Differences in transcriptional effects of 1α,25 dihydroxyvitamin D3 on fibroblasts associated to breast carcinomas and from paired normal breast tissues

Journal of Steroid Biochemistry and Molecular Biology

Volumn 133, Issue 1, 2013, Pages 12-24

  Campos, Laura Tojeiro ^a   Brentani, Helena ^a   Roela, Rosimeire Aparecida ^a   Katayama, Maria Lucia Hirata ^a   Lima, Leandro ^b   Rolim, Cíntia Flores ^c   Milani, Cíntia ^a   Folgueira, Maria Aparecida Azevedo Koike ^a   Brentani, Maria Mitzi ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b A C CAMARGO CANCER CENTER   (Brazil)

^c Instituto Brasileiro de Controle do Cancer   (Brazil)

Author keywords

1 ,25 dihydroxyvitamin D3; Breast carcinoma; Fibroblasts; Gene expression

Indexed keywords

CALCITRIOL; CYTOCHROME P450; VITAMIN D RECEPTOR;

ADULT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CARCINOGENESIS; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DETOXIFICATION; FIBROBLAST; GENE EXPRESSION; GENOMICS; HUMAN; HUMAN CELL; IMMUNOMODULATION; MICROARRAY ANALYSIS; OXIDATIVE STRESS; TRANSCRIPTION REGULATION; UPREGULATION;

ADULT; BREAST; BREAST NEOPLASMS; CALCITRIOL; CARCINOMA, DUCTAL, BREAST; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HUMANS; MIDDLE AGED; TRANSCRIPTOME; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT;

EID: 84867072891     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.08.002     Document Type: Article

References (51)

1. K. Polyak, and R. Kalluri The role of the microenvironment in mammary gland development and cancer Cold Spring Harbor Perspectives in Biology 2 2010 a003244
2. H. Sugimoto, T.M. Mundel, M.W. Kieran, and R. Kalluri Identification of fibroblast heterogeneity in the tumor microenvironment Cancer Biology and Therapy 5 2006 1640 1646
3. R. Kalluri, and M. Zeisberg Fibroblasts in cancer Nature Reviews. Cancer 6 2006 392 401
4. M. Bauer, G. Su, C. Casper, R. He, W. Rehrauer, and A. Friedl Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast Oncogene 29 2010 1732 1740
5. A. Orimo, P.B. Gupta, D.C. Sgroi, F. Arenzana-Seisdedos, T. Delaunay, R. Naeem, V.J. Carey, A.L. Richardson, and R.A. Weinberg Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion Cell 121 2005 335 348
6. P.B. Rozenchan, D.M. Carraro, H. Brentani, L.D. de Carvalho Mota, E.P. Bastos, E.N. e Ferreira, C.H. Torres, M.L. Katayama, R.A. Roela, E.C. Lyra, F.A. Soares, M.A. Folgueira, J.C. Goes, and M.M. Brentani Reciprocal changes in gene expression profiles of cocultured breast epithelial cells and primary fibroblasts International Journal of Cancer 125 2009 2767 2777
7. J. Welsh Vitamin D metabolism in mammary gland and breast cancer Molecular and Cellular Endocrinology 347 2011 55 60
8. D. Matthews, E. LaPorta, G.M. Zinser, C.J. Narvaez, and J. Welsh Genomic vitamin D signaling in breast cancer: insights from animal models and human cells Journal of Steroid Biochemistry and Molecular Biology 121 2010 362 367
9. H. Harant, B. Wolff, and I.J. Lindley 1Alpha,25-dihydroxyvitamin D3 decreases DNA binding of nuclear factor-kappaB in human fibroblasts FEBS Letters 436 1998 329 334
10. F.L. Szeto, J. Sun, J. Kong, Y. Duan, A. Liao, J.L. Madara, and Y.C. Li Involvement of the vitamin D receptor in the regulation of NF-kappaB activity in fibroblasts Journal of Steroid Biochemistry and Molecular Biology 103 2007 563 566
11. J.N. Artaza, F. Sirad, M.G. Ferrini, and K.C. Norris 1,25(OH)2vitamin D3 inhibits cell proliferation by promoting cell cycle arrest without inducing apoptosis and modifies cell morphology of mesenchymal multipotent cells Journal of Steroid Biochemistry and Molecular Biology 119 2010 73 83
12. A.M. Ramirez, C. Wongtrakool, T. Welch, A. Steinmeyer, U. Zugel, and J. Roman Vitamin D inhibition of pro-fibrotic effects of transforming growth factor beta1 in lung fibroblasts and epithelial cells Journal of Steroid Biochemistry and Molecular Biology 118 2010 142 150
13. Y.R. Lou, I. Laaksi, H. Syvala, M. Blauer, T.L. Tammela, T. Ylikomi, and P. Tuohimaa 25-Hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells FASEB Journal 18 2004 332 334
14. A.A. Hidalgo, V.P. Montecinos, R. Paredes, A.S. Godoy, E.M. McNerney, H. Tovar, D. Pantoja, C. Johnson, D. Trump, and S.A. Onate Biochemical characterization of nuclear receptors for vitamin D3 and glucocorticoids in prostate stroma cell microenvironment Biochemical and Biophysical Research Communications 412 2011 13 19
15. D. Pilling, T. Fan, D. Huang, B. Kaul, and R.H. Gomer Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts PLoS One 4 2009 e7475
16. R.D.C. Team R: A Language and Environment for Statistical Computing 2009 R Foundation for Statistical Computing Vienna, Austria
17. T.S. Prasad, K. Kandasamy, and A. Pandey Human Protein Reference Database and Human Proteinpedia as discovery tools for systems biology Methods in Molecular Biology 577 2009 67 79
18. A. Chatr-aryamontri, A. Ceol, L.M. Palazzi, G. Nardelli, M.V. Schneider, L. Castagnoli, and G. Cesareni MINT: the Molecular INTeraction database Nucleic Acids Research 35 2007 D572 D574
19. B. Aranda, P. Achuthan, Y. Alam-Faruque, I. Armean, A. Bridge, C. Derow, M. Feuermann, A.T. Ghanbarian, S. Kerrien, J. Khadake, J. Kerssemakers, C. Leroy, M. Menden, M. Michaut, L. Montecchi-Palazzi, S.N. Neuhauser, S. Orchard, V. Perreau, B. Roechert, K. van Eijk, and H. Hermjakob The IntAct molecular interaction database in 2010 Nucleic Acids Research 38 2010 D525 D531
20. W. Hwang, Y. Cho, A. Zhang, and M. Ramanathan Bridging centrality: identifying bridging nodes in scale-free networks Proceedings of the 12th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining 2006 KDD Philadelphia, PA 20 23
21. S.C. Lebret, D.F. Newgreen, E.W. Thompson, and M.L. Ackland Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors Breast Cancer Research 9 2007 R19
22. A. Sadlonova, D.B. Bowe, Z. Novak, S. Mukherjee, V.E. Duncan, G.P. Page, and A.R. Fros Identification of molecular distinctions between normal breast-associated fibroblasts and breast cancer-associated fibroblasts Cancer Microenvironment 2 2009 9 21
23. D.C. Smith, C.S. Johnson, C.C. Freeman, J. Muindi, J.W. Wilson, and D.L. Trump A Phase I trial of calcitriol (1,25-dihydroxycholecalciferol) in patients with advanced malignancy Clinical Cancer Research 5 1999 1339 1345
24. H. Okuda, A. Kobayashi, B. Xia, M. Watabe, S.K. Pai, S. Hirota, F. Xing, W. Liu, P.R. Pandey, K. Fukuda, V. Modur, A. Ghosh, A. Wilber, and K. Watabe Hyaluronan synthase HAS2 promotes tumor progression in bone by stimulating the interaction of breast cancer stem-like cells with macrophages and stromal cells Cancer Research 72 2012 537 547
25. C. Milani, J. Welsh, M.L. Katayama, E.C. Lyra, M.S. Maciel, M.M. Brentani, and M.A. Folgueira Human breast tumor slices: a model for identification of vitamin D regulated genes in the tumor microenvironment Journal of Steroid Biochemistry and Molecular Biology 121 2010 151 155
26. C. Milani, Efeito da Vitamina D no perfil transcricional de cultura organotípica de câncer de mama, PhD Tesis, Universidade de São Paulo Faculdade de Medicina, 2011. www.teses.usp.br/teses/disponiveis/ 5/5155/tde-19032010-115152/.
27. I.W. Taylor, R. Linding, D. Warde-Farley, Y. Liu, C. Pesquita, D. Faria, S. Bull, T. Pawson, Q. Morris, and J.L. Wrana Dynamic modularity in protein interaction networks predicts breast cancer outcome Nature Biotechnology 27 2009 199 204
28. A.L. Barabasi, and Z.N. Oltvai Network biology: understanding the cell's functional organization Nature Reviews. Genetics 5 2004 101 113
29. K. Townsend, C.M. Banwell, M. Guy, K.W. Colston, J.L. Mansi, P.M. Stewart, M.J. Campbell, and M. Hewison Autocrine metabolism of vitamin D in normal and malignant breast tissue Clinical Cancer Research 11 2005 3579 3586
30. J.C. Montero, R. Rodriguez-Barrueco, A. Ocana, E. Diaz-Rodriguez, A. Esparis-Ogando, and A. Pandiella Neuregulins and cancer Clinical Cancer Research 14 2008 3237 3241
31. L.J. Vuga, A. Ben-Yehudah, E. Kovkarova-Naumovski, T. Oriss, K.F. Gibson, C. Feghali-Bostwick, and N. Kaminski WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis American Journal of Respiratory Cell and Molecular Biology 41 2009 583 589
32. G. Chakravarty, K. Moroz, N.M. Makridakis, S.A. Lloyd, S.E. Galvez, P.R. Canavello, M.R. Lacey, K. Agrawal, and D. Mondal Prognostic significance of cytoplasmic SOX9 in invasive ductal carcinoma and metastatic breast cancer Experimental Biology and Medicine (Maywood, NJ) 236 2011 145 155
33. K. Schror, E. Bretschneider, K. Fischer, J.W. Fischer, R. Pape, B.H. Rauch, A.C. Rosenkranz, and A.A. Weber Thrombin receptors in vascular smooth muscle cells - function and regulation by vasodilatory prostaglandins Thrombosis and Haemostasis 103 2010 884 890
34. X.Q. Tian, T.C. Chen, and M.F. Holick 1,25-Dihydroxyvitamin D3: a novel agent for enhancing wound healing Journal of Cellular Biochemistry 59 1995 53 56
35. N. Erez, M. Truitt, P. Olson, S.T. Arron, and D. Hanahan Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner Cancer Cell 17 2010 135 147
36. Y. Liu, W. Dong, L. Chen, R. Xiang, H. Xiao, G. De, Z. Wang, and Y. Qi BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2 Journal of Biological Chemistry 279 2004 37436 37444
37. X. Peng, A. Vaishnav, G. Murillo, F. Alimirah, K.E. Torres, and R.G. Mehta Protection against cellular stress by 25-hydroxyvitamin D3 in breast epithelial cells Journal of Cellular Biochemistry 110 2010 1324 1333
38. P.L. Kovalenko, Z. Zhang, M. Cui, S.K. Clinton, and J.C. Fleet 1,25 dihydroxyvitamin D-mediated orchestration of anticancer, transcript-level effects in the immortalized, non-transformed prostate epithelial cell line, RWPE1 BMC Genomics 11 2010 26
39. J.L. Costa, P.P. Eijk, M.A. van de Wiel, D. ten Berge, F. Schmitt, C.J. Narvaez, J. Welsh, and B. Ylstra Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down BMC Genomics 10 2009 499
40. K. Suzuki, C. Oneyama, H. Kimura, S. Tajima, and M. Okada Down-regulation of the tumor suppressor C-terminal Src kinase (Csk)-binding protein (Cbp)/PAG1 is mediated by epigenetic histone modifications via the mitogen-activated protein kinase (MAPK)/phosphatidylinositol 3-kinase (PI3K) pathway Journal of Biological Chemistry 286 2011 15698 15706
41. M.D. Vos, A. Martinez, C. Elam, A. Dallol, B.J. Taylor, F. Latif, and G.J. Clark A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stability Cancer Research 64 2004 4244 4250
42. S. Ory, H. Brazier, and A. Blangy Identification of a bipartite focal adhesion localization signal in RhoU/Wrch-1, a Rho family GTPase that regulates cell adhesion and migration Biology of the Cell 99 2007 701 716
43. S. Aust, P. Obrist, M. Klimpfinger, G. Tucek, W. Jager, and T. Thalhammer Altered expression of the hormone- and xenobiotic-metabolizing sulfotransferase enzymes 1A2 and 1C1 in malignant breast tissue International Journal of Oncology 26 2005 1079 1085
44. S. Swami, N. Raghavachari, U.R. Muller, Y.P. Bao, and D. Feldman Vitamin D growth inhibition of breast cancer cells: gene expression patterns assessed by cDNA microarray Breast Cancer Research and Treatment 80 2003 49 62
45. K. Townsend, V. Trevino, F. Falciani, P.M. Stewart, M. Hewison, and M.J. Campbell Identification of VDR-responsive gene signatures in breast cancer cells Oncology 71 2006 111 123
46. H.J. Lee, H. Liu, C. Goodman, Y. Ji, H. Maehr, M. Uskokovic, D. Notterman, M. Reiss, and N. Suh Gene expression profiling changes induced by a novel Gemini Vitamin D derivative during the progression of breast cancer Biochemical Pharmacology 72 2006 332 343
47. B. Byrne, and J. Welsh Identification of novel mediators of Vitamin D signaling and 1,25(OH)2D3 resistance in mammary cells Journal of Steroid Biochemistry and Molecular Biology 103 2007 703 707
48. K. Strumane, A. Bonnomet, C. Stove, R. Vandenbroucke, B. Nawrocki-Raby, E. Bruyneel, M. Mareel, P. Birembaut, G. Berx, and F. van Roy E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion Cancer Research 66 2006 10007 10015
49. D.W. Kang, M.H. Park, Y.J. Lee, H.S. Kim, C.W. Lindsley, H. Alex Brown, and S. Min do Autoregulation of phospholipase D activity is coupled to selective induction of phospholipase D1 expression to promote invasion of breast cancer cells International Journal of Cancer 128 2011 805 816
50. J.J. Cai, E. Borenstein, and D.A. Petrov Broker genes in human disease Genome Biology and Evolution 2 2010 815 825
51. A. Risco, and A. Cuenda New insights into the p38γ and p38δ MAPK pathways Journal of Signal Transduction 2012 2012 520289