Balloon catheter delivery of helper-dependent adenoviral vector results in sustained, therapeutic hFIX expression in rhesus macaques

Molecular Therapy

Volumn 20, Issue 10, 2012, Pages 1863-1870

  Brunetti Pierri, Nicola ^a,b,e   Liou, Aimee ^a   Patel, Priti ^a,f   Palmer, Donna ^a   Grove, Nathan ^a   Finegold, Milton ^a   Piccolo, Pasquale ^b   Donnachie, Elizabeth ^c   Rice, Karen ^d   Beaudet, Arthur ^a   Mullins, Charles ^a   Ng, Philip ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d SOUTHWEST NATIONAL PRIMATE RESEARCH CENTER   (United States)

^e UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^f Children's Hospital of Illinois   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BLOOD CLOTTING FACTOR 9 INHIBITOR; BLOOD CLOTTING INHIBITOR; DNA; HELPER DEPENDENT ADENOVIRUS VECTOR; RECOMBINANT BLOOD CLOTTING FACTOR 9; UNCLASSIFIED DRUG; VIRUS VECTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BALLOON CATHETER; BALLOON OCCLUSION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG TOLERABILITY; GENETIC TRANSDUCTION; HEMOPHILIA; HEMOPHILIA B; LIVER; LIVER CELL; MALE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; RHESUS MONKEY; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS PARTICLE;

ANIMALIA; MACACA MULATTA;

EID: 84866986951     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2012.143     Document Type: Article

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