Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects

PLoS Genetics

Volumn 7, Issue 11, 2011, Pages

  Grossman, Tamar R ^a   Gamliel, Amir ^b   Wessells, Robert J ^c   Taghli Lamallem, Ouarda ^d   Jepsen, Kristen ^b   Ocorr, Karen ^d   Korenberg, Julie R ^e   Peterson, Kirk L ^b   Rosenfeld, Michael G ^b   Bodmer, Rolf ^d   Bier, Ethan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d BURNHAM INSTITUTE   (United States)

^e The Brain Institute at the University of Utah   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COL6A2 GENE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DISEASE SEVERITY; DROSOPHILA; DSCAM GENE; EMBRYO; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENE INTERACTION; GENE OVEREXPRESSION; HEART ATRIUM SEPTUM DEFECT; HEART FAILURE; HEART MUSCLE CELL; HEART RHYTHM; HEART VENTRICLE HYPERTROPHY; MORTALITY; MOUSE; NONHUMAN; STRESS; ANIMAL; CELL ADHESION; CELL LINE; CHROMOSOME 21; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; HEART; HEART MUSCLE; HISTOLOGY; HUMAN; METABOLISM; MULTIFACTORIAL INHERITANCE; PHENOTYPE; PHYSIOLOGY; TRANSGENIC MOUSE;

MAMMALIA; MUS;

CELL ADHESION MOLECULE; COL6A2 PROTEIN, HUMAN; COLLAGEN TYPE 6; DROSOPHILA PROTEIN; DSCAM PROTEIN, DROSOPHILA; DSCAM PROTEIN, HUMAN; DSCAM PROTEIN, MOUSE;

ANIMALS; CELL ADHESION; CELL ADHESION MOLECULES; CELL LINE; CHROMOSOMES, HUMAN, PAIR 21; COLLAGEN TYPE VI; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; HEART; HEART DEFECTS, CONGENITAL; HUMANS; MICE; MICE, TRANSGENIC; MULTIFACTORIAL INHERITANCE; MYOCARDIUM; PHENOTYPE;

EID: 81755187305     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002344     Document Type: Article

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