The calcium-dependent regulation of spheroid formation and cardiomyogenic differentiation for MSCs on chitosan membranes

Biomaterials

Volumn 33, Issue 35, 2012, Pages 8943-8954

  Yeh, Hsi Yi ^a   Liu, Bing Hsien ^a   Hsu, Shan Hui ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Adipose derived adult stem cells (ADAS); Cardiomyogenesis; Chitosan; Intracellular calcium; Spheroids

Indexed keywords

ACETYLATED CHITOSAN; ADULT STEM CELLS; CALCIUM BINDING; CALCIUM CONCENTRATION; CARDIAC MARKERS; CARDIOMYOGENESIS; CELL SUBSTRATES; CELL-CELL INTERACTION; CHITOSAN MEMBRANE; CULTURE MEDIUM; CULTURE SUBSTRATE; EXPRESSION LEVELS; IMMUNOFLUORESCENCE STAINING; INTRACELLULAR CALCIUM; INTRACELLULAR CALCIUM LEVELS; MEMBRANE THICKNESS; MESENCHYMAL STEM CELL; MULTICELLULAR SPHEROID; PHYSICOCHEMICAL CHARACTERISTICS; QUANTITATIVE RT-PCR; SPHEROIDS; TIGHT JUNCTIONS; TISSUE CULTURE POLYSTYRENES; WESTERN BLOTS;

ACETYLATION; CALCIUM; CYTOLOGY; FLOWCHARTING; GENE EXPRESSION; MEMBRANES; POLYSTYRENES; POLYVINYL ALCOHOLS; STEM CELLS; TISSUE CULTURE;

CHITOSAN;

CALCIUM; CHITOSAN; NERVE CELL ADHESION MOLECULE; POLYSTYRENE; POLYVINYL ALCOHOL; PROTEIN ZO1; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5; WNT11 PROTEIN;

ACETYLATION; ADIPOSE TISSUE; ADULT STEM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM BINDING; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL INTERACTION; CELL MEMBRANE; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; HEART MUSCLE CELL; IMMUNOFLUORESCENCE; MESENCHYMAL STEM CELL; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPHEROID CELL; TISSUE CULTURE; UPREGULATION; WESTERN BLOTTING;

ACETYLATION; ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; CADHERINS; CALCIUM; CALMODULIN; CELL DIFFERENTIATION; CELLS, CULTURED; CHITOSAN; MESENCHYMAL STROMAL CELLS; NERVE TISSUE PROTEINS; RATS; SPHEROIDS, CELLULAR; UP-REGULATION; WNT PROTEINS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84867140065     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.08.069     Document Type: Article

References (38)

1. Watt F.M., Hogan B.L. Out of Eden: stem cells and their niches. Science 2000, 287:1427-1430.
2. Gerecht-Nir S., Cohen S., Itskovitz-Eldor J. Bioreactor cultivation enhances the efficiency of human embryoid body (hEB) formation and differentiation. Biotechnol Bioeng 2004, 86:493-502.
3. Yeh H.Y., Lin J.C. Surface phosphorylation for polyelectrolyte complex of chitosan and its sulfonated derivative: surface analysis, blood compatibility and adipose derived stem cell contact properties. J Biomater Sci Polym Ed 2012, 23:233-250.
4. Amaral I.F., Unger R.E., Fuchs S., Mendonca A.M., Sousa S.R., Barbosa M.A., et al. Fibronectin-mediated endothelialisation of chitosan porous matrices. Biomaterials 2009, 30:5465-5475.
5. Wang A.H., Chen X.G., Liu C.S., Meng X.H., Yu L.J., Wang H. Preparation and characteristics of chitosan microspheres in different acetylation as drug carrier system. J Microencapsul 2009, 26:593-602.
6. Barbosa J.N., Amaral I.F., Aguas A.P., Barbosa M.A. Evaluation of the effect of the degree of acetylation on the inflammatory response to 3D porous chitosan scaffolds. J Biomed Mater Res A 2010, 93:20-28.
7. Moutzouri A.G., Athanassiou G.M. Attachment, spreading, and adhesion strength of human bone marrow cells on chitosan. Ann Biomed Eng 2011, 39:730-741.
8. Zuk P.A., Zhu M., Ashjian P., De Ugarte D.A., Huang J.I., Mizuno H., et al. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002, 13:4279-4295.
9. Malafaya P.B., Pedro A.J., Peterbauer A., Gabriel C., Redl H., Reis R.L. Cartilage and osteochondral tissue engineering approaches with adipose tissue derived stem cells. J Mater Sci Mater Med 2005, 16:1077-1085.
10. Seo M.J., Suh S.Y., Bae Y.C., Jung J.S. Differentiation of human adipose stromal cells into hepatic lineage in vitro and in vivo. Biochem Biophys Res Commun 2005, 328:258-264.
11. Bai X., Alt E. Myocardial regeneration potential of adipose tissue-derived stem cells. Biochem Biophys Res Commun 2010, 401:321-326.
12. Safford K.M., Safford S.D., Gimble J.M., Shetty A.K., Rice H.E. Characterization of neuronal/glial differentiation of murine adipose-derived adult stromal cells. Exp Neurol 2004, 187:319-328.
13. Huang G.S., Dai L.G., Yen B.L., Hsu S.H. Spheroid formation of mesenchymal stem cells on chitosan and chitosan-hyaluronan membranes. Biomaterials 2011, 32:6929-6945.
14. Mathews S., Gupta P.K., Bhonde R., Totey S. Chitosan enhances mineralization during osteoblast differentiation of human bone marrow-derived mesenchymal stem cells, by upregulating the associated genes. Cell Prolif 2011, 44:537-549.
15. Cheng N.C., Wang S., Young T.H. The influence of spheroid formation of human adipose-derived stem cells on chitosan films on stemness and differentiation capabilities. Biomaterials 2012, 33:1748-1758.
16. Bartosh T.J., Ylostalo J.H., Mohammadipoor A., Bazhanov N., Coble K., Claypool K., et al. Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties. Proc Natl Acad Sci U S A 2010, 107:13724-13729.
17. Frith J.E., Thomson B., Genever P.G. Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential. Tissue Eng Part C Methods 2010, 16:735-749.
18. Wang W., Itaka K., Ohba S., Nishiyama N., Chung U.I., Yamasaki Y., et al. 3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells. Biomaterials 2009, 30:2705-2715.
19. Wang C.C., Chen C.H., Hwang S.M., Lin W.W., Huang C.H., Lee W.Y., et al. Spherically symmetric mesenchymal stromal cell bodies inherent with endogenous extracellular matrices for cellular cardiomyoplasty. Stem Cells 2009, 27:724-732.
20. Lee W.Y., Chang Y.H., Yeh Y.C., Chen C.H., Lin K.M., Huang C.C., et al. The use of injectable spherically symmetric cell aggregates self-assembled in a thermo-responsive hydrogel for enhanced cell transplantation. Biomaterials 2009, 30:5505-5513.
21. Hsu S.H., Huang G.S., Feng F. Isolation of the multipotent MSC subpopulation from human gingival fibroblasts by culturing on chitosan membranes. Biomaterials 2012, 33:2642-2655.
22. Sakai Y., Nakazawa K. Technique for the control of spheroid diameter using microfabricated chips. Acta Biomater 2007, 3:1033-1040.
23. Otsuka H., Hirano A., Nagasaki Y., Okano T., Horiike Y., Kataoka K. Two-dimensional multiarray formation of hepatocyte spheroids on a microfabricated PEG-brush surface. Chembiochem 2004, 5:850-855.
24. Hsu S.H., Huang G.S., Lin S.Y., Feng F., Ho T.T., Liao Y.C. Enhanced chondrogenic differentiation potential of human gingival fibroblasts by spheroid formation on chitosan membranes. Tissue Eng Part A 2012, 18:67-79.
25. Hsu S.H., Ho T.T., Tseng T.C. Nanoparticle uptake and gene transfer efficiency for MSCs on chitosan and chitosan-hyaluronan substrates. Biomaterials 2012, 33:3639-3650.
26. Li B., Wang Y., Jia D., Zhou Y. Gradient structural bone-like apatite induced by chitosan hydrogel via ion assembly. J Biomater Sci Polym Ed 2011, 22:505-517.
27. Kubota N., Tatsumoto N., Sano T., Toya K. A simple preparation of half N-acetylated chitosan highly soluble in water and aqueous organic solvents. Carbohydr Res 2000, 324:268-274.
28. Vandewalle B., Revillion F., Doutrelant P., Granier A., Lefebvre J. Effect of calcium on e-cadherin expression in breast-tumor cells. Int J Oncol 1994, 4:181-185.
29. Alexander N.R., Tran N.L., Rekapally H., Summers C.E., Glackin C., Heimark R.L. N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1. Cancer Res 2006, 66:3365-3369.
30. Leckband D.E., le Duc Q., Wang N., de Rooij J. Mechanotransduction at cadherin-mediated adhesions. Curr Opin Cell Biol 2011, 23:523-530.
31. Becker S.F., Langhe R., Huang C., Wedlich D., Kashef J. Giving the right tug for migration: cadherins in tissue movements. Arch Biochem Biophys 2012, 524:30-42.
32. Modarresi R., Lafond T., Roman-Blas J.A., Danielson K.G., Tuan R.S., Seghatoleslami M.R. N-cadherin mediated distribution of beta-catenin alters MAP kinase and BMP-2 signaling on chondrogenesis-related gene expression. J Cell Biochem 2005, 95:53-63.
33. Shoval I., Ludwig A., Kalcheim C. Antagonistic roles of full-length N-cadherin and its soluble BMP cleavage product in neural crest delamination. Development 2007, 134:491-501.
34. Arnsdorf E.J., Tummala P., Jacobs C.R. Non-canonical wnt signaling and N-cadherin related beta-catenin signaling play a role in mechanically induced osteogenic cell fate. PLoS ONE 2009, 4:e5388.
35. Gessert S., Kuhl M. The multiple phases and faces of wnt signaling during cardiac differentiation and development. Circ Res 2010, 107:186-199.
36. Puceat M., Jaconi M. Ca2+ signalling in cardiogenesis. Cell Calcium 2005, 38:383-389.
37. Uysal-Onganer P., Kypta R.M. Wnt11 in 2011-the regulation and function of a non-canonical wnt. Acta Physiol (Oxf) 2012, 204:52-64.
38. Kim M.H., Kino-oka M., Maruyama N., Saito A., Sawa Y., Taya M. Cardiomyogenic induction of human mesenchymal stem cells by altered Rho family GTPase expression on dendrimer-immobilized surface with D-glucose display. Biomaterials 2010, 31:7666-7677.