CASE Plots for the Chemotype-Based Activity and Selectivity Analysis: A CASE Study of Cyclooxygenase Inhibitors

Chemical Biology and Drug Design

Volumn 80, Issue 5, 2012, Pages 752-762

  Pérez Villanueva, Jaime ^a   Medina Franco, José L ^b   Méndez Lucio, Oscar ^c   Yoo, Jakyung ^b   Soria Arteche, Olivia ^a   Izquierdo, Teresa ^a   Lozada, M Concepción ^a   Castillo, Rafael ^c  

^a DEPARTAMENTO DE SISTEMAS BIOLÓGICOS   (Mexico)

^b TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Chemotypes; Cyclooxygenases; Dual activity difference maps; Selectivity; Structure activity relationships; Visualization

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; PROSTAGLANDIN SYNTHASE INHIBITOR;

ARTICLE; CHEMOTYPE ACTIVITY AND SELECTIVITY ENRICHMENT PLOT; PLOTS AND CURVES; PRIORITY JOURNAL; PROCESS DESIGN; STRUCTURE ACTIVITY RELATION;

COMPUTER-AIDED DESIGN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DATABASES, PHARMACEUTICAL; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84867231295     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12019     Document Type: Article

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