation and aberrant crypt foci formation in colons of diabetic mice. Hormones & Cancer 1 320-330. (doi:10.1007/s12672-010-0020-z)
-
(2010)
Hormones & Cancer
, vol.1
, pp. 320-330
-
-
Nagel, J.M.1
Staffa, J.2
Renner-Muller, I.3
Horst, D.4
Vogeser, M.5
Langkamp, M.6
Hoeflich, A.7
Goke, B.8
Kolligs, F.T.9
Mantzoros, C.S.10
-
40
-
-
0023645553
-
Role of the COOH-terminal B-chain domain in insulin-receptor interactions. Identification of perturbations involving the insulin mainchain
-
Nakagawa SH & Tager HS 1987 Role of the COOH-terminal B-chain domain in insulin-receptor interactions. Identification of perturbations involving the insulin mainchain. Journal of Biological Chemistry 262 12054-12058.
-
(1987)
Journal of Biological Chemistry
, vol.262
, pp. 12054-12058
-
-
Nakagawa, S.H.1
Tager, H.S.2
-
41
-
-
78751553994
-
Direct recruitment of insulin receptor and ERK signaling cascade to insulin-inducible gene loci
-
doi:10.2337/db09-1806
-
Nelson JD, LeBoeuf RC & Bomsztyk K 2011 Direct recruitment of insulin receptor and ERK signaling cascade to insulin-inducible gene loci. Diabetes 60 127-137. (doi:10.2337/db09-1806)
-
(2011)
Diabetes
, vol.60
, pp. 127-137
-
-
Nelson, J.D.1
LeBoeuf, R.C.2
Bomsztyk, K.3
-
42
-
-
0028953352
-
Long-term comparison of human insulin analogue B10Asp and soluble human insulin in IDDM patients on a basal/bolus insulin regimen
-
doi:10.1007/BF00400729
-
Nielsen FS, Jorgensen LN, Ipsen M, Voldsgaard AI & Parving HH 1995 Long-term comparison of human insulin analogue B10Asp and soluble human insulin in IDDM patients on a basal/bolus insulin regimen. Diabetologia 38 592-598. (doi:10.1007/BF00400729)
-
(1995)
Diabetologia
, vol.38
, pp. 592-598
-
-
Nielsen, F.S.1
Jorgensen, L.N.2
Ipsen, M.3
Voldsgaard, A.I.4
Parving, H.H.5
-
44
-
-
50049132424
-
Beyond the era of NPH insulin - Long-acting insulin analogs: Chemistry, comparative pharmacology, and clinical application
-
doi:10.1089/dia.2008.0023
-
Owens DR & Bolli GB 2008 Beyond the era of NPH insulin - long-acting insulin analogs: chemistry, comparative pharmacology, and clinical application. Diabetes Technology & Therapeutics 10 333-349. (doi:10.1089/dia.2008.0023)
-
(2008)
Diabetes Technology & Therapeutics
, vol.10
, pp. 333-349
-
-
Owens, D.R.1
Bolli, G.B.2
-
45
-
-
0037131385
-
Insulin/insulin-like growth factor i hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved
-
doi:10.1074/jbc.M202766200
-
Pandini G, Frasca F, Mineo R, Sciacca L, Vigneri R & Belfiore A 2002 Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved. Journal of Biological Chemistry 277 39684-39695. (doi:10.1074/jbc.M202766200)
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 39684-39695
-
-
Pandini, G.1
Frasca, F.2
Mineo, R.3
Sciacca, L.4
Vigneri, R.5
Belfiore, A.6
-
46
-
-
0023279622
-
Nuclear translocation of the insulin receptor. A possible mediator of insulin's long term effects
-
Podlecki DA, Smith RM, Kao M, Tsai P, Huecksteadt T, Brandenburg D, Lasher RS, Jarett L & Olefsky JM 1987 Nuclear translocation of the insulin receptor. A possible mediator of insulin's long term effects. Journal of Biological Chemistry 262 3362-3368.
-
(1987)
Journal of Biological Chemistry
, vol.262
, pp. 3362-3368
-
-
Podlecki, D.A.1
Smith, R.M.2
Kao, M.3
Tsai, P.4
Huecksteadt, T.5
Brandenburg, D.6
Lasher, R.S.7
Jarett, L.8
Olefsky, J.M.9
-
47
-
-
56749184290
-
Insulin and insulin-like growth factor signalling in neoplasia
-
doi:10.1038/nrc2536
-
Pollak M 2008 Insulin and insulin-like growth factor signalling in neoplasia. Nature Reviews. Cancer 8 915-928. (doi:10.1038/nrc2536)
-
(2008)
Nature Reviews. Cancer
, vol.8
, pp. 915-928
-
-
Pollak, M.1
-
48
-
-
0018184054
-
The amino acid sequence of human insulin-like growth factor i and its structural homology with proinsulin
-
Rinderknecht E & Humbel RE 1978 The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. Journal of Biological Chemistry 253 2769-2776.
-
(1978)
Journal of Biological Chemistry
, vol.253
, pp. 2769-2776
-
-
Rinderknecht, E.1
Humbel, R.E.2
-
49
-
-
68149134500
-
Growth effects of insulin and insulin analogues
-
doi:10.1080/13813450902835690
-
Sandow J 2009 Growth effects of insulin and insulin analogues. Archives of Physiology and Biochemistry 115 72-85. (doi:10.1080/13813450902835690)
-
(2009)
Archives of Physiology and Biochemistry
, vol.115
, pp. 72-85
-
-
Sandow, J.1
-
50
-
-
77955515434
-
Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling
-
doi:10.1007/s00125-010-1760-6
-
Sciacca L, Cassarino MF, Genua M, Pandini G, Le Moli R, Squatrito S & Vigneri R 2010 Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling. Diabetologia 53 1743-1753. (doi:10.1007/s00125- 010-1760-6)
-
(2010)
Diabetologia
, vol.53
, pp. 1743-1753
-
-
Sciacca, L.1
Cassarino, M.F.2
Genua, M.3
Pandini, G.4
Le Moli, R.5
Squatrito, S.6
Vigneri, R.7
-
51
-
-
0034877139
-
Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors
-
doi:10.1042/BST0290513
-
Siddle K, Urso B, Niesler CA, Cope DL, Molina L, Surinya KH & Soos MA 2001 Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors. Biochemical Society Transactions 29 513-525. (doi:10.1042/BST0290513)
-
(2001)
Biochemical Society Transactions
, vol.29
, pp. 513-525
-
-
Siddle, K.1
Urso, B.2
Niesler, C.A.3
Cope, D.L.4
Molina, L.5
Surinya, K.H.6
Soos, M.A.7
-
52
-
-
8544226918
-
Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor
-
doi:10.1007/s001250051402
-
Slieker LJ, Brooke GS, DiMarchi RD, Flora DB, Green LK, Hoffmann JA, Long HB, Fan L, Shields JE, Sundell KL et al. 1997 Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor. Diabetologia 40 (Suppl 2) S54-S61. (doi:10.1007/s001250051402)
-
(1997)
Diabetologia
, vol.40
, Issue.SUPPL. 2
-
-
Slieker, L.J.1
Brooke, G.S.2
DiMarchi, R.D.3
Flora, D.B.4
Green, L.K.5
Hoffmann, J.A.6
Long, H.B.7
Fan, L.8
Shields, J.E.9
Sundell, K.L.10
-
53
-
-
77949760139
-
In vitro metabolic and mitogenic signaling of insulin glargine and its metabolites
-
Sommerfeld MR, Muller G, Tschank G, Seipke G, Habermann P, Kurrle R & Tennagels N 2010 In vitro metabolic and mitogenic signaling of insulin glargine and its metabolites. PLoS One 5 e9540.
-
(2010)
PLoS One
, vol.5
-
-
Sommerfeld, M.R.1
Muller, G.2
Tschank, G.3
Seipke, G.4
Habermann, P.5
Kurrle, R.6
Tennagels, N.7
-
54
-
-
33947601038
-
Comparison of the mitogenic potency of regular human insulin and its analogue glargine in normal and transformed human breast epithelial cells
-
doi:10.1055/s-2007-957352
-
Staiger K, Hennige AM, Staiger H, Haring HU & Kellerer M 2007 Comparison of the mitogenic potency of regular human insulin and its analogue glargine in normal and transformed human breast epithelial cells. Hormone and Metabolic Research 39 65-67. (doi:10.1055/s-2007-957352)
-
(2007)
Hormone and Metabolic Research
, vol.39
, pp. 65-67
-
-
Staiger, K.1
Hennige, A.M.2
Staiger, H.3
Haring, H.U.4
Kellerer, M.5
-
55
-
-
33644686238
-
Insulin glulisine - A comprehensive preclinical evaluation
-
doi:10.1080/10915810500488379
-
Stammberger I, Seipke G & Bartels T 2006 Insulin glulisine - a comprehensive preclinical evaluation. International Journal of Toxicology 25 25-33. (doi:10.1080/10915810500488379)
-
(2006)
International Journal of Toxicology
, vol.25
, pp. 25-33
-
-
Stammberger, I.1
Seipke, G.2
Bartels, T.3
-
57
-
-
77952910442
-
The history of diabetes
-
Eds JC Pickup, G Williams. Blackwell Science: Boston, MA, USA
-
Tattersall RB 2003 The history of diabetes. In Textbook of Diabetes , pp 1.1-1.22. Eds JC Pickup, G Williams. Blackwell Science: Boston, MA, USA.
-
(2003)
Textbook of Diabetes
-
-
Tattersall, R.B.1
-
58
-
-
0038418746
-
Insulin detemir is associated with more predictable glycemic control and reduced risk of hypoglycemia than NPH insulin in patients with type 1 diabetes on a basal-bolus regimen with premeal insulin aspart
-
doi:10.2337/diacare.26.3.590
-
Vague P, Selam JL, Skeie S, De Leeuw I, Elte JW, Haahr H, Kristensen A & Draeger E 2003 Insulin detemir is associated with more predictable glycemic control and reduced risk of hypoglycemia than NPH insulin in patients with type 1 diabetes on a basal-bolus regimen with premeal insulin aspart. Diabetes Care 26 590-596. (doi:10.2337/diacare.26.3.590)
-
(2003)
Diabetes Care
, vol.26
, pp. 590-596
-
-
Vague, P.1
Selam, J.L.2
Skeie, S.3
De Leeuw, I.4
Elte, J.W.5
Haahr, H.6
Kristensen, A.7
Draeger, E.8
-
59
-
-
78649633536
-
Insulin glargine is more potent in activating the human IGF-I receptor than human insulin and insulin detemir
-
doi:10.1016/j.ghir.2010.10.002
-
Varewijck AJ, Goudzwaard JA, Brugts MP, Lamberts SW, Hofland LJ & Janssen JA 2010 Insulin glargine is more potent in activating the human IGF-I receptor than human insulin and insulin detemir. Growth Hormone & IGF Research 20 427-431. (doi:10.1016/j.ghir.2010.10.002)
-
(2010)
Growth Hormone & IGF Research
, vol.20
, pp. 427-431
-
-
Varewijck, A.J.1
Goudzwaard, J.A.2
Brugts, M.P.3
Lamberts, S.W.4
Hofland, L.J.5
Janssen, J.A.6
-
60
-
-
84862553178
-
Addition of insulin glargine or NPH insulin to metformin monotherapy in poorly controlled type 2 diabetic patients decreases IGF-I bioactivity similarly
-
doi:10.1007/s00125-011-2435-7
-
Varewijck AJ, Janssen JA, Vahatalo M, Hofland LJ, Lamberts SW & Yki-Jarvinen H 2012 Addition of insulin glargine or NPH insulin to metformin monotherapy in poorly controlled type 2 diabetic patients decreases IGF-I bioactivity similarly. Diabetologia 55 1186-1194. (doi:10.1007/s00125-011-2435- 7)
-
(2012)
Diabetologia
, vol.55
, pp. 1186-1194
-
-
Varewijck, A.J.1
Janssen, J.A.2
Vahatalo, M.3
Hofland, L.J.4
Lamberts, S.W.5
Yki-Jarvinen, H.6
-
61
-
-
72549116243
-
Diabetes and cancer
-
doi:10.1677/ERC-09-0087
-
Vigneri P, Frasca F, Sciacca L, Pandini G & Vigneri R 2009 Diabetes and cancer. Endocrine-Related Cancer 16 1103-1123. (doi:10.1677/ERC-09-0087)
-
(2009)
Endocrine-Related Cancer
, vol.16
, pp. 1103-1123
-
-
Vigneri, P.1
Frasca, F.2
Sciacca, L.3
Pandini, G.4
Vigneri, R.5
-
62
-
-
78549247886
-
Insulin and its analogs: Actions via insulin and IGF receptors
-
doi:10.1007/s00592-010-0215-3
-
Vigneri R, Squatrito S & Sciacca L 2010 Insulin and its analogs: actions via insulin and IGF receptors. Acta Diabetologica 47 271-278. (doi:10.1007/s00592-010-0215-3)
-
(2010)
Acta Diabetologica
, vol.47
, pp. 271-278
-
-
Vigneri, R.1
Squatrito, S.2
Sciacca, L.3
-
63
-
-
33244479164
-
Insulin glargine or NPH combined with metformin in type 2 diabetes: The LANMET study
-
doi:10.1007/s00125-005-0132-0
-
Yki-Jarvinen H, Kauppinen-Makelin R, Tiikkainen M, Vahatalo M, Virtamo H, Nikkila K, Tulokas T, Hulme S, Hardy K, McNulty S et al. 2006 Insulin glargine or NPH combined with metformin in type 2 diabetes: the LANMET study. Diabetologia 49 442-451. (doi:10.1007/s00125-005-0132-0)
-
(2006)
Diabetologia
, vol.49
, pp. 442-451
-
-
Yki-Jarvinen, H.1
Kauppinen-Makelin, R.2
Tiikkainen, M.3
Vahatalo, M.4
Virtamo, H.5
Nikkila, K.6
Tulokas, T.7
Hulme, S.8
Hardy, K.9
McNulty, S.10
|