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Volumn 25, Issue 1, 2011, Pages 11-20

Heparan sulfate: Biological significance, tools for biochemical analysis and structural characterization

Author keywords

Alzheimer disease; Cancer; Capillary electrophoresis; Heparan sulfate; Heparin; Structure analysis

Indexed keywords

CAPILLARY ELECTROPHORESIS; DIAGNOSIS; FLUOROPHORES; GLUCOSE; POLYSACCHARIDES; SULFUR COMPOUNDS;

EID: 78650673333     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1536     Document Type: Review
Times cited : (34)

References (81)
  • 1
    • 0026409511 scopus 로고
    • Disaccharide compositional analysis of heparin and heparin sulfate using capillary zone electrophoresis
    • Ampofo SA, Wang HM and Linhardt RJ. Disaccharide compositional analysis of heparin and heparin sulfate using capillary zone electrophoresis. Analytical Biochemistry 1991; 199: 249-255.
    • (1991) Analytical Biochemistry , vol.199 , pp. 249-255
    • Ampofo, S.A.1    Wang, H.M.2    Linhardt, R.J.3
  • 2
    • 77956624954 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: New concepts for heparanase function in tumor progression and metastasis
    • Barash U, Cohen-Kapaln V, Dowek I, Sanderson RD, Ilan N and Vlodavsky I. Proteoglycans in health and disease: New concepts for heparanase function in tumor progression and metastasis. FEBS Journal 2010; 19: 3890-3903.
    • (2010) FEBS Journal , vol.19 , pp. 3890-3903
    • Barash, U.1    Cohen-Kapaln, V.2    Dowek, I.3    Sanderson, R.D.4    Ilan, N.5    Vlodavsky, I.6
  • 3
    • 25144521846 scopus 로고    scopus 로고
    • Quantification of isomers from a mixture of twelve heparin and heparan sulfate disaccharides using tandem mass
    • Behr JR., Matsumoto Y, White FM and Sasisekharan R. Quantification of isomers from a mixture of twelve heparin and heparan sulfate disaccharides using tandem mass. Rapid Communications in Mass Spectrometry 2005; 19: 2553-2562.
    • (2005) Rapid Communications in Mass Spectrometry , vol.19 , pp. 2553-2562
    • Behr, J.R.1    Matsumoto, Y.2    White, F.M.3    Sasisekharan, R.4
  • 6
    • 18044368921 scopus 로고    scopus 로고
    • Selectins facilitate carcinoma metastasis and heparin can prevent them
    • Borsig L. Selectins facilitate carcinoma metastasis and heparin can prevent them. News in Physiological Sciences 2004; 19: 16-21.
    • (2004) News in Physiological Sciences , vol.19 , pp. 16-21
    • Borsig, L.1
  • 8
    • 85164055938 scopus 로고    scopus 로고
    • Chemistry and Biology of Heparin and Heparan Sulphate
    • Garg HG, Linhardt RJ, Hales CA (eds). Elsevier: Oxford,
    • Casu B. Structure and active domains of heparin. In Chemistry and Biology of Heparin and Heparan Sulphate, Garg HG, Linhardt RJ, Hales CA (eds). Elsevier: Oxford, 2005; 1-28.
    • (2005) Structure and active domains of heparin , pp. 1-28
    • Casu, B.1
  • 10
    • 0030725311 scopus 로고    scopus 로고
    • Perlecan binds to the beta-amyloid proteins (Aβ) of Alzheimer's disease, accelerates Aβ fibril formation, and maintains Aβ fibril stability
    • Castillo GM, Ngo C, Cummings J, Wight TN and Snow AD. Perlecan binds to the beta-amyloid proteins (Aβ) of Alzheimer's disease, accelerates Aβ fibril formation, and maintains Aβ fibril stability. Journal of Neurochemistry 1999; 69: 2452-2465.
    • (1999) Journal of Neurochemistry , vol.69 , pp. 2452-2465
    • Castillo, G.M.1    Ngo, C.2    Cummings, J.3    Wight, T.N.4    Snow, A.D.5
  • 11
    • 0028950819 scopus 로고
    • Characterisation by LSI-MS and 1H NMR spectroscopy of tetra-, hexa-, and octa-saccharides of porcine intestinal heparin
    • Chai W, Hounsell EF, Bauer CJ and Lawson AM. Characterisation by LSI-MS and 1H NMR spectroscopy of tetra-, hexa-, and octa-saccharides of porcine intestinal heparin. Carbohydrate Research 1995; 269: 139-156.
    • (1995) Carbohydrate Research , vol.269 , pp. 139-156
    • Chai, W.1    Hounsell, E.F.2    Bauer, C.J.3    Lawson, A.M.4
  • 12
    • 0032523417 scopus 로고    scopus 로고
    • Characterization of heparin oligosaccharide mixtures as ammonium salts using electrospray mass spectrometry
    • Chai W, Luo J, Lim CK and Lawson AM. Characterization of heparin oligosaccharide mixtures as ammonium salts using electrospray mass spectrometry. Analytical Chemistry 1998; 70: 2060-2066.
    • (1998) Analytical Chemistry , vol.70 , pp. 2060-2066
    • Chai, W.1    Luo, J.2    Lim, C.K.3    Lawson, A.M.4
  • 15
    • 0034482080 scopus 로고    scopus 로고
    • Detection and quantification of the sulfated disaccharides in chondroitin sulfate by electrospray tandem mass spectrometry
    • Desaire H and Leary JA. Detection and quantification of the sulfated disaccharides in chondroitin sulfate by electrospray tandem mass spectrometry. Journal of the American Society for Mass Spectrometry 2000, 11: 916-920.
    • (2000) Journal of the American Society for Mass Spectrometry , vol.11 , pp. 916-920
    • Desaire, H.1    Leary, J.A.2
  • 16
    • 0037286285 scopus 로고    scopus 로고
    • Capillary electrophoresis and enzyme solid phase assay for examining the purity of a synthetic heparin proteoglycan-like conjugate and identifying binding to basic fibroblast growth factor
    • Dimitrellos V, Lamari FN, Militsopoulou M, Kanakis I and Karamanos NK. Capillary electrophoresis and enzyme solid phase assay for examining the purity of a synthetic heparin proteoglycan-like conjugate and identifying binding to basic fibroblast growth factor. Biomedical Chromatography 2003; 17: 42-47.
    • (2003) Biomedical Chromatography , vol.17 , pp. 42-47
    • Dimitrellos, V.1    Lamari, F.N.2    Militsopoulou, M.3    Kanakis, I.4    Karamanos, N.K.5
  • 17
    • 0031568286 scopus 로고    scopus 로고
    • Capillary electrophoresis of carboxylated carbohydrates. III. Selective precolumn derivatization of glycosaminoglycan disaccharides with 7-aminonaphthalene-1,3-disulfonic acid fluorescing tag for ultrasensitive laser-induced fluorescence detection
    • El Rassi Z, Postlewait J, Mechref Y and Ostrander GK. Capillary electrophoresis of carboxylated carbohydrates. III. Selective precolumn derivatization of glycosaminoglycan disaccharides with 7-aminonaphthalene-1, 3-disulfonic acid fluorescing tag for ultrasensitive laser-induced fluorescence detection. Analytical Biochemistry 1997; 244: 283-290.
    • (1997) Analytical Biochemistry , vol.244 , pp. 283-290
    • El Rassi, Z.1    Postlewait, J.2    Mechref, Y.3    Ostrander, G.K.4
  • 20
    • 0030669701 scopus 로고    scopus 로고
    • Structure-activity relationship of heparin sulfate
    • Gallagher JT. Structure-activity relationship of heparin sulfate. Biochemical Society Transactions 1997; 25: 1206-1209.
    • (1997) Biochemical Society Transactions , vol.25 , pp. 1206-1209
    • Gallagher, J.T.1
  • 21
    • 0037137477 scopus 로고    scopus 로고
    • Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes
    • Grobe K, Ledin J, Ringvall M, Holmborn K, Forsberg E, Esko JD and Kjellén L. Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes. Biochimica et Biophysica Acta 2002; 1573: 209-215.
    • (2002) Biochimica et Biophysica Acta , vol.1573 , pp. 209-215
    • Grobe, K.1    Ledin, J.2    Ringvall, M.3    Holmborn, K.4    Forsberg, E.5    Esko, J.D.6    Kjellén, L.7
  • 24
    • 0021223523 scopus 로고
    • Separation of radiolabelled glycosaminoglycan oligosaccharides by polyacrylamide-gel electrophoresis
    • Hampson IN and Gallagher JT. Separation of radiolabelled glycosaminoglycan oligosaccharides by polyacrylamide-gel electrophoresis. Biochemical Journal 1984; 221: 697-705.
    • (1984) Biochemical Journal , vol.221 , pp. 697-705
    • Hampson, I.N.1    Gallagher, J.T.2
  • 26
    • 33748683743 scopus 로고    scopus 로고
    • Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis
    • Ilan N, Elkin M and Vlodavsky I. Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis. International Journal of Biochemistry and Cell Biology 2006; 38: 2018-2039.
    • (2006) International Journal of Biochemistry and Cell Biology , vol.38 , pp. 2018-2039
    • Ilan, N.1    Elkin, M.2    Vlodavsky, I.3
  • 27
    • 77956637386 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: emerging concepts and future directions
    • Iozzo RV and Karamanos NK. Proteoglycans in health and disease: emerging concepts and future directions. FEBS Journal 2010; 19: 3863.
    • (2010) FEBS Journal , vol.19 , pp. 3863
    • Iozzo, R.V.1    Karamanos, N.K.2
  • 28
    • 77956621814 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans
    • Iozzo RV and Schaefer L. Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans. FEBS Journal 2010; 19: 3864-3875.
    • (2010) FEBS Journal , vol.19 , pp. 3864-3875
    • Iozzo, R.V.1    Schaefer, L.2
  • 30
    • 0027955924 scopus 로고
    • Determination of 24 variously sulfated galactosaminoglycan- and hyaluronan-derived disaccharides by high-performance liquid chromatography
    • Karamanos NK, Syrokou A, Vanky P, Nurminen M and Hjerpe A. Determination of 24 variously sulfated galactosaminoglycan- and hyaluronan-derived disaccharides by high-performance liquid chromatography. Analytical Biochemistry 1994; 221: 189-199.
    • (1994) Analytical Biochemistry , vol.221 , pp. 189-199
    • Karamanos, N.K.1    Syrokou, A.2    Vanky, P.3    Nurminen, M.4    Hjerpe, A.5
  • 31
    • 0029921062 scopus 로고    scopus 로고
    • High performance capillary electrophoresis method to characterize heparin and heparan sulfate disaccharides
    • Karamanos NK, Vanky P, Tzanakakis GN and Hjerpe A. High performance capillary electrophoresis method to characterize heparin and heparan sulfate disaccharides. Electrophoresis 1996; 17(2): 391-395.
    • (1996) Electrophoresis , vol.17 , Issue.2 , pp. 391-395
    • Karamanos, N.K.1    Vanky, P.2    Tzanakakis, G.N.3    Hjerpe, A.4
  • 32
    • 0030899830 scopus 로고    scopus 로고
    • Ion-pair high-performance liquid chromatography for determining disaccharide composition in heparin and heparin sulphate
    • Karamanos NK, Vanky P, Tzanakakis GN, Tsegenidis T and Hjerpe A. Ion-pair high-performance liquid chromatography for determining disaccharide composition in heparin and heparin sulphate. Journal of Chromatography A 1997; 765: 169-179.
    • (1997) Journal of Chromatography A , vol.765 , pp. 169-179
    • Karamanos, N.K.1    Vanky, P.2    Tzanakakis, G.N.3    Tsegenidis, T.4    Hjerpe, A.5
  • 33
    • 0031952152 scopus 로고    scopus 로고
    • Disaccharide analysis of heparin and heparan sulfate using deaminative cleavage with nitrous acid and subsequent labeling with paranitrophenyl hydrazine
    • Kariya Y, Hermann J, Suzuki K, Isomura T and Ishihara M. Disaccharide analysis of heparin and heparan sulfate using deaminative cleavage with nitrous acid and subsequent labeling with paranitrophenyl hydrazine. Journal of Biochemistry 1998; 123: 240-246.
    • (1998) Journal of Biochemistry , vol.123 , pp. 240-246
    • Kariya, Y.1    Hermann, J.2    Suzuki, K.3    Isomura, T.4    Ishihara, M.5
  • 35
    • 0035912848 scopus 로고    scopus 로고
    • Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1, 4-N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/heparin biosynthesis
    • Kim BT, Kitagawa H, Tamura J, Saito T, Kusche-Gullberg M, Lindahl U and Sugahara K. Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1, 4-N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/heparin biosynthesis. Proceedings of the National Academy of Science USA 2001; 98: 7176-7181.
    • (2001) Proceedings of the National Academy of Science USA , vol.98 , pp. 7176-7181
    • Kim, B.T.1    Kitagawa, H.2    Tamura, J.3    Saito, T.4    Kusche-Gullberg, M.5    Lindahl, U.6    Sugahara, K.7
  • 36
    • 0344848565 scopus 로고    scopus 로고
    • Microanalysis of glycosaminoglycan-derived oligosaccharides labeled with a fluorophore 2-aminobenzamide by high-performance liquid chromatography: application to disaccharide composition analysis and exosequencing of oligosaccharides
    • Kinoshita A and Sugahara K. Microanalysis of glycosaminoglycan-derived oligosaccharides labeled with a fluorophore 2-aminobenzamide by high-performance liquid chromatography: application to disaccharide composition analysis and exosequencing of oligosaccharides. Analytical Biochemistry 1999; 269: 367-378.
    • (1999) Analytical Biochemistry , vol.269 , pp. 367-378
    • Kinoshita, A.1    Sugahara, K.2
  • 37
    • 0028858338 scopus 로고
    • Microanalysis of glycosaminoglycan-derived disaccharides labeled with a fluorophore 2-aminoacridone by capillary electrophoresis and high-performance liquid chromatography
    • Kitagawa H, Kinoshita A and Sugahara K. Microanalysis of glycosaminoglycan-derived disaccharides labeled with a fluorophore 2-aminoacridone by capillary electrophoresis and high-performance liquid chromatography. Analytical Biochemistry 1995; 232: 114-121.
    • (1995) Analytical Biochemistry , vol.232 , pp. 114-121
    • Kitagawa, H.1    Kinoshita, A.2    Sugahara, K.3
  • 38
    • 0033553525 scopus 로고    scopus 로고
    • The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylglucosamine to the common glycosaminoglycan-protein linkage region
    • Kitagawa H, Shimakawa H and Sugahara K. The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The Journal of Biological Chemistry 1999; 274: 13933-13937.
    • (1999) The Journal of Biological Chemistry , vol.274 , pp. 13933-13937
    • Kitagawa, H.1    Shimakawa, H.2    Sugahara, K.3
  • 40
    • 0037167009 scopus 로고    scopus 로고
    • Analysis of heparan sulfate oligosaccharides with ion pair-reverse phase capillary high performance liquid chromatography-microelectrospray ionization time-of-flight mass spectrometry
    • Kuberan B, Lech M, Zhang L, Wu Z.L, Beeler DL and Rosenberg RD. Analysis of heparan sulfate oligosaccharides with ion pair-reverse phase capillary high performance liquid chromatography-microelectrospray ionization time-of-flight mass spectrometry. Journal of the American Chemical Society 2002, 124: 8707-8718.
    • (2002) Journal of the American Chemical Society , vol.124 , pp. 8707-8718
    • Kuberan, B.1    Lech, M.2    Zhang, L.3    Wu, Z.L.4    Beeler, D.L.5    Rosenberg, R.D.6
  • 41
    • 0034828630 scopus 로고    scopus 로고
    • Capillary electrophoresis: a superior miniaturized tool for analysis of the mono-, di-, and oligosaccharide constituents of glycan moieties in proteoglycans
    • Lamari FN, Militsopoulou M, Gioldassi X and Karamanos NK. Capillary electrophoresis: a superior miniaturized tool for analysis of the mono-, di-, and oligosaccharide constituents of glycan moieties in proteoglycans. Fresenius' Journal of Analytical Chemistry 2001; 371: 157-167.
    • (2001) Fresenius' Journal of Analytical Chemistry , vol.371 , pp. 157-167
    • Lamari, F.N.1    Militsopoulou, M.2    Gioldassi, X.3    Karamanos, N.K.4
  • 42
    • 0036198022 scopus 로고    scopus 로고
    • Analysis of glycosaminoglycan-derived disaccharides in biologic samples by capillary electrophoresis and protocol for sequencing glycosaminoglycans
    • Lamari FN, Militsopoulou M, Mitropoulou TN, Hjerpe A and Karamanos NK. Analysis of glycosaminoglycan-derived disaccharides in biologic samples by capillary electrophoresis and protocol for sequencing glycosaminoglycans. Biomedical Chromatography 2002; 16: 95-102.
    • (2002) Biomedical Chromatography , vol.16 , pp. 95-102
    • Lamari, F.N.1    Militsopoulou, M.2    Mitropoulou, T.N.3    Hjerpe, A.4    Karamanos, N.K.5
  • 43
    • 0036463453 scopus 로고    scopus 로고
    • Novel drug development opportunities for heparin
    • Lever R and Page CP. Novel drug development opportunities for heparin. Nature Reviews Drug Discovery 2002; 1: 140-148.
    • (2002) Nature Reviews Drug Discovery , vol.1 , pp. 140-148
    • Lever, R.1    Page, C.P.2
  • 44
    • 70449604674 scopus 로고    scopus 로고
    • Heparin, heparan sulfate and heparanase in inflammatory reactions
    • Li JP and Vlodavsky I. Heparin, heparan sulfate and heparanase in inflammatory reactions. Thrombosis and Haemostasis 2009; 102: 823-828.
    • (2009) Thrombosis and Haemostasis , vol.102 , pp. 823-828
    • Li, J.P.1    Vlodavsky, I.2
  • 46
    • 0033380689 scopus 로고    scopus 로고
    • What else can 'heparin' do?
    • Lindahl U. What else can 'heparin' do? Haemostasis 1999; 29(suppl. S1): 38-47.
    • (1999) Haemostasis , vol.29 , Issue.SUPPL. S1 , pp. 38-47
    • Lindahl, U.1
  • 48
    • 0024409990 scopus 로고
    • Sequence analysis of highly sulfated heparin-derived oligosaccharides using fast atom bombardment mass spectrometry
    • Mallis LM, Wang HM, Loganathan D and Linhardt RJ. Sequence analysis of highly sulfated heparin-derived oligosaccharides using fast atom bombardment mass spectrometry. Analytical Chemistry 1989; 61: 1453-1458.
    • (1989) Analytical Chemistry , vol.61 , pp. 1453-1458
    • Mallis, L.M.1    Wang, H.M.2    Loganathan, D.3    Linhardt, R.J.4
  • 49
    • 77956646126 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: the multiple roles of syndecan shedding
    • Manon-Jensen T, Itoh Y and Couchman JR. Proteoglycans in health and disease: the multiple roles of syndecan shedding. FEBS Journal 2010; 19: 3876-3889.
    • (2010) FEBS Journal , vol.19 , pp. 3876-3889
    • Manon-Jensen, T.1    Itoh, Y.2    Couchman, J.R.3
  • 50
    • 0033458043 scopus 로고    scopus 로고
    • A sulfated proteoglycan aggregation factor mediates amyloid-β peptide fibril formation and neurotoxicity
    • McLaurin J, Franklin T, Kuhns W and Fraser P. A sulfated proteoglycan aggregation factor mediates amyloid-β peptide fibril formation and neurotoxicity. Amyloid 1999; 6: 233-243.
    • (1999) Amyloid , vol.6 , pp. 233-243
    • McLaurin, J.1    Franklin, T.2    Kuhns, W.3    Fraser, P.4
  • 52
    • 0036099686 scopus 로고    scopus 로고
    • Determination of twelve heparin- and heparan sulfate-derived disaccharides as 2-aminoacridone derivatives by capillary zone electrophoresis using ultraviolet and laser-induced fluorescence detection
    • Militsopoulou M, Lamari F, Hjerpe A and Karamanos NK. Determination of twelve heparin- and heparan sulfate-derived disaccharides as 2-aminoacridone derivatives by capillary zone electrophoresis using ultraviolet and laser-induced fluorescence detection. Electrophoresis 2002; 23: 1104-1109.
    • (2002) Electrophoresis , vol.23 , pp. 1104-1109
    • Militsopoulou, M.1    Lamari, F.2    Hjerpe, A.3    Karamanos, N.K.4
  • 53
    • 0042625049 scopus 로고    scopus 로고
    • Capillary electrophoresis: a tool for studying interactions of glycans/proteoglycans with growth factors
    • Militsopoulou M, Lamari F and Karamanos NK. Capillary electrophoresis: a tool for studying interactions of glycans/proteoglycans with growth factors. Journal of Pharmaceutical and Biomedical Analysis 2003; 32: 823-828.
    • (2003) Journal of Pharmaceutical and Biomedical Analysis , vol.32 , pp. 823-828
    • Militsopoulou, M.1    Lamari, F.2    Karamanos, N.K.3
  • 54
    • 0028855668 scopus 로고
    • Preparation and structural characterization of large heparin-derived oligosaccharides
    • Pervin A, Gallo C, Jandik K, Han X and Linhardt R. Preparation and structural characterization of large heparin-derived oligosaccharides. Glycobiology 1995; 5: 83-95.
    • (1995) Glycobiology , vol.5 , pp. 83-95
    • Pervin, A.1    Gallo, C.2    Jandik, K.3    Han, X.4    Linhardt, R.5
  • 55
    • 0030446668 scopus 로고    scopus 로고
    • Ion exchange HPLC microanalysis of chondroitin sulfate: quantitative derivatization of chondroitin lyase digestion products with 2-aminopyridine
    • Plaas AH, Hascall VC and Midura RJ. Ion exchange HPLC microanalysis of chondroitin sulfate: quantitative derivatization of chondroitin lyase digestion products with 2-aminopyridine. Glycobiology 1996; 6: 823-829.
    • (1996) Glycobiology , vol.6 , pp. 823-829
    • Plaas, A.H.1    Hascall, V.C.2    Midura, R.J.3
  • 56
    • 2442549670 scopus 로고    scopus 로고
    • Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches
    • Powell AK, Yates E A, Fernig DG and Turnbull JE. Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches. Glycobiology 2004; 12: 17R-30R.
    • (2004) Glycobiology , vol.12
    • Powell, A.K.1    Yates, E.A.2    Fernig, D.G.3    Turnbull, J.E.4
  • 58
    • 77950559481 scopus 로고    scopus 로고
    • Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis
    • Purushothaman A, Uyama T, Kobayashi F, Yamada S, Sugahara K, Rapraeger AC and Sanderson RD. Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis. Blood 2010; 115: 2449-2457.
    • (2010) Blood , vol.115 , pp. 2449-2457
    • Purushothaman, A.1    Uyama, T.2    Kobayashi, F.3    Yamada, S.4    Sugahara, K.5    Rapraeger, A.C.6    Sanderson, R.D.7
  • 59
    • 0032483520 scopus 로고    scopus 로고
    • Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity
    • Pye DA, Vives RR, Turnbull JE, Hyde P and Gallagher JT. Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity. The Journal of Biological Chemistry 1998; 273: 22936-22942.
    • (1998) The Journal of Biological Chemistry , vol.273 , pp. 22936-22942
    • Pye, D.A.1    Vives, R.R.2    Turnbull, J.E.3    Hyde, P.4    Gallagher, J.T.5
  • 60
    • 0032516018 scopus 로고    scopus 로고
    • Mass spectrometric and capillary electrophoretic investigation of the enzymatic degradation of heparin-like glycosaminoglycans
    • Rhomberg AJ, Ernst S, Sasisekharan R and Biemann K. Mass spectrometric and capillary electrophoretic investigation of the enzymatic degradation of heparin-like glycosaminoglycans. Proceedings of the National Academy of Science USA 1998; 95: 4176-4181.
    • (1998) Proceedings of the National Academy of Science USA , vol.95 , pp. 4176-4181
    • Rhomberg, A.J.1    Ernst, S.2    Sasisekharan, R.3    Biemann, K.4
  • 61
    • 0023654989 scopus 로고
    • Fractionation of heparin-derived oligosaccharides by gradient polyacrylamide-gel electrophoresis
    • Rice KG, Rottink MK and Linhardt RJ. Fractionation of heparin-derived oligosaccharides by gradient polyacrylamide-gel electrophoresis. Biochemical Journal 1987; 244: 515-522.
    • (1987) Biochemical Journal , vol.244 , pp. 515-522
    • Rice, K.G.1    Rottink, M.K.2    Linhardt, R.J.3
  • 62
    • 0035918014 scopus 로고    scopus 로고
    • Pressure-assisted capillary electrophoresis-electrospray ion trap mass spectrometry for the analysis of heparin depolymerised disaccharides
    • Ruiz-Calero V, Moyano E, Puignou L and Galceran MT. Pressure-assisted capillary electrophoresis-electrospray ion trap mass spectrometry for the analysis of heparin depolymerised disaccharides. Journal of Chromatography A 2001; 914: 277-291.
    • (2001) Journal of Chromatography A , vol.914 , pp. 277-291
    • Ruiz-Calero, V.1    Moyano, E.2    Puignou, L.3    Galceran, M.T.4
  • 63
  • 64
    • 66149147074 scopus 로고    scopus 로고
    • Labelling heparan sulphate saccharides with chromophore, fluorescence and mass tags for HPLC and MS separations
    • Skidmore M, Atrih A, Yates E and Turnbull JE. Labelling heparan sulphate saccharides with chromophore, fluorescence and mass tags for HPLC and MS separations. Methods in Molecular Biology (Clifton, NJ) 2009; 534: 157-169.
    • (2009) Methods in Molecular Biology (Clifton, NJ) , vol.534 , pp. 157-169
    • Skidmore, M.1    Atrih, A.2    Yates, E.3    Turnbull, J.E.4
  • 67
    • 1642453684 scopus 로고    scopus 로고
    • Liquid chromatography/mass spectrometry sequencing approach for highly sulphated heparin-derived oligosaccharides
    • Thanawiroon C, Rice KG, Toida T, Linhardt RJ. Liquid chromatography/mass spectrometry sequencing approach for highly sulphated heparin-derived oligosaccharides. The Journal of Biological Chemistry 2004, 279: 2608-2615.
    • (2004) The Journal of Biological Chemistry , vol.279 , pp. 2608-2615
    • Thanawiroon, C.1    Rice, K.G.2    Toida, T.3    Linhardt, R.J.4
  • 68
    • 77956641177 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting
    • Theocharis AD, Skandalis SS, Tzanakakis GN and Karamanos NK. Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting. FEBS Journal 2010; 19: 3904-3923.
    • (2010) FEBS Journal , vol.19 , pp. 3904-3923
    • Theocharis, A.D.1    Skandalis, S.S.2    Tzanakakis, G.N.3    Karamanos, N.K.4
  • 69
    • 0031578905 scopus 로고    scopus 로고
    • Sensitive high-performance liquid chromatographic method with fluorometric detection for the determination of heparin and heparan sulfate in biological samples: application to human urinary heparan sulfate
    • Toyoda H, Nagashima T, Hirata R, Toida T and Imanari T. Sensitive high-performance liquid chromatographic method with fluorometric detection for the determination of heparin and heparan sulfate in biological samples: application to human urinary heparan sulfate. Journal of Chromatography B 1997; 704: 19-24.
    • (1997) Journal of Chromatography B , vol.704 , pp. 19-24
    • Toyoda, H.1    Nagashima, T.2    Hirata, R.3    Toida, T.4    Imanari, T.5
  • 76
    • 0037027866 scopus 로고    scopus 로고
    • Advances in analysis of glycosaminoglycans: its application for the assessment of physiological and pathological states of connective tissues
    • Vynios DH, Karamanos NK and Tsiganos CP. Advances in analysis of glycosaminoglycans: its application for the assessment of physiological and pathological states of connective tissues. Journal of Chromatography B 2002; 781: 21-38.
    • (2002) Journal of Chromatography B , vol.781 , pp. 21-38
    • Vynios, D.H.1    Karamanos, N.K.2    Tsiganos, C.P.3
  • 77
    • 0028039867 scopus 로고
    • Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor
    • Walker A, Turnbull JE and Gallagher JT. Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor. The Journal of Biological Chemistry 1994; 269: 931-935.
    • (1994) The Journal of Biological Chemistry , vol.269 , pp. 931-935
    • Walker, A.1    Turnbull, J.E.2    Gallagher, J.T.3
  • 78
    • 0037610516 scopus 로고    scopus 로고
    • Heparin induced thrombocytopenia and cardiac surgery
    • Warkentin TE and Greinacher A. Heparin induced thrombocytopenia and cardiac surgery. Annals of Thoracic Surgery 2003; 76: 638-648.
    • (2003) Annals of Thoracic Surgery , vol.76 , pp. 638-648
    • Warkentin, T.E.1    Greinacher, A.2
  • 79
    • 0027513987 scopus 로고
    • Structural studies on the bacteria lyase-resistant tetrasaccharides derived from the antithrombin binding site of porcine mucosal intestinal heparin
    • Yamada S, Yoshida K, Sugiura M, Sugahara K, Khoo K, Morris H and Dell A. Structural studies on the bacteria lyase-resistant tetrasaccharides derived from the antithrombin binding site of porcine mucosal intestinal heparin. The Journal of Biological Chemistry 1993; 268: 4780-4787.
    • (1993) The Journal of Biological Chemistry , vol.268 , pp. 4780-4787
    • Yamada, S.1    Yoshida, K.2    Sugiura, M.3    Sugahara, K.4    Khoo, K.5    Morris, H.6    Dell, A.7
  • 80
    • 0031892170 scopus 로고    scopus 로고
    • A major common trisulfated hexasaccharide core sequence, hexuronic acid(2-sulfate)-glucosamine(N-sulfate)-iduronic acid-N-acetylglucosamine-glucuronic acid-glucosamine(N-sulfate), isolated from the low sulfated irregular region of porcine intestinal heparin
    • Yamada S, Yamane Y, Tsuda H, Yoshida K and Sugahara K. A major common trisulfated hexasaccharide core sequence, hexuronic acid(2-sulfate)-glucosamine(N-sulfate)-iduronic acid-N-acetylglucosamine-glucuronic acid-glucosamine(N-sulfate), isolated from the low sulfated irregular region of porcine intestinal heparin. The Journal of Biological Chemistry 1998; 273: 1863-1871.
    • (1998) The Journal of Biological Chemistry , vol.273 , pp. 1863-1871
    • Yamada, S.1    Yamane, Y.2    Tsuda, H.3    Yoshida, K.4    Sugahara, K.5
  • 81
    • 32944479184 scopus 로고    scopus 로고
    • Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation
    • Zetser A, Bashenko Y, Edovitsky E, Levy- Adam F, Vlodavsky I and Ilan N. Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation. Cancer Research 2006; 66: 1455-1463.
    • (2006) Cancer Research , vol.66 , pp. 1455-1463
    • Zetser, A.1    Bashenko, Y.2    Edovitsky, E.3    Levy- Adam, F.4    Vlodavsky, I.5    Ilan, N.6


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