Promoter and intron 1 polymorphisms of COL1A1 interact to regulate transcription and susceptibility to osteoporosis

Human Molecular Genetics

Volumn 18, Issue 15, 2009, Pages 2729-2738

  Jin, Huilin ^a   van't hof, Rob J ^a   Albagha, Omar M E ^a   Ralston, Stuart H ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; DNA; GUANINE; NUCLEAR MATRIX PROTEIN; NUCLEAR MATRIX PROTEIN 4; RNA POLYMERASE II; THREONINE; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; BINDING AFFINITY; BINDING SITE; BONE DENSITY; CAUCASIAN; CELL DIFFERENTIATION; CELL FUNCTION; CHROMATIN IMMUNOPRECIPITATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DNA FLANKING REGION; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE INSERTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; HUMAN CELL; INTRON; OSTEOBLAST; OSTEOPOROSIS; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; BONE DENSITY; CELL LINE, TUMOR; COLLAGEN TYPE I; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTRONS; MOLECULAR SEQUENCE DATA; OSTEOPOROSIS; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 67650721444     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp205     Document Type: Article

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