메뉴 건너뛰기




Volumn 32, Issue 9, 2012, Pages 3861-3868

Cancer immunotherapy by intratumoral injection of α-gal glycolipids

Author keywords

gal glycolipids; Anti Gal antibody; Autologous tumor antigens; Cancer immunotherapy

Indexed keywords

ALPHA GAL GLYCOLIPID; ALPHA GAL GLYCOLIPID ANTIBODY; ANTIBODY; ANTINEOPLASTIC AGENT; CANCER VACCINE; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 84867009699     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (26)

References (31)
  • 4
    • 33947216118 scopus 로고    scopus 로고
    • The adaptive immunologic microenvironment in colorectal cancer: A novel perspective
    • DOI 10.1158/0008-5472.CAN-06-4806
    • Galon J, Fridman WH and Pagès F: The adaptive immunologic microenvironment in colorectal cancer: a novel perspective. Cancer Res 67: 1883-1886, 2007. (Pubitemid 46424201)
    • (2007) Cancer Research , vol.67 , Issue.5 , pp. 1883-1886
    • Galon, J.1    Fridman, W.-H.2    Pages, F.3
  • 7
    • 0036852191 scopus 로고    scopus 로고
    • Natural selection of tumor variants in the generation of "tumor escape" phenotypes
    • DOI 10.1038/ni1102-999
    • Khong HT and Restifo NP: Natural selection of tumor variants in the generation of "tumor escape" phenotypes. Nat Immunol 3: 999-1005, 2002. (Pubitemid 35363649)
    • (2002) Nature Immunology , vol.3 , Issue.11 , pp. 999-1005
    • Khong, H.T.1    Restifo, N.P.2
  • 10
    • 0030272224 scopus 로고    scopus 로고
    • Unique tumor antigens redefined as mutant tumor-specific antigens
    • DOI 10.1006/smim.1996.0037
    • Mumberg D, Wick M and Schreiber H: Unique tumor antigens redefined as mutant tumor-specific antigens. Semin Immunol 8: 289-293, 1996. (Pubitemid 26413869)
    • (1996) Seminars in Immunology , vol.8 , Issue.5 , pp. 289-293
    • Mumberg, D.1    Wick, M.2    Schreiber, H.3
  • 11
    • 5644293181 scopus 로고    scopus 로고
    • Autologous tumor vaccines processed to express α-gal epitopes: A practical approach to immunotherapy in cancer
    • Galili U: Autologous tumor vaccines processed to express α-gal epitopes: A practical approach to immunotherapy in cancer. Cancer Immunol Immunother 53: 935-945, 2004.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 935-945
    • Galili, U.1
  • 12
    • 0029076718 scopus 로고
    • Primaring of tumor-specific T cells in the draining lymph nodes after immunization with interleukin-2 secreting tumor cells: Three consecutive stages may be required for successful tumor vaccination
    • Schmidt W, Schweighoffer T, Herbst E, Maass G, Berger M, Schilcher F, Schaffner G and Birnstiel ML: Primaring of tumor-specific T cells in the draining lymph nodes after immunization with interleukin-2 secreting tumor cells: Three consecutive stages may be required for successful tumor vaccination. Proc Natl Acad Sci USA 92: 5540-5544, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5540-5544
    • Schmidt, W.1    Schweighoffer, T.2    Herbst, E.3    Maass, G.4    Berger, M.5    Schilcher, F.6    Schaffner, G.7    Birnstiel, M.L.8
  • 13
    • 0030975532 scopus 로고    scopus 로고
    • Antigen localization regulates immune responses in a dose and time dependent fashion: A geographical view of immune reactivity
    • Zinkernagel RM, Ehl S, Aichele P, Oehen S, Kündig T and Hengartner H: Antigen localization regulates immune responses in a dose and time dependent fashion: A geographical view of immune reactivity. Immunol Rev 156: 199-211, 1997.
    • (1997) Immunol Rev , vol.156 , pp. 199-211
    • Zinkernagel, R.M.1    Ehl, S.2    Aichele, P.3    Oehen, S.4    Kündig, T.5    Hengartner, H.6
  • 14
    • 45549092607 scopus 로고    scopus 로고
    • Cancer Immunology
    • Finn OJ: Cancer Immunology. New Engl J Med 358: 2704-2015, 2008.
    • (2008) New Engl J Med , vol.358 , pp. 2704-12015
    • Finn, O.J.1
  • 15
    • 0035320526 scopus 로고    scopus 로고
    • A fresh look at tumor immunosurveillance and immunotherapy
    • DOI 10.1038/86297
    • Smyth MJ, Godfrey DI and Trapani JA: A fresh look at tumor immunosurveillance and immunotherapy. Nat Immunol 2: 293-299, 2001. (Pubitemid 33706339)
    • (2001) Nature Immunology , vol.2 , Issue.4 , pp. 293-299
    • Smyth, M.J.1    Godfrey, D.I.2    Trapani, J.A.3
  • 16
    • 20344396137 scopus 로고    scopus 로고
    • Anti-Gal-mediated targeting of human B lymphoma cells to antigen-presenting cells: A potential method for immunotherapy using autologous tumor cells
    • Manches O, Plumas J, Lui G, Chaperot L, Molens JP, Sotto JJ, Bensa JC and Galili U: Anti-Gal mediated targeting of human B lymphoma cells to antigen-presenting cells: a potential method for immunotherapy with autologous tumor cells. Haematologica 90: 625-634, 2005. (Pubitemid 40780881)
    • (2005) Haematologica , vol.90 , Issue.5 , pp. 625-634
    • Manches, O.1    Plumas, J.2    Lui, G.3    Chaperot, L.4    Molens, J.-P.5    Sotto, J.-J.6    Bensa, J.-C.7    Galili, U.8
  • 17
    • 33947682719 scopus 로고    scopus 로고
    • Intratumoral injection of alpha-gal glycolipids induces xenograft-like destruction and conversion of lesions into endogenous vaccines
    • Galili U, Wigglesworth K and Abdel-Motal UM: Intratumoral injection α-gal glycolipids induces xenograft-like destruction and conversion of lesions into endogenous vaccines. J Immunol 178: 4676-4687, 2007. (Pubitemid 46501667)
    • (2007) Journal of Immunology , vol.178 , Issue.7 , pp. 4676-4687
    • Galili, U.1    Wigglesworth, K.2    Abdel-Motal, U.M.3
  • 18
    • 68549140182 scopus 로고    scopus 로고
    • Intratumoral injection α-gal glycolipids induces a protective anti-tumor T cell response which overcomes Treg activity
    • Abdel-Motal UM, Wigglesworth K and Galili U: Intratumoral injection α-gal glycolipids induces a protective anti-tumor T cell response which overcomes Treg activity. Cancer Immunol Immunother 58: 1545-1556, 2009.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1545-1556
    • Abdel-Motal, U.M.1    Wigglesworth, K.2    Galili, U.3
  • 19
    • 0021678856 scopus 로고
    • A unique natural human IgG antibody with anti-alpha-galactosyl specificity
    • DOI 10.1084/jem.160.5.1519
    • Galili U, Rachmilewitz EA, Peleg A and Flechner I: A unique natural human IgG antibody with antα-galactosyl specificity. J Exp Med 160: 1519-1531, 1984. (Pubitemid 15220780)
    • (1984) Journal of Experimental Medicine , vol.160 , Issue.5 , pp. 1519-1531
    • Galili, U.1    Rachmilewitz, E.A.2    Peleg, A.3    Flechner, I.4
  • 20
    • 0022260876 scopus 로고
    • Human natural anti-alpha-galactosyl IgG. II. The specific recognition of alpha(1,3)-linked galactose residues
    • DOI 10.1084/jem.162.2.573
    • Galili U, Macher BA, Buehler JS and Shohet SB: Human natural anti-α-galactosyl IgG. II. The specific recognition α (1,3)-linked galactose residues. J Exp Med 16: 573-582, 1985. (Pubitemid 15249960)
    • (1985) Journal of Experimental Medicine , vol.162 , Issue.2 , pp. 573-582
    • Galili, U.1    Macher, B.A.2    Buehler, J.3    Shohet, S.B.4
  • 22
    • 0024297335 scopus 로고
    • Man, apes, and Old World monkeys differ from other mammals in the expression α-galactosyl epitopes on nucleated cells
    • Galili U, Shohet SB, Kobrin E, Stults CL and Macher BA: Man, apes, and Old World monkeys differ from other mammals in the expression α-galactosyl epitopes on nucleated cells. J Biol Chem 263: 17755-17762, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 17755-17762
    • Galili, U.1    Shohet, S.B.2    Kobrin, E.3    Stults, C.L.4    Macher, B.A.5
  • 23
    • 38749117878 scopus 로고    scopus 로고
    • The Galα,3Galß1,4GlcNAc-R (α-Gal) epitope: A carbohydrate of unique evolution and clinical relevance
    • Macher BA and Galili U: The Galα,3Galß1,4GlcNAc-R (α-Gal) epitope: a carbohydrate of unique evolution and clinical relevance. Biochem Biophys Acta 1780: 75-88, 2008.
    • (2008) Biochem Biophys Acta , vol.1780 , pp. 75-88
    • Macher, B.A.1    Galili, U.2
  • 24
    • 0027508081 scopus 로고
    • Interaction of the natural anti-Gal antibody wit α-galactosyl epitopes: A major obstacle for xenotranplantation in humans
    • Galili U: Interaction of the natural anti-Gal antibody wit α-galactosyl epitopes: a major obstacle for xenotranplantation in humans. Immunol Today 14: 480-482, 1993.
    • (1993) Immunol Today , vol.14 , pp. 480-482
    • Galili, U.1
  • 27
    • 0029039406 scopus 로고
    • Cardiac xenografts between primate species provide evidence of the α-galactosyl determinant in hyperacute rejection
    • Collins BH, Cotterell HA, McCurry KR, Alvarado CG, Magee JC, Parker W and Platt JL: Cardiac xenografts between primate species provide evidence of the α-galactosyl determinant in hyperacute rejection. J Immunol 154: 5500-5510, 1995.
    • (1995) J Immunol , vol.154 , pp. 5500-5510
    • Collins, B.H.1    Cotterell, H.A.2    McCurry, K.R.3    Alvarado, C.G.4    Magee, J.C.5    Parker, W.6    Platt, J.L.7
  • 28
    • 0032571848 scopus 로고    scopus 로고
    • A sensitive assay for measuring alpha-Gal epitope expression on cells by a monoclonal anti-Gal antibody
    • DOI 10.1097/00007890-199804270-00020
    • Galili U, LaTemple DC and Radic MZ: A sensitive assay for measurin α-gal epitope expression on cells by a monoclonal anti-Gal antibody. Transplantation 65: 1129-1132, 1998. (Pubitemid 28208434)
    • (1998) Transplantation , vol.65 , Issue.8 , pp. 1129-1132
    • Galili, U.1    Latemple, D.C.2    Radic, M.Z.3
  • 29
    • 33846620083 scopus 로고    scopus 로고
    • Replacement of human anterior cruciate ligaments with pig ligaments: A model for anti-non-gal antibody response in long-term xenotransplantation
    • DOI 10.1097/01.tp.0000250598.29377.13, PII 0000789020070127000012
    • Stone KR, Abdel-Motal U, Walgenbach AW, Turek TJ and Galili U: Replacement of human anterior cruciate ligament with pig ligament: a model for anti-non gal antibody response in long-term xenotransplantation. Transplantation 83: 211-219, 2007. (Pubitemid 46185212)
    • (2007) Transplantation , vol.83 , Issue.2 , pp. 211-219
    • Stone, K.R.1    Abdel-Motal, U.M.2    Walgenbach, A.W.3    Turek, T.J.4    Galili, U.5
  • 30
    • 78449243490 scopus 로고    scopus 로고
    • Anti-CTLA-4 antibody therapy: Immune monitoring during clinical development of a novel immunotherapy
    • Callahan MK, Wolchok JD and Allison JP: Anti-CTLA-4 antibody therapy: Immune monitoring during clinical development of a novel immunotherapy. Semin Oncol 37: 473-484, 2010.
    • (2010) Semin Oncol , vol.37 , pp. 473-484
    • Callahan, M.K.1    Wolchok, J.D.2    Allison, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.