메뉴 건너뛰기




Volumn 77, Issue 13, 2012, Pages 1345-1351

The rs4844880 polymorphism in the promoter region of the HSD11B1 gene associates with bone mineral density in healthy and postmenopausal osteoporotic women

Author keywords

11 hydroxysteroid dehydrogenase type 1; Bone mineral density; Osteoporosis

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; CARBOXY TERMINAL TELOPEPTIDE; LUCIFERASE; OSTEOCALCIN;

EID: 84867136856     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.08.014     Document Type: Article
Times cited : (21)

References (39)
  • 1
    • 20444436794 scopus 로고    scopus 로고
    • Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: The Hertfordshire Cohort Study
    • DOI 10.1111/j.1365-2265.2005.02281.x
    • M.S. Cooper, H.E. Syddall, C.H. Fall, P.J. Wood, P.M. Stewart, C. Cooper, and E.M. Dennison Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: the Hertfordshire Cohort Study Clin Endocrinol (Oxf) 62 2005 692 697 (Pubitemid 40825939)
    • (2005) Clinical Endocrinology , vol.62 , Issue.6 , pp. 692-697
    • Cooper, M.S.1    Syddall, H.E.2    Fall, C.H.D.3    Wood, P.J.4    Stewart, P.M.5    Cooper, C.6    Dennison, E.M.7
  • 2
    • 34250791225 scopus 로고    scopus 로고
    • Readjusting the glucocorticoid balance: An opportunity for modulators of 11β-hydroxysteroid dehydrogenase type 1 activity?
    • A.G. Atanasov, and A. Odermatt Readjusting the glucocorticoid balance. an opportunity for modulators of 11beta-hydroxysteroid dehydrogenase type 1 activity? Endocr Metab Immune Disord Drug Targets 7 2007 125 140 (Pubitemid 46965221)
    • (2007) Endocrine, Metabolic and Immune Disorders - Drug Targets , vol.7 , Issue.2 , pp. 125-140
    • Atanasov, A.G.1    Odermatt, A.2
  • 4
    • 23844516967 scopus 로고    scopus 로고
    • 11β-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action
    • DOI 10.1677/joe.1.06019
    • N. Draper, and P.M. Stewart 11beta-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action J Endocrinol 186 2005 251 271 (Pubitemid 41167396)
    • (2005) Journal of Endocrinology , vol.186 , Issue.2 , pp. 251-271
    • Draper, N.1    Stewart, P.M.2
  • 5
    • 0033842430 scopus 로고    scopus 로고
    • Expression and functional consequences of 11β-hydroxysteroid dehydrogenase activity in human bone
    • DOI 10.1016/S8756-3282(00)00344-6, PII S8756328200003446
    • M.S. Cooper, E.A. Walker, R. Bland, W.D. Fraser, M. Hewison, and P.M. Stewart Expression and functional consequences of 11beta-hydroxysteroid dehydrogenase activity in human bone Bone 27 2000 375 381 (Pubitemid 30658120)
    • (2000) Bone , vol.27 , Issue.3 , pp. 375-381
    • Cooper, M.S.1    Walker, E.A.2    Bland, R.3    Fraser, W.D.4    Hewison, M.5    Stewart, P.M.6
  • 6
    • 0026095840 scopus 로고
    • The human gene for 11β-hydroxysteroid dehydrogenase: Structure, tissue distribution, and chromosomal localization
    • G.M. Tannin, A.K. Agarwal, C. Monder, M.I. New, and P.C. White The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization J Biol Chem 266 1991 16653 16658 (Pubitemid 21907849)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.25 , pp. 16653-16658
    • Tannin, G.M.1    Agarwal, A.K.2    Monder, C.3    New, M.I.4    White, P.C.5
  • 8
  • 9
    • 0042165967 scopus 로고    scopus 로고
    • Associations between a polymorphism in the 11 beta hydroxysteroid dehydrogenase type 1 gene and body composition
    • DOI 10.1038/sj.ijo.0802327
    • L. Gelernter-Yaniv, N. Feng, N.G. Sebring, Z. Hochberg, and J.A. Yanovski Associations between a polymorphism in the 11 beta hydroxysteroid dehydrogenase type I gene and body composition Int J Obes Relat Metab Disord 27 2003 983 986 (Pubitemid 36918622)
    • (2003) International Journal of Obesity , vol.27 , Issue.8 , pp. 983-986
    • Gelernter-Yaniv, L.1    Feng, N.2    Sebring, N.G.3    Hochberg, Z.4    Yanovski, J.A.5
  • 10
    • 3142661851 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase Type 1: Genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle
    • S. Nair, Y.H. Lee, R.S. Lindsay, B.R. Walker, P.A. Tataranni, C. Bogardus, L.J. Baier, and P.A. Permana 11beta-hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle Diabetologia 47 2004 1088 1095 (Pubitemid 38918169)
    • (2004) Diabetologia , vol.47 , Issue.6 , pp. 1088-1095
    • Nair, S.1    Lee, Y.H.2    Lindsay, R.S.3    Walker, B.R.4    Tataranni, P.A.5    Bogardus, C.6    Baier, L.J.7    Permana, P.A.8
  • 13
    • 70350230403 scopus 로고    scopus 로고
    • HSD11B1 polymorphisms predicted bone mineral density and fracture risk in postmenopausal women without a clinically apparent hypercortisolemia
    • J.Y. Hwang, S.H. Lee, G.S. Kim, J.M. Koh, M.J. Go, Y.J. Kim, H.C. Kim, T.H. Kim, J.M. Hong, E.K. Park, J.Y. Lee, and S.Y. Kim HSD11B1 polymorphisms predicted bone mineral density and fracture risk in postmenopausal women without a clinically apparent hypercortisolemia Bone 45 2009 1098 1103
    • (2009) Bone , vol.45 , pp. 1098-1103
    • Hwang, J.Y.1    Lee, S.H.2    Kim, G.S.3    Koh, J.M.4    Go, M.J.5    Kim, Y.J.6    Kim, H.C.7    Kim, T.H.8    Hong, J.M.9    Park, E.K.10    Lee, J.Y.11    Kim, S.Y.12
  • 14
    • 78650562305 scopus 로고    scopus 로고
    • The 83,557insA variant of the gene coding 11beta-hydroxysteroid dehydrogenase type 1 enzyme associates with serum osteocalcin in patients with endogenous Cushing's syndrome
    • A. Szappanos, A. Patocs, P. Gergics, R. Bertalan, A. Kerti, B. Acs, K. Feldmann, K. Racz, and M. Toth The 83,557insA variant of the gene coding 11beta-hydroxysteroid dehydrogenase type 1 enzyme associates with serum osteocalcin in patients with endogenous Cushing's syndrome J Steroid Biochem Mol Biol 123 2011 79 84
    • (2011) J Steroid Biochem Mol Biol , vol.123 , pp. 79-84
    • Szappanos, A.1    Patocs, A.2    Gergics, P.3    Bertalan, R.4    Kerti, A.5    Acs, B.6    Feldmann, K.7    Racz, K.8    Toth, M.9
  • 17
    • 73649118537 scopus 로고    scopus 로고
    • Functional effects of polymorphisms in the human gene encoding 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1): A sequence variant at the translation start of 11 beta-HSD1 alters enzyme levels
    • E.L. Malavasi, V. Kelly, N. Nath, A. Gambineri, R.S. Dakin, U. Pagotto, R. Pasquali, B.R. Walker, and K.E. Chapman Functional effects of polymorphisms in the human gene encoding 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1): a sequence variant at the translation start of 11 beta-HSD1 alters enzyme levels Endocrinology 151 2010 195 202
    • (2010) Endocrinology , vol.151 , pp. 195-202
    • Malavasi, E.L.1    Kelly, V.2    Nath, N.3    Gambineri, A.4    Dakin, R.S.5    Pagotto, U.6    Pasquali, R.7    Walker, B.R.8    Chapman, K.E.9
  • 19
    • 0033304809 scopus 로고    scopus 로고
    • Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis
    • L.C. Hofbauer, F. Gori, B.L. Riggs, D.L. Lacey, C.R. Dunstan, T.C. Spelsberg, and S. Khosla Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis Endocrinology 140 1999 4382 4389 (Pubitemid 30666099)
    • (1999) Endocrinology , vol.140 , Issue.10 , pp. 4382-4389
    • Hofbauer, L.C.1    Gori, F.2    Riggs, B.L.3    Lacey, D.L.4    Dunstan, C.R.5    Spelsberg, T.C.6    Khosla, S.7
  • 20
    • 0017647834 scopus 로고
    • Intestinal calcium absorption in exogenous hypercortisonism. Role of 25 hydroxyvitamin D and corticosteroid dose
    • R.G. Klein, S.B. Arnaud, J.C. Gallagher, H.F. Deluca, and B.L. Riggs Intestinal calcium absorption in exogenous hypercortisonism. Role of 25-hydroxyvitamin D and corticosteroid dose J Clin Invest 60 1977 253 259 (Pubitemid 8145163)
    • (1977) Journal of Clinical Investigation , vol.60 , Issue.1 , pp. 253-259
    • Klein, R.G.1    Arnaud, S.B.2    Gallagher, J.C.3
  • 21
    • 73649118537 scopus 로고    scopus 로고
    • Functional effects of polymorphisms in the human gene encoding 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1): A sequence variant at the translation start of 11 beta-HSD1 alters enzyme levels
    • E.L. Malavasi, V. Kelly, N. Nath, A. Gambineri, R.S. Dakin, U. Pagotto, R. Pasquali, B.R. Walker, and K.E. Chapman Functional effects of polymorphisms in the human gene encoding 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1): a sequence variant at the translation start of 11 beta-HSD1 alters enzyme levels Endocrinology 151 2010 195 202
    • (2010) Endocrinology , vol.151 , pp. 195-202
    • Malavasi, E.L.1    Kelly, V.2    Nath, N.3    Gambineri, A.4    Dakin, R.S.5    Pagotto, U.6    Pasquali, R.7    Walker, B.R.8    Chapman, K.E.9
  • 22
    • 28444475613 scopus 로고    scopus 로고
    • Polymorphisms in the gene encoding 11B-hydroxysteroid dehydrogenase type 1 (HSD11B1) and lifetime cognitive change
    • DOI 10.1016/j.neulet.2005.09.047, PII S0304394005011055
    • I.J. Deary, C. Hayward, P.A. Permana, S. Nair, L.J. Whalley, J.M. Starr, K.E. Chapman, B.R. Walker, and J.R. Seckl Polymorphisms in the gene encoding 11B-hydroxysteroid dehydrogenase type 1 (HSD11B1) and lifetime cognitive change Neurosci Lett 393 2006 74 77 (Pubitemid 41739657)
    • (2006) Neuroscience Letters , vol.393 , Issue.1 , pp. 74-77
    • Deary, I.J.1    Hayward, C.2    Permana, P.A.3    Nair, S.4    Whalley, L.J.5    Starr, J.M.6    Chapman, K.E.7    Walker, B.R.8    Seckl, J.R.9
  • 23
    • 26244456538 scopus 로고    scopus 로고
    • Genotypes at 11β-hydroxysteroid dehydrogenase type 11B1 and hexose-6-phosphate dehydrogenase loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample
    • DOI 10.1210/jc.2005-0942
    • P.C. White Genotypes at 11beta-hydroxysteroid dehydrogenase type 11B1 and hexose-6-phosphate dehydrogenase loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample J Clin Endocrinol Metab 90 2005 5880 5883 (Pubitemid 41415506)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.10 , pp. 5880-5883
    • White, P.C.1
  • 24
    • 45749090180 scopus 로고    scopus 로고
    • Tumour necrosis factor superfamily member 11 gene promoter polymorphisms modulate promoter activity and influence bone mineral density in postmenopausal women with osteoporosis
    • DOI 10.1677/JME-08-0003
    • S. Mencej, O.M. Albagha, J. Prezelj, T. Kocjan, and J. Marc Tumour necrosis factor superfamily member 11 gene promoter polymorphisms modulate promoter activity and influence bone mineral density in postmenopausal women with osteoporosis J Mol Endocrinol 40 2008 273 279 (Pubitemid 351865035)
    • (2008) Journal of Molecular Endocrinology , vol.40 , Issue.5-6 , pp. 273-279
    • Mencej, S.1    Albagha, O.M.E.2    Prezelj, J.3    Kocjan, T.4    Marc, J.5
  • 25
    • 84856330183 scopus 로고    scopus 로고
    • Functional polymorphisms within the TNFRSF11B (osteoprotegerin) gene increase the risk for low bone mineral density
    • C. Vidal, R. Formosa, and A. Xuereb-Anastasi Functional polymorphisms within the TNFRSF11B (osteoprotegerin) gene increase the risk for low bone mineral density J Mol Endocrinol 47 2011 327 333
    • (2011) J Mol Endocrinol , vol.47 , pp. 327-333
    • Vidal, C.1    Formosa, R.2    Xuereb-Anastasi, A.3
  • 26
    • 0034743960 scopus 로고    scopus 로고
    • Modulation of 11β-hydroxysteroid dehydrogenase isozymes by proinflammatory cytokines in osteoblasts: An autocrine switch from glucocorticoid inactivation to activation
    • M.S. Cooper, I. Bujalska, E. Rabbitt, E.A. Walker, R. Bland, M.C. Sheppard, M. Hewison, and P.M. Stewart Modulation of 11beta-hydroxysteroid dehydrogenase isozymes by proinflammatory cytokines in osteoblasts: an autocrine switch from glucocorticoid inactivation to activation J Bone Miner Res 16 2001 1037 1044 (Pubitemid 32467147)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.6 , pp. 1037-1044
    • Cooper, M.S.1    Bujalska, I.2    Rabbitt, E.3    Walker, E.A.4    Bland, R.5    Sheppard, M.C.6    Hewison, M.7    Stewart, P.M.8
  • 28
    • 0032588826 scopus 로고    scopus 로고
    • Characterization of 11β-hydroxysteroid dehydrogenase activity and corticosteroid receptor expression in human osteosarcoma cell lines
    • DOI 10.1677/joe.0.1610455
    • R. Bland, C.A. Worker, B.S. Noble, L.J. Eyre, I.J. Bujalska, M.C. Sheppard, P.M. Stewart, and M. Hewison Characterization of 11beta-hydroxysteroid dehydrogenase activity and corticosteroid receptor expression in human osteosarcoma cell lines J Endocrinol 161 1999 455 464 (Pubitemid 29278801)
    • (1999) Journal of Endocrinology , vol.161 , Issue.3 , pp. 455-464
    • Bland, R.1    Worker, C.A.2    Noble, B.S.3    Eyre, L.J.4    Bujalska, J.I.5    Sheppard, M.C.6    Stewart, P.M.7    Hewison, M.8
  • 29
    • 0032716911 scopus 로고    scopus 로고
    • Glucocorticoid activity, inactivity and the osteoblast
    • M.S. Cooper, M. Hewison, and P.M. Stewart Glucocorticoid activity, inactivity and the osteoblast J Endocrinol 163 1999 159 164
    • (1999) J Endocrinol , vol.163 , pp. 159-164
    • Cooper, M.S.1    Hewison, M.2    Stewart, P.M.3
  • 30
    • 33646874547 scopus 로고    scopus 로고
    • A novel promoter for the 11β-hydroxysteroid dehydrogenase type 1 gene is active in lung and is C/EBPα independent
    • DOI 10.1210/en.2005-1621
    • C. Bruley, V. Lyons, A.G. Worsley, M.D. Wilde, G.D. Darlington, N.M. Morton, J.R. Seckl, and K.E. Chapman A novel promoter for the 11beta-hydroxysteroid dehydrogenase type 1 gene is active in lung and is C/EBPalpha independent Endocrinology 147 2006 2879 2885 (Pubitemid 43778692)
    • (2006) Endocrinology , vol.147 , Issue.6 , pp. 2879-2885
    • Bruley, C.1    Lyons, V.2    Worsley, A.G.F.3    Wilde, M.D.4    Darlington, G.D.5    Morton, N.M.6    Seckl, J.R.7    Chapman, K.E.8
  • 31
    • 50649118544 scopus 로고    scopus 로고
    • Glucocorticoid regulation of the promoter of 11beta-hydroxysteroid dehydrogenase type 1 is indirect and requires CCAAT/enhancer-binding protein-beta
    • S. Sai, C.L. Esteves, V. Kelly, Z. Michailidou, K. Anderson, A.P. Coll, Y. Nakagawa, T. Ohzeki, J.R. Seckl, and K.E. Chapman Glucocorticoid regulation of the promoter of 11beta-hydroxysteroid dehydrogenase type 1 is indirect and requires CCAAT/enhancer-binding protein-beta Mol Endocrinol 22 2008 2049 2060
    • (2008) Mol Endocrinol , vol.22 , pp. 2049-2060
    • Sai, S.1    Esteves, C.L.2    Kelly, V.3    Michailidou, Z.4    Anderson, K.5    Coll, A.P.6    Nakagawa, Y.7    Ohzeki, T.8    Seckl, J.R.9    Chapman, K.E.10
  • 32
    • 0034730762 scopus 로고    scopus 로고
    • C/EBP regulates hepatic transcription of 11beta-hydroxysteroid dehydrogenase type 1. A novel mechanism for cross-talk between the C/EBP and glucocorticoid signaling pathways
    • L.J. Williams, V. Lyons, I. MacLeod, V. Rajan, G.J. Darlington, V. Poli, J.R. Seckl, and K.E. Chapman C/EBP regulates hepatic transcription of 11beta-hydroxysteroid dehydrogenase type 1. A novel mechanism for cross-talk between the C/EBP and glucocorticoid signaling pathways J Biol Chem 275 2000 30232 30239
    • (2000) J Biol Chem , vol.275 , pp. 30232-30239
    • Williams, L.J.1    Lyons, V.2    MacLeod, I.3    Rajan, V.4    Darlington, G.J.5    Poli, V.6    Seckl, J.R.7    Chapman, K.E.8
  • 33
    • 36349012396 scopus 로고    scopus 로고
    • Role of glucocorticoid receptor and CCAAT/enhancer-binding protein α in the feed-forward induction of 11β-hydroxysteroid dehydrogenase type 1 expression by cortisol in human amnion fibroblasts
    • DOI 10.1677/JOE-07-0303
    • Z. Yang, C. Guo, P. Zhu, W. Li, L. Myatt, and K. Sun Role of glucocorticoid receptor and CCAAT/enhancer-binding protein alpha in the feed-forward induction of 11beta-hydroxysteroid dehydrogenase type 1 expression by cortisol in human amnion fibroblasts J Endocrinol 195 2007 241 253 (Pubitemid 350143104)
    • (2007) Journal of Endocrinology , vol.195 , Issue.2 , pp. 241-253
    • Yang, Z.1    Guo, C.2    Zhu, P.3    Li, W.4    Myatt, L.5    Sun, K.6
  • 34
    • 33748771458 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins (C/EBPs) regulate the basal and cAMP-induced transcription of the human 11β-hydroxysteroid dehydrogenase encoding gene in adipose cells
    • DOI 10.1016/j.biochi.2006.05.020, PII S0300908406001076
    • J. Gout, J. Tirard, C. Thevenon, J.P. Riou, M. Begeot, and D. Naville CCAAT/enhancer-binding proteins (C/EBPs) regulate the basal and cAMP-induced transcription of the human 11beta-hydroxysteroid dehydrogenase encoding gene in adipose cells Biochimie 88 2006 1115 1124 (Pubitemid 44415208)
    • (2006) Biochimie , vol.88 , Issue.9 , pp. 1115-1124
    • Gout, J.1    Tirard, J.2    Thevenon, C.3    Riou, J.-P.4    Begeot, M.5    Naville, D.6
  • 35
    • 79957562818 scopus 로고    scopus 로고
    • Analysis of alternative promoter usage in expression of HSD11B1 including the development of a transcript-specific quantitative real-time PCR method
    • C.A. Staab, J.P. Stegk, S. Haenisch, E. Neiss, K. Kobsch, B. Ebert, I. Cascorbi, and E. Maser Analysis of alternative promoter usage in expression of HSD11B1 including the development of a transcript-specific quantitative real-time PCR method Chem Biol Interact 191 2011 104 112
    • (2011) Chem Biol Interact , vol.191 , pp. 104-112
    • Staab, C.A.1    Stegk, J.P.2    Haenisch, S.3    Neiss, E.4    Kobsch, K.5    Ebert, B.6    Cascorbi, I.7    Maser, E.8
  • 36
    • 4043086277 scopus 로고    scopus 로고
    • Sensitivity of bone to glucocorticoids
    • DOI 10.1042/CS20040070
    • M.S. Cooper Sensitivity of bone to glucocorticoids Clin Sci (Lond) 107 2004 111 123 (Pubitemid 39070927)
    • (2004) Clinical Science , vol.107 , Issue.2 , pp. 111-123
    • Cooper, M.S.1
  • 37
    • 33749531907 scopus 로고    scopus 로고
    • T-1213C polymorphism of estrogen receptor beta is associated with low bone mineral density and osteoporotic fractures
    • DOI 10.1016/j.bone.2006.04.029, PII S8756328206004777
    • A.W. Kung, B.M. Lai, M.Y. Ng, V. Chan, and P.C. Sham T-1213C polymorphism of estrogen receptor beta is associated with low bone mineral density and osteoporotic fractures Bone 39 2006 1097 1106 (Pubitemid 44528372)
    • (2006) Bone , vol.39 , Issue.5 , pp. 1097-1106
    • Kung, A.W.C.1    Lai, B.M.H.2    Ng, M.Y.M.3    Chan, V.4    Sham, P.C.5
  • 39
    • 67650721444 scopus 로고    scopus 로고
    • Promoter and intron 1 polymorphisms of COL1A1 interact to regulate transcription and susceptibility to osteoporosis
    • H. Jin, R.J. Van't Hof, O.M. Albagha, and S.H. Ralston Promoter and intron 1 polymorphisms of COL1A1 interact to regulate transcription and susceptibility to osteoporosis Hum Mol Genet 18 2009 2729 2738
    • (2009) Hum Mol Genet , vol.18 , pp. 2729-2738
    • Jin, H.1    Van'T Hof, R.J.2    Albagha, O.M.3    Ralston, S.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.