A modular fibrinogen model that captures the stress-strain behavior of fibrin fibers

Biophysical Journal

Volumn 103, Issue 7, 2012, Pages 1537-1544

  Averett, Rodney D ^a   Menn, Bryant ^a   Lee, Eric H ^c,d   Helms, Christine C ^b   Barker, Thomas ^a   Guthold, Martin ^b  

^a Emory University   (United States)

^b WAKE FOREST UNIVERSITY   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRIN; FIBRINOGEN;

ANIMAL; ARTICLE; BIOMECHANICS; BLOOD CLOTTING; CATTLE; CHEMISTRY; ELASTICITY; MECHANICAL STRESS; METABOLISM; MOLECULAR DYNAMICS; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE;

ANIMALS; BIOMECHANICS; BLOOD COAGULATION; CATTLE; ELASTICITY; FIBRIN; FIBRINOGEN; MOLECULAR DYNAMICS SIMULATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; STRESS, MECHANICAL;

EID: 84866981523     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2012.08.038     Document Type: Article

References (40)

1. M.E. Carr Jr., and S.L. Zekert Measurement of platelet-mediated force development during plasma clot formation Am. J. Med. Sci. 302 1991 13 18
2. E. Rubenstein Blood clotting: the force of retraction Science 138 1962 1343 1344
3. J.R. Houser, and N.E. Hudson M.R. Falvo Evidence that αC region is origin of low modulus, high extensibility, and strain stiffening in fibrin fibers Biophys. J. 99 2010 3038 3047
4. W. Liu, and C.R. Carlisle M. Guthold The mechanical properties of single fibrin fibers J. Thromb. Haemost. 8 2010 1030 1036
5. W. Liu, and L.M. Jawerth M. Guthold Fibrin fibers have extraordinary extensibility and elasticity Science 313 2006 634
6. A.E.X. Brown, and R.I. Litvinov J.W. Weisel Multiscale mechanics of fibrin polymer: gel stretching with protein unfolding and loss of water Science 325 2009 741 744
7. J.W. Weisel Fibrinogen and fibrin A.D.P. David, M.S. John, Advances in Protein Chemistry 2005 Academic Press New York 247 299
8. R.F. Doolittle Fibrinogen and fibrin Annu. Rev. Biochem. 53 1984 195 229
9. R.R. Hantgan, and J. Hermans Assembly of fibrin. A light scattering study J. Biol. Chem. 254 1979 11272 11281
10. J.W. Weisel, and L. Medved The structure and function of the α-C domains of fibrinogen Ann. N. Y. Acad. Sci. 936 2001 312 327
11. Y.I. Veklich, and O.V. Gorkun J.W. Weisel Carboxyl-terminal portions of the α-chains of fibrinogen and fibrin. Localization by electron microscopy and the effects of isolated α-C fragments on polymerization J. Biol. Chem. 268 1993 13577 13585
12. B.B.C. Lim, and E.H. Lee K. Schulten Molecular basis of fibrin clot elasticity Structure 16 2008 449 459
13. A. Zhmurov, and A.E. Brown V. Barsegov Mechanism of fibrin(ogen) forced unfolding Structure 19 2011 1615 1624
14. A.E. Brown, and R.I. Litvinov J.W. Weisel Forced unfolding of coiled-coils in fibrinogen by single-molecule AFM Biophys. J. 92 2007 L39 L41
15. J.-P. Collet, and J.L. Moen J.W. Weisel The α-C domains of fibrinogen affect the structure of the fibrin clot, its physical properties, and its susceptibility to fibrinolysis Blood 106 2005 3824 3830
16. A.S.C. Soon, and S.E. Stabenfeldt T.H. Barker Engineering fibrin matrices: the engagement of polymerization pockets through fibrin knob technology for the delivery and retention of therapeutic proteins Biomaterials 31 2010 1944 1954
17. A. Stéphanou, and G. Meskaoui P. Tracqui The rigidity in fibrin gels as a contributing factor to the dynamics of in vitro vascular cord formation Microvasc. Res. 73 2007 182 190
18. L. Urech, and A.G. Bittermann H. Hall Mechanical properties, proteolytic degradability and biological modifications affect angiogenic process extension into native and modified fibrin matrices in vitro Biomaterials 26 2005 1369 1379
19. C.C. Helms, and R.A.S. Ariëns M. Guthold α-α Crosslinks increase fibrin fiber elasticity and stiffness Biophys. J. 102 2012 168 175
20. C.R. Carlisle, and E.A. Sparks M. Guthold Strength and failure of fibrin fiber branchpoints J. Thromb. Haemost. 8 2010 1135 1138
21. M.R. Falvo, and D. Millard S.T. Lord Length of tandem repeats in fibrin's α-C region correlates with fiber extensibility J. Thromb. Haemost. 6 2008 1991 1993
22. M. Guthold, and S.S. Cho Fibrinogen unfolding mechanisms are not too much of a stretch Structure 19 2011 1536 1538
23. L.E. Averett, and C.B. Geer M.H. Schoenfisch Complexity of "A-a" knob-hole fibrin interaction revealed by atomic force spectroscopy Langmuir 24 2008 4979 4988
24. O.V. Gorkun, and Y.I. Veklich J.W. Weisel Role of the α-C domains of fibrin in clot formation Biochemistry 33 1994 6986 6997
25. G. Tsurupa, L. Tsonev, and L. Medved Structural organization of the fibrin(ogen) α-C-domain Biochemistry 41 2002 6449 6459
26. C.R. Carlisle, and C. Coulais M. Guthold The mechanical properties of individual, electrospun fibrinogen fibers Biomaterials 30 2009 1205 1213
27. R.A. Burton, and G. Tsurupa N. Tjandra Identification of an ordered compact structure within the recombinant bovine fibrinogen αC-domain fragment by NMR Biochemistry 45 2007 2257 2266
28. J.C. Phillips, and R. Braun K. Schulten Scalable molecular dynamics with NAMD J. Comput. Chem. 26 2005 1781 1802
29. W. Humphrey, A. Dalke, and K. Schulten VMD: visual molecular dynamics J. Mol. Graph. 14 1996 27 38
30. J.F. Marko, and E.D. Siggia Stretching DNA Macromolecules 28 1995 8759 8770
31. M. Guthold, and W. Liu R. Superfine Visualization and mechanical manipulations of individual fibrin fibers suggest that fiber cross section has fractal dimension 1.3 Biophys. J. 87 2004 4226 4236
32. M.E. Carr Jr., and J. Hermans Size and density of fibrin fibers from turbidity Macromolecules 11 1978 46 50
33. W.A. Voter, C. Lucaveche, and H.P. Erickson Concentration of protein in fibrin fibers and fibrinogen polymers determined by refractive index matching Biopolymers 25 1986 2375 2384
34. A.F. Oberhauser, and P.E. Marszalek J.M. Fernandez The molecular elasticity of the extracellular matrix protein tenascin Nature 393 1998 181 185
35. M. Rief, and M. Gautel H.E. Gaub Reversible unfolding of individual titin immunoglobulin domains by AFM Science 276 1997 1109 1112
36. C.C. Helms, and R.A. Ariëns M. Guthold α-α Cross-links increase fibrin fiber elasticity and stiffness Biophys. J. 102 2012 168 175
37. J. Hsin, and K. Schulten Improved resolution of tertiary structure elasticity in muscle protein Biophys. J. 100 2011 L22 L24
38. E.H. Lee, and J. Hsin K. Schulten Discovery through the computational microscope Structure 17 2009 1295 1306
39. H.C. Andersen Molecular dynamics simulations at constant pressure and/or temperature J. Chem. Phys. 72 1980 2384 2393
40. T. Hill An Introduction to Statistical Thermodynamics 1960, 1986 Addison-Wesley, and Dover Dover, DE