Chronic Gαs signaling in the striatum increases anxiety-related behaviors independent of developmental effects

Journal of Neuroscience

Volumn 28, Issue 51, 2008, Pages 13952-13956

  Favilla, Christopher ^a   Abel, Ted ^a   Kelly, Michele P ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b PFIZER INC   (United States)

Author keywords

Anxiety; cAMP; GNAS; L VGCC; Panic disorder; Striatum

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IIALPHA; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; UNCLASSIFIED DRUG; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ACOUSTIC REFLEX; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN DEVELOPMENT; BRAIN LEVEL; BRAIN NERVE CELL; CONDITIONING; CONTROLLED STUDY; CORPUS STRIATUM; FEAR; FOREBRAIN; GENE EXPRESSION; LATENT PERIOD; MAZE TEST; MOUSE; NEWBORN; NONHUMAN; OPEN FIELD BEHAVIOR; OPEN FIELD TEST; PHENOTYPE; POSTNATAL DEVELOPMENT; PREPULSE INHIBITION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STARTLE REFLEX; ANIMAL; ANIMAL BEHAVIOR; BEHAVIOR; GENETICS; METABOLISM; PHYSIOLOGY; SECOND MESSENGER; TRANSGENIC MOUSE;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; CORPUS STRIATUM; CYCLIC AMP; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; MICE; MICE, TRANSGENIC; PROSENCEPHALON; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; SPATIAL BEHAVIOR;

EID: 58149394413     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4986-08.2008     Document Type: Article

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