Analysis of the humoral immune responses among cynomolgus macaque naturally infected with Reston virus during the 1996 outbreak in the Philippines

BMC Veterinary Research

Volumn 8, Issue , 2012, Pages

  Taniguchi, Satoshi ^a,b   Sayama, Yusuke ^a,c   Nagata, Noriyo ^a   Ikegami, Tetsuro ^d   Miranda, Mary E ^e   Watanabe, Shumpei ^a   Iizuka, Itoe ^a,f   Fukushi, Shuetsu ^a   Mizutani, Tetsuya ^a   Ishii, Yoshiyuki ^b   Saijo, Masayuki ^a   Akashi, Hiroomi ^b   Yoshikawa, Yasuhiro ^b   Kyuwa, Shigeru ^b   Morikawa, Shigeru ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d University of Texas Medical Branch School of Medicine   (United States)

^e Veterinary Public Health Specialist   (Philippines)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

Antibody; Cynomolgus macaque; Cytokine; Ebola; Ebolavirus; Filovirus; Humoral immune response; Reston ebolavirus; Reston virus; Zoonosis

Indexed keywords

EBOLA VIRUS; MACACA; MARBURGVIRUS; PRIMATES; RESTON EBOLAVIRUS; VESICULAR STOMATITIS VIRUS;

NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS ANTIGEN;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; EBOLA VIRUS; EPIDEMIC; HUMORAL IMMUNITY; IMMUNOLOGY; MACACA FASCICULARIS; MONKEY DISEASE; PHILIPPINES; VIREMIA; VIROLOGY;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; DISEASE OUTBREAKS; EBOLAVIRUS; IMMUNITY, HUMORAL; MACACA FASCICULARIS; MONKEY DISEASES; PHILIPPINES; VIREMIA;

EID: 84867236190     PISSN: None     EISSN: 17466148     Source Type: Journal    
DOI: 10.1186/1746-6148-8-189     Document Type: Article

References (30)

1. Kuhn JH, Becker S, Ebihara H, Geisbert TW, Jahrling PB, Kawaoka Y, Netesov SV, Nichol ST, Peters CJ, Volchkov VE, Ksiazek TG. Family _filoviridae. Virus taxonomy - ninth report of the international committee on taxonomy of viruses 2011, 665-671. London, United Kingdom: Elsevier/Academic Press, King Andrew MQ, Adams Michael J, Carstens Eric B, Lefkowitz Elliot J.
2. Morikawa S, Saijo M, Kurane I. Current knowledge on lower virulence of Reston Ebola virus (in French: connaissances actuelles sur la moindre virulence du virus Ebola Reston). Comp Immunol Microbiol Infect Dis 2007, 30(5-6):391-398.
3. Ikegami T, Miranda ME, Calaor AB, Manalo DL, Miranda NJ, Niikura M, Saijo M, Une Y, Nomura Y, Kurane I, et al. Histopathology of natural Ebola virus subtype Reston infection in cynomolgus macaques during the Philippine outbreak in 1996. Exp Anim 2002, 51(5):447-455. 10.1538/expanim.51.447, 12451705.
4. Miranda ME, Miranda NL. Reston ebolavirus in humans and animals in the Philippines: a review. J Infect Dis 2011, 204(Suppl 3):S757-S760. 10.1093/infdis/jir296, 22175070.
5. Barrette RW, Metwally SA, Rowland JM, Xu L, Zaki SR, Nichol ST, Rollin PE, Towner JS, Shieh WJ, Batten B, et al. Discovery of swine as a host for the Reston ebolavirus. Science 2009, 325(5937):204-206. 10.1126/science.1172705, 19590002.
6. Saijo M, Niikura M, Morikawa S, Ksiazek TG, Meyer RF, Peters CJ, Kurane I. Enzyme-linked immunosorbent assays for detection of antibodies to Ebola and Marburg viruses using recombinant nucleoproteins. J Clin Microbiol 2001, 39(1):1-7. 10.1128/JCM.39.1.1-7.2001, 87670, 11136739.
7. Ikegami T, Saijo M, Niikura M, Miranda ME, Calaor AB, Hernandez M, Manalo DL, Kurane I, Yoshikawa Y, Morikawa S. Immunoglobulin G enzyme-linked immunosorbent assay using truncated nucleoproteins of Reston Ebola virus. Epidemiol Infect 2003, 130(3):533-539. 2869991, 12825739.
8. Ikegami T, Saijo M, Niikura M, Miranda ME, Calaor AB, Hernandez M, Manalo DL, Kurane I, Yoshikawa Y, Morikawa S. Development of an immunofluorescence method for the detection of antibodies to ebola virus subtype Reston by the use of recombinant nucleoprotein-expressing HeLa cells. Microbiol Immunol 2002, 46(9):633-638.
9. Baize S, Leroy EM, Georges-Courbot MC, Capron M, Lansoud-Soukate J, Debre P, Fisher-Hoch SP, McCormick JB, Georges AJ. Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in ebola virus-infected patients. Nat Med 1999, 5(4):423-426. 10.1038/7422, 10202932.
10. Wauquier N, Becquart P, Padilla C, Baize S, Leroy EM. Human fatal Zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis. PLoS Negl Trop Dis 2010, 4(10):e837. 10.1371/journal.pntd.0000837, 2950153, 20957152.
11. Ebihara H, Rockx B, Marzi A, Feldmann F, Haddock E, Brining D, Lacasse RA, Gardner D, Feldmann H. Host response dynamics following lethal infection of Rhesus macaques with Zaire ebolavirus. J Infect Dis 2011, 204(Suppl 3):S991-S999. 10.1093/infdis/jir336, 3189992, 21987781.
12. Leroy EM, Baize S, Volchkov VE, Fisher-Hoch SP, Georges-Courbot MC, Lansoud-Soukate J, Capron M, Debre P, McCormick JB, Georges AJ. Human asymptomatic ebola infection and strong inflammatory response. Lancet 2000, 355(9222):2210-2215. 10.1016/S0140-6736(00)02405-3, 10881895.
13. Gupta M, MacNeil A, Reed ZD, Rollin PE, Spiropoulou CF. Serology and cytokine profiles in patients infected with the newly discovered Bundibugyo ebolavirus. Virology 2012, 423(2):119-124. 10.1016/j.virol.2011.11.027, 22197674.
14. Hutchinson KL, Villinger F, Miranda ME, Ksiazek TG, Peters CJ, Rollin PE. Multiplex analysis of cytokines in the blood of cynomolgus macaques naturally infected with ebola virus (Reston serotype). J Med Virol 2001, 65(3):561-566. 10.1002/jmv.2073, 11596094.
15. Ikegami T, Niikura M, Saijo M, Miranda ME, Calaor AB, Hernandez M, Acosta LP, Manalo DL, Kurane I, Yoshikawa Y, et al. Antigen capture enzyme-linked immunosorbent assay for specific detection of Reston ebola virus nucleoprotein. Clin Diagn Lab Immunol 2003, 10(4):552-557. 164255, 12853385.
16. Taniguchi S, Watanabe S, Masangkay JS, Omatsu T, Ikegami T, Alviola P, Ueda N, Iha K, Fujii H, Ishii Y, et al. Reston ebolavirus antibodies in bats, the Philippines. Emerg Infect Dis 2011, 17(8):1559-1560. 3381561, 21801651.
17. Sayama Y, Demetria C, Saito M, Azul RR, Taniguchi S, Fukushi S, Yoshikawa T, Iizuka I, Mizutani T, Kurane I, et al. A seroepidemiologic study of Reston ebolavirus in swine in the Philippines. BMC Vet Res 2012, 8:82. 10.1186/1746-6148-8-82, 3433389, 22709971.
18. Rollin PE, Williams RJ, Bressler DS, Pearson S, Cottingham M, Pucak G, Sanchez A, Trappier SG, Peters RL, Greer PW, et al. Ebola (subtype Reston) virus among quarantined nonhuman primates recently imported from the Philippines to the United States. J Infect Dis 1999, 179(Suppl 1):S108-S114.
19. Hensley LE, Young HA, Jahrling PB, Geisbert TW. Proinflammatory response during ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily. Immunol Lett 2002, 80(3):169-179. 10.1016/S0165-2478(01)00327-3, 11803049.
20. Baize S, Leroy EM, Georges AJ, Georges-Courbot MC, Capron M, Bedjabaga I, Lansoud-Soukate J, Mavoungou E. Inflammatory responses in ebola virus-infected patients. Clin Exp Immunol 2002, 128(1):163-168. 10.1046/j.1365-2249.2002.01800.x, 1906357, 11982604.
21. Wilson JA, Hevey M, Bakken R, Guest S, Bray M, Schmaljohn AL, Hart MK. Epitopes involved in antibody-mediated protection from ebola virus. Science 2000, 287(5458):1664-1666. 10.1126/science.287.5458.1664, 10698744.
22. Prehaud C, Hellebrand E, Coudrier D, Volchkov VE, Volchkova VA, Feldmann H, Le Guenno B, Bouloy M. Recombinant ebola virus nucleoprotein and glycoprotein (Gabon 94 strain) provide new tools for the detection of human infections. J Gen Virol 1998, 79(Pt 11):2565-2572.
23. Volchkov VE, Volchkova VA, Slenczka W, Klenk HD, Feldmann H. Release of viral glycoproteins during ebola virus infection. Virology 1998, 245(1):110-119. 10.1006/viro.1998.9143, 9614872.
24. Sanchez A, Lukwiya M, Bausch D, Mahanty S, Sanchez AJ, Wagoner KD, Rollin PE. Analysis of human peripheral blood samples from fatal and nonfatal cases of ebola (Sudan) hemorrhagic fever: cellular responses, virus load, and nitric oxide levels. J Virol 2004, 78(19):10370-10377. 10.1128/JVI.78.19.10370-10377.2004, 516433, 15367603.
25. Bray M, Geisbert TW. Ebola virus: the role of macrophages and dendritic cells in the pathogenesis of ebola hemorrhagic fever. Int J Biochem Cell Biol 2005, 37(8):1560-1566. 10.1016/j.biocel.2005.02.018, 15896665.
26. Bray M, Mahanty S. Ebola hemorrhagic fever and septic shock. J Infect Dis 2003, 188(11):1613-1617. 10.1086/379727, 14639530.
27. Miranda ME, Ksiazek TG, Retuya TJ, Khan AS, Sanchez A, Fulhorst CF, Rollin PE, Calaor AB, Manalo DL, Roces MC, et al. Epidemiology of ebola (subtype Reston) virus in the Philippines, 1996. J Infect Dis 1999, 179(Suppl 1):S115-S119.
28. Ikegami T, Calaor AB, Miranda ME, Niikura M, Saijo M, Kurane I, Yoshikawa Y, Morikawa S. Genome structure of ebola virus subtype Reston: differences among ebola subtypes. Brief report. Arch Virol 2001, 146(10):2021-2027. 10.1007/s007050170049, 11722021.
29. Fukushi S, Mizutani T, Saijo M, Matsuyama S, Miyajima N, Taguchi F, Itamura S, Kurane I, Morikawa S. Vesicular stomatitis virus pseudotyped with severe acute respiratory syndrome coronavirus spike protein. J Gen Virol 2005, 86(Pt 8):2269-2274.
30. Saijo M, Ami Y, Suzaki Y, Nagata N, Iwata N, Hasegawa H, Ogata M, Fukushi S, Mizutani T, Sata T, et al. LC16m8, A highly attenuated vaccinia virus vaccine lacking expression of the membrane protein B5R, protects monkeys from monkeypox. J Virol 2006, 80(11):5179-5188. 10.1128/JVI.02642-05, 1472157, 16698998.