Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewisx levels and impaired neurite outgrowth

Biochimica et Biophysica Acta - General Subjects

Volumn 1820, Issue 12, 2012, Pages 2007-2019

  Gouveia, Ricardo ^a   Schaffer, Lana ^b   Papp, Suzanne ^b   Grammel, Nicolas ^c   Kandzia, Sebastian ^c   Head, Steven R ^b   Kleene, Ralf ^d   Schachner, Melitta ^d   Conradt, Harald S ^c   Costa, Júlia ^a  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c GlycoThera GmbH   (Germany)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Fucosyltransferase 9; Lewis x; Neurite outgrowth; Neuron glycosylation; Neuronal differentiation

Indexed keywords

FUCOSYLTRANSFERASE; FUCOSYLTRANSFERASE 9; GLYCAN; GLYCOGENE; MESSENGER RNA; NERVE CELL ADHESION MOLECULE L1; POLYSIALIC ACID; SIALYLTRANSFERASE; SULFOTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROARRAY ANALYSIS; NERVE FIBER GROWTH; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN TRANSPORT; UNINDEXED SEQUENCE; UPREGULATION;

AMINO ACID SEQUENCE; ANTIGENS, CD15; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; DOWN-REGULATION; FUCOSYLTRANSFERASES; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; IMMUNOPRECIPITATION; MOLECULAR SEQUENCE DATA; NEURAL CELL ADHESION MOLECULES; NEURITES; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; POLYSACCHARIDES; SIALIC ACIDS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84867002594     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.09.004     Document Type: Article

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