-
1
-
-
42549164807
-
Wnt signalling and its impact on development and cancer
-
A. Klau, and W. Birchmeier Wnt signalling and its impact on development and cancer Nat. Rev. Cancer 8 2008 387 398
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 387-398
-
-
Klau, A.1
Birchmeier, W.2
-
2
-
-
84861986053
-
Wnt/β-catenin signaling and disease
-
H. Clevers, and R. Nusse Wnt/β-catenin signaling and disease Cell 149 2012 1192 1205
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
3
-
-
84861972831
-
Wnt signaling inhibits proteasomal β-catenin degradation within a compositionally intact Axin1 complex
-
V.S. Li, S.S. Ng, P.J. Boersema, T.Y. Low, W.R. Karthaus, J.P. Gerlach, S. Mohammed, A.J. Heck, M.M. Maurice, and T. Mahmoudi Wnt signaling inhibits proteasomal β-catenin degradation within a compositionally intact Axin1 complex Cell 149 2012 1245 1256
-
(2012)
Cell
, vol.149
, pp. 1245-1256
-
-
Li, V.S.1
Ng, S.S.2
Boersema, P.J.3
Low, T.Y.4
Karthaus, W.R.5
Gerlach, J.P.6
Mohammed, S.7
Heck, A.J.8
Maurice, M.M.9
Mahmoudi, T.10
-
4
-
-
79751489596
-
Molecular genetics of colorectal cancer
-
E.R. Fearon Molecular genetics of colorectal cancer Annu. Rev. Pathol. 6 2011 479 507
-
(2011)
Annu. Rev. Pathol.
, vol.6
, pp. 479-507
-
-
Fearon, E.R.1
-
5
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
The Cancer Genome Atlas
-
The Cancer Genome Atlas Comprehensive molecular characterization of human colon and rectal cancer Nature 487 2012 330 337
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
6
-
-
33745532794
-
Genetics of hepatocellular tumors
-
P. Laurent-Puig, and J. Zucman-Rossi Genetics of hepatocellular tumors Oncogene 25 2006 3778 3786
-
(2006)
Oncogene
, vol.25
, pp. 3778-3786
-
-
Laurent-Puig, P.1
Zucman-Rossi, J.2
-
7
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
T. Reya, and H. Clevers Wnt signalling in stem cells and cancer Nature 434 2005 843 850
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
8
-
-
80051926611
-
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
-
W. de Lau, N. Barker, T.Y. Low, B.K. Koo, V.S. Li, H. Teunissen, P. Kujala, A. Haegebarth, P.J. Peters, and M. van de Wetering Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling Nature 476 2011 293 297
-
(2011)
Nature
, vol.476
, pp. 293-297
-
-
De Lau, W.1
Barker, N.2
Low, T.Y.3
Koo, B.K.4
Li, V.S.5
Teunissen, H.6
Kujala, P.7
Haegebarth, A.8
Peters, P.J.9
Van De Wetering, M.10
-
9
-
-
80053560465
-
LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling
-
A. Glinka, C. Dolde, N. Kirsch, Y.L. Huang, O. Kazanskaya, D. Ingelfinger, M. Boutros, C.M. Cruciat, and C. Niehrs LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling EMBO Rep. 12 2011 1055 1061
-
(2011)
EMBO Rep.
, vol.12
, pp. 1055-1061
-
-
Glinka, A.1
Dolde, C.2
Kirsch, N.3
Huang, Y.L.4
Kazanskaya, O.5
Ingelfinger, D.6
Boutros, M.7
Cruciat, C.M.8
Niehrs, C.9
-
10
-
-
79960990066
-
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/b-catenin signaling
-
K.S. Carmon, X. Gong, Q. Lin, A. Thomas, and Q. Liu R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/b-catenin signaling Proc. Natl. Acad. Sci. USA 108 2011 11452 11457
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11452-11457
-
-
Carmon, K.S.1
Gong, X.2
Lin, Q.3
Thomas, A.4
Liu, Q.5
-
11
-
-
84862230930
-
Adult mammalian stem cells: The role of Wnt, Lgr5 and R-spondins
-
J. Schuijers, and H. Clevers Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins EMBO J. 31 2012 2685 2696
-
(2012)
EMBO J.
, vol.31
, pp. 2685-2696
-
-
Schuijers, J.1
Clevers, H.2
-
12
-
-
67349123408
-
Single Lgr5 stem cells build crypt-villus structures in vivo without a mesenchymal niche
-
T. Sato, R.G. Vries, H.J. Snippert, M. van de Wetering, N. Barker, D.E. Stange, J.H. van Es, A. Abo, P. Kujala, and P.J. Peters Single Lgr5 stem cells build crypt-villus structures in vivo without a mesenchymal niche Nature 459 2009 262 265
-
(2009)
Nature
, vol.459
, pp. 262-265
-
-
Sato, T.1
Vries, R.G.2
Snippert, H.J.3
Van De Wetering, M.4
Barker, N.5
Stange, D.E.6
Van Es, J.H.7
Abo, A.8
Kujala, P.9
Peters, P.J.10
-
13
-
-
84860765166
-
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
-
H.X. Hao, Y. Xie, Y. Zhang, O. Charlat, E. Oster, M. Avello, H. Lei, C. Mickanin, D. Liu, and H. Ruffner ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner Nature 485 2012 195 200
-
(2012)
Nature
, vol.485
, pp. 195-200
-
-
Hao, H.X.1
Xie, Y.2
Zhang, Y.3
Charlat, O.4
Oster, E.5
Avello, M.6
Lei, H.7
Mickanin, C.8
Liu, D.9
Ruffner, H.10
-
14
-
-
84865517676
-
Tumour suppressor RNF43 is a stem cell E3 ligase that induces endocytosis of Wnt receptors
-
10.1038/nature11308
-
B.K. Koo, M. Spit, I. Jordens, T.Y. Low, D.E. Stange, M. van de Wetering, J.H. van Es, S. Mohammed, A.J.R. Heck, and M.M. Maurice Tumour suppressor RNF43 is a stem cell E3 ligase that induces endocytosis of Wnt receptors Nature 2012 10.1038/nature11308
-
(2012)
Nature
-
-
Koo, B.K.1
Spit, M.2
Jordens, I.3
Low, T.Y.4
Stange, D.E.5
Van De Wetering, M.6
Van Es, J.H.7
Mohammed, S.8
Heck, A.J.R.9
Maurice, M.M.10
-
15
-
-
84862907854
-
Whole-exosome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of the ubiquitin-dependent pathways
-
J. Wu, Y. Jiao, M. Dal Molin, A. Maitra, R.F. de Wilde, L.D. Wood, J.R. Eshleman, M.G. Goggins, C.L. Wolfgang, and M.I. Canto Whole-exosome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of the ubiquitin-dependent pathways Proc. Natl. Acad. Sci. USA 108 2011 21188 21193
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 21188-21193
-
-
Wu, J.1
Jiao, Y.2
Dal Molin, M.3
Maitra, A.4
De Wilde, R.F.5
Wood, L.D.6
Eshleman, J.R.7
Goggins, M.G.8
Wolfgang, C.L.9
Canto, M.I.10
-
16
-
-
84859757956
-
Whole-exosome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas
-
T. Furukawa, Y. Koboki, E. Tanji, S. Yoshida, T. Hatori, M. Yamamoto, N. Shibata, K. Shimizu, N. Kamatani, and K. Shiratori Whole-exosome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas Sci. Rep. 1 2011 161
-
(2011)
Sci. Rep.
, vol.1
, pp. 161
-
-
Furukawa, T.1
Koboki, Y.2
Tanji, E.3
Yoshida, S.4
Hatori, T.5
Yamamoto, M.6
Shibata, N.7
Shimizu, K.8
Kamatani, N.9
Shiratori, K.10
-
17
-
-
34247854948
-
Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells
-
I. Ivanov, K.C. Lo, L. Hawthorn, J.K. Cowell, and Y. Ionov Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells Oncogene 26 2007 2873 2884
-
(2007)
Oncogene
, vol.26
, pp. 2873-2884
-
-
Ivanov, I.1
Lo, K.C.2
Hawthorn, L.3
Cowell, J.K.4
Ionov, Y.5
-
18
-
-
84861581233
-
Exome sequencing of liver fluke-associated cholangiocarcinoma
-
C.K. Ong, C. Subimerb, C. Pairojkul, S. Wongkham, I. Cutcutache, W. Yu, J.R. McPherson, G.E. Allen, C.C. Ng, and B.H. Wong Exome sequencing of liver fluke-associated cholangiocarcinoma Nat. Genet. 44 2012 690 693
-
(2012)
Nat. Genet.
, vol.44
, pp. 690-693
-
-
Ong, C.K.1
Subimerb, C.2
Pairojkul, C.3
Wongkham, S.4
Cutcutache, I.5
Yu, W.6
McPherson, J.R.7
Allen, G.E.8
Ng, C.C.9
Wong, B.H.10
-
19
-
-
7944230668
-
An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
-
A. Bafico, G. Liu, L. Goldin, V. Harris, and S.A. Aaronson An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells Cancer Cell 6 2004 497 506
-
(2004)
Cancer Cell
, vol.6
, pp. 497-506
-
-
Bafico, A.1
Liu, G.2
Goldin, L.3
Harris, V.4
Aaronson, S.A.5
-
20
-
-
79955964176
-
High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene CDC25A
-
S. Vijayakumar, G. Liu, I.A. Rus, S. Yao, Y. Chen, G. Akiri, L. Grumolato, and S.A. Aaronson High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene CDC25A Cancer Cell 19 2011 601 612
-
(2011)
Cancer Cell
, vol.19
, pp. 601-612
-
-
Vijayakumar, S.1
Liu, G.2
Rus, I.A.3
Yao, S.4
Chen, Y.5
Akiri, G.6
Grumolato, L.7
Aaronson, S.A.8
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