메뉴 건너뛰기




Volumn 33, Issue 10, 2012, Pages 1277-1284

Bovine lactoferrin improves bone mass and microstructure in ovariectomized rats via OPG/RANKL/RANK pathway

Author keywords

bone; bone mineral density; bone turnover; lactoferrin; OPG RANKL RANK pathway

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; COLLAGEN TYPE 1 TELOPEPTIDE; ESTRADIOL; LACTOFERRIN; MESSENGER RNA; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; UNCLASSIFIED DRUG;

EID: 84867203022     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.83     Document Type: Article
Times cited : (75)

References (30)
  • 3
    • 0028783576 scopus 로고
    • The effect of ovariectomy on bone metabolism in rats
    • Omi N, Ezawa I. The effect of ovariectomy on bone metabolism in rats. Bone 1995; 17: 163S-168S.
    • (1995) Bone , vol.17
    • Omi, N.1    Ezawa, I.2
  • 4
  • 5
    • 0029130333 scopus 로고
    • Lactoferrin: Molecular structure and biological function
    • Lonnerdal B, Iyer S. Lactoferrin: molecular structure and biological function. Annu Rev Nutr 1995; 15: 93-110.
    • (1995) Annu Rev Nutr , vol.15 , pp. 93-110
    • Lonnerdal, B.1    Iyer, S.2
  • 6
    • 28344447990 scopus 로고    scopus 로고
    • Multifunctional roles of lactoferrin: A critical overview
    • Ward PP, Paz E, Conneely OM. Multifunctional roles of lactoferrin: a critical overview. Cell Mol Life Sci 2005; 62: 2540-8.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 2540-2548
    • Ward, P.P.1    Paz, E.2    Conneely, O.M.3
  • 8
    • 4344694236 scopus 로고    scopus 로고
    • Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo
    • Cornish J, Callon KE, Naot D, Palmano KP, Banovic T, Bava U, et al. Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo. Endocrinology 2004; 145: 4366-74.
    • (2004) Endocrinology , vol.145 , pp. 4366-4374
    • Cornish, J.1    Callon, K.E.2    Naot, D.3    Palmano, K.P.4    Banovic, T.5    Bava, U.6
  • 9
    • 4544317903 scopus 로고    scopus 로고
    • The low-density lipoprotein receptor-related protein 1 is a mitogenic receptor for lactoferrin in osteoblastic cells
    • Grey A, Banovic T, Zhu Q, Watson M, Callon K, Palmano K, et al. The low-density lipoprotein receptor-related protein 1 is a mitogenic receptor for lactoferrin in osteoblastic cells. Mol Endocrinol 2004; 18: 2268-78.
    • (2004) Mol Endocrinol , vol.18 , pp. 2268-2278
    • Grey, A.1    Banovic, T.2    Zhu, Q.3    Watson, M.4    Callon, K.5    Palmano, K.6
  • 10
    • 33646550545 scopus 로고    scopus 로고
    • Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathway
    • Grey A, Zhu Q, Watson M, Callon K, Cornish J. Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathway. Mol Cell Endocrinol 2006; 251: 96-102.
    • (2006) Mol Cell Endocrinol , vol.251 , pp. 96-102
    • Grey, A.1    Zhu, Q.2    Watson, M.3    Callon, K.4    Cornish, J.5
  • 12
    • 60949099012 scopus 로고    scopus 로고
    • Effect of lactoferrin-embedded collagen membrane on osteogenic differentiation of human osteoblast-like cells
    • Takayama Y, Mizumachi K. Effect of lactoferrin-embedded collagen membrane on osteogenic differentiation of human osteoblast-like cells. J Biosci Bioeng 2009; 107: 191-5.
    • (2009) J Biosci Bioeng , vol.107 , pp. 191-195
    • Takayama, Y.1    Mizumachi, K.2
  • 14
    • 65349196069 scopus 로고    scopus 로고
    • Orally administered lactoferrin preserves bone mass and microarchitecture in ovariectomized rats
    • Guo HY, Jiang L, Ibrahim SA, Zhang L, Zhang H, Zhang M, et al. Orally administered lactoferrin preserves bone mass and microarchitecture in ovariectomized rats. J Nutr 2009; 139: 958-64.
    • (2009) J Nutr , vol.139 , pp. 958-964
    • Guo, H.Y.1    Jiang, L.2    Ibrahim, S.A.3    Zhang, L.4    Zhang, H.5    Zhang, M.6
  • 15
    • 68949212053 scopus 로고    scopus 로고
    • Milk ribonuclease-enriched-lactoferrin induces positive effects on bone turnovermarkers in postmenopausal women
    • Bharadwaj S, Naidu AG, Betageri GV, Prasadarao NV, Naidu AS. Milk ribonuclease-enriched-lactoferrin induces positive effects on bone turnovermarkers in postmenopausal women. Osteoporos Int 2009; 20: 1603-11.
    • (2009) Osteoporos Int , vol.20 , pp. 1603-1611
    • Bharadwaj, S.1    Naidu, A.G.2    Betageri, G.V.3    Prasadarao, N.V.4    Naidu, A.S.5
  • 16
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature 2003; 423: 337-42.
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 17
    • 79958125251 scopus 로고    scopus 로고
    • Current and emerging therapies for osteoporosis
    • Mitchner NA, Harris ST. Current and emerging therapies for osteoporosis. J Fam Pract 2009; 58: S45-9.
    • (2009) J Fam Pract , vol.58
    • Mitchner, N.A.1    Harris, S.T.2
  • 20
    • 0028925088 scopus 로고
    • Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis
    • Manolagos SC, Jilka RL. Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. N Engl J Med 1995; 332: 305-11.
    • (1995) N Engl J Med , vol.332 , pp. 305-311
    • Manolagos, S.C.1    Jilka, R.L.2
  • 22
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-9.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 24
    • 26844574658 scopus 로고    scopus 로고
    • Runx2: A master organizer of gene transcription in developing and maturing osteoblasts
    • Schroeder TM, Jensen ED, Westendorf JJ. Runx2: a master organizer of gene transcription in developing and maturing osteoblasts. Birth Defects Res C Embryo Today 2005; 75: 213-25.
    • (2005) Birth Defects Res C Embryo Today , vol.75 , pp. 213-225
    • Schroeder, T.M.1    Jensen, E.D.2    Westendorf, J.J.3
  • 25
    • 42749092987 scopus 로고    scopus 로고
    • Transcription factors controlling osteoblastogenesis
    • Marie PJ. Transcription factors controlling osteoblastogenesis. Arch Biochem Biophys 2008; 473: 98-105.
    • (2008) Arch Biochem Biophys , vol.473 , pp. 98-105
    • Marie, P.J.1
  • 26
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998; 93: 165-76.
    • (1998) Cell , vol.93 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.L.3    Kelley, M.J.4    Dunstan, C.R.5    Burgess, T.6
  • 27
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, Capparelli C, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999; 397: 315-23.
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.Y.1    Yoshida, H.2    Sarosi, I.3    Tan, H.L.4    Timms, E.5    Capparelli, C.6
  • 28
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
    • Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang MS, Lüthy R, et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997; 89: 309-19.
    • (1997) Cell , vol.89 , pp. 309-319
    • Simonet, W.S.1    Lacey, D.L.2    Dunstan, C.R.3    Kelley, M.4    Chang, M.S.5    Lüthy, R.6
  • 30


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.