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Volumn 31, Issue 41, 2012, Pages 4484-4489

N-cadherin haploinsufficiency increases survival in a mouse model of pancreatic cancer

Author keywords

apoptosis; cell adhesion; invasion; matrix metalloproteinase

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; MATRILYSIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE CELL ADHESION MOLECULE; SONIC HEDGEHOG PROTEIN;

EID: 84867402835     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.574     Document Type: Article
Times cited : (28)

References (31)
  • 3
    • 0034695913 scopus 로고    scopus 로고
    • Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis
    • Hazan RB, Phillips GR, Qiao RF, Norton L, Aaronson SA. Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 2000; 148: 779-790.
    • (2000) J Cell Biol , vol.148 , pp. 779-790
    • Hazan, R.B.1    Phillips, G.R.2    Qiao, R.F.3    Norton, L.4    Aaronson, S.A.5
  • 4
    • 0033230475 scopus 로고    scopus 로고
    • N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression
    • Nieman MT, Prudoff RS, Johnson KR, Wheelock MJ. N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J Cell Biol 1999; 147: 631-644.
    • (1999) J Cell Biol , vol.147 , pp. 631-644
    • Nieman, M.T.1    Prudoff, R.S.2    Johnson, K.R.3    Wheelock, M.J.4
  • 6
    • 4143146567 scopus 로고    scopus 로고
    • Oncogenic K-ras drives cell cycle progression and phenotypic conversion of primary pancreatic duct epithelial cells
    • DOI 10.1158/0008-5472.CAN-04-0807
    • Agbunag C, Bar-Sagi D. Oncogenic K-ras drives cell cycle progression and phenotypic conversion of primary pancreatic duct epithelial cells. Cancer Res 2004; 64: 5659-5663. (Pubitemid 39095562)
    • (2004) Cancer Research , vol.64 , Issue.16 , pp. 5659-5663
    • Agbunag, C.1    Bar-Sagi, D.2
  • 9
    • 33846263431 scopus 로고    scopus 로고
    • 2-terminal kinase 1 and up-regulating N-cadherin expression
    • DOI 10.1158/0008-5472.CAN-06-2322
    • Shintani Y, Hollingsworth MA, Wheelock MJ, Johnson KR. Collagen I promotes metastasis in pancreatic cancer by activating c-Jun NH(2)-terminal kinase 1 and up-regulating N-cadherin expression. Cancer Res 2006; 66: 11745-11753. (Pubitemid 46094186)
    • (2006) Cancer Research , vol.66 , Issue.24 , pp. 11745-11753
    • Shintani, Y.1    Hollingsworth, M.A.2    Wheelock, M.J.3    Johnson, K.R.4
  • 10
    • 19344362405 scopus 로고    scopus 로고
    • G12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
    • DOI 10.1016/j.ccr.2005.04.023, PII S1535610805001285
    • Hingorani SR, Wang L, Multani AS, Combs C, Deramaudt TB, Hruban RH et al. Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 2005; 7: 469-483. (Pubitemid 40719130)
    • (2005) Cancer Cell , vol.7 , Issue.5 , pp. 469-483
    • Hingorani, S.R.1    Wang, L.2    Multani, A.S.3    Combs, C.4    Deramaudt, T.B.5    Hruban, R.H.6    Rustgi, A.K.7    Chang, S.8    Tuveson, D.A.9
  • 11
    • 14044256554 scopus 로고    scopus 로고
    • Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure
    • DOI 10.1161/01.RES.0000156274.72390.2c
    • Kostetskii I, Li J, Xiong Y, Zhou R, Ferrari VA, Patel VV et al. Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure. Circ Res 2005; 96: 346-354. (Pubitemid 40279909)
    • (2005) Circulation Research , vol.96 , Issue.3 , pp. 346-354
    • Kostetskii, I.1    Li, J.2    Xiong, Y.3    Zhou, R.4    Ferrari, V.A.5    Patel, V.V.6    Molkentin, J.D.7    Radice, G.L.8
  • 12
    • 12344335490 scopus 로고    scopus 로고
    • N-cadherin is not essential for limb mesenchymal chondrogenesis
    • DOI 10.1002/dvdy.20241
    • Luo Y, Kostetskii I, Radice GL. N-cadherin is not essential for limb mesenchymal chondrogenesis. Dev Dyn 2005; 232: 336-344. (Pubitemid 40129786)
    • (2005) Developmental Dynamics , vol.232 , Issue.2 , pp. 336-344
    • Luo, Y.1    Kostetskii, I.2    Radice, G.L.3
  • 13
    • 77953510208 scopus 로고    scopus 로고
    • Ncadherin is dispensable for pancreas development but required for beta-cell granule turnover
    • Johansson JK, Voss U, Kesavan G, Kostetskii I, Wierup N, Radice GL et al. Ncadherin is dispensable for pancreas development but required for beta-cell granule turnover. Genesis 2010; 48: 374-381.
    • (2010) Genesis , vol.48 , pp. 374-381
    • Johansson, J.K.1    Voss, U.2    Kesavan, G.3    Kostetskii, I.4    Wierup, N.5    Radice, G.L.6
  • 15
    • 0036781973 scopus 로고    scopus 로고
    • A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor
    • DOI 10.1016/S1535-6108(02)00150-2
    • Suyama K, Shapiro I, Guttman M, Hazan RB. A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor. Cancer Cell 2002; 2: 301-314. (Pubitemid 41043964)
    • (2002) Cancer Cell , vol.2 , Issue.4 , pp. 301-314
    • Suyama, K.1    Shapiro, I.2    Guttman, M.3    Hazan, R.B.4
  • 20
    • 77449156435 scopus 로고    scopus 로고
    • The developmental transcription factor Gata4 is overexpressed in pancreatic ductal adenocarcinoma
    • Karafin MS, Cummings CT, Fu B, Iacobuzio-Donahue CA. The developmental transcription factor Gata4 is overexpressed in pancreatic ductal adenocarcinoma. Int J Clin Exp Pathol 2009; 3: 47-55.
    • (2009) Int J Clin Exp Pathol , vol.3 , pp. 47-55
    • Karafin, M.S.1    Cummings, C.T.2    Fu, B.3    Iacobuzio-Donahue, C.A.4
  • 21
    • 0036266409 scopus 로고    scopus 로고
    • Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas
    • DOI 10.1172/JCI200215051
    • Crawford HC, Scoggins CR, Washington MK, Matrisian LM, Leach SD. Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. J Clin Invest 2002; 109: 1437-1444. (Pubitemid 34596169)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.11 , pp. 1437-1444
    • Crawford, H.C.1    Scoggins, C.R.2    Kay Washington, M.3    Matrisian, L.M.4    Leach, S.D.5
  • 22
    • 79953761842 scopus 로고    scopus 로고
    • Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression
    • Fukuda A, Wang SC, Morris IV JP, Folias AE, Liou A, Kim GE et al. Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression. Cancer Cell 2011; 19: 441-455.
    • (2011) Cancer Cell , vol.19 , pp. 441-455
    • Fukuda, A.1    Wang, S.C.2    Morris, I.V.J.P.3    Folias, A.E.4    Liou, A.5    Kim, G.E.6
  • 24
    • 0034945537 scopus 로고    scopus 로고
    • N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling
    • DOI 10.1038/35083041
    • Cavallaro U, Niedermeyer J, Fuxa M, Christofori G. N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling. Nat Cell Biol 2001; 3: 650-657. (Pubitemid 32624421)
    • (2001) Nature Cell Biology , vol.3 , Issue.7 , pp. 650-657
    • Cavallaro, U.1    Niedermeyer, J.2    Fuxa, M.3    Christofori, G.4
  • 25
    • 53549133947 scopus 로고    scopus 로고
    • NCAMinduced focal adhesion assembly: A functional switch upon loss of E-cadherin
    • Lehembre F, Yilmaz M, Wicki A, Schomber T, Strittmatter K, Ziegler D et al. NCAMinduced focal adhesion assembly: a functional switch upon loss of E-cadherin. EMBO J 2008; 27: 2603-2615.
    • (2008) EMBO J , vol.27 , pp. 2603-2615
    • Lehembre, F.1    Yilmaz, M.2    Wicki, A.3    Schomber, T.4    Strittmatter, K.5    Ziegler, D.6
  • 26
    • 67149143399 scopus 로고    scopus 로고
    • Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
    • Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D et al. Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 2009; 324: 1457-1461.
    • (2009) Science , vol.324 , pp. 1457-1461
    • Olive, K.P.1    Jacobetz, M.A.2    Davidson, C.J.3    Gopinathan, A.4    McIntyre, D.5    Honess, D.6
  • 29
    • 33646103902 scopus 로고    scopus 로고
    • The cell surface membrane proteins Cdo and Boc are components and targets of the hedgehog signaling pathway and feedback network in mice
    • Tenzen T, Allen BL, Cole F, Kang JS, Krauss RS, McMahon AP. The cell surface membrane proteins Cdo and Boc are components and targets of the hedgehog signaling pathway and feedback network in mice. Dev Cell 2006; 10: 647-656.
    • (2006) Dev Cell , vol.10 , pp. 647-656
    • Tenzen, T.1    Allen, B.L.2    Cole, F.3    Kang, J.S.4    Krauss, R.S.5    McMahon, A.P.6
  • 30
    • 45549085493 scopus 로고    scopus 로고
    • Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment
    • Augustine CK, Yoshimoto Y, Gupta M, Zipfel PA, Selim MA, Febbo P et al. Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment. Cancer Res 2008; 68: 3777-3784.
    • (2008) Cancer Res , vol.68 , pp. 3777-3784
    • Augustine, C.K.1    Yoshimoto, Y.2    Gupta, M.3    Zipfel, P.A.4    Selim, M.A.5    Febbo, P.6
  • 31
    • 78650016651 scopus 로고    scopus 로고
    • Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
    • Tanaka H, Kono E, Tran CP, Miyazaki H, Yamashiro J, Shimomura T et al. Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance. Nat Med 2010; 16: 1414-1420.
    • (2010) Nat Med , vol.16 , pp. 1414-1420
    • Tanaka, H.1    Kono, E.2    Tran, C.P.3    Miyazaki, H.4    Yamashiro, J.5    Shimomura, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.