Presence, localization, and origin of clusterin in normal human spermatozoa

Journal of Assisted Reproduction and Genetics

Volumn 29, Issue 8, 2012, Pages 751-757

  Han, Zhijian ^a   Wang, Zengjun ^a   Cheng, Gong ^a   Liu, Bianjiang ^a   Li, Pengchao ^a   Li, Jie ^a   Wang, Wei ^a   Yin, Changjun ^a   Zhang, Wei ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Clusterin; Human; Spermatozoa; Testis

Indexed keywords

CLUSTERIN;

ADULT; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; HUMAN; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SPERMATOZOON; TESTIS; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL MEMBRANE; CLUSTERIN; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MALE; SERTOLI CELLS; SPERM MOTILITY; SPERMATOGENESIS; SPERMATOZOA; TESTIS;

MAMMALIA;

EID: 84867064418     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-012-9779-x     Document Type: Article

References (43)

1. Ahuja HS, Tenniswood M, Zakeri ZF. Differential expression of clusterin in the testis and epididymis of postnatal and germ cell deficient mice. J Androl. 1996;17:491-501.
2. Atlas-White M, Murphy BF, Baker HW. Localisation of clusterin in normal human sperm by immunogold electron microscopy. Pathology. 2000;32:258-61.
3. Bailey R, Griswold MD. Clusterin in the male reproductive system: localization and possible function. Mol Cell Endocrinol. 1999;151:17-23.
4. Bettuzzi S, Rizzi F. Nuclear CLU (nCLU) and the fate of the cell. Adv Cancer Res. 2009;104:59-88.
5. Blaschuk O, Burdzy K, Fritz IB. Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid. J Biol Chem. 1983;258:7714-20.
6. Calero M, Rostagno A, Frangione B, et al. Clusterin and Alzheimer's disease. Subcell Biochem. 2005;38:273-98.
7. Carlsson L, Ronquist G, Nilsson BO, et al. Dominant prostasome immunogens for sperm-agglutinating autoantibodies of infertile men. J Androl. 2004;25:699-705.
8. Griffiths GS, Galileo DS, Aravindan RG, et al. Clusterin facilitates exchange of glycosyl phosphatidylinositol-linked SPAM1 between reproductive luminal fluids and mouse and human sperm membranes. Biol Reprod. 2009;81:562-70.
9. Hermo L, Wright J, Oko R, et al. Role of epithelial cells of the male excurrent duct system of the rat in the endocytosis or secretion of sulfated glycoprotein-2 (clusterin). Biol Reprod. 1991;44:1113-31.
10. Hidaka S, Kranzlin B, Gretz N, et al. Urinary clusterin levels in the rat correlate with the severity of tubular damage and may help to differentiate between glomerular and tubular injuries. Cell Tissue Res. 2002;310:289-96.
11. Humphreys DT, Carver JA, Easterbrook-Smith SB, et al. Clusterin has chaperone-like activity similar to that of small heat shock proteins. J Biol Chem. 1999;274:6875-81.
12. Ibrahim NM, Gilbert GR, Loseth KJ, et al. Correlation between clusterin-positive spermatozoa determined by flow cytometry in bull semen and fertility. J Androl. 2000;21:887-94.
13. Ibrahim NM, Foster DN, Crabo BG. Localization of clusterin on freeze-preserved bull spermatozoa before and after glass woolsephadex filtration. J Androl. 2001;22:891-902.
14. Ibrahim NM, Romano JE, Troedsson MH, et al. Effect of scrotal insulation on clusterin-positive cells in ram semen and their relationship to semen quality. J Androl. 2001;22:863-77.
15. Jenne DE, Lowin B, Peitsch MC, et al. Clusterin (complement lysis inhibitor) forms a high density lipoprotein complex with apolipoprotein A-I in human plasma. J Biol Chem. 1991;266:11030-6.
16. Lambard S, Galeraud-Denis I, Martin G, et al. Analysis and significance of mRNA in human ejaculated sperm from normozoospermic donors: relationship to sperm motility and capacitation. Mol Hum Reprod. 2004;10:535-41.
17. Lambard S, Galeraud-Denis I, Saunders PT, et al. Human immature germ cells and ejaculated spermatozoa contain aromatase and oestrogen receptors. J Mol Endocrinol. 2004;32:279-89.
18. Leskov KS, Klokov DY, Li J, et al. Synthesis and functional analyses of nuclear clusterin, a cell death protein. J Biol Chem. 2003;278:11590-600.
19. Liu B, Wang P, Wang Z, et al. Analysis and difference of voltage-dependent anion channel mRNA in ejaculated spermatozoa from normozoospermic fertile donors and infertile patients with idiopathic asthenozoospermia. J Assist Reprod Genet. 2010;27:719-24.
20. Martínez-Heredia J, de Mateo S, Vidal-Taboada JM, et al. Identification of proteomic differences in asthenozoospermic sperm samples. Hum Reprod. 2008;23:783-91.
21. McCann CT, Chantler E. Properties of sperm separated using Percoll and IxaPrep density gradients. A comparison made using CASA, longevity, morphology and the acrosome reaction. Int J Androl. 2000;23:205-9.
22. Miller KF, Falcone T, Goldberg JM. Variation in recovery of motile sperm after preparation by a simple Percoll gradient technique. J Assist Reprod Genet. 1996;13:485-8.
23. Murphy BF, Kirszbaum L, Walker ID, et al. SP-40,40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis. J Clin Invest. 1988;81:1858-64.
24. O'Bryan MK, Baker HW, Saunders JR, et al. Human seminal clusterin (SP-40,40). Isolation and characterization. J Clin Invest. 1990;85:1477-86.
25. O'Bryan MK, Mallidis C, Murphy BF, et al. Immunohistological localization of clusterin in the male genital tract in humans and marmosets. Biol Reprod. 1994;50:502-9.
26. O'Bryan MK, Murphy BF, Liu DY, et al. The use of anticlusterin monoclonal antibodies for the combined assessment of human sperm morphology and acrosome integrity. Hum Reprod. 1994;9:1490-6.
27. Pucci S, Bonanno E, Pichiorri F, et al. Modulation of different clusterin isoforms in human colon tumorigenesis. Oncogene. 2004;23:2298-304.
28. Reddy KB, Jin G, Karode MC, et al. Transforming growth factor beta (TGF beta)-induced nuclear localization of apolipoprotein J/clusterin in epithelial cells. Biochemistry. 1996;35:6157-63.
29. Reyes-Moreno C, Boilard M, Sullivan R, et al. Characterization and identification of epididymal factors that protect ejaculated bovine sperm during in vitro storage. Biol Reprod. 2002;66:159-66.
30. Silkensen JR, Skubitz KM, Skubitz AP, et al. Clusterin promotes the aggregation and adhesion of renal porcine epithelial cells. J Clin Invest. 1995;96:2646-53.
31. Silkensen JR, Skubitz AP, Skubitz KM, et al. Identification of clusterin sequences mediating renal tubular cell interactions. J Pept Res. 1999;54:449-57.
32. Sylvester SR, Morales C, Oko R, et al. Localization of sulfated glycoprotein-2 (clusterin) on spermatozoa and in the reproductive tract of the male rat. Biol Reprod. 1991;45:195-207.
33. Sylvester SR, Skinner MK, Griswold MD. A sulfated glycoprotein synthesized by Sertoli cells and by epididymal cells is a component of the sperm membrane. Biol Reprod. 1984;31: 1087-101.
34. Tenniswood MP, Guenette RS, Lakins J, et al. Active cell death in hormone-dependent tissues. Cancer Metastasis Rev. 1992;11:197-220.
35. Thacker S, Yadav SP, Sharma RK, et al. Evaluation of sperm proteins in infertile men: a proteomic approach. Fertil Steril. 2011;95:2745-8.
36. Trougakos IP, Gonos ES. Clusterin/apolipoprotein J in human aging and cancer. Int J Biochem Cell Biol. 2002;34:1430-48.
37. Trougakos IP, Poulakou M, Stathatos M, et al. Serum levels of the senescence biomarker clusterin/apolipoprotein J increase significantly in diabetes type II and during development of coronary heart disease or at myocardial infarction. Exp Gerontol. 2002;37:1175-87.
38. Tung PS, Fritz IB. Immunolocalization of clusterin in the ram testis, rete testis, and excurrent ducts. Biol Reprod. 1985;33:177-86.
39. Wang Z, Widgren EE, Richardson RT, et al. Characterization of an eppin protein complex from human semen and spermatozoa. Biol Reprod. 2007;77:476-84.
40. Wehrli P, Charnay Y, Vallet P, et al. Inhibition of post-ischemic brain injury by clusterin overexpression. Nat Med. 2001;7:977-9.
41. Wong P, Pineault J, Lakins J, et al. Genomic organization and expression of the rat TRPM-2 (clusterin) gene, a gene implicated in apoptosis. J Biol Chem. 1993;268:5021-31.
42. Yang CR, Yeh S, Leskov K, et al. Isolation of Ku70-binding proteins (KUBs). Nucleic Acids Res. 1999;27:2165-74.
43. Yang CR, Leskov K, Hosley-Eberlein K, et al. Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death. Proc Natl Acad Sci U S A. 2000;97:5907-12.