Navigating structure-activity landscapes

Drug Discovery Today

Volumn 14, Issue 13-14, 2009, Pages 698-705

  Bajorath, Jürgen ^a   Peltason, Lisa ^a   Wawer, Mathias ^a   Guha, Rajarshi ^b   Lajiness, Michael S ^c   Van Drie, John H ^d  

^a UNIVERSITY OF BONN   (Germany)

^b INDIANA UNIVERSITY   (United States)

^c ELI LILLY AND COMPANY   (United States)

^d Van Drie Research LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A INHIBITOR; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; CHOLINESTERASE INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; ELASTASE INHIBITOR; LIPOXYGENASE INHIBITOR; PHOSPHODIESTERASE IV INHIBITOR; PHOSPHODIESTERASE V INHIBITOR; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEINASE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SQUALENE SYNTHASE INHIBITOR; THROMBIN INHIBITOR;

ANALYTIC METHOD; DRUG POTENCY; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; HIGH THROUGHPUT SCREENING; MATHEMATICAL ANALYSIS; MATHEMATICAL COMPUTING; MATHEMATICAL PARAMETERS; MOLECULAR MODEL; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; HUMANS; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67649341994     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2009.04.003     Document Type: Review

References (18)

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