Non-Diabetic Hyperglycemia Exacerbates Disease Severity in Mycobacterium tuberculosis Infected Guinea Pigs

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Podell, Brendan K ^a   Ackart, David F ^a   Kirk, Natalie M ^a   Eck, Sarah P ^a   Bell, Christopher ^a   Basaraba, Randall J ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; FATTY ACID; GLUCOSE; INSULIN; SUCROSE; WATER;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; BACTERIAL STRAIN; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; EXTRAPULMONARY TUBERCULOSIS; FOOD INTAKE; GUINEA PIG; HYPERGLYCEMIA; INSULIN RESISTANCE; LUNG GRANULOMA; LUNG PARENCHYMA; LUNG TUBERCULOSIS; LYMPH NODE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POSTPRANDIAL STATE; SPLEEN;

ANIMALS; BLOOD GLUCOSE; FATTY ACIDS, NONESTERIFIED; GLUCOSE TOLERANCE TEST; GLYCOSYLATION END PRODUCTS, ADVANCED; GUINEA PIGS; HYPERGLYCEMIA; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS;

ANIMALIA; BACTERIA (MICROORGANISMS); CAVIA; MYCOBACTERIUM TUBERCULOSIS;

EID: 84867130200     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046824     Document Type: Article

References (52)

1. Lonnroth K, Castro KG, Chakaya JM, Chauhan LS, Floyd K, et al. (2010) Tuberculosis control and elimination 2010-50: cure, care, and social development. Lancet 375: 1814-1829.
2. Root HF, (1934) Diabetic Coma and Pulmonary Tuberculosis. Trans Am Clin Climatol Assoc 50: 210-217.
3. Sen T, Joshi SR, Udwadia ZF, (2009) Tuberculosis and diabetes mellitus: merging epidemics. J Assoc Physicians India 57: 399-404.
4. Dooley KE, Chaisson RE, (2009) Tuberculosis and diabetes mellitus: convergence of two epidemics. Lancet Infect Dis 9: 737-746.
5. Stevenson CR, Forouhi NG, Roglic G, Williams BG, Lauer JA, et al. (2007) Diabetes and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence. BMC Public Health 7: 234.
6. Shaw JE, Sicree RA, Zimmet PZ, (2010) Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 87: 4-14.
7. Harries AD, Lin Y, Satyanarayana S, Lonnroth K, Li L, et al. (2011) The looming epidemic of diabetes-associated tuberculosis: learning lessons from HIV-associated tuberculosis. Int J Tuberc Lung Dis 15: 1436-1445.
8. Jeon CY, Murray MB, (2008) Diabetes mellitus increases the risk of active tuberculosis: a systematic review of 13 observational studies. PLoS Med 5: e152.
9. Perez-Guzman C, Torres-Cruz A, Villarreal-Velarde H, Salazar-Lezama MA, Vargas MH, (2001) Atypical radiological images of pulmonary tuberculosis in 192 diabetic patients: a comparative study. Int J Tuberc Lung Dis 5: 455-461.
10. Moran A, Harbour DV, Teeter LD, Musser JM, Graviss EA, (2007) Is alcohol use associated with cavitary disease in tuberculosis? Alcohol Clin Exp Res 31: 33-38.
11. Wang JY, Lee LN, Hsueh PR, (2005) Factors changing the manifestation of pulmonary tuberculosis. Int J Tuberc Lung Dis 9: 777-783.
12. Garcia-Rodriguez JF, Alvarez-Diaz H, Lorenzo-Garcia MV, Marino-Callejo A, Fernandez-Rial A, et al. (2011) Extrapulmonary tuberculosis: epidemiology and risk factors. Enferm Infecc Microbiol Clin 29: 502-509.
13. Long R, O'Connor R, Palayew M, Hershfield E, Manfreda J, (1997) Disseminated tuberculosis with and without a miliary pattern on chest radiograph: a clinical-pathologic-radiologic correlation. Int J Tuberc Lung Dis 1: 52-58.
14. Wang CS, Yang CJ, Chen HC, Chuang SH, Chong IW, et al. (2009) Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis. Epidemiol Infect 137: 203-210.
15. Dooley KE, Tang T, Golub JE, Dorman SE, Cronin W, (2009) Impact of diabetes mellitus on treatment outcomes of patients with active tuberculosis. Am J Trop Med Hyg 80: 634-639.
16. Restrepo BI, Fisher-Hoch SP, Smith B, Jeon S, Rahbar MH, et al. (2008) Mycobacterial clearance from sputum is delayed during the first phase of treatment in patients with diabetes. Am J Trop Med Hyg 79: 541-544.
17. Leung CC, Lam TH, Chan WM, Yew WW, Ho KS, et al. (2008) Diabetic control and risk of tuberculosis: a cohort study. Am J Epidemiol 167: 1486-1494.
18. Pablos-Mendez A, Blustein J, Knirsch CA, (1997) The role of diabetes mellitus in the higher prevalence of tuberculosis among Hispanics. Am J Public Health 87: 574-579.
19. IDF (2011) International Diabetes Federation Diabetes Atlas: Impaired Glucose Tolerance. 5th ed. Brussels, Belgium.
20. Harries AD, Murray MB, Jeon CY, Ottmani SE, Lonnroth K, et al. (2010) Defining the research agenda to reduce the joint burden of disease from diabetes mellitus and tuberculosis. Trop Med Int Health 15: 659-663.
21. Mao F, Chen T, Zhao Y, Zhang C, Bai B, et al. (2011) Insulin resistance: a potential marker and risk factor for active tuberculosis? Med Hypotheses 77: 66-68.
22. Bierhaus A, Hofmann MA, Ziegler R, Nawroth PP, (1998) AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept. Cardiovasc Res 37: 586-600.
23. Brownlee M, (2005) The pathobiology of diabetic complications: a unifying mechanism. Diabetes 54: 1615-1625.
24. Peppa M, Vlassara H, (2005) Advanced glycation end products and diabetic complications: a general overview. Hormones (Athens) 4: 28-37.
25. Win MT, Yamamoto Y, Munesue S, Saito H, Han D, et al. (2012) Regulation of RAGE for Attenuating Progression of Diabetic Vascular Complications. Exp Diabetes Res 2012: 894605.
26. Ribeiro RT, Lautt WW, Legare DJ, Macedo MP, (2005) Insulin resistance induced by sucrose feeding in rats is due to an impairment of the hepatic parasympathetic nerves. Diabetologia 48: 976-983.
27. Ordway DJ, Shanley CA, Caraway ML, Orme EA, Bucy DS, et al. (2010) Evaluation of standard chemotherapy in the guinea pig model of tuberculosis. Antimicrob Agents Chemother 54: 1820-1833.
28. Borst SE, (2004) The role of TNF-alpha in insulin resistance. Endocrine 23: 177-182.
29. Dhar A, Castillo L, (2011) Insulin resistance in critical illness. Curr Opin Pediatr 23: 269-274.
30. DiAngelo JR, Bland ML, Bambina S, Cherry S, Birnbaum MJ, (2009) The immune response attenuates growth and nutrient storage in Drosophila by reducing insulin signaling. Proc Natl Acad Sci U S A 106: 20853-20858.
31. Ceriello A, Bortolotti N, Motz E, Crescentini A, Lizzio S, et al. (1998) Meal-generated oxidative stress in type 2 diabetic patients. Diabetes Care 21: 1529-1533.
32. Vallerskog T, Martens GW, Kornfeld H, (2010) Diabetic mice display a delayed adaptive immune response to Mycobacterium tuberculosis. J Immunol 184: 6275-6282.
33. Marrero J, Rhee KY, Schnappinger D, Pethe K, Ehrt S, (2010) Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection. Proc Natl Acad Sci U S A 107: 9819-9824.
34. McMurray DN, (2003) Hematogenous reseeding of the lung in low-dose, aerosol-infected guinea pigs: unique features of the host-pathogen interface in secondary tubercles. Tuberculosis (Edinb) 83: 131-134.
35. Palanisamy GS, Smith EE, Shanley CA, Ordway DJ, Orme IM, et al. (2008) Disseminated disease severity as a measure of virulence of Mycobacterium tuberculosis in the guinea pig model. Tuberculosis (Edinb) 88: 295-306.
36. Shang S, Shanley CA, Caraway ML, Orme EA, Henao-Tamayo M, et al. (2012) Drug treatment combined with BCG vaccination reduces disease reactivation in guinea pigs infected with Mycobacterium tuberculosis. Vaccine.
37. Golden MP, Vikram HR, (2005) Extrapulmonary tuberculosis: an overview. Am Fam Physician 72: 1761-1768.
38. Maartens G, Willcox PA, Benatar SR, (1990) Miliary tuberculosis: rapid diagnosis, hematologic abnormalities, and outcome in 109 treated adults. Am J Med 89: 291-296.
39. Goldin A, Beckman JA, Schmidt AM, Creager MA, (2006) Advanced glycation end products: sparking the development of diabetic vascular injury. Circulation 114: 597-605.
40. Harja E, Bu DX, Hudson BI, Chang JS, Shen X, et al. (2008) Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice. J Clin Invest 118: 183-194.
41. Torreggiani M, Liu H, Wu J, Zheng F, Cai W, et al. (2009) Advanced glycation end product receptor-1 transgenic mice are resistant to inflammation, oxidative stress, and post-injury intimal hyperplasia. Am J Pathol 175: 1722-1732.
42. Restrepo BI, Fisher-Hoch SP, Pino PA, Salinas A, Rahbar MH, et al. (2008) Tuberculosis in poorly controlled type 2 diabetes: altered cytokine expression in peripheral white blood cells. Clin Infect Dis 47: 634-641.
43. Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, et al. (2009) Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells. J Pharmacol Exp Ther 330: 89-98.
44. Palanisamy GS, Kirk NM, Ackart DF, Shanley CA, Orme IM, et al. (2011) Evidence for oxidative stress and defective antioxidant response in Guinea pigs with tuberculosis. PLoS One 6: e26254.
45. Degenhardt TP, Thorpe SR, Baynes JW, (1998) Chemical modification of proteins by methylglyoxal. Cell Mol Biol (Noisy-le-grand) 44: 1139-1145.
46. Nemet I, Turk Z, Duvnjak L, Car N, Varga-Defterdarovic L, (2005) Humoral methylglyoxal level reflects glycemic fluctuation. Clin Biochem 38: 379-383.
47. Brownlee M, (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813-820.
48. Yan SF, Ramasamy R, Schmidt AM, (2008) Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications. Nat Clin Pract Endocrinol Metab 4: 285-293.
49. Rachman H, Kim N, Ulrichs T, Baumann S, Pradl L, et al. (2006) Critical role of methylglyoxal and AGE in mycobacteria-induced macrophage apoptosis and activation. PLoS One 1: e29.
50. Somashekar BS, Amin AG, Rithner CD, Troudt J, Basaraba R, et al. (2011) Metabolic profiling of lung granuloma in Mycobacterium tuberculosis infected guinea pigs: ex vivo 1H magic angle spinning NMR studies. J Proteome Res 10: 4186-4195.
51. Cohen-Or I, Katz C, Ron EZ, (2011) AGEs secreted by bacteria are involved in the inflammatory response. PLoS One 6: e17974.
52. Harries AD, Lonnroth K (2011) Collaborative framework for care and control of tuberculosis and diabetes. Geneva: World Health Organziation Press.