Protective effect of sauchinone on methamphetamine-induced neurotoxicity in mice

Journal of Pharmacological Sciences

Volumn 118, Issue 4, 2012, Pages 531-536

  Jang, Eun Young ^a   Park, Kyung Ah ^a   Lee, Jong Rock ^a   Yang, Chae Ha ^a   Hwang, Meeyul ^a  

^a Daegu Haany University   (South Korea)

Author keywords

Methamphetamine; Nitric oxide; Sauchinone

Indexed keywords

CD11B ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; METHAMPHETAMINE; NEURONAL NITRIC OXIDE SYNTHASE; NEUROPROTECTIVE AGENT; NITRIC OXIDE; SAUCHINONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL DESIGN; GLIA CELL; MALE; MOLECULAR DYNAMICS; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 84867191045     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.11207SC     Document Type: Article

References (14)

1. Chung BS, Shin MG. Dictionary of Korean folk medicine. Seoul: Young Lim Sa; 1990.
2. Sung SH, Lee EJ, Cho JH, Kim HS, Kim YC. Sauchinone, a lignan from Saururus chinensis, attenuates CCl4-induced toxicity in primary cultures of rat hepatocytes. Biol Pharm Bull. 2006; 23:666-668.
3. Lee AK, Sung SH, Kim YC, Kim SG. Inhibition of lipopolysaccharide- inducible nitric oxide synthase, TNF-α and COX-2 expression by sauchinone effects on I-κ phosphorylation, C/EBP and AP-1 activation. Br J Pharmacol. 2003;139:11-20.
4. Hozumi H, Asanuma M, Miyazaki I, Fukuoka S, Kikkawa Y, Kimoto N, et al. Protective effects of interferon-gamma against methamphetamine-induced neurotoxicity. Toxicol Lett. 2008;177:123-129.
5. Cadet JL, Jayanthi S, Deng X. Speed kills: cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis. FASEB J. 2003;17:1775-1788.
6. Cadet JL. Roles of glutamate, nitric oxide, oxidative stress, and apoptosis in the neurotoxicity of methamphetamine. In: Herman BH, editor. Glutamate and addiction. New Jersey: Humana Press; 2003. p. 83-106.
7. Kuhn DM, Aretha CW, Geddes TJ. Peroxynitrite inactivation of tyrosine hydroxylase: mediation by sulfhydryl oxidation, not tyrosine nitration. J Neurosci. 1999;19:10289-10294.
8. Park SU, Ferrer JV, Javitch JA, Kuhn DM. Peroxynitrite inactivates the human dopamine transporter by modification of cystein 342: potential mechanism of neurotoxicity in dopamine neurons. J Neurosci. 2002;22:4399-4405.
9. LaVoie MJ, Hastings TG. Peroxynitrite- and nitrite-induced oxidation of dopamine: implications for nitric oxide in dopaminergic cell loss. J Neurochem. 1999;73:2546-2554.
10. Sanchez V, Zeini M, Camarero J, O'Shea E, Bosca L, Green AR, et al. The nNOS inhibitor, AR-R17477AR, prevents the loss of NF68 immunoreactivity induced by methamphetamine in the mouse striatum. J Neurochem. 2003;85:515-524.
11. Anderson KL, Itzhak Y. Methamphetamine-induced selective dopaminergic neurotoxicity is accompanied by an incrase in striatal nitrate in the mouse. Ann N Y Acad Sci. 2006;1074:225-233.
12. Stephans SE, Yamamoto BK. Methamphetamine-induced neurotoxicity: roles for glutamate and dopamine efflux. Synapse. 1994;17:203-209.
13. Itzhak Y, Ali SF. The neuronal nitric oxide synthase inhibitior, 7-nitroindazole, proteicts against methamphetamine-induced neurotoxicity in vivo. J Neurochem. 1996;67:1770-1773.
14. Lee MJ, Yang CH, Jeon JP, Hwang M. Protective effects of isoliquiritigenin against methamphetamine-induced neurotoxicity in mice. J Pharmacol Sci. 2009;111:216-220.