Malaria Parasite Signal Peptide Peptidase is an ER-Resident Protease Required for Growth but not for Invasion

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Volumn 13, Issue 11, 2012, Pages 1457-1465

  Marapana, Danushka S ^a   Wilson, Danny W ^a,b   Zuccala, Elizabeth S ^a,b   Dekiwadia, Chaitali D ^c   Beeson, James G ^d   Ralph, Stuart A ^c   Baum, Jake ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d MACFARLANE BURNET INSTITUTE FOR MEDICAL RESEARCH AND PUBLIC HEALTH   (Australia)

Author keywords

Endoplasmic reticulum; Gamma secretase; Malaria; Merozoite; Microneme; Plasmodium falciparum; Presenilin; Signal peptide peptidase; Tight junction

Indexed keywords

(TERT BUTOXYCARBONYLAMINO) 6 PHENYLHYDROXYBENZYLHEXANOYLLEUCYLPHENYLALANINAMIDE; 1,3 DI(N CARBOXYBENZOYLLEUCYLLEUCYL)AMINOACETONE; 3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 1 PROPANESULFONIC ACID; ANTIMALARIAL AGENT; ARTESUNATE; CHLOROQUINE; ERYTHROCYTE BAND 3 PROTEIN; HEPARIN; L 685458; PRESENILIN; SIGNAL PEPTIDASE; UNCLASSIFIED DRUG;

ARTICLE; CELL INVASION; CONTROLLED STUDY; DRUG TARGETING; ENDOPLASMIC RETICULUM; ENZYME LOCALIZATION; ERYTHROCYTE; HUMAN; HUMAN CELL; MALARIA; NONHUMAN; PARASITE DEVELOPMENT; PARASITE VIRULENCE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; ENDOPLASMIC RETICULUM; ERYTHROCYTES; HUMANS; MEROZOITES; PLASMODIUM FALCIPARUM; PROTEASE INHIBITORS;

EID: 84867234351     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2012.01402.x     Document Type: Article

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