The use of pH-sensitive positively charged polymeric micelles for protein delivery

Biomaterials

Volumn 33, Issue 35, 2012, Pages 9157-9164

  Gao, Guang Hui ^a,e   Park, Min Jung ^b   Li, Yi ^a   Im, Geun Ho ^c   Kim, Jae Hoon ^b   Kim, Hun Nyun ^c   Lee, Jae Won ^c   Jeon, Pyoung ^b   Bang, Oh Young ^b   Lee, Jung Hee ^b,c,d   Lee, Doo Sung ^a  

^a Sungkyunkwan University   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Samsung Medical Center   (South Korea)

^d Samsung Advanced Institute of Technology (SAIT)   (South Korea)

^e CHANGCHUN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Acidic cerebral ischemia; Human serum albumin; PH tunable positive charge; Polymeric micelle

Indexed keywords

ACIDIC ENVIRONMENT; AMINO ESTERS; CANCEROUS TISSUES; CELL LINES; CEREBRAL ISCHEMIA; DEGRADABLE BLOCK COPOLYMER; DIAGNOSTIC IMAGING; FLUORESCENCE SIGNALS; HUMAN SERUM ALBUMINS; IN-VITRO; IN-VIVO; METHOXYPOLYETHYLENE GLYCOL; MODEL PROTEINS; NANO-SIZED; PATHOLOGIC CONDITIONS; PH SENSITIVE; PH-DEPENDENT; POLYMER CONCENTRATIONS; POLYMERIC MICELLE; POSITIVE CHARGES; POSITIVELY CHARGED; PROTEIN DELIVERY; RAT MODEL; SCATTERING INTENSITY; SECONDARY STRUCTURES; SELF-ASSEMBLING; ZETA POTENTIAL MEASUREMENTS;

BLOCK COPOLYMERS; CELL CULTURE; CYTOTOXICITY; DIAGNOSIS; MICELLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; PROTEINS; TISSUE; TUNING; ZETA POTENTIAL;

POLYMERS;

COPOLYMER; HUMAN SERUM ALBUMIN; IMIDAZOLE; METHOXY POLY(ETHYLENE GLYCOL) POLY(BETA AMINO ESTER); PIPERIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CANCER TISSUE; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; DIAGNOSTIC IMAGING; ENCAPSULATION; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGHT SCATTERING; MALE; MICELLE; MICELLIZATION; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN SECONDARY STRUCTURE; PROTEIN TRANSPORT; RAT; ZETA POTENTIAL;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CIRCULAR DICHROISM; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; IMMOBILIZATION; INFARCTION, MIDDLE CEREBRAL ARTERY; MAGNETIC RESONANCE IMAGING; MALE; MICELLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMERS; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SERUM ALBUMIN;

RATTUS;

EID: 84867139131     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.09.016     Document Type: Article

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