A redundant function for the N-terminal tail of Ndc80 in kinetochore-microtubule interaction in Saccharomyces cerevisiae

Genetics

Volumn 192, Issue 2, 2012, Pages 753-756

  Demirel, Pinar B ^a   Keyes, Brice E ^a   Chaterjee, Mandovi ^b   Remington, Courtney E ^a   Burke, Daniel J ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; NDC80 COMPLEX; PROTEIN DAM1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL VIABILITY; CENTROMERE; CHROMOSOME SEGREGATION; MICROTUBULE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE; YEAST;

CELL CYCLE PROTEINS; CHROMOSOME SEGREGATION; KINETOCHORES; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOSIS; NUCLEAR PROTEINS; PHENOTYPE; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 84867177727     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.112.143818     Document Type: Article

References (21)

1. Alushin, G. M., V. H. Ramey, S. Pasqualato, D. A. Ball, N. Grigorieff et al., 2010 The Ndc80 kinetochore complex forms oligomeric arrays along microtubules. Nature 467: 805-810.
2. Ciferri, C., S. Pasqualato, E. Screpanti, G. Varetti, S. Santaguida et al., 2008 Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex. Cell 133: 427-439.
3. Guimaraes, G. J., Y. Dong, B. F. McEwen, and J. G. Deluca, 2008 Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1. Curr. Biol. 18: 1778-1784.
4. Kemmler, S., M. Stach, M. Knapp, J. Ortiz, J. Pfannstiel et al., 2009 Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signalling. EMBO J. 28: 1099-1110.
5. Keyes, B. E., and D. J. Burke, 2009 Irc15 is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiae. Curr. Biol. 19: 472-478.
6. Lampert, F., P. Hornung, and S. Westermann, 2010 The Dam1 complex confers microtubule plus end-tracking activity to the Ndc80 kinetochore complex. J. Cell Biol. 189: 641-649.
7. Lampson, M. A., and I. M. Cheeseman, 2011 Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol. 21: 133-140.
8. Li, Y., J. Bachant, A. A. Alcasabas, Y. Wang, J. Qin et al., 2002 The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev. 16: 183-197.
9. McCleland, M. L., R. D. Gardner, M. J. Kallio, J. R. Daum, G. J. Gorbsky et al., 2003 The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Genes Dev. 17: 101-114.
10. Miller, S. A., M. L. Johnson, and P. T. Stukenberg, 2008 Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1). Curr. Biol. 18: 1785-1791.
11. Miranda, J. J., P. De Wulf, P. K. Sorger, and S. C. Harrison, 2005 The yeast DASH complex forms closed rings on microtubules. Nat. Struct. Mol. Biol. 12: 138-143.
12. Strathern, J., J. Hicks, and I. Herskowitz, 1981 Control of cell type in yeast by the mating type locus. The alpha 1-alpha 2 hypothesis. J. Mol. Biol. 147: 357-372.
13. Tien, J. F., N. T. Umbreit, D. R. Gestaut, A. D. Franck, J. Cooper et al., 2010 Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B. J. Cell Biol. 189: 713-723.
14. Tooley, J., and P. T. Stukenberg, 2011 The Ndc80 complex: integrating the kinetochore's many movements. Chromosome Res. 19: 377-391.
15. Tooley, J. G., S. A. Miller, and P. T. Stukenberg, 2011 The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement. Mol. Biol. Cell 22: 1217-1226.
16. Warren, C. D., D. M. Eckley, M. S. Lee, J. S. Hanna, A. Hughes et al., 2004 S-phase checkpoint genes safeguard high-fidelity sister chromatid cohesion. Mol. Biol. Cell 15: 1724-1735.
17. Wei, R. R., P. K. Sorger, and S. C. Harrison, 2005 Molecular organization of the Ndc80 complex, an essential kinetochore component. Proc. Natl. Acad. Sci. USA 102: 5363-5367.
18. Welburn, J. P., M. Vleugel, D. Liu, J. R. Yates III., M. A. Lampson et al., 2010 Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface. Mol. Cell 38: 383-392.
19. Westermann, S., H. W. Wang, A. Avila-Sakar, D. G. Drubin, E. Nogales et al., 2006 The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440: 565-569.
20. Wigge, P. A., and J. V. Kilmartin, 2001 The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. J. Cell Biol. 152: 349-360.
21. Yellman, C. M., and D. J. Burke, 2006 The role of Cdc55 in the spindle checkpoint is through regulation of mitotic exit in Saccharomyces cerevisiae. Mol. Biol. Cell 17: 658-666.