Effects of macelignan isolated from Myristica fragrans (nutmeg) on expression of matrix metalloproteinase-1 and type I procollagen in UVB-irradiated human skin fibroblasts

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 10, 2012, Pages 1669-1675

  Lee, Kyung Eun ^a   Mun, Sukyeong ^a   Pyun, Hee Bong ^a   Kim, Myung Suk ^a   Hwang, Jae Kwan ^a  

^a Yonsei University   (South Korea)

Author keywords

Macelignan; Matrix metalloproteinase 1; Mitogen activated protein kinase; Reactive oxygen species; Type I procollagen; UV irradiation

Indexed keywords

DICHLOROFLUORESCEIN; HERBACEOUS AGENT; INTERSTITIAL COLLAGENASE; LIGNAN DERIVATIVE; MACELIGNAN; MITOGEN ACTIVATED PROTEIN KINASE; PROCOLLAGEN; REACTIVE OXYGEN METABOLITE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; DRUG MECHANISM; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; NUTMEG; PHOTOAGING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN FIBROBLAST; ULTRAVIOLET B RADIATION; WESTERN BLOTTING;

CELL LINE; CELL SURVIVAL; COLLAGEN TYPE I; FIBROBLASTS; HUMANS; LIGNANS; MATRIX METALLOPROTEINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; MYRISTICA FRAGRANS; PROTECTIVE AGENTS; RNA, MESSENGER; SKIN; ULTRAVIOLET RAYS;

EID: 84867271749     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00037     Document Type: Article

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