Impaired appetitively as well as aversively motivated behaviors and learning in PDE10A-deficient mice suggest a role for striatal signaling in evaluative salience attribution

Neurobiology of Learning and Memory

Volumn 95, Issue 3, 2011, Pages 260-269

  Piccart, Elisabeth ^a   Gantois, Ilse ^a   Laeremans, Annelies ^a   de Hoogt, Ronald ^b   Meert, Theo ^a,b   Vanhoof, Greet ^b   Arckens, Lutgarde ^a   D'Hooge, Rudi ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Appetitive; Conditioning; Immediate early gene; Morris water maze; PDE10A; Reward motivated behavior; Striatum; Zif268

Indexed keywords

PHOSPHODIESTERASE; PHOSPHODIESTERASE XA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR CINGULATE; ANXIETY; APPETITE; ARTICLE; AVERSION; BEHAVIOR CHANGE; BRAIN NERVE CELL; CONDITIONING; CONTROLLED STUDY; CORPUS STRIATUM; EXPLORATORY BEHAVIOR; GENE EXPRESSION; IMMEDIATE EARLY GENE; LEARNING; MAZE TEST; MEDIUM SPINY NEURON; MOTIVATION; MOUSE; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NONHUMAN; PASSIVE AVOIDANCE; REWARD; SOCIAL BEHAVIOR; SPATIAL LEARNING; SPATIAL MEMORY; TASK PERFORMANCE; ZIF268 GENE;

ANALYSIS OF VARIANCE; ANIMALS; APPETITIVE BEHAVIOR; ASSOCIATION LEARNING; AVOIDANCE LEARNING; CONDITIONING, OPERANT; DISCRIMINATION (PSYCHOLOGY); EARLY GROWTH RESPONSE PROTEIN 1; EXPLORATORY BEHAVIOR; GYRUS CINGULI; MALE; MAZE LEARNING; MICE; MICE, KNOCKOUT; NEOSTRIATUM; PHOSPHORIC DIESTER HYDROLASES; SOCIAL BEHAVIOR; STATISTICS, NONPARAMETRIC;

EID: 79952626137     PISSN: 10747427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nlm.2010.11.018     Document Type: Article

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