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Volumn 7, Issue 9, 2012, Pages

Sodium Bicarbonate Treatment during Transient or Sustained Lactic Acidemia in Normoxic and Normotensive Rats

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTOKINASE; BICARBONATE; CHLORIDE; GLUCOSE; HEMOGLOBIN; LACTIC ACID;

EID: 84867004396     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046035     Document Type: Article
Times cited : (13)

References (50)
  • 1
    • 0001460268 scopus 로고
    • Excess lactate: an index of reversibility in human patients
    • Broder G, Weil M, (1964) Excess lactate: an index of reversibility in human patients. Science 143 (3613):: 1457-1459.
    • (1964) Science , vol.143 , Issue.3613 , pp. 1457-1459
    • Broder, G.1    Weil, M.2
  • 2
    • 0014794257 scopus 로고
    • Experimental and clinical studies on lactate and pyruvate as indicators of the severity of acute circulatory failure (shock
    • Weil M, Afifi A, (1970) Experimental and clinical studies on lactate and pyruvate as indicators of the severity of acute circulatory failure (shock). Circulation 41 (6):: 989-1001.
    • (1970) Circulation , vol.41 , Issue.6 , pp. 989-1001
    • Weil, M.1    Afifi, A.2
  • 3
    • 0015009167 scopus 로고
    • Blood lactate in the prognosis of various forms of shock
    • Vitek V, Cowley RA, (1971) Blood lactate in the prognosis of various forms of shock. Ann Surg 173 (2):: 308-313.
    • (1971) Ann Surg , vol.173 , Issue.2 , pp. 308-313
    • Vitek, V.1    Cowley, R.A.2
  • 4
    • 0015603395 scopus 로고
    • Quantitation of severity of critical illness with special reference to blood lactate
    • Cady LD, Weil MH, Afifi A, Michaels SF, Liu VY, et al. (1973) Quantitation of severity of critical illness with special reference to blood lactate. Crit Care Med 1 (2):: 75-80.
    • (1973) Crit Care Med , vol.1 , Issue.2 , pp. 75-80
    • Cady, L.D.1    Weil, M.H.2    Afifi, A.3    Michaels, S.F.4    Liu, V.Y.5
  • 5
    • 0025735897 scopus 로고
    • Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock
    • Bakker J, Coffernils M, Leon M, Gris P, Vincent JL, (1991) Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock. Chest 99 (4):: 956-962.
    • (1991) Chest , vol.99 , Issue.4 , pp. 956-962
    • Bakker, J.1    Coffernils, M.2    Leon, M.3    Gris, P.4    Vincent, J.L.5
  • 6
    • 33750305320 scopus 로고    scopus 로고
    • Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients
    • Gunnerson KJ, Saul M, He S, Kellum JA, (2006) Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients. Crit Care 10 (1):: R22.
    • (2006) Crit Care , vol.10 , Issue.1
    • Gunnerson, K.J.1    Saul, M.2    He, S.3    Kellum, J.A.4
  • 7
    • 58649098774 scopus 로고    scopus 로고
    • The prognostic value of blood lactate levels relative to that of vital signs in the pre-hospital setting: a pilot study
    • Jansen TC, van Bommel J, Mulder PG, Rommes JH, Schieveld SJM, et al. (2008) The prognostic value of blood lactate levels relative to that of vital signs in the pre-hospital setting: a pilot study. Crit Care 12 (6):: R160.
    • (2008) Crit Care , vol.12 , Issue.6
    • Jansen, T.C.1    van Bommel, J.2    Mulder, P.G.3    Rommes, J.H.4    Schieveld, S.J.M.5
  • 9
    • 77953000739 scopus 로고    scopus 로고
    • Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study
    • Nichol AD, Egi M, Pettila V, Bellomo R, French C, et al. (2010) Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study. Crit Care 14 (1):: R25.
    • (2010) Crit Care , vol.14 , Issue.1
    • Nichol, A.D.1    Egi, M.2    Pettila, V.3    Bellomo, R.4    French, C.5
  • 10
    • 0033976601 scopus 로고    scopus 로고
    • Sodium bicarbonate for the treatment of lactic acidosis
    • Forsythe SM, Schmidt GA, (2000) Sodium bicarbonate for the treatment of lactic acidosis. Chest 117 (1):: 260-267.
    • (2000) Chest , vol.117 , Issue.1 , pp. 260-267
    • Forsythe, S.M.1    Schmidt, G.A.2
  • 11
    • 77950937978 scopus 로고    scopus 로고
    • Treatment of lactic acidosis: appropriate confusion
    • Rachoin JS, Weisberg, McFadden CB, (2010) Treatment of lactic acidosis: appropriate confusion. J Hosp Med 5 (4):: E1-E7.
    • (2010) J Hosp Med , vol.5 , Issue.4
    • Rachoin, J.S.1    Weisberg2    McFadden, C.B.3
  • 12
    • 0029793405 scopus 로고    scopus 로고
    • Current concepts in acid-base balance: use of bicarbonate in patients with metabolic acidosis
    • Arieff AI, (1996) Current concepts in acid-base balance: use of bicarbonate in patients with metabolic acidosis. Current Anaesthesia & Critical Care 7: 182-186.
    • (1996) Current Anaesthesia & Critical Care , vol.7 , pp. 182-186
    • Arieff, A.I.1
  • 13
    • 0025934559 scopus 로고
    • Effects of bicarbonate therapy on hemodynamics and tissue oxygenation in patients with lactic-acidosis: a prospective, controlled clinical study
    • Mathieu D, Neviere R, Billard V, Fleyfel M, Wattel F, (1991) Effects of bicarbonate therapy on hemodynamics and tissue oxygenation in patients with lactic-acidosis: a prospective, controlled clinical study. Crit Care Med 19 (11):: 1352-1356.
    • (1991) Crit Care Med , vol.19 , Issue.11 , pp. 1352-1356
    • Mathieu, D.1    Neviere, R.2    Billard, V.3    Fleyfel, M.4    Wattel, F.5
  • 14
    • 0025265865 scopus 로고
    • Bicarbonate does not improve hemodynamics in critically ill patients who have lactic acidosis. A prospective, controlled clinical study
    • Cooper DJ, Walley KR, Wiggs BR, Russell JA, (1990) Bicarbonate does not improve hemodynamics in critically ill patients who have lactic acidosis. A prospective, controlled clinical study. Ann Intern Med 112 (7):: 492-498.
    • (1990) Ann Intern Med , vol.112 , Issue.7 , pp. 492-498
    • Cooper, D.J.1    Walley, K.R.2    Wiggs, B.R.3    Russell, J.A.4
  • 15
    • 17444435790 scopus 로고
    • Systemic effects of NaHCO3 in experimental lactic acidosis in dogs
    • Arieff AI, Leach W, Park R, Lazarowitz VC, (1982) Systemic effects of NaHCO3 in experimental lactic acidosis in dogs. Am J Physiol 242 (6):: F586-F591.
    • (1982) Am J Physiol , vol.242 , Issue.6
    • Arieff, A.I.1    Leach, W.2    Park, R.3    Lazarowitz, V.C.4
  • 16
    • 0022151387 scopus 로고
    • Metabolic effects of sodium bicarbonate in hypoxic lactic acidosis in dogs
    • Graf H, Leach W, Arieff AI, (1985) Metabolic effects of sodium bicarbonate in hypoxic lactic acidosis in dogs. Am J Physiol 249 (5Pt2):: F630-F635.
    • (1985) Am J Physiol , vol.249 , Issue.5 Pt 2
    • Graf, H.1    Leach, W.2    Arieff, A.I.3
  • 17
    • 0021924659 scopus 로고
    • Evidence for a detrimental effect of bicarbonate therapy in hypoxic lactic acidosis
    • Graf H, Leach W, Arieff AI, (1985) Evidence for a detrimental effect of bicarbonate therapy in hypoxic lactic acidosis. Science 227 (4688):: 754-756.
    • (1985) Science , vol.227 , Issue.4688 , pp. 754-756
    • Graf, H.1    Leach, W.2    Arieff, A.I.3
  • 18
    • 0027183677 scopus 로고
    • Carbicarb, sodium bicarbonate, and sodium chloride in hypoxic lactic acidosis. Effect on arterial blood gases, lactate concentrations, hemodynamic variables, and myocardial intracellular pH
    • Rhee KH, Toro LO, McDonald GG, Nunnally RL, Levin DL, (1993) Carbicarb, sodium bicarbonate, and sodium chloride in hypoxic lactic acidosis. Effect on arterial blood gases, lactate concentrations, hemodynamic variables, and myocardial intracellular pH. Chest 104 (3):: 913-918.
    • (1993) Chest , vol.104 , Issue.3 , pp. 913-918
    • Rhee, K.H.1    Toro, L.O.2    McDonald, G.G.3    Nunnally, R.L.4    Levin, D.L.5
  • 19
    • 0027240393 scopus 로고
    • Bicarbonate does not increase left ventricular contractility during L-lactic acidemia in pigs
    • Cooper DJ, Herbertson MJ, Werner HA, Walley KR, (1993) Bicarbonate does not increase left ventricular contractility during L-lactic acidemia in pigs. Am Rev Respir Dis 148 (2):: 317-322.
    • (1993) Am Rev Respir Dis , vol.148 , Issue.2 , pp. 317-322
    • Cooper, D.J.1    Herbertson, M.J.2    Werner, H.A.3    Walley, K.R.4
  • 20
    • 0028007547 scopus 로고
    • Effects of acid-base correction on hemodynamics, oxygen dynamics, and resuscitability in severe canine hemorrhagic shock
    • Benjamin E, Oropello JM, Abalos AM, Hannon EM, Wang JK, et al. (1994) Effects of acid-base correction on hemodynamics, oxygen dynamics, and resuscitability in severe canine hemorrhagic shock. Crit Care Med 22 (10):: 1616-1623.
    • (1994) Crit Care Med , vol.22 , Issue.10 , pp. 1616-1623
    • Benjamin, E.1    Oropello, J.M.2    Abalos, A.M.3    Hannon, E.M.4    Wang, J.K.5
  • 21
    • 0029745104 scopus 로고    scopus 로고
    • Normovolaemic haemodilution attenuates cardiac depression induced by sodium bicarbonate in canine metabolic acidosis
    • Tanaka M, Nishikawa T, Mizutani T, (1996) Normovolaemic haemodilution attenuates cardiac depression induced by sodium bicarbonate in canine metabolic acidosis. Br J Anaesth 77 (3):: 408-412.
    • (1996) Br J Anaesth , vol.77 , Issue.3 , pp. 408-412
    • Tanaka, M.1    Nishikawa, T.2    Mizutani, T.3
  • 22
    • 0031466835 scopus 로고    scopus 로고
    • Acute haemodynamic effects of sodium bicarbonate administration in respiratory and metabolic acidosis in anaesthetized dogs
    • Tanaka M, Nishikawa T, (1997) Acute haemodynamic effects of sodium bicarbonate administration in respiratory and metabolic acidosis in anaesthetized dogs. Anaesth Intensive Care 25 (6):: 615-620.
    • (1997) Anaesth Intensive Care , vol.25 , Issue.6 , pp. 615-620
    • Tanaka, M.1    Nishikawa, T.2
  • 23
    • 50349086366 scopus 로고    scopus 로고
    • Is there a role for sodium bicarbonate in treating lactic acidosis from shock?
    • Boyd JH, Walley KR, (2008) Is there a role for sodium bicarbonate in treating lactic acidosis from shock? Curr Opin Crit Care 14 (4):: 379-383.
    • (2008) Curr Opin Crit Care , vol.14 , Issue.4 , pp. 379-383
    • Boyd, J.H.1    Walley, K.R.2
  • 24
    • 37549020378 scopus 로고    scopus 로고
    • Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008
    • Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, et al. (2008) Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 36 (1):: 296-327.
    • (2008) Crit Care Med , vol.36 , Issue.1 , pp. 296-327
    • Dellinger, R.P.1    Levy, M.M.2    Carlet, J.M.3    Bion, J.4    Parker, M.M.5
  • 25
    • 33745503430 scopus 로고    scopus 로고
    • Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: results of an online survey
    • Kraut JA, Kurtz I, (2006) Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: results of an online survey. Clin Exp Nephrol 10 (2):: 111-117.
    • (2006) Clin Exp Nephrol , vol.10 , Issue.2 , pp. 111-117
    • Kraut, J.A.1    Kurtz, I.2
  • 26
    • 0342748496 scopus 로고    scopus 로고
    • Effect of major hepatectomy on glucose and lactate metabolism
    • Chiolero R, Tappy L, Gillet M, Revelly JP, Roth H, et al. (1999) Effect of major hepatectomy on glucose and lactate metabolism. Ann Surg 229 (4):: 505-513.
    • (1999) Ann Surg , vol.229 , Issue.4 , pp. 505-513
    • Chiolero, R.1    Tappy, L.2    Gillet, M.3    Revelly, J.P.4    Roth, H.5
  • 27
    • 0003259042 scopus 로고    scopus 로고
    • Phoshoexokinase
    • In: S.P.Colowick and N.0.Kaplan, editors Academic Press Inc, New York
    • Ling K H, Byrne W, Lardy H (2010) Phoshoexokinase. In: S.P.Colowick and N.0.Kaplan, editors. Methods in enzymology. Academic Press Inc, New York. pp. 306-310.
    • (2010) Methods in enzymology , pp. 306-310
    • Ling, K.H.1    Byrne, W.2    Lardy, H.3
  • 29
    • 0001124041 scopus 로고
    • Amelioration of hypoxia-induced lactic acidosis by superimposed hypercapnea or hydrochloric acid infusion
    • Abu Romeh S, Tannen RL, (1986) Amelioration of hypoxia-induced lactic acidosis by superimposed hypercapnea or hydrochloric acid infusion. Am J Physiol 250 (4Pt 2):: F702-F709.
    • (1986) Am J Physiol , vol.250 , Issue.4 Pt 2
    • Abu Romeh, S.1    Tannen, R.L.2
  • 30
    • 17544394686 scopus 로고    scopus 로고
    • Impaired hepatic extraction and increased splanchnic production contribute to lactic acidosis in canine sepsis
    • Chrusch C, Bands C, Bose D, Li X, Jacobs H, et al. (2000) Impaired hepatic extraction and increased splanchnic production contribute to lactic acidosis in canine sepsis. Am J Respir Crit Care Med 161 (2Pt 1):: 517-526.
    • (2000) Am J Respir Crit Care Med , vol.161 , Issue.2 Pt 1 , pp. 517-526
    • Chrusch, C.1    Bands, C.2    Bose, D.3    Li, X.4    Jacobs, H.5
  • 31
    • 0036741508 scopus 로고    scopus 로고
    • Blood pH level modulates organ metabolism of lactate in septic shock in dogs
    • Chrusch C, Bautista E, Jacobs HK, Light RB, Bose D, et al. (2002) Blood pH level modulates organ metabolism of lactate in septic shock in dogs. J Crit Care 17 (3):: 188-202.
    • (2002) J Crit Care , vol.17 , Issue.3 , pp. 188-202
    • Chrusch, C.1    Bautista, E.2    Jacobs, H.K.3    Light, R.B.4    Bose, D.5
  • 32
    • 0019992117 scopus 로고
    • Treatment of lactic acidosis with dichloroacetate in dogs
    • Park R, Arieff AI, (1982) Treatment of lactic acidosis with dichloroacetate in dogs. J Clin Invest 70 (4):: 853-862.
    • (1982) J Clin Invest , vol.70 , Issue.4 , pp. 853-862
    • Park, R.1    Arieff, A.I.2
  • 33
    • 33745238726 scopus 로고    scopus 로고
    • Respiratory acidosis: is the correction with bicarbonate worth?
    • Gattinoni L, Taccone P, Carlesso E, (2006) Respiratory acidosis: is the correction with bicarbonate worth? Minerva Anestesiol 72 (6):: 551-557.
    • (2006) Minerva Anestesiol , vol.72 , Issue.6 , pp. 551-557
    • Gattinoni, L.1    Taccone, P.2    Carlesso, E.3
  • 34
    • 0033624116 scopus 로고    scopus 로고
    • The increase in CO2 production induced by NaHCO3 depends on blood albumin and hemoglobin concentrations
    • Levraut J, Garcia P, Giunti C, Ichai C, Bouregba M, et al. (2000) The increase in CO2 production induced by NaHCO3 depends on blood albumin and hemoglobin concentrations. Intensive Care Med 26 (5):: 558-564.
    • (2000) Intensive Care Med , vol.26 , Issue.5 , pp. 558-564
    • Levraut, J.1    Garcia, P.2    Giunti, C.3    Ichai, C.4    Bouregba, M.5
  • 35
    • 0028816683 scopus 로고
    • Changes in end-tidal carbon dioxide tension following sodium bicarbonate administration: correlation with cardiac output and haemoglobin concentration
    • Okamoto H, Hoka S, Kawasaki T, Okuyama T, Takahashi S, (1995) Changes in end-tidal carbon dioxide tension following sodium bicarbonate administration: correlation with cardiac output and haemoglobin concentration. Acta Anaesthesiol Scand 39 (1):: 79-84.
    • (1995) Acta Anaesthesiol Scand , vol.39 , Issue.1 , pp. 79-84
    • Okamoto, H.1    Hoka, S.2    Kawasaki, T.3    Okuyama, T.4    Takahashi, S.5
  • 37
    • 0032541530 scopus 로고    scopus 로고
    • Protection of acid-base balance by pH regulation of acid production
    • Hood VL, Tannen RL, (1998) Protection of acid-base balance by pH regulation of acid production. N Engl J Med 339 (12):: 819-826.
    • (1998) N Engl J Med , vol.339 , Issue.12 , pp. 819-826
    • Hood, V.L.1    Tannen, R.L.2
  • 38
    • 0025264036 scopus 로고
    • Glycogenesis from lactate in rabbit skeletal muscle fiber types
    • Pagliassotti MJ, Donovan CM, (1990) Glycogenesis from lactate in rabbit skeletal muscle fiber types. Am J Physiol 258 (4Pt 2):: R903-R911.
    • (1990) Am J Physiol , vol.258 , Issue.4 Pt 2
    • Pagliassotti, M.J.1    Donovan, C.M.2
  • 39
    • 0036850894 scopus 로고    scopus 로고
    • Lactate and glucose interactions during rest and exercise in men: effect of exogenous lactate infusion
    • Miller BF, Fattor JA, Jacobs KA, Horning MA, Navazio F, et al. (2002) Lactate and glucose interactions during rest and exercise in men: effect of exogenous lactate infusion. J Physiol 544 (Pt3):: 963-975.
    • (2002) J Physiol , vol.544 , Issue.Pt 3 , pp. 963-975
    • Miller, B.F.1    Fattor, J.A.2    Jacobs, K.A.3    Horning, M.A.4    Navazio, F.5
  • 40
    • 0021015795 scopus 로고
    • Ph control of lactic acid and keto acid production a mechanism of acid-base regulation
    • Hood VL, Tannen RL, (1983) Ph control of lactic acid and keto acid production a mechanism of acid-base regulation. Miner Electrolyte Metab 9 (4-6):: 317-325.
    • (1983) Miner Electrolyte Metab , vol.9 , Issue.4-6 , pp. 317-325
    • Hood, V.L.1    Tannen, R.L.2
  • 41
    • 0022657392 scopus 로고
    • Hepatic lactate uptake is enhanced by low pH at low lactate concentrations in perfused rat liver
    • Sestoft L, Marshall MO, (1986) Hepatic lactate uptake is enhanced by low pH at low lactate concentrations in perfused rat liver. Clin Sci Lond 70 (1):: 19-22.
    • (1986) Clin Sci Lond , vol.70 , Issue.1 , pp. 19-22
    • Sestoft, L.1    Marshall, M.O.2
  • 42
    • 0017902428 scopus 로고
    • Effect of varying PCO2 on intracellular pH and lactate consumption in the isolated perfused rat liver
    • Baron PG, Iles RA, Cohen RD, (1978) Effect of varying PCO2 on intracellular pH and lactate consumption in the isolated perfused rat liver. Clin Sci Mol Med 55 (2):: 175-181.
    • (1978) Clin Sci Mol Med , vol.55 , Issue.2 , pp. 175-181
    • Baron, P.G.1    Iles, R.A.2    Cohen, R.D.3
  • 43
    • 0025286025 scopus 로고
    • Lactate and pyruvate transport is dominated by a pH gradient-sensitive carrier in rat skeletal muscle sarcolemmal vesicles
    • Roth DA, Brooks GA, (1990) Lactate and pyruvate transport is dominated by a pH gradient-sensitive carrier in rat skeletal muscle sarcolemmal vesicles. Arch Biochem Biophys 279 (2):: 386-394.
    • (1990) Arch Biochem Biophys , vol.279 , Issue.2 , pp. 386-394
    • Roth, D.A.1    Brooks, G.A.2
  • 44
    • 0033569442 scopus 로고    scopus 로고
    • The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation
    • Halestrap AP, Price NT, (1999) The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. Biochem J 343 (Pt2):: 281-299.
    • (1999) Biochem J , vol.343 , Issue.Pt 2 , pp. 281-299
    • Halestrap, A.P.1    Price, N.T.2
  • 45
    • 0032737751 scopus 로고    scopus 로고
    • Effect of induced metabolic acidosis on human skeletal muscle metabolism during exercise
    • Hollidge-Horvat MG, Parolin ML, Wong D, Jones NL, Heigenhauser GJ, (1999) Effect of induced metabolic acidosis on human skeletal muscle metabolism during exercise. Am J Physiol 277 (4Pt 1):: E647-E658.
    • (1999) Am J Physiol , vol.277 , Issue.4 Pt 1
    • Hollidge-Horvat, M.G.1    Parolin, M.L.2    Wong, D.3    Jones, N.L.4    Heigenhauser, G.J.5
  • 46
    • 31744434996 scopus 로고    scopus 로고
    • Lactate as a marker of energy failure in critically ill patients: hypothesis
    • Valenza F, Aletti G, Fossali T, Chevallard G, Sacconi F, et al. (2005) Lactate as a marker of energy failure in critically ill patients: hypothesis. Crit Care 9 (6):: 588-593.
    • (2005) Crit Care , vol.9 , Issue.6 , pp. 588-593
    • Valenza, F.1    Aletti, G.2    Fossali, T.3    Chevallard, G.4    Sacconi, F.5
  • 47
    • 18744406047 scopus 로고    scopus 로고
    • Lactate utilization as an energy substrate in ischemic preconditioned rat brain slices
    • Kitano T, Nisimaru N, Shibata E, Iwasaka H, Noguchi T, et al. (2002) Lactate utilization as an energy substrate in ischemic preconditioned rat brain slices. Life Sci 72 (4-5):: 557-564.
    • (2002) Life Sci , vol.72 , Issue.4-5 , pp. 557-564
    • Kitano, T.1    Nisimaru, N.2    Shibata, E.3    Iwasaka, H.4    Noguchi, T.5
  • 48
    • 0037727888 scopus 로고    scopus 로고
    • Lactate as a pivotal element in neuron-glia metabolic cooperation
    • Pellerin L, (2003) Lactate as a pivotal element in neuron-glia metabolic cooperation. Neurochem Int 43 (4-5):: 331-338.
    • (2003) Neurochem Int , vol.43 , Issue.4-5 , pp. 331-338
    • Pellerin, L.1
  • 49
    • 0033088410 scopus 로고    scopus 로고
    • Energy metabolism in critically ill patients: lactate is a major oxidizable substrate
    • Leverve XM, (1999) Energy metabolism in critically ill patients: lactate is a major oxidizable substrate. Curr Opin Clin Nutr Metab Care 2 (2):: 165-169.
    • (1999) Curr Opin Clin Nutr Metab Care , vol.2 , Issue.2 , pp. 165-169
    • Leverve, X.M.1
  • 50
    • 0035744770 scopus 로고    scopus 로고
    • Inter-organ substrate exchanges in the critically ill
    • Leverve XM, (2001) Inter-organ substrate exchanges in the critically ill. Curr Opin Clin Nutr Metab Care 4 (2):: 137-142.
    • (2001) Curr Opin Clin Nutr Metab Care , vol.4 , Issue.2 , pp. 137-142
    • Leverve, X.M.1


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