-
1
-
-
77951778977
-
Personalized medicine in oncology: The future is now
-
Schilsky R. Personalized medicine in oncology: the future is now. Nat. Rev. Drug Discov. 9(5), 363-366 (2010).
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, Issue.5
, pp. 363-366
-
-
Schilsky, R.1
-
2
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 285(21), 1182-1186 (1971).
-
(1971)
N. Engl. J. Med.
, vol.285
, Issue.21
, pp. 1182-1186
-
-
Folkman, J.1
-
3
-
-
34547095748
-
Pancreatic cancer microenvironment
-
Kleeff J, Beckhove P, Esposito I et al. Pancreatic cancer microenvironment. Int. J. Cancer 121(4), 699-705 (2007).
-
(2007)
Int. J. Cancer
, vol.121
, Issue.4
, pp. 699-705
-
-
Kleeff, J.1
Beckhove, P.2
Esposito, I.3
-
5
-
-
39749114978
-
Hypoxia and metabolism: Hypoxia, DNA repair and genetic instability
-
Bristow R, Hill R. Hypoxia and metabolism: hypoxia, DNA repair and genetic instability. Nat. Rev. Cancer 8(3), 180-192 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, Issue.3
, pp. 180-192
-
-
Bristow, R.1
Hill, R.2
-
6
-
-
2942590732
-
Exploiting tumor hypoxia in cancer treatment
-
Brown J, Wilson W. Exploiting tumor hypoxia in cancer treatment. Nat. Rev. Cancer 4(6), 437-447 (2004).
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.6
, pp. 437-447
-
-
Brown, J.1
Wilson, W.2
-
7
-
-
34748860952
-
Hypoxic radiosensitization: Adored and ignored
-
Overgaard J. Hypoxic radiosensitization: adored and ignored. J. Clin. Oncol. 25(26), 4066-4074 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.26
, pp. 4066-4074
-
-
Overgaard, J.1
-
8
-
-
16644377045
-
Tirapazamine, cisplatin, and radiation versus fluorouracil, cisplatin, and radiation in patients with locally advanced head and neck cancer: A randomized Phase II trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02)
-
Rischin D, Peters L, Fisher R et al. Tirapazamine, cisplatin, and radiation versus fluorouracil, cisplatin, and radiation in patients with locally advanced head and neck cancer: a randomized Phase II trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02). J. Clin. Oncol. 23(1), 79-87 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.1
, pp. 79-87
-
-
Rischin, D.1
Peters, L.2
Fisher, R.3
-
9
-
-
84863338519
-
PI3K/AKT/ mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations
-
Janku F, Wheler J, Westin S et al. PI3K/AKT/ mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations. J. Clin. Oncol. 30(8), 777-782 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.8
, pp. 777-782
-
-
Janku, F.1
Wheler, J.2
Westin, S.3
-
10
-
-
34250326197
-
Pretreatment 18F-FAZA PET predicts success of hypoxiadirected radiochemotherapy using tirapazamine
-
Beck R, Roper B, Carlsen J et al. Pretreatment 18F-FAZA PET predicts success of hypoxiadirected radiochemotherapy using tirapazamine. J. Nucl. Med. 48(6), 973-980 (2007).
-
(2007)
J. Nucl. Med.
, vol.48
, Issue.6
, pp. 973-980
-
-
Beck, R.1
Roper, B.2
Carlsen, J.3
-
11
-
-
33646454133
-
Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: A substudy of Trans-Tasman Radiation Oncology Group Study 98.02
-
Rischin D, Hicks R, Fisher R et al. Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: a substudy of Trans-Tasman Radiation Oncology Group Study 98.02. J. Clin. Oncol. 24(13), 2098-2104 (2006).
-
(2006)
J. Clin. Oncol.
, vol.24
, Issue.13
, pp. 2098-2104
-
-
Rischin, D.1
Hicks, R.2
Fisher, R.3
-
12
-
-
0030801375
-
Heterogeneity of polarographic oxygen tension measurements in cervix cancer: An evaluation of within and between tumor variability, probe position, and track depth
-
Wong R, Fyles A, Milosevic M, Pintilie M, Hill R. Heterogeneity of polarographic oxygen tension measurements in cervix cancer: an evaluation of within and between tumor variability, probe position, and track depth. Int. J. Radiat. Oncol. Biol. Phys. 39(2), 405-412 (1997).
-
(1997)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.39
, Issue.2
, pp. 405-412
-
-
Wong, R.1
Fyles, A.2
Milosevic, M.3
Pintilie, M.4
Hill, R.5
-
13
-
-
36248948574
-
Effect of distributional heterogeneity on the analysis of tumor hypoxia based on carbonic anhydrase IX
-
Iakovlev V, Pintilie M, Morrison A, Fyles A, Hill R, Hedley D. Effect of distributional heterogeneity on the analysis of tumor hypoxia based on carbonic anhydrase IX. Lab. Invest. 87(12), 1206-1217 (2007).
-
(2007)
Lab. Invest.
, vol.87
, Issue.12
, pp. 1206-1217
-
-
Iakovlev, V.1
Pintilie, M.2
Morrison, A.3
Fyles, A.4
Hill, R.5
Hedley, D.6
-
14
-
-
63049084944
-
Heterogeneity and power in clinical biomarker studies
-
Pintilie M, Iakovlev V, Fyles A, Hedley D, Milosevic M, Hill R. Heterogeneity and power in clinical biomarker studies. J. Clin. Oncol. 27(9), 1517-1521 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.9
, pp. 1517-1521
-
-
Pintilie, M.1
Iakovlev, V.2
Fyles, A.3
Hedley, D.4
Milosevic, M.5
Hill, R.6
-
15
-
-
0038523737
-
Tumor hypoxia at the micro-regional level: Clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers
-
Bussink J, Kaanders J, Van Der Kogel A. Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers. Radiother. Oncol. 67(1), 3-15 (2003).
-
(2003)
Radiother. Oncol.
, vol.67
, Issue.1
, pp. 3-15
-
-
Bussink, J.1
Kaanders, J.2
Van Der Kogel, A.3
-
16
-
-
34447503754
-
The potential role of intrinsic hypoxia markers as prognostic variables in cancer
-
Moon E, Brizel D, Chi J, Dewhirst M. The potential role of intrinsic hypoxia markers as prognostic variables in cancer. Antioxid. Redox Signal. 9(8), 1237-1294 (2007).
-
(2007)
Antioxid. Redox Signal.
, vol.9
, Issue.8
, pp. 1237-1294
-
-
Moon, E.1
Brizel, D.2
Chi, J.3
Dewhirst, M.4
-
17
-
-
0025248444
-
NAD(P)H nitroblue tetrazolium reductase levels in apparently normoxic tissues: A histochemical study correlating enzyme activity with binding of radiolabelled misonidazole
-
Cobb LM, Hacker T, Nolan J. NAD(P)H nitroblue tetrazolium reductase levels in apparently normoxic tissues: a histochemical study correlating enzyme activity with binding of radiolabelled misonidazole. Br. J. Cancer 61(4), 524-529 (1990).
-
(1990)
Br. J. Cancer
, vol.61
, Issue.4
, pp. 524-529
-
-
Cobb, L.M.1
Hacker, T.2
Nolan, J.3
-
18
-
-
44349157832
-
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
-
Dewhirst M, Cao Y, Moeller B. Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response. Nat. Rev. Cancer 8(6), 425-437 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, Issue.6
, pp. 425-437
-
-
Dewhirst, M.1
Cao, Y.2
Moeller, B.3
-
19
-
-
67650689649
-
Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia
-
Kizaka-Kondoh S, Konse-Nagasawa H. Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia. Cancer Sci. 100(8), 1366-1373 (2009).
-
(2009)
Cancer Sci.
, vol.100
, Issue.8
, pp. 1366-1373
-
-
Kizaka-Kondoh, S.1
Konse-Nagasawa, H.2
-
20
-
-
84859378451
-
Molecular and cellular pharmacology of the hypoxia-activated prodrug TH?302
-
Meng F, Evans JW, Bhupathi D et al. Molecular and cellular pharmacology of the hypoxia-activated prodrug TH?302. Mol. Cancer Ther. 11(3), 740-751 (2012).
-
(2012)
Mol. Cancer Ther.
, vol.11
, Issue.3
, pp. 740-751
-
-
Meng, F.1
Evans, J.W.2
Bhupathi, D.3
-
21
-
-
84455209531
-
Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck
-
Toustrup K, Sorensen BS, Lassen P, Wiuf C, Alsner J, Overgaard J. Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck. Radiother. Oncol. 102(1), 122-129 (2011).
-
(2011)
Radiother. Oncol.
, vol.102
, Issue.1
, pp. 122-129
-
-
Toustrup, K.1
Sorensen, B.S.2
Lassen, P.3
Wiuf, C.4
Alsner, J.5
Overgaard, J.6
-
22
-
-
80051794223
-
Development of a hypoxia gene expression classifier with predictive impact for hypoxic modification of radiotherapy in head and neck cancer
-
Toustrup K, Sorensen BS, Nordsmark M et al. Development of a hypoxia gene expression classifier with predictive impact for hypoxic modification of radiotherapy in head and neck cancer. Cancer Res. 71(17), 5923-5931 (2011).
-
(2011)
Cancer Res.
, vol.71
, Issue.17
, pp. 5923-5931
-
-
Toustrup, K.1
Sorensen, B.S.2
Nordsmark, M.3
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