Inhibition of SOX17 by MicroRNA 141 and methylation activates the WNT signaling pathway in esophageal cancer

Journal of Molecular Diagnostics

Volumn 14, Issue 6, 2012, Pages 577-585

  Jia, Yan ^a,b   Yang, Yunsheng ^a   Zhan, Qimin ^c   Brock, Malcolm V ^d   Zheng, Xiaofei ^e   Yu, Yuanzi ^a,b   Herman, James G ^d   Guo, Mingzhou ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b NANKAI UNIVERSITY   (China)

^c CANCER HOSPITAL   (China)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BETA CATENIN; LUCIFERASE; MICRORNA 141; TRANSCRIPTION FACTOR SOX17;

ALCOHOL CONSUMPTION; ARTICLE; BIOASSAY; CANCER CELL CULTURE; CANCER DIAGNOSIS; CANCER GROWTH; CANCER TISSUE; COLONY FORMATION; CONTROLLED STUDY; DNA METHYLATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; ESOPHAGUS DYSPLASIA; ESOPHAGUS MUCOSA; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIMARY TUMOR; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WNT SIGNALING PATHWAY;

BETA CATENIN; CELL LINE, TUMOR; DOWN-REGULATION; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; METHYLATION; MICRORNAS; PROMOTER REGIONS, GENETIC; SOXF TRANSCRIPTION FACTORS; WNT SIGNALING PATHWAY;

EID: 84867404462     PISSN: 15251578     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmoldx.2012.06.004     Document Type: Article

References (29)

1. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, M.J. Thun Cancer statistics, 2009 CA Cancer J Clin 59 2009 225 249
2. F. Kamangar, G.M. Dores, W.F. Anderson Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world J Clin Oncol 24 2006 2137 2150
3. H. Pohl, H.G. Welch The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence J Natl Cancer Inst 97 2005 142 146
4. M. Guo, M.G. House, H. Suzuki, Y. Ye, M.V. Brock, F. Lu, Z. Liu, A.K. Rustgi, J.G. Herman Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer Int J Cancer 121 2007 1219 1226
5. M. Guo, S. Liu, F. Lu Gefitinib-sensitizing mutations in esophageal carcinoma N Engl J Med 354 2006 2193 2194
6. M. Guo, J. Ren, M.G. House, Y. Qi, M.V. Brock, J.G. Herman Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus Clin Cancer Res 12 2006 4515 4522
7. M.V. Brock, M. Gou, Y. Akiyama, A. Muller, T.T. Wu, E. Montgomery, M. Deasel, P. Germonpre, L. Rubinson, R.F. Heitmiller, S.C. Yang, A.A. Forastiere, S.B. Baylin, J.G. Herman Prognostic importance of promoter hypermethylation of multiple genes in esophageal adenocarcinoma Clin Cancer Res 9 2003 2912 2919
8. J. Kudo, T. Nishiwaki, N. Haruki, H. Ishiguro, Y. Shibata, Y. Terashita, H. Sugiura, N. Shinoda, M. Kimura, Y. Kuwabara, Y. Fujii Aberrant nuclear localization of beta-catenin without genetic alterations in beta-catenin or Axin genes in esophageal cancer World J Surg Oncol 5 2007 21
9. S. Salahshor, R. Naidoo, S. Serra, W. Shih, M.S. Tsao, R. Chetty, J.R. Woodgett Frequent accumulation of nuclear E-cadherin and alterations in the Wnt signaling pathway in esophageal squamous cell carcinomas Mod Pathol 21 2008 271 281
10. W. Zhang, S.C. Glockner, M. Guo, E.O. Machida, D.H. Wang, H. Easwaran, L. Van Neste, J.G. Herman, K.E. Schuebel, D.N. Watkins, N. Ahuja, S.B. Baylin Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer Cancer Res 68 2008 2764 2772
11. Y. Jia, Y. Yang, S. Liu, J.G. Herman, F. Lu, M. Guo SOX17 antagonizes WNT/beta-catenin signaling pathway in hepatocellular carcinoma Epigenetics 5 2010 743 749
12. M. Guo, M.G. House, Y. Akiyama, Y. Qi, D. Capagna, J. Harmon, S.B. Baylin, M.V. Brock, J.G. Herman Hypermethylation of the GATA gene family in esophageal cancer Int J Cancer 119 2006 2078 2083
13. J.G. Herman, J.R. Graff, S. Myohanen, B.D. Nelkin, S.B. Baylin Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands Proc Natl Acad Sci U S A 93 1996 9821 9826
14. I.M. Shih, J. Yu, T.C. He, B. Vogelstein, K.W. Kinzler The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression Cancer Res 60 2000 1671 1676
15. T. Qin, J. Jelinek, J. Si, J. Shu, J.P. Issa Mechanisms of resistance to 5-aza-2′-deoxycytidine in human cancer cell lines Blood 113 2009 659 667
16. E.A. Griffiths, S.D. Gore DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes Semin Hematol 45 2008 23 30
17. G.D. Eslick Epidemiology of esophageal cancer Gastroenterol Clin North Am 38 2009 17 25
18. J.N. Glickman Section II: pathology and pathologic staging of esophageal cancer Semin Thorac Cardiovasc Surg 15 2003 167 179
19. N.D. Freedman, C.C. Abnet, M.F. Leitzmann, T. Mouw, A.F. Subar, A.R. Hollenbeck, A. Schatzkin A prospective study of tobacco, alcohol, and the risk of esophageal and gastric cancer subtypes Am J Epidemiol 165 2007 1424 1433
20. V. Korinek, N. Barker, P.J. Morin, D. van Wichen, R. de Weger, K.W. Kinzler, B. Vogelstein, H. Clevers Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma Science 275 1997 1784 1787
21. D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
22. B.P. Lewis, I.H. Shih, M.W. Jones-Rhoades, D.P. Bartel, C.B. Burge Prediction of mammalian microRNA targets Cell 115 2003 787 798
23. A. Klaus, W. Birchmeier Wnt signalling and its impact on development and cancer Nat Rev Cancer 8 2008 387 398
24. H. Clevers Wnt/beta-catenin signaling in development and disease Cell 127 2006 469 480
25. D. Sinner, S. Rankin, M. Lee, A.M. Zorn Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes Development 131 2004 3069 3080
26. D. Sinner, J.J. Kordich, J.R. Spence, R. Opoka, S. Rankin, S.C. Lin, D. Jonatan, A.M. Zorn, J.M. Wells Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells Mol Cell Biol 27 2007 7802 7815
27. U. Burk, J. Schubert, U. Wellner, O. Schmalhofer, E. Vincan, S. Spaderna, T. Brabletz A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells EMBO Rep 9 2008 582 589
28. S. Hyun, J.H. Lee, H. Jin, J. Nam, B. Namkoong, G. Lee, J. Chung, V.N. Kim Conserved microRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K Cell 139 2009 1096 1108
29. H. Cheng, L. Zhang, D.E. Cogdell, H. Zheng, A.J. Schetter, M. Nykter, C.C. Harris, K. Chen, S.R. Hamilton, W. Zhang Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis PLoS One 6 2011 e17745