Translocating the blood-brain barrier using electrostatics

Frontiers in Cellular Neuroscience

Volumn , Issue SEPTEMBER, 2012, Pages 1-14

  Ribeiro, Marta M B ^a   Domingues, Marco M ^a   Freire, João M ^a   Santos, Nuno C ^a   Castanho, Miguel A R B ^a  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

Author keywords

Blood Cells; Blood Brain Barrier; Cell surface charge; Drug Targeting; Zeta potential

Indexed keywords

ADULT; ANION TRANSPORT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CELL STRUCTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ERYTHROCYTE; HOMEOSTASIS; HUMAN; HUMAN CELL; LIGHT SCATTERING; LIPOPHILICITY; PERIPHERAL BLOOD MONONUCLEAR CELL; STATIC ELECTRICITY; SURFACE CHARGE; THROMBOCYTE; UMBILICAL VEIN ENDOTHELIAL CELL; ZETA POTENTIAL;

EID: 84867062087     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2012.00044     Document Type: Article

References (32)

1. Adak S, Chowdhury S, Bhattacharyya M (2008). Dynamic and electrokinetic behavior of erythrocyte membrane in diabetes mellitus and diabetic cardiovascular disease. Biochim Biophys Acta 1780(2): 108-115.
2. Anderson J (1981). Concentration dependence of electrophoretic mobility. Journal of Colloid and Interface Science (1): 248-250.
3. Buser CA, Sigal CT, Resh MD, McLaughlin S (1994). Membrane binding of myristylated peptides corresponding to the NH2 terminus of Src. Biochemistry 33(44): 13093-13101.
4. Cansell M, Gouygou JP, Jozefonvicz J, Letourneur D (1997). Lipid composition of cultured endothelial cells in relation to their growth. Lipids 32(1): 39-44.
5. Carvalho FA, de Oliveira S, Freitas T, Goncalves S, Santos NC (2010). Variations on fibrinogenerythrocyte interactions during cell aging. PLoS One 6(3): e18167.
6. Castanho M, Santos N, Loura L (1997). Separating the turbidity spectra of vesicles from the absorption spectra of membrane probes and other chromophores. Eur Biophys J 26: 253-259.
7. Chen X, Huang Y, Liu W, Yuan Z (2007). Membrane surface charge and morphological and mechanical properties of young and old erythrocytes. Current Applied Physics 7: 94-96.
8. Daleke DL (2008). Regulation of phospholipid asymmetry in the erythrocyte membrane. Curr Opin Hematol 15(3): 191-195.
9. Delgado AV, González-Caballero F, Hunter RJ, Koopal LK, J L (2005). Measurement and interpretation of electrokinetic phenomena. Pure and Applied Chemistry 77: 1753-1805.
10. Domingues MM, Santiago PS, Castanho MA, Santos NC (2008). What can light scattering spectroscopy do for membrane-active peptide studies? J Pept Sci 14(4): 394-400.
11. dos Santos WL, Rahman J, Klein N, Male DK (1995). Distribution and analysis of surface charge on brain endothelium in vitro and in situ. Acta Neuropathol 90(3): 305-311.
12. Elul R (1967). Fixed charge in the cell membrane. J Physiol 189(3): 351-365.
13. Eylar EH, Madoff MA, Brody OV, Oncley JL (1962). The contribution of sialic acid to the surface charge of the erythrocyte. J Biol Chem 237: 1992-2000.
14. Garberg P, Ball M, Borg N, Cecchelli R, Fenart L, Hurst RD, et al. (2005). In vitro models for the blood-brain barrier. Toxicol In Vitro 19(3): 299-334.
15. Goldenberg NM, Steinberg BE (2010). Surface charge: a key determinant of protein localization and function. Cancer Res 70(4): 1277-1280.
16. Gumbleton M, Audus KL (2001). Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier. J Pharm Sci 90(11): 1681-1698.
17. Henriques ST, Melo MN, Castanho MA (2006). Cell-penetrating peptides and antimicrobial peptides: how different are they? Biochem J 399(1): 1-7.
18. Kaszuba M, Corbett J, Watson FM, Jones A (2010). High-concentration zeta potential measurements using light-scattering techniques. Philos Transact A Math Phys Eng Sci 368(1927): 4439-4451.
19. Klein NJ, Shennan GI, Heyderman RS, Levin M (1992). Alteration in glycosaminoglycan metabolism and surface charge on human umbilical vein endothelial cells induced by cytokines, endotoxin and neutrophils. J Cell Sci 102 (Pt 4): 821-832.
20. Kuliszkiewicz-Janus M, Tuz MA, Baczynski S, Prajs I, Jazwiec B (2005). 31P MRS analysis of the phospholipid composition of normal human peripheral blood mononuclear cells (PBMC). Cell Mol Biol Lett 10(3): 373-382.
21. Male D, Pryce G, Rahman J (1990). Comparison of the immunological properties of rat cerebral and aortic endothelium. J Neuroimmunol 30(2-3): 161-168.
22. Mayer LD, Hope MJ, Cullis PR (1986). Vesicles of variable sizes produced by a rapid extrusion procedure. Biochim Biophys Acta 858(1): 161-168.
23. Owen JS, Hutton RA, Day RC, Bruckdorfer KR, McIntyre N (1981). Platelet lipid composition and platelet aggregation in human liver disease. J Lipid Res 22(3): 423-430.
24. Pryce G, Santos W, Male D (1994). An assay for the analysis of lymphocyte migration across cerebral endothelium in vitro. J Immunol Methods 167(1-2): 55-63.
25. Ribeiro MM, Melo MN, Serrano ID, Santos NC, Castanho MA (2010). Drug-lipid interaction evaluation: why a 19th century solution? Trends Pharmacol Sci 31(10): 449-454.
26. Ribeiro MM, Pinto AR, Domingues MM, Serrano I, Heras M, Bardaji ER, et al. (2011). Chemical conjugation of the neuropeptide kyotorphin and Ibuprofen enhances brain targeting and analgesia. Mol Pharm 8(5): 1929-1940.
27. Tamai I, Sai Y, Kobayashi H, Kamata M, Wakamiya T, Tsuji A (1997). Structure-internalization relationship for adsorptive-mediated endocytosis of basic peptides at the blood-brain barrier. J Pharmacol Exp Ther 280(1): 410-415.
28. Tatsumi N, Tsuda I, Masaoka M, Imai K (1992). Measurement of the zeta potential of human platelets by the use of laser-light scattering. Thromb Res 65(4-5): 585-592.
29. Tewes BJ, Galla HJ (2001). Lipid polarity in brain capillary endothelial cells. Endothelium 8(3): 207-220.
30. Yeung T, Gilbert GE, Shi J, Silvius J, Kapus A, Grinstein S (2008). Membrane phosphatidylserine regulates surface charge and protein localization. Science 319(5860): 210-213.
31. Yeung T, Heit B, Dubuisson JF, Fairn GD, Chiu B, Inman R, et al. (2009). Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. J Cell Biol 185(5): 917-928.
32. Zwaal RF, Comfurius P, Bevers EM (2005). Surface exposure of phosphatidylserine in pathological cells. Cell Mol Life Sci 62(9): 971-988.