Inactivation of Pde8b enhances memory, motor performance, and protects against age-induced motor coordination decay

Genes, Brain and Behavior

Volumn 11, Issue 7, 2012, Pages 837-847

  Tsai, L C L ^a   Chan, G C K ^a   Nangle, S N ^a   Shimizu Albergine, M ^a   Jones, G L ^a   Storm, D R ^a   Beavo, J A ^a   Zweifel, L S ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

cAMP; Contextual fear; Gene expression; Gene knockout; Instrumental conditioning; Learning; Motor coordination; Phosphodiesterase; Spatial memory

Indexed keywords

PHOSPHODIESTERASE; PHOSPHODIESTERASE 8A; PHOSPHODIESTERASE 8B; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CEREBELLUM; CONTROLLED STUDY; COORDINATION DISORDER; CORPUS STRIATUM; FEAR; GENE EXPRESSION; GENE INACTIVATION; HIPPOCAMPUS; INSTRUMENTAL CONDITIONING; MALE; MEMORY DISORDER; MOTOR COORDINATION; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; SPATIAL MEMORY;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; AGE FACTORS; ANIMALS; ANXIETY; BRAIN; CONDITIONING (PSYCHOLOGY); FEAR; GENE EXPRESSION; MALE; MEMORY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY;

MUS;

EID: 84867336417     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2012.00836.x     Document Type: Article

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