In vitro and in vivo Antitumor Activity of Doxorubicin-Loaded Alginic-Acid-Based Nanoparticles

Macromolecular Bioscience

Volumn 12, Issue 10, 2012, Pages 1326-1335

  Cheng, Yuan ^a   Yu, Shuling ^a   Wang, Jingjing ^a   Qian, Hanqing ^a   Wu, Wei ^a   Jiang, Xiqun ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Alginic acid; Antitumor; Drug delivery; Nanoparticles; Self assembly

Indexed keywords

ALGINIC ACID; ANTI-TUMOR ACTIVITIES; ANTI-TUMOR EFFICACY; ANTI-TUMORS; EPR EFFECT; ETHYL METHACRYLATES; FLUORESCENCE IMAGING; IN-VITRO; IN-VIVO; LOW TOXICITY; SPHERICAL MORPHOLOGIES; TUMOR AREAS; TUMOR GROWTH;

DRUG DELIVERY; MAMMALS; SELF ASSEMBLY; TUMORS;

NANOPARTICLES;

ALGINIC ACID; DOXORUBICIN; NANOPARTICLE; POLY[2 (DIMETHYLAMINO)ETHYL METHACRYLATE];

ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BODY WEIGHT; CANCER CHEMOTHERAPY; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG PENETRATION; DRUG RELEASE; DRUG RETENTION; FLUORESCENCE IMAGING; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MORPHOLOGY; MOUSE; NEAR INFRARED SPECTROSCOPY; NONHUMAN; PARTICLE SIZE; PH; TRANSMISSION ELECTRON MICROSCOPY; TUMOR GROWTH; TUMOR VOLUME; WEIGHT REDUCTION;

ALGINATES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL SURVIVAL; DOXORUBICIN; DRUG CARRIERS; DRUG COMPOUNDING; FLUORESCENT DYES; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED ICR; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; NEOPLASM TRANSPLANTATION; OPTICAL IMAGING; PARTICLE SIZE; POLYMETHACRYLIC ACIDS;

MUS;

EID: 84867198271     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201200165     Document Type: Article

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