Polymorphisms in the gene encoding 11B-hydroxysteroid dehydrogenase type 1 (HSD11B1) and lifetime cognitive change

Neuroscience Letters

Volumn 393, Issue 1, 2006, Pages 74-77

  Deary, Ian J ^a   Hayward, Caroline ^b   Permana, Paska A ^c   Nair, Saraswathy ^d   Whalley, Lawrence J ^e   Starr, John M ^a   Chapman, Karen E ^f   Walker, Brian R ^f   Seckl, Jonathan R ^f  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c CARL T HAYDEN VA MEDICAL CENTER   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^e UNIVERSITY OF ABERDEEN   (United Kingdom)

^f UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

11B hydroxysteroid dehydrogenase type 1; Cognitive ageing; HSD11B1; IQ; Verbal reasoning

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE;

ADULT; AGED; AGING; ARTICLE; CHILD; COGNITION; DNA POLYMORPHISM; FEMALE; GENETIC CODE; GENETIC VARIABILITY; HEALTH SURVEY; HUMAN; INTELLIGENCE QUOTIENT; MAJOR CLINICAL STUDY; MALE; MENTAL TEST; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; VALIDATION PROCESS;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; AGED; AGING; COGNITION; COHORT STUDIES; DEMOGRAPHY; FEMALE; HUMANS; MALE; POLYMORPHISM, GENETIC; TIME FACTORS;

EID: 28444475613     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.09.047     Document Type: Article

References (24)

1. I.J. Deary, M.C. Whiteman, J.M. Starr, L.J. Whalley, and H.C. Fox The impact of childhood intelligence on later life: following up the Scottish Mental Surveys of 1932 and 1947 J. Pers. Soc. Psychol. 86 2004 130 147
2. V.M. de Bruin, M.C. Viera, M.N. Rocha, and G.S. Viana Cortisol and dehydroepiandrosterone sulfate plasma levels and their relationship to aging, cognitive function, and dementia Brain Cogn. 50 2002 316 323
3. E.R. de Kloet Brain corticosteroid receptor balance and homeostatic control Front. Neuroendocrinol. 12 1991 95 164
4. D.J.F. de Quervain, R. Poirier, M.A. Wollmer, L.M. Grimaldi, M. Tsolaki, J.R. Streffer, C. Hock, R.M. Nitsch, M.H. Mohajeri, and A. Papassotiropoulos Glucocorticoid-related genetic susceptibility for Alzheimer's disease Hum. Mol. Genet. 13 2004 47 52
5. N. Draper, S.M. Echwald, G.G. Lavery, E.A. Walker, R. Fraser, E. Davies, T.I. Sorensen, A. Astrup, J. Adamski, M. Hewison, J.M. Connell, O. Pedersen, and P.M. Stewart Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocortocoid metabolism J. Clin. Endocrinol. Metab. 87 2002 4984 4990
6. N. Draper, E.A. Walker, I.J. Bujalska, J.W. Tomlinson, S.M. Chalder, W. Arlt, G.G. Lavery, O. Bedendo, D.W. Ray, I. Laing, E. Malunowicz, P.C. White, M. Hewison, P.J. Mason, J.M. Connell, C.H. Shackleton, and P.M. Stewart Mutations in the genes coding 11β-hydroxysteroid dehysrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency Nat. Genet. 34 2003 434 439
7. P.W. Franks, W.C. Knowler, S. Nair, J. Koska, Y.H. Lee, R.S. Lindsay, B.R. Walker, H.C. Looker, P.A. Permana, P.A. Tataranni, and R.L. Hanson Interaction between an 11bHSD1 gene variant and birth era modifies risk of hypertension in Pima Indians Hypertension 44 2004 681 688
8. A.M. Issa, W. Rowe, S. Gauthier, and M.J. Meaney Hypothalamic-pituitary- adrenal activity in aged, cognitively impaired and cognitively unimpaired rats J. Neurosci. 10 1990 3247 3254
9. V. Lakshmi, R.R. Sakai, B.S. McEwen, and C. Monder Regional distribution of 11β-hydroxysteroid dehydrogenase in rat brain Endocrinology 128 1991 1741 1748
10. P.W. Landfield, J. Waymire, and G. Lynch Hippocampal aging and adrenocorticoids: a quantitative correlation Science 202 1978 1098 1102
11. S.J. Lupien, M. deLeon, S. deSanti, A. Convit, C. Tarshish, M. Thakur, B.S. McEwen, R.L. Hauger, and M.J. Meaney Cortisol levels during human aging predict hippocampal atrophy and memory deficits Nat. Neurosci. 1 1998 69 73
12. B.S. McEwen Stress and the aging hippocampus Front. Neuroendocrinol. 20 1999 49 70
13. M.J. Meaney, D.H. Aitken, C. van Berkel, S. Bhatnagar, and R.M. Sapolsky Effect of neonatal handling on age-related impairments associated with the hippocampus Science 239 1988 766 768
14. M.J. Meaney, D. O'Donnell, W. Rowe, B. Tannenbaum, A. Steverman, M. Walker, N.P.V. Nair, and S. Lupien Individual differences in hypothalamic-pituitary-adrenal activity in later life and hippocampal aging Exp. Gerontol. 30 1995 229 251
15. T.P. Miller, J. Taylor, S. Rogerson, M. Mauricio, Q. Kennedy, A. Schatzberg, J. Tinklenberg, and J. Yesavage Cognitive and noncognitive symptoms in dementia patients: relationship to cortisol and dehydroepiandrosterone Int. Psychogeriatr. 10 1998 85 96
16. M.-P. Moisan, J.R. Seckl, and C.R.W. Edwards 11β-hydroxysteroid dehydrogenase bioactivity and messenger RNA expression in rat forebrain: localization in hypothalamus, hippocampus and cortex Endocrinology 127 1990 1450 1455
17. S. Nair, Y.H. Lee, R.S. Lindsay, B.R. Walker, P.A. Tataranni, C. Bogardus, L.J. Baier, and P.A. Permana The 11beta hydroxysteroid dehydrogenase type 1 gene: genetic polymorphisms are associated with type 2 diabetes in Pima indians independently of obesity and expression in adipocyte and muscle Diabetologia 47 2004 1088 1095
18. T.C. Sandeep, J.L. Yau, A.M. MacLullich, J. Noble, I.J. Deary, B.R. Walker, and J.R. Seckl Effects of 11beta-hydroxysteroid dehydrogenase inhibition on cognitive function in healthy elderly men and patients with type 2 diabetes Proc. Natl. Acad. Sci. U.S.A. 101 2004 6734 6739
19. Scottish Council for Research in Education The Intelligence of Scottish Children: A National Survey of an Age-Group 1933 University of London Press London
20. J.R. Seckl, and T. Olsson Glucocorticoids and the age-impaired hippocampus: cause or effect? J. Endocrinol. 145 1995 201 211
21. J.R. Seckl, and B.R. Walker 11β-hydroxysteroid dehydrogenase type 1: a tissue-specific amplifier of glucocorticoid action Endocrinology 142 2001 1371 1376
22. J.R. Seckl, and B.R. Walker 11beta-hydroxysteroid dehydrogenase type 1 as a modulator of glucocorticoid action: from metabolism to memory Trends Endocrinol. Metab. 15 2004 418 424
23. J.L.W. Yau, J. Noble, C. Hibberd, W.B. Rowe, M.J. Meaney, R.G.M. Morris, and J.R. Seckl Chronic treatment with the antidepressant amitriptyline prevents impairments in water maze learning in aging rats J. Neurosci. 22 2002 1436 1442
24. J.L.W. Yau, J. Noble, C.J. Kenyon, C. Hibberd, Y. Kotelevtsev, J.J. Mullins, and J.R. Seckl Lack of tissue glucocorticoid reactivation in 11β-hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments Proc. Natl. Acad. Sci. U.S.A. 98 2001 4716 4721