Modification of a previously published HPLC-UV method for metformin determination, validation and application to test bioequivalence

Jordan Journal of Pharmaceutical Sciences

Volumn 5, Issue 2, 2012, Pages 87-100

  Al Nimry, Suhair ^a   Tamimi, Jaafar Al ^b   Zaid, Yousef ^b   AlKhatib, Khaleda ^b   Khalil, Claude ^c   Akl, Marleine ^c  

^a JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Jordan)

^b Arab Company for Drug Industries & Medical Appliances   (Jordan)

^c Algorithm Pharmaceutical Manufacturers SAL   (Lebanon)

Author keywords

Bioequivalence; HPLC UV; Human plasma; Metformin; Protein precipitation

Indexed keywords

ACETONITRILE; ATENOLOL; DICHLOROMETHANE; GLYSTOR; HYDROCHLORIC ACID; METFORMIN; PHOSPHATE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; CALIBRATION; CONCENTRATION (PARAMETERS); DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSAGE FORM COMPARISON; DRUG HALF LIFE; DRUG STABILITY; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIMIT OF QUANTITATION; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PH; PRECIPITATION; QUALITY CONTROL; ROOM TEMPERATURE; SINGLE DRUG DOSE; STATISTICAL ANALYSIS; STORAGE TEMPERATURE; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRAVIOLET SPECTROSCOPY; VOLUNTEER;

EID: 84867021689     PISSN: 19957157     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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