메뉴 건너뛰기




Volumn 32, Issue 9, 2011, Pages 1388-1395

CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: Effects on motility, migration and p63 expression

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CONOTOXIN MII; CALCIUM; NICOTINE; NICOTINIC RECEPTOR ALPHA4; NICOTINIC RECEPTOR ALPHA5; PROTEIN P120; PROTEIN P63; PROTEIN ZO1; RNA; UNCLASSIFIED DRUG;

EID: 80052423131     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr090     Document Type: Article
Times cited : (41)

References (38)
  • 1
    • 33847638137 scopus 로고    scopus 로고
    • Estimates of the cancer incidence and mortality in Europe in 2006
    • Ferlay,J. et al. (2007) Estimates of the cancer incidence and mortality in Europe in 2006. Ann. Oncol., 18, 581-592.
    • (2007) Ann. Oncol. , vol.18 , pp. 581-592
    • Ferlay, J.1
  • 2
    • 6944231024 scopus 로고    scopus 로고
    • The cumulative risk of lung cancer among current, ex- and never-smokers in European men
    • Crispo,A. et al. (2004) The cumulative risk of lung cancer among current, ex- and never-smokers in European men. Br. J. Cancer, 91, 1280-1286.
    • (2004) Br. J. Cancer , vol.91 , pp. 1280-1286
    • Crispo, A.1
  • 3
    • 42649091460 scopus 로고    scopus 로고
    • Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25
    • Amos,C.I. et al. (2008) Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat. Genet., 40, 616-622.
    • (2008) 1. Nat. Genet. , vol.40 , pp. 616-622
    • Amos, C.I.1
  • 4
    • 41649103682 scopus 로고    scopus 로고
    • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
    • Hung,R.J. et al. (2008) A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature, 452, 633-637.
    • (2008) Nature , vol.452 , pp. 633-637
    • Hung, R.J.1
  • 5
    • 41649103052 scopus 로고    scopus 로고
    • A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
    • Thorgeirsson,T.E. et al. (2008) A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature, 452, 638-642.
    • (2008) Nature , vol.452 , pp. 638-642
    • Thorgeirsson, T.E.1
  • 6
    • 63449101907 scopus 로고    scopus 로고
    • A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci
    • Pillai,S.G. et al. (2009) A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet., 5, e1000421.
    • (2009) PLoS Genet , vol.5
    • Pillai, S.G.1
  • 7
    • 58949096687 scopus 로고    scopus 로고
    • Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese
    • Shiraishi,K. et al. (2009) Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese. Carcinogenesis, 30, 65-70.
    • (2009) Carcinogenesis , vol.30 , pp. 65-70
    • Shiraishi, K.1
  • 8
    • 58249113980 scopus 로고    scopus 로고
    • Mammalian nicotinic acetylcholine receptors: from structure to function
    • Albuquerque,E.X. et al. (2009) Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol. Rev., 89, 73-120.
    • (2009) Physiol. Rev. , vol.89 , pp. 73-120
    • Albuquerque, E.X.1
  • 9
    • 33646800564 scopus 로고    scopus 로고
    • Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells
    • Arredondo,J. et al. (2006) Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells. Cancer Biol. Ther., 5, 511-517.
    • (2006) Cancer Biol. Ther. , vol.5 , pp. 511-517
    • Arredondo, J.1
  • 11
    • 34249284421 scopus 로고    scopus 로고
    • Nitrosamines as nicotinic receptor ligands
    • Schuller,H.M. (2007) Nitrosamines as nicotinic receptor ligands. Life Sci., 80, 2274-2280.
    • (2007) Life Sci , vol.80 , pp. 2274-2280
    • Schuller, H.M.1
  • 12
    • 34249983499 scopus 로고    scopus 로고
    • Recent progress in understanding the non-neuronal cholinergic system in humans
    • Grando,S.A. et al. (2007) Recent progress in understanding the non-neuronal cholinergic system in humans. Life Sci., 80, 2181-2185.
    • (2007) Life Sci , vol.80 , pp. 2181-2185
    • Grando, S.A.1
  • 13
    • 60749101452 scopus 로고    scopus 로고
    • Is cancer triggered by altered signalling of nicotinic acetylcholine receptors?
    • Schuller,H.M. (2009) Is cancer triggered by altered signalling of nicotinic acetylcholine receptors? Nat. Rev. Cancer, 9, 195-205.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 195-205
    • Schuller, H.M.1
  • 14
    • 33644793144 scopus 로고    scopus 로고
    • Cholinergic control of epidermal cohesion
    • Grando,S.A. (2006) Cholinergic control of epidermal cohesion. Exp. Dermatol., 15, 265-282.
    • (2006) Exp. Dermatol. , vol.15 , pp. 265-282
    • Grando, S.A.1
  • 15
    • 2042443069 scopus 로고    scopus 로고
    • Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells
    • Proskocil,B.J. et al. (2004) Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells. Endocrinology, 145, 2498-2506.
    • (2004) Endocrinology , vol.145 , pp. 2498-2506
    • Proskocil, B.J.1
  • 16
    • 30344476073 scopus 로고    scopus 로고
    • alpha3alpha5beta2-Nicotinic acetylcholine receptor contributes to the wound repair of the respiratory epithelium by modulating intracellular calcium in migrating cells
    • Tournier,J.M. et al. (2006) alpha3alpha5beta2-Nicotinic acetylcholine receptor contributes to the wound repair of the respiratory epithelium by modulating intracellular calcium in migrating cells. Am. J. Pathol., 168, 55-68.
    • (2006) Am. J. Pathol. , vol.168 , pp. 55-68
    • Tournier, J.M.1
  • 17
    • 80052414562 scopus 로고    scopus 로고
    • {alpha}7 Nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation
    • Maouche,K. et al. (2009) {alpha}7 Nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation. Am. J. Pathol., 168, 55-68.
    • (2009) Am. J. Pathol. , vol.168 , pp. 55-68
    • Maouche, K.1
  • 18
    • 1842639461 scopus 로고    scopus 로고
    • Lysyl oxidase-like and lysyl oxidase are present in the dermis and epidermis of a skin equivalent and in human skin and are associated to elastic fibers
    • Noblesse,E. et al. (2004) Lysyl oxidase-like and lysyl oxidase are present in the dermis and epidermis of a skin equivalent and in human skin and are associated to elastic fibers. J. Invest. Dermatol., 122, 621-630.
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 621-630
    • Noblesse, E.1
  • 19
    • 34250307900 scopus 로고    scopus 로고
    • Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers
    • Lam,D.C. et al. (2007) Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers. Cancer Res., 67, 4638-4647.
    • (2007) Cancer Res , vol.67 , pp. 4638-4647
    • Lam, D.C.1
  • 20
    • 0029871748 scopus 로고    scopus 로고
    • A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors
    • Cartier,G.E. et al. (1996) A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors. J. Biol. Chem., 271, 7522-7528.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7522-7528
    • Cartier, G.E.1
  • 21
    • 0028178802 scopus 로고
    • Neuronal acetylcholine receptors that bind alphabungarotoxin with high affinity function as ligand-gated ion channels
    • Zhang,Z.W. et al. (1994) Neuronal acetylcholine receptors that bind alphabungarotoxin with high affinity function as ligand-gated ion channels. Neuron, 12, 167-177.
    • (1994) Neuron , vol.12 , pp. 167-177
    • Zhang, Z.W.1
  • 22
    • 33750475626 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR data analysis: current concepts and the novel "gene expression's CT difference" formula
    • Schefe,J.H. et al. (2006) Quantitative real-time RT-PCR data analysis: current concepts and the novel "gene expression's CT difference" formula. J. Mol. Med., 84, 901-910.
    • (2006) J. Mol. Med. , vol.84 , pp. 901-910
    • Schefe, J.H.1
  • 23
    • 77049088523 scopus 로고    scopus 로고
    • Characterisation of human fibroblasts as keratinocyte feeder layer using p63 isoforms status
    • Auxenfans,C. et al. (2009) Characterisation of human fibroblasts as keratinocyte feeder layer using p63 isoforms status. Biomed. Mater. Eng., 19, 365-372.
    • (2009) Biomed. Mater. Eng. , vol.19 , pp. 365-372
    • Auxenfans, C.1
  • 24
    • 58149390632 scopus 로고    scopus 로고
    • Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines
    • Dasgupta,P. et al. (2009) Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines. Int. J. Cancer, 124, 36-45.
    • (2009) Int. J. Cancer , vol.124 , pp. 36-45
    • Dasgupta, P.1
  • 25
    • 33847023954 scopus 로고    scopus 로고
    • TAp63 and DeltaNp63 in cancer and epidermal development
    • Candi,E. et al. (2007) TAp63 and DeltaNp63 in cancer and epidermal development. Cell Cycle, 6, 274-285.
    • (2007) Cell Cycle , vol.6 , pp. 274-285
    • Candi, E.1
  • 26
    • 33847056673 scopus 로고    scopus 로고
    • p63, cell adhesion and survival
    • Carroll,D.K. et al. (2007) p63, cell adhesion and survival. Cell Cycle, 6, 255-261.
    • (2007) Cell Cycle , vol.6 , pp. 255-261
    • Carroll, D.K.1
  • 27
    • 2942677539 scopus 로고    scopus 로고
    • Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium
    • Daniely,Y. et al. (2004) Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am. J. Physiol. Cell Physiol., 287, C171-C181.
    • (2004) Am. J. Physiol. Cell Physiol. , vol.287
    • Daniely, Y.1
  • 28
    • 0034625043 scopus 로고    scopus 로고
    • AIS is an oncogene amplified in squamous cell carcinoma
    • Hibi,K. et al. (2000) AIS is an oncogene amplified in squamous cell carcinoma. Proc. Natl Acad. Sci. U S A, 97, 5462-5467.
    • (2000) Proc. Natl Acad. Sci. U S A , vol.97 , pp. 5462-5467
    • Hibi, K.1
  • 29
    • 34547112583 scopus 로고    scopus 로고
    • Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture
    • Roman,S. et al. (2007) Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture. Am. J. Physiol. Gastrointest. Liver Physiol., 293, G45-G53.
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.293
    • Roman, S.1
  • 30
    • 77956627856 scopus 로고    scopus 로고
    • Intraepithelial p63-dependent expression of distinct components of cell adhesion complexes in normal esophageal mucosa and squamous cell carcinoma
    • Thepot,A. et al. (2010) Intraepithelial p63-dependent expression of distinct components of cell adhesion complexes in normal esophageal mucosa and squamous cell carcinoma. Int. J. Cancer, 127, 2051-2062.
    • (2010) Int. J. Cancer , vol.127 , pp. 2051-2062
    • Thepot, A.1
  • 31
    • 79953224060 scopus 로고    scopus 로고
    • Genetics of lung-cancer susceptibility
    • Brennan,P. et al. (2010) Genetics of lung-cancer susceptibility. Lancet Oncol., 12, 399-408.
    • (2010) Lancet Oncol , vol.12 , pp. 399-408
    • Brennan, P.1
  • 32
    • 77951766653 scopus 로고    scopus 로고
    • Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals
    • Lips,E.H. et al. (2010) Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals. Int. J. Epidemiol., 39, 563-577.
    • (2010) Int. J. Epidemiol. , vol.39 , pp. 563-577
    • Lips, E.H.1
  • 33
    • 34250705693 scopus 로고    scopus 로고
    • Beta-catenin and ZO-1: shuttle molecules involved in tumor invasion-associated epithelial-mesenchymal transition processes
    • Polette,M. et al. (2007) Beta-catenin and ZO-1: shuttle molecules involved in tumor invasion-associated epithelial-mesenchymal transition processes. Cells Tissues Organs, 185, 61-65.
    • (2007) Cells Tissues Organs , vol.185 , pp. 61-65
    • Polette, M.1
  • 34
    • 77950809864 scopus 로고    scopus 로고
    • Aberrant DNA methylation links cancer susceptibility locus 15q25.1 to apoptotic regulation and lung cancer
    • Paliwal,A. et al. (2010) Aberrant DNA methylation links cancer susceptibility locus 15q25.1 to apoptotic regulation and lung cancer. Cancer Res., 70, 2779-2788.
    • (2010) Cancer Res. , vol.70 , pp. 2779-2788
    • Paliwal, A.1
  • 35
    • 0037251896 scopus 로고    scopus 로고
    • Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancer
    • Minna,J.D. (2003) Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancer. J. Clin. Invest., 111, 31-33.
    • (2003) J. Clin. Invest. , vol.111 , pp. 31-33
    • Minna, J.D.1
  • 36
    • 63449118690 scopus 로고    scopus 로고
    • Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk
    • Falvella,F.S. et al. (2009) Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk. Clin. Cancer Res., 15, 1837-1842.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 1837-1842
    • Falvella, F.S.1
  • 37
    • 77956578943 scopus 로고    scopus 로고
    • Promoter polymorphisms and transcript levels of nicotinic receptor CHRNA5
    • Falvella,F.S. et al. (2010) Promoter polymorphisms and transcript levels of nicotinic receptor CHRNA5. J. Natl Cancer Inst., 102, 1366-1370.
    • (2010) J. Natl Cancer Inst. , vol.102 , pp. 1366-1370
    • Falvella, F.S.1
  • 38
    • 77952692954 scopus 로고    scopus 로고
    • Nicotine addiction and nicotinic receptors: lessons from genetically modified mice
    • Changeux,J.P. (2010) Nicotine addiction and nicotinic receptors: lessons from genetically modified mice. Nat. Rev. Neurosci., 11, 389-401.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 389-401
    • Changeux, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.