MiRNA-218 contributes to the regulation of D-glucuronyl C5-epimerase expression in normal and tumor breast tissues

Epigenetics

Volumn 7, Issue 10, 2012, Pages 1109-1114

  Prudnikova, Tatiana Y ^a   Mostovich, Luydmila A ^a   Kashuba, Vladimir I ^b,c   Ernberg, Ingemar ^c   Zabarovsky, Eugene R ^c,d   Grigorieva, Elvira V ^a,c  

^a INSTITUTE OF MOLECULAR BIOLOGY AND BIOPHYSICS   (Russian Federation)

^b INSTITUTE OF MOLECULAR BIOLOGY AND GENETICS   (Ukraine)

^c KAROLINSKA INSTITUTE   (Sweden)

^d LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Biosynthesis; Breast cancer; D glucuronyl C5 epimerase; Expression; GLCE; Heparan sulphate proteoglycan; miRNA; Tumor suppressor gene

Indexed keywords

DEXTO GLUCURONYL C5 EPIMERASE; EPIMERASE; MICRORNA; MICRORNA 218; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST TUMOR; CELL LEVEL; CELL STRAIN MCF 7; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; ENZYME REGULATION; GENETIC REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; PROTEIN CONTENT; PROTEIN EXPRESSION;

EID: 84867181715     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.22103     Document Type: Article

References (35)

1. Ori A, Wilkinson MC, Fernig DG. The heparanome and regulation of cell function: structures, functions and challenges. Front Biosci 2008; 13:4309-38; PMID:18508513; http://dx.doi.org/10.2741/3007.
2. Sarrazin S, Lamanna WC, Esko JD. Heparan sulfate proteoglycans. Cold Spring Harb Perspect Biol 2011; 3:7; PMID:21690215; http://dx.doi.org/10.1101/cshperspect.a004952.
3. Kim SH, Turnbull J, Guimond S. Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor. J Endocrinol 2011; 209:139-51; PMID:21307119; http://dx.doi. org/10.1530/JOE-10-0377.
4. Malavaki CJ, Theocharis AD, Lamari FN, Kanakis I, Tsegenidis T, Tzanakakis GN, et al. Heparan sulfate: biological significance, tools for biochemical analysis and structural characterization. Biomed Chromatogr 2011; 25:11-20; PMID:21204109; http://dx.doi.org/10.1002/bmc.1536.
5. Prudnikova TY, Mostovich LA, Domanitskaya NV, Pavlova TV, Kashuba VI, Zabarovsky ER, et al. Antiproliferative effect of D-glucuronyl C5-epimerase in human breast cancer cells. Cancer Cell Int 2010; 10:27; PMID:20723247; http://dx.doi.org/10.1186/1475-2867-10-27.
6. Eshchenko TY, Rykova VI, Chernakov AE, Sidorov SV, Grigorieva EV. Expression of different proteoglycans in human breast tumors. Biochemistry (Mosc) 2007; 72:1016-20; PMID:17922662; http://dx.doi. org/10.1134/S0006297907090143.
7. Grigorieva E, Eshchenko T, Rykova VI, Chernakov A, Zabarovsky ER, Sidorov SV. Decreased expression of human D-glucuronyl C5-epimerase in breast cancer. Int J Cancer 2008; 122:1172-6; PMID:17985344; http://dx.doi.org/10.1002/ijc.23203.
8. Ghiselli G, Agrawal A. The human D-glucuronyl C5-epimerase gene is transcriptionally activated through the beta-catenin-TCF4 pathway. Biochem J 2005; 390:493-9; PMID:15853773; http://dx.doi.org/10.1042/BJ20050152.
9. Small EM, Sutherland LB, Rajagopalan KN, Wang S, Olson EN. MicroRNA-218 regulates vascular patterning by modulation of Slit-Robo signaling. Circ Res 2010; 107:1336-44; PMID:20947829; http://dx.doi.org/10.1161/CIRCRESAHA.110.227926.
10. Lopes CC, Toma L, Pinhal MA, Porcionatto MA, Sogayar MC, Dietrich CP, et al. EJ-ras oncogene transfection of endothelial cells upregulates the expression of syndecan-4 and downregulates heparan sulfate sulfotransferases and epimerase. Biochimie 2006; 88:1493-504; PMID:16793191; http://dx.doi.org/10.1016/j.biochi.2006.04.009.
11. Mostovich LA, Prudnikova TY, Kondratov AG, Gubanova NV, Kharchenko OA, Kutsenko OS, et al. The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer. Epigenetics 2012; 7:930-9; PMID:22805760; http://dx.doi.org/10.4161/epi.21199.
12. Grigorieva EV, Prudnikova TY, Domanitskaya NV, Mostovich LA, Pavlova TV, Kashuba VI, et al. D-glucuronyl C5-epimerase suppresses small-cell lung cancer cell proliferation in vitro and tumour growth in vivo. Br J Cancer 2011; 105:74-82; PMID:21654676; http://dx.doi.org/10.1038/bjc.2011.170.
13. Davidson MR, Larsen JE, Yang IA, Hayward NK, Clarke BE, Duhig EE, et al. miR-218 is a strong candidate tumour suppressing miRNA potentially involved in lung cancer. PLoS ONE 2010; 5:e12560; PMID:20838434; http://dx.doi.org/10.1371/journal. pone.0012560.
14. Tatarano S, Chiyomaru T, Kawakami K, Enokida H, Yoshino H, Hidaka H, et al. miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer. Int J Oncol 2011; 39:13-21; PMID:21519788.
15. Alajez NM, Lenarduzzi M, Ito E, Hui AB, Shi W, Bruce J, et al. MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway. Cancer Res 2011; 71:2381-91; PMID:21385904; http://dx.doi.org/10.1158/0008-5472.CAN-10-2754.
16. Hidaka H, Seki N, Yoshino H, Yamasaki T, Yamada Y, Nohata N, et al. Tumor suppressive microRNA-1285 regulates novel molecular targets: aberrant expression and functional significance in renal cell carcinoma. Oncotarget 2012; 3:44-57; PMID:22294552.
17. Lages E, Ipas H, Guttin A, Nesr H, Berger F, Issartel JP. MicroRNAs: molecular features and role in cancer. Front Biosci 2012; 17:2508-40; PMID:22652795; http://dx.doi.org/10.2741/4068.
18. Iorio MV, Croce CM. microRNA involvement in human cancer. Carcinogenesis 2012; 33:1126-33; PMID:22491715; http://dx.doi.org/10.1093/carcin/bgs140.
19. Rao SA, Santosh V, Somasundaram K. Genome-wide expression profiling identifies deregulated miRNAs in malignant astrocytoma. Mod Pathol 2010; 23:1404-17; PMID:20711171; http://dx.doi.org/10.1038/modpathol.2010.135.
20. Song L, Huang Q, Chen K, Liu L, Lin C, Dai T, et al. miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β. Biochem Biophys Res Commun 2010; 402:135-40; PMID:20933503; http://dx.doi.org/10.1016/j.bbrc.2010.10.003.
21. Wu DW, Cheng YW, Wang J, Chen CY, Lee H. Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting. Cancer Res 2010; 70:10392-401; PMID:21159652; http://dx.doi.org/10.1158/0008-5472.CAN-10-2341.
22. White NM, Bao TT, Grigull J, Youssef YM, Girgis A, Diamandis M, et al. miRNA profiling for clear cell renal cell carcinoma: biomarker discovery and identification of potential controls and consequences of miRNA dysregulation. J Urol 2011; 186:1077-83; PMID:21784468; http://dx.doi.org/10.1016/j. juro.2011.04.110.
23. Tie J, Pan Y, Zhao L, Wu K, Liu J, Sun S, et al. MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. PLoS Genet 2010; 6:e1000879; PMID:20300657; http://dx.doi.org/10.1371/journal.pgen.1000879.
24. Leite KR, Tomiyama A, Reis ST, Sousa-Canavez JM, Sañudo A, Camara-Lopes LH, et al. MicroRNA expression profiles in the progression of prostate cancer-from high-grade prostate intraepithelial neoplasia to metastasis. Urol Oncol 2011; In press; PMID:21880514.
25. Necela BM, Carr JM, Asmann YW, Thompson EA. Differential expression of microRNAs in tumors from chronically inflamed or genetic (APC(Min/+)) models of colon cancer. PLoS One 2011; 6:e18501; PMID:21532750; http://dx.doi.org/10.1371/journal.pone.0018501.
26. Pasquinelli AE. MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat Rev Genet 2012; 13:271-82; PMID:22411466.
27. Li X, Shen Y, Ichikawa H, Antes T, Goldberg GS. Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration. Oncogene 2009; 28:4272-83; PMID:19767772; http://dx.doi.org/10.1038/onc.2009.278.
28. Uesugi A, Kozaki K, Tsuruta T, Furuta M, Morita K, Imoto I, et al. The tumor suppressive microRNA miR- 218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. Cancer Res 2011; 71:5765-78; PMID:21795477; http://dx.doi.org/10.1158/0008-5472.CAN-11-0368.
29. Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, et al. A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development 2011; 138:1409-19; PMID:21385766; http://dx.doi.org/10.1242/dev.060046.
30. Simion A, Laudadio I, Prévot PP, Raynaud P, Lemaigre FP, Jacquemin P. MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2. Biochem Biophys Res Commun 2010; 391:293-8; PMID:19913497; http://dx.doi.org/10.1016/j.bbrc.2009.11.052.
31. Zhang Y, Xie RL, Croce CM, Stein JL, Lian JB, van Wijnen AJ, et al. A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2. Proc Natl Acad Sci U S A 2011; 108:9863-8; PMID:21628588; http://dx.doi.org/10.1073/pnas.1018493108.
32. Chiyomaru T, Enokida H, Kawakami K, Tatarano S, Uchida Y, Kawahara K, et al. Functional role of LASP1 in cell viability and its regulation by microRNAs in bladder cancer. Urol Oncol 2010; 30:434-43; PMID:20843712.
33. Martinez I, Gardiner AS, Board KF, Monzon FA, Edwards RP, Khan SA. Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells. Oncogene 2008; 27:2575-82; PMID:17998940; http://dx.doi.org/10.1038/sj.onc.1210919.
34. Li Q, Zhu F, Chen P. miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. Biochem Biophys Res Commun 2012; 424:28-33; PMID:22705304; http://dx.doi.org/10.1016/j.bbrc.2012.06.028.
35. Li Z, Huang H, Chen P, He M, Li Y, Arnovitz S, et al. miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLLrearranged leukaemia. Nat Commun 2012; 3:688; PMID:22353710; http://dx.doi.org/10.1038/ncomms1681.