Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Gotte, Giovanni ^a   Mahmoud Helmy, Alexander ^a   Ercole, Carmine ^b   Spadaccini, Roberta ^c   Laurents, Douglas V ^d   Donadelli, Massimo ^a   Picone, Delia ^b  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF SANNIO   (Italy)

^d INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SEMINAL RIBONUCLEASE; POLYMER; RIBONUCLEASE; TETRAMER; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DRUG MECHANISM; DRUG STABILITY; ELECTROPHORESIS; ENZYME ACTIVITY; GEL PERMEATION CHROMATOGRAPHY; LIGHT SCATTERING; MOLECULAR MODEL; MOLECULAR WEIGHT; MUTAGENESIS; OLIGOMERIZATION; STRUCTURE ACTIVITY RELATION;

ACETIC ACID; ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; CELL SURVIVAL; CELLS, CULTURED; CHROMATOGRAPHY, GEL; CROSS-LINKING REAGENTS; DINITROFLUOROBENZENE; DISULFIDES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDORIBONUCLEASES; ENZYME STABILITY; KINETICS; MALE; MODELS, MOLECULAR; MUTATION; POLY A-U; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; TEMPERATURE;

EID: 84867409381     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046804     Document Type: Article

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