Susceptibility of helicobacter pylori to natural products: Can past research direct future drug development?

Current Bioactive Compounds

Volumn 8, Issue 3, 2012, Pages 266-276

  Lawal, Temitope O ^a   Soni, Kapil K ^b   Doyle, Brian J ^c   Adeniyi, Bolanle A ^a   Mahady, Gail B ^b  

^a UNIVERSITY OF IBADAN   (Nigeria)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c ALMA COLLEGE   (United States)

Author keywords

Ethnomedicine; Gastritis; Helicobacter pylori; Natural products; Peptic ulcer disease

Indexed keywords

AMOXICILLIN; BERBERINE; BISMUTH SALT; CHELERYTHRINE; CINNAMONUM ZEYLANICUM EXTRACT; CLARITHROMYCIN; GAMMA LACTONE DERIVATIVE; GARLIC EXTRACT; HYDRASTINE; ISOQUINOLINE ALKALOID; METRONIDAZOLE; NATURAL PRODUCT; PLANT EXTRACT; PROTOLICHESTERINIC ACID; PROTOPINE; PSORALEA CORYLIFOLIA EXTRACT; RESVERATROL; SANGUINARINE; TERPINEN 4 OL; TETRACYCLINE; THYMUS VULGARIS EXTRACT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; BACTERIAL GROWTH; BACTERIAL STRAIN; CHEMOPROPHYLAXIS; DIARRHEA; DISEASE ASSOCIATION; DIZZINESS; DOSE RESPONSE; DRUG INDUCED HEADACHE; DUODENUM ULCER; HELICOBACTER INFECTION; HUMAN; IN VITRO STUDY; INFECTION RATE; KIDNEY FUNCTION; MARGINAL ZONE LYMPHOMA; MEDICINAL PLANT; MINIMUM INHIBITORY CONCENTRATION; NAUSEA; PARESTHESIA; PATIENT COMPLIANCE; PRIORITY JOURNAL; RED WINE; REVIEW; STOMACH ADENOCARCINOMA; STOMACH CANCER; TRADITIONAL MEDICINE;

EID: 84867002338     PISSN: 15734072     EISSN: 18756646     Source Type: Journal    
DOI: 10.2174/157340712802762447     Document Type: Review

References (70)

1. Graham, D.Y. Evolution of concepts regarding Helicobacter pylori: from a cause of gastritis to a public health problem. Am. J. Gastroenterol., 1989, 89, 469-472.
2. Frigo, P.; Lang, C.; Reisenberger, K.; Kolb, H.; Hirschl, A.M. Hyperemesis gravidarum associated with Helicobacter pylori seropositivity. Obstet. Gynecol., 1998, 91, 615-617.
3. Goodwin, C.S. Helicobacter pylori gastritis, peptic ulcer, and gastric cancer: clinical and molecular aspects. Clin. Infect. Dis., 1997, 25, 1017-1019.
4. Hohenberger, P. Gretschel, S. Gastric cancer. Lancet, 2003, 362(9380), 305-315.
5. Laine, L.; Fendrick, A.M. Helicobacter pylori peptic ulcer disease. Bridging the gap between knowledge and treatment. Postgrad. Med., 1998, 103, 231-238.
6. Lindsberg, P.J.; Grau, A.J. Inflammation and infections as risk factors for ischemic stroke. Stroke, 2003, 4, 2518-2532.
7. Moss, S.F.; Sood, S. Helicobacter pylori. Curr. Opin. Infect. Dis., 2003, 16, 445-451.
8. Bhattacharyya, A.; Pathak, S.; Datta, S.; Chattopadhyay, S.; Basu, J.; Kundu, M. Mitogen-activated protein kinases and nuclear factor-kappaB regulate Helicobacter pylori-mediated interleukin-8 release from macrophages. Biochem. J., 2002, 368, 121-129.
9. Lindkvist, P.; Asrat, D.; Nilsson, I.; Tsega, E.; Olsson, GL.; Wretlind, B.; Giesecke, J. Age acquisition of Helicobacter pylori infection: Comparison of a high and a low prevalence country. Scand. J. Infect. Dis., 1996, 28, 181-184.
10. Frenck, R.W.; Clemens, J. Helicobacter in the developing world. Microbes Infect., 2003, 5, 705-713.
11. Ramirez-Ramos, A.; Gilman, RH.; Leon-Barua, R.; Recavarren-Arce, S.; Watanabe, J. Rapid recurrence of Helicobacter pylori infection in Peruvian patients after successful eradication. Clin. Infect. Dis., 1997, 25,1027-1031.
12. IARC Working Group. Schistosomes, liver flukes and Helicobacter pylori. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, 7-14 June 1994. IARC Monogr. Eval. Carcinog. Risks Hum., 1994, 61, 1-241.
13. Lamarque, D.; Tran, V.N.J.; Breban, M. [What are the gastric modifications induced by acute and chronic Helicobacter pylori infection?] [Article in French]. Gastroenterol. Clin. Biol., 2003, 27, 391-400.
14. Perri, F.; Qasim, A.; Marras, L.; O'Morain, C. Treatment of Helicobacter pylori infection. Helicobacter, 2003, 8, 53-60.
15. Malfertheiner, P.; Megraud, F.; O'Morain, C.A.; Atherton, J.; Axon, A.T.; Bazzoli, F.; Gensini, G.F.; Gisbert, J.P.; Graham, D.Y.; Rokkas, T.; El-Omar, E.M.; Kuipers, E.J. The European Helicobacter Study Group (EHSG). Management of Helicobacter pylori infection--the Maastricht IV/ Florence Consensus Report. Gut, 2012, 61, 646-664.
16. Bayerdörffer, E.; Neubauer, A.; Rudolph, B. Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. Lancet, 1995, 345,1591-1594.
17. Rubin, W. Medical treatment of peptic ulcer disease. Med. Clin. N. Am., 1991, 75, 981-998.
18. Gutierrez, O.; Angel, A.; Segura, A.M.; Genta, R.M.; Graham, D.Y. Effectiveness of triple therapy for Helicobacter pylori in countries where metronidazole resistance is common. Gastroenterology, 1996, 110, A126.
19. Megraud, F. Helicobacter pylori resistance: prevalence, importance and advances in testing. Gut, 2004, 53, 1374-1384.
20. Sjolund, M.; Wreiber, K.; Andersson, D.I.; Blaser, MJ.; Engstrand L. Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori. Ann. Intern. Med., 2003, 139, 483-487.
21. Duck, W.M.; Sobel, J.; Pruckler, J.M.; Song, Q.; Swerdlow, D.; Friedman, C.; Sulka, A.; Swaminathan, B.; Taylor, T.; Hoekstra, M.; Griffin, P.; Smoot, D.; Peek, R.; Metz, D.C.; Bloom, P.B.; Goldschmidt, S.; Parsonnet, J.; Triadafilopoulos, G.; Perez-Perez, G.I.; Vakil, N.; Ernst, P.; Czinn, S.; Dunne, D.; Gold, B.D. Antimicrobial resistance incidence and risk factors among Helicobacter pylori-infected persons, United States. EID, 2004, 10(6), 1088-1094.
22. Bhamarapravati, S.; Pendland, S.L.; Mahady, G.B. Extracts of spice and food plants from Thai traditional medicine inhibit the growth of the human carcinogen Helicobacter pylori. In Vivo, 2003, 17(6), 541-544.
23. Cassel-Beraud, A.M.; Le Jan, J.; Mouden, J.C.; Andriantsoa, M.; Andriantsiferana, R. Preliminary study of the prevalence of Helicobacter pylori in Tananarive, Madagascar and the antibacterial activity in vitro of 13 Malagasy medicinal plants on this germ. Arch. Inst. Pasteur. Madagascar, 1991, 59, 9-23.
24. Fabry, W.; Okemo, P.; Ansorg, R. Activity of East African medicinal plants against Helicobacter pylori. Chemotherapy, 1996, 42, 315-317.
25. Tabak, M.; Armon, R.; Potasman, I.; Neeman, I. In vitro inhibition of Helicobacter pylori by extracts of thyme. J. Appl. Bacteriol., 1996, 80, 667-672.
26. Sivam, G.P.; Lampe, J.W.; Ulness, B.; Swanzy, S.R.; Potter, J.D. Helicobacter pylori in vitro susceptibility to garlic (Allium sativum) extract. Nutr. Can., 1997, 27, 118-121.
27. Shinchi, K.; Ishii, H.; Imanishi, K.; Kono, S. Relationship of cigarette smoking, alcohol use, and dietary habits with Helicobacter pylori in Japanese men. Scand. J. Gastroenterol., 1997, 32, 651-655.
28. O'Gara, E.A.; Hill, D.J.; Maslin, D.J. Activities of garlic oil, garlic powder, and their diallyl constituents against Helicobacter pylori. Appl. Environ. Microbiol., 2000, 66(5), 2269-2273.
29. Kadota, S.; Basnet, P.; Ishii, E.; Tamura, T.; Namba, T. Antibacterial activity of trichorabdal A from Rabdosia trichocarpa against Helicobacter pylori. Zentralbl. Bakteriol., 1997, 286, 63-67.
30. Ingolfsdottir, K.; Hjalmarsdottir, M.A.; Sigurdsson, A.; Gudjonsdottir, G.A.; Brynjolfsdottir, A.; Steingrimsson, O. In vitro susceptibility of Helicobacter pylori to protolμ ichesterinic acid from the lichen Cetraria islandica. Antimicrob. Agents Chemother., 1997, 41, 215-217.
31. Yesilada, E.; Gurbuz, I.; Shibata, H. Screening of Turkish antiulcerogenic folk remedies for anti-Helicobacter pylori activity. J. Ethnopharmacol., 1999, 66, 289-293.
32. Hamasaki, N.; Ishii, E.; Tominaga, K.; Tezuka, Y.; Nagaoka, T.; Kadota, S.; Kuroki, T.; Yano, I. Highly selective antibacterial activity of novel alkyl quinolone alkaloids from a Chinese herbal medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori in vitro. Microbiol. Immunol., 2000, 44, 9-15.
33. Mahady, G.B.; Pendland, S.L. Red wine and resveratrol inhibit the growth of Helicobacter pylori in vitro. Am. J. Gastroenterol., 2000, 95, 1849.
34. Mahady, G.B.; Pendland, S.L.; Chadwick, L.R. Resveratrol and red wine extracts inhibit the growth of CagA+ strains of Helicobacter pylori in vitro. Am. J. Gastroenterol., 2003b, 98, 1440-1441.
35. Mahady, G.B.; Pendland, S.L. Garlic and Helicobacter pylori. Am. J. Gastroenterol., 1999, 95, 309-310.
36. Mahady, G.B.; Matsuura, H.; Pendland, S.L. Allixin, a phytoalexin from garlic inhibits the growth of Helicobacter pylori in vitro. Am. J. Gastroenterol., 2001, 96, 3454-3455.
37. Gadhi, C.A.; Benharref, A.; Jana, M.; Lozniewski, A. Anti-Helicobacter pylori activity of Aristolochia paucinervis pomel extracts. J. Ethnopharmacol., 2001, 75, 203-205.
38. Mahady, G.B.; Pendland, S.L.; Yun, G.S.; Lu, Z.Z.; Stoia, A. Ginger (Zingiber officinale Roscoe) and the gingerols inhibit the growth of Cag A+ strains of Helicobacter pylori. Anticancer Res., 2003a, 23, 3699-3702.
39. Mahady, G.B.; Pendland, S.L.; Yun, G.; Lu, Z.Z. Turmeric (Curcuma longa) and curcumin inhibit the growth of Helicobacter pylori, a group 1 carcinogen. Anticancer Res., 2002, 22, 4179-4181.
40. Mahady, G.B.; Pendland, S.L.; Stoia, A.; Chadwick, L. In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis. Phytother. Res., 2003c, 17, 217-221.
41. Matsubara, S.; Shibata, H.; Ishikawa, F.; Yokokura, T.; Takahashi, M.; Sugimura, T.; Wakabayashi, K. Suppression of Helicobacter pylori-induced gastritis by green tea extract in Mongolian gerbils. Biochem. Biophys. Res. Commun., 2003, 310(3), 715-719.
42. Konstantinopoulou, M.; Karioti, A.; Skaltsas, S.; Skaltsa, H. Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity. J. Nat. Prod., 2003, 66(5), 699-702.
43. Mahady, G.B.; Pendland, S.L.; Stoia, A.; Hamill, F.A.; Fabricant, D.; Dietz, B.M.; Chadwick, L.R. In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother. Res., 2005, 19(11), 988-991.
44. Li, Y.; Xu, C.; Zhang, Q.; Liu, J.Y.; Tan, R.X. In vitro anti-Helicobacter pylori action of 30 Chinese herbal medicines used to treat ulcer diseases. J. Ethnopharmacol., 2005, 98, 329-333.
45. Haristoy, X.; Fahey, J.W.; Scholtus, I.; Lozniewski, A. Evaluation of the antimicrobial effects of several isothiocyanates on Helicobacter pylori. Planta Med., 2005, 71, 326-330.
46. Ustün, O.; Ozçelik, B.; Akyön, Y.; Abbasoglu, U.; Yesilada, E. Flavonoids with anti-Helicobacter pylori activity from Cistus laurifolius leaves. J. Ethnopharmacol., 2006, 108, 457-461.
47. Yin, S.; Fan, C.; Dong, L.; Yue, J. Psoracorylifols A-E, five novel compounds with activity against Helicobacter pylori from seeds of Psoralea corylifolia. Tetrahedron, 2006, 62(11), 2569-2575.
48. Stege, P.W.; Davicino, R.C.; Vega, A.E.; Casali, Y.A.; Correa, S.; Micalizzi, B. Antimicrobial activity of aqueous extracts of Larrea divaricata Cav (jarilla) against Helicobacter pylori. Phytomedicine, 2006, 13(9-10), 724-727.
49. Rüegg, T.; Calderón, A.I.; Queiroz, E.F.; Solís, P.N.; Marston, A.; Rivas, F.; Ortega-Barría, E.; Hostettmann, K.; Gupta, M.P. 3-Farnesyl-2-hydroxybenzoic acid is a new anti-Helicobacter pylori compound from Piper multiplinervium. J. Ethnopharmacol., 2006, 103, 461-467.
50. Epifano, F.; Menghini, L.; Pagiotti, R.; Angelini, P.; Genovese, S.; Curini, M. In vitro inhibitory activity of boropinic acid against Helicobacter pylori. Bioorg. Med. Chem. Lett., 2006, 16(21), 5523-5525.
51. Castillo-Juárez, I.; Rivero-Cruz, F.; Celis, H.; Romero, I. Anti-Helicobacter pylori activity of anacardic acids from Amphipterygium adstringens. J. Ethnopharmacol., 2007, 114(1), 72-77.
52. Zhu, Y.; Zhang, P.; Yu, H.; Li, J.; Wang, M.W.; Zhao, W. Anti-Helicobacter pylori and thrombin inhibitory components from Chinese dragon's blood, Dracaena cochinchinensis. J. Nat. Prod., 2007, 70(10), 1570-1577.
53. Castillo-Juárez, I.; González, V.; Jaime-Aguilar, H.; Martínez, G.; Linares, E.; Bye, R.; Romero, I. Anti-Helicobacter pylori activity of plants used in Mexican traditional medicine for gastrointestinal disorders. J. Ethnopharmacol., 2009, 122, 402-405.
54. Zaidi, S.F.; Yoshida, I.; Butt, F.; Yusuf, M.A.; Usmanghani, K.; Kadowaki, M.; Sugiyama, T. Potent bactericidal constituents from Mallotus philippinensis against clarithromycin and metronidazole resistant strains of Japanese and Pakistani Helicobacter pylori. Biol. Pharm. Bull., 2009, 32(4), 631-636.
55. Vega, A.E.; Wendel, G.H.; Maria, A.O.; Pelzer, L. Antimicrobial activity of Artemisia douglasiana and dehydroleucodine against Helicobacter pylori. J. Ethnopharmacol., 2009, 124, 653-655.
56. Wang, Y.; Li, W.; Wu, D.; Wang, J.; Wu, C.; Liao, J.; Lin, C. In vitro activity of 2-methoxy-1, 4-naphthoquinone and stigmasta-7, 22-diene-3β-ol from Impatiens balsamina L. against multiple antibiotic-resistant Helicobacter pylori. Evid. Based Complement. Altern. Med., 2011, Article ID 704721, 8 pages, doi:10.1093/ecam/nep147.
57. Molinari, P.; Deli, J.; Tanaka, T.; Kann, Y.; Tani, S.; Gyémánt, N.; Molnár, J.; Kawase, M. Carotenoids with anti-Helicobacter pylori activity from Golden delicious apple. Phytother. Res., 2010, 24(5), 644-648.
58. Niehues, M.; Stark, T.; Keller, D.; Hofmann, T.; Hensel, A. Antiadhesion as a functional concept for prevention of pathogens: N-Phenylpropenoyl-L-amino acid amides as inhibitors of the Helicobacter pylori BabA outer membrane protein. Mol. Nutr. Food Res., 2011, 55(7), 1104-1117.
59. Suk, K. T.; Baik, S. K.; Kim, H. S.; Park, S. M.; Paeng, K. J.; Uh, Y.; Jang, I. H.; Cho, M. Y.; Choi, E. H.; Kim, M. J.; Ham, Y. L. Antibacterial effects of the urushiol component in the sap of the lacquer tree (Rhus verniciflua Stokes) on Helicobacter pylori. Helicobacter, 2011, 16, 434-443.
60. Njume, C.; Afolayan, A.J.; Green, E.; Ndip, R.N. Volatile compounds in the stem bark of Sclerocarya birrea (Anacardiaceae) possess antimicrobial activity against drug-resistant strains of Helicobacter pylori. Int. J. Antimicrob. Agents, 2011, 38, 319-324.
61. Zhang, F.; Liao, S.; Zhang, C.; He, X.; Chen, W.; Yue, J. Limonoids and diterpenoids from Toona ciliata Roem. var. yunnanensis. Planta Med., 2011, 77(14), 1617-1622.
62. Sakunpak, A.; Panichayupakaranant, P.; Antibacterial activity of Thai edible plants against gastrointestinal pathogenic bacteria and isolation of a new broad spectrum antibacterial polyisoprenylated benzophenone, chamuangone. Food Chem., 2012, 130, 826-831.
63. Owen, D.A. Gastritis and carditis. Mod. Pathol., 2003, 16, 325-341.
64. Isenberg, J.I. Acid-peptic disorders. In: Textbook of Gastroenterology; Yamada, T.; Alpers, D.H.; Owyang, C.; Eds., JB Lippincott Co: Philadelphia, 1992; pp. 1231-1234.
65. Chuah, S.K.; Tsay, F.W.; Hsu, P.I.; Wu, D. A new look at anti-Helicobacter pylori therapy. World J. Gastroenterol., 2011, 17(35), 3971-3975.
66. Gisbert, J.P.; Calvet X. Review article: the effectiveness of standard triple therapy for Helicobacter pylori has not changed over the last decade, but it is not good enough. Aliment Pharmacol. Ther., 2011, 34(11-12), 1255-1268.
67. Maev, I.V.; Samsonov, A.A.; Golubev, N.N. [Helicobacter pylori: what schemes of eradication are essential today?]. [Article in Russian] Ter. Arkh., 2011, 83(8), 41-44.
68. Graham, D.Y.; Fischbach, L. Helicobacter pylori treatment in the era of increasing antibiotic resistance. Gut, 2010, 59(8), 1143-1153.
69. Misselwitz, B.; Kaiser, P.; Bauerfeind, P.; Vavricka, S.R [New options for Helicobacter pylori antibiotic treatment]. Dtsch. Med. Wochenschr., 2011, 136(28-29), 1479-1484.
70. Selgrad, M.; Malfertheiner, P. Treatment of Helicobacter pylori. Curr. Opin. Gastroenterol., 2011, 27(6), 565-570.