Methods for the production of first generation adenoviral vectors

Methods in Molecular Biology

Volumn 433, Issue , 2008, Pages 55-78

  Palmer, Donna J ^a   Ng, Philip ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Adenovirus; Cre; E1; FLP; Frt; Gene therapy; Large scale; LoxP; Spinner; Suspension; Vector

Indexed keywords

ADENOVIRIDAE; MAMMALIA;

EID: 84934437167     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-237-3_4     Document Type: Article

References (25)

1. Shenk, T. (1996) Adenoviridae: the viruses and their replication. In Fields Viology (Eds., Fields B. N., Knipe D.M., Howely P. M) pp. 2111-2148. Lipponcott-Raven Publishers, Philadelphia, PA.
2. Bergelson, J. M., Cunningham. J. A., Droguett G, et al. (1997) Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science 275, 1320-1323.
3. Hong, S. S., Karayan, L., Tournier, J., Curiel, D. T., and Boulanger, P. A. (1997) Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells. Embo J. 16, 2294-2306.
4. Wickham, T. J., Mathias, P., Cheresh, D. A., and Nemerow, G. R.(1993) Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 73, 309-319.
5. Wickham, T. J., Segal, D. M., Roelvink, P. W., et al. (1996) Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies. J Virol. 70, 6831-6838.
6. Goldman, M., Su, Q., and Wilson, J. M. (1996) Gradient of RGD-dependent entry of adenoviral vector in nasal and intrapulmonary epithelia: implications for gene therapy of cystic fibrosis. Gene Ther. 3, 811-818.
7. Mellman, I. (1992) The importance of being acidic: the role of acidification in intracellular membrane traffic. J. Exp. Biol. 172, 39-45.
8. Leopold, P. L., Ferris, B., Grinberg, I., Worgall, S., Hackett, N. R., and Crystal, R. G. (1998) Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells. Hum. Gene Ther. 9, 367-378.
9. Greber, U. F., Willetts, M., Webster, P., and Helenius, A. (1993) Stepwise dismantling of adenovirus 2 during entry into cells. Cell 75,477-486; Berkner, K. L. (1988) Development of adenovirus vectors for expression of heterologous genes. Biotechniques 6, 616-629.
10. Graham, F. L., and Prevec, L. (1992) Adenovirus-based expression vectors and recombinant vaccines. In Vaccines: New Approaches to Immunological Problems (Ed. R. W. Ellis) pp. 363-389. Butterworth-Heinemann, Boston, MA.
11. Hitt, M., Addison, C. L., and Graham, F. L. (1997) Human adenovirus vectors for gene transfer into mammalian cells. Adv. Pharmacol. 40, 137-206.
12. Hitt, M. M., Parks, R. J., and Graham, F. L. (1999) Structure and genetic organization of adenovirus vectors. In The Development of Human Gene Therapy (Ed. T. Friedman) pp.61-86. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
13. Tatsis, N. and Ert, H.C.J. (2005) Adenoviruses as vaccine vectors. Mol. Ther. 10, 616-629.
14. Graham, F. L., Smiley, J., Russell, W. C., and Nairn, R. (1977) Characteristics of a human cell line transformed by DNA from human adenovirus 5. J. Gen. Viol. 36, 59-72.
15. Danthainne, X., and Imperiale, M. J. (2000) Production of first generation adenovirus vectors: a review. Gene Ther. 7, 1707-1714.
16. Ng, P., Parks, R. J., Cummings, D. T., Evelegh, C. M., Sankar, U., and Graham F. L. (1999) A high efficiency Cre/loxP based system for construction of adenoviral vectors. Hum. Gene Ther. 10, 2667-2672.
17. Ng, P., Parks, R. J., Cummings, D. T., Evelegh, C. M., and Graham, F. L. (2000) An enhanced system for construction of adenoviral vectors by the two plasmid rescue method. Hum. Gene Ther. 11, 693-699.
18. Ng, P., Cummings, D. T, Evelegh, C. M., and Graham, F. L. (2000) The yeast recombinase flp functions effectively in human cells for construction of adenovirus vectors. Biotechniqes 29, 524-528.
19. Graham, F. L. (1984) Covalently closed circles of human adenovirus DNA are infectious. EMBO J. 3, 2917-2922.
20. Bett, A. J., Prevec, L., and Graham, F. L. (1993) Packaging capacity and stability of human adenovirus type 5 vectors. J. Virol. 67, 5911-5921.
21. Addison, C. L., Hitt, M., Kunsken, D., and Graham, F. L. (1997). Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors. J. Gen. Virol. 78, 1653-1661.
22. Graham, F. L. (1987) Growth of 293 cells in suspension culture. J. Gen. Virol. 68, 937-940.
23. Maizel, J. V., White, D., and Scharff, M. D. (1968) The polypeptides of adenovirus. I. Evidence of multiple protein components in the virion and a comparison of types 2, 7a, and 12. Virology 36, 115-125.
24. Louis, N., Evelegh, C., and Graham, F. L. (1997) Cloning and sequencing of the cellular/viral junction from the human adenovirus type 5 transformed 293 cell line. Virology 233, 423-429.
25. Lochmuller, H., Jani, A., Haurd, J. Prescott, S., Simoneau, M., Massie, B., Karpati, G., and Acsadi, G. (1994) Emergence of early region 1-containing replication-competent adenovirus in stocks of replication-defective adenovirus recombinants (ΔE1+ΔE3) during multiple passages in 293 cells. Hum. Gene Ther. 5, 1485-1491.